CN1087267A - A kind of prescription for the treatment of seborrheic alopecia - Google Patents
A kind of prescription for the treatment of seborrheic alopecia Download PDFInfo
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- CN1087267A CN1087267A CN 92113387 CN92113387A CN1087267A CN 1087267 A CN1087267 A CN 1087267A CN 92113387 CN92113387 CN 92113387 CN 92113387 A CN92113387 A CN 92113387A CN 1087267 A CN1087267 A CN 1087267A
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- 201000004384 Alopecia Diseases 0.000 title claims abstract description 31
- 231100000360 alopecia Toxicity 0.000 title claims abstract description 30
- 239000003814 drug Substances 0.000 claims abstract description 23
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- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims abstract description 13
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 13
- 235000019155 vitamin A Nutrition 0.000 claims abstract description 13
- 239000011719 vitamin A Substances 0.000 claims abstract description 13
- 229940045997 vitamin a Drugs 0.000 claims abstract description 13
- 241001597008 Nomeidae Species 0.000 claims abstract description 11
- 230000003779 hair growth Effects 0.000 claims abstract description 7
- 210000000582 semen Anatomy 0.000 claims description 8
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims description 4
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 4
- 241000756943 Codonopsis Species 0.000 claims description 3
- 239000009636 Huang Qi Substances 0.000 claims description 3
- 230000003203 everyday effect Effects 0.000 claims description 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 3
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims description 2
- LEVWYRKDKASIDU-QWWZWVQMSA-N D-cystine Chemical compound OC(=O)[C@H](N)CSSC[C@@H](N)C(O)=O LEVWYRKDKASIDU-QWWZWVQMSA-N 0.000 claims description 2
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 claims description 2
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims description 2
- 229930003270 Vitamin B Natural products 0.000 claims description 2
- 230000037396 body weight Effects 0.000 claims description 2
- 239000002775 capsule Substances 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 229960003067 cystine Drugs 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- 229960000304 folic acid Drugs 0.000 claims description 2
- 235000019152 folic acid Nutrition 0.000 claims description 2
- 239000011724 folic acid Substances 0.000 claims description 2
- 229960000367 inositol Drugs 0.000 claims description 2
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 claims description 2
- 239000006210 lotion Substances 0.000 claims description 2
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- 229940055726 pantothenic acid Drugs 0.000 claims description 2
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- 239000002904 solvent Substances 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 235000019156 vitamin B Nutrition 0.000 claims description 2
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- 241000208340 Araliaceae Species 0.000 claims 1
- 244000268590 Euryale ferox Species 0.000 claims 1
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- 241000628997 Flos Species 0.000 claims 1
- 241000222336 Ganoderma Species 0.000 claims 1
- 102000011782 Keratins Human genes 0.000 claims 1
- 108010076876 Keratins Proteins 0.000 claims 1
- 241000168720 Panax japonicus Species 0.000 claims 1
- 235000003174 Panax japonicus Nutrition 0.000 claims 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims 1
- 235000003140 Panax quinquefolius Nutrition 0.000 claims 1
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 235000008434 ginseng Nutrition 0.000 claims 1
- 235000013372 meat Nutrition 0.000 claims 1
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims 1
- 230000000638 stimulation Effects 0.000 claims 1
- 210000004761 scalp Anatomy 0.000 abstract description 6
- 210000004209 hair Anatomy 0.000 abstract description 5
- 230000000694 effects Effects 0.000 description 10
- 230000028327 secretion Effects 0.000 description 7
- 235000019197 fats Nutrition 0.000 description 4
- 210000002374 sebum Anatomy 0.000 description 4
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- 230000002588 toxic effect Effects 0.000 description 4
- 208000002874 Acne Vulgaris Diseases 0.000 description 3
- 206010000496 acne Diseases 0.000 description 3
- 208000004631 alopecia areata Diseases 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 2
- VRSMJNVXOITYPE-FSDIUQKZSA-N ethyl 4-[[(2e,4e,6e,8e)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoyl]amino]benzoate Chemical compound C1=CC(C(=O)OCC)=CC=C1NC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VRSMJNVXOITYPE-FSDIUQKZSA-N 0.000 description 2
- 210000003780 hair follicle Anatomy 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 210000003491 skin Anatomy 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 206010048768 Dermatosis Diseases 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 description 1
- 239000003098 androgen Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
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- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to use vitamin A and derivant thereof and hair growth is formed the prescription for the treatment of seborrheic alopecia by the Chinese medicine and western medicine that stimulates facilitation.This prescription can suppress excessive undesired the overflowing of scalp fat effectively, so can prevent seborrheic alopecia effectively, promotes hair replacement, is a kind of prescription of effectively treatment seborrheic alopecia.
Description
The present invention relates to use vitamin A and derivant thereof and hair growth is formed the prescription for the treatment of seborrheic alopecia by the medicine that stimulates facilitation.
Alopecia is a kind of dermatosis of common pilosity, mainly is divided into two types, and promptly non-seborrheic alopecia such as alopecia areata and seborrheic alopecia are so-called male pattern alopecia.The symptom of these two kinds of alopecias is different, alopecia areata patient often in several days hair fallen of copper coin size suddenly, the hair at other positions is excellent, patient men and women, old and young have, alopecia areata sometimes can spontaneous recovery.The patient of seborrheic alopecia is mainly young and middle-aged male, patient's scalp fat excessive secretion, the many bits of scalp humidity be a kind of diffusivity gradation can not spontaneous recovery permanent alopecia.The sickness rate of seborrheic alopecia we can say that than high of non-seborrheic alopecia general common alopecia all is seborrheic alopecia mostly more.The essential cause of disease of seborrheic alopecia it be not immediately clear, it is generally acknowledged may with androgen secretion cross prosperous relevant because few people suffer from seborrheic alopecia among the women.But its immediate cause still is more clearly, and it is relevant with the excessive secretion of sebum.To the toxic effect of hair follicle, cause hair to be poisoned when sebum and wherein contained some chemical analysis such as Squalene, oleic acid and linoleic acid etc. are excessive, withered, come off.
Seborrheic alopecia is a great problem of current dermatology, at present in the world also not to the real effectively medicine of treatment seborrheic alopecia, though the medicine of some treatment alopecias is also arranged on the market, but this class drug main is effective to non-seborrheic alopecia, invalid substantially or curative effect is very little to seborrheic alopecia, overflow because these medicines all can not suppress the excessive of scalp fat effectively, thereby can't stop further coming off of hair.Therefore, a kind of excessive secretion that at first should want to suppress effectively or to reduce scalp fat to the real effectively medicine of treatment seborrheic alopecia.
Vitamin A and derivant thereof have the function that suppresses sebum secretion, and this is confirmed by a large amount of clinical experiments
[1]Just there was the human vitamin A to treat acne (acne also is to be caused by face's sebum excessive secretion) from 50 years, obtains curative effect preferably.In recent decades, people take the toxic and side effects that vitamin A causes in a large number in order to reduce, synthetic the derivant of hundreds of kind vitamin A, and therefrom screened some toxic and side effects lower treat acne, more existing at present medicine appearances preferably obtain satisfied curative effect.
On the other hand, there are many medicines that hair growth is had facilitation in the Chinese medicine, as Radix Polygoni Multiflori, Radix Angelicae Sinensis, Radix Codonopsis, the Radix Astragali, Radix Rehmanniae Preparata, Semen Cuscutae, Fructus Psoraleae, Radix Achyranthis Bidentatae, Semen Sesami Nigrum etc., cystine in the Western medicine, inositol, folic acid, pantothenic acid, vitamin B etc. promote that also to safeguarding the skin normal function hair growth has good effect.The effect for the treatment of non-seborrheic alopecia with the prescription of this class medicine composition is tangible.But it is only also bad to treatment seborrheic alopecia effect with the prescription of this class medicine composition.Do not see as yet with vitamin A and derivant thereof at present yet and cooperate the report for the treatment of seborrheic alopecia with Chinese medicine.
The prescription that the present invention relates to be traditional hair growth is had add vitamin A and derivant thereof in the Chinese medicine and western medicine that stimulates facilitation as selecting the less Viaminate of toxic and side effects [N-(4-carbethoxy phenyl) VAAE)] for use
[2]Come prescription.New prescription can suppress the excessive secretion of scalp fat effectively, thus can prevent effectively old continue come off, can swash the regeneration that thorn promotes New Development simultaneously again, thereby reach curative effect preferably.Clinical experiment shows, take this medicine after one week the degree of alopecia just can reduce greatly, more New Development germinating just arranged in one month and grow fine.As long as hair follicle is not downright bad fully as yet, in 3~5 months most alopecia is grown, the patient can recover original appearance substantially.
This prescription can have oral and be coated with two kinds of forms outward.Adopt the suitable pharmaceutical carrier excipient, can be made into suitable oral agents, as tablet, capsule, powder, unguentum, electuary, oral liquid etc., wherein the oral dose of vitamin A and derivant thereof is per kilogram of body weight 0.03mg to 3mg every day.Can make lotion with suitable solvent, wherein the concentration of vitamin A and derivant thereof is not less than 0.005%.
The best prescription of implementing:
Radix Codonopsis 50 restrains, Radix Angelicae Sinensis 50 restrains, the Radix Astragali 50 restrains, Radix Polygoni Multiflori 50 restrains, Rhizoma Drynariae 40 restrains, Radix Rehmanniae Preparata 40 restrains,
Semen Cuscutae 30 grams, Radix Achyranthis Bidentatae 30 grams, Semen Sesami Nigrum 30 grams, Rhizoma Polygonati 27 grams, viaminate 3 grams
Above medicine is made powder add appropriate excipients, be processed into coated tablet.Everyone every day, oral 4 grams were taken at twice.
List of references
[1] Kligman A.M., foreign medical science (skin), 1:33~34,1982
[2] Du Cong etc., Acta Pharmaceutica Sinica, 17(5): 331-335,1982
Xie Jinghui, clinical department of dermatologry magazine, 6:304-305,1985
Yu Ruiyao, new drug and clinical, 5(1): 27-29,1986
Claims (4)
1, a kind of prescription for the treatment of seborrheic alopecia, this prescription by vitamin A and derivant thereof with a kind of and more than one hair growth is made up of the medicine of stimulation facilitation.
2, hair growth is had in the claim 1 stimulates the medicine of facilitation to refer to: Radix Ginseng, the Radix Rehmanniae, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Radix Codonopsis, Radix Polygoni Multiflori, Radix Acanthopanacis Senticosi, Radix Et Caulis Acanthopanacis Senticosi, the Radix Astragali, the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae, Herba Ecliptae, Semen Cuscutae, Radix Glycyrrhizae, Rhizoma Polygonati, Radix Achyranthis Bidentatae, Herba Epimedii, Fructus Psoraleae, Rhizoma Drynariae, work as medicine, panax japonicus, Fructus Corni, Radix Ophiopogonis, the Cortex Eucommiae, Radix Morindae Officinalis, Rhizoma Cimicifugae, Semen Euryales, Fructus Rubi, Rhizoma Dioscoreae, the Wood-scoop Fructus Lycii, Cortex Cinnamomi, Fructus Ligustri Lucidi, the Radix Asparagi door, Semen Sesami, semen juglandis, Lac regis apis, Ganoderma, Fructus Chaenomelis, Rhizoma Et Radix Notopterygii, Semen Coicis, Rhizoma Gastrodiae, Cortex Dictamni, the Fructus Kochiae, Fructus rhois chinensis, Herba Leonuri, Poria, Radix Salviae Miltiorrhizae, Flos Carthami, Radix Bupleuri, Radix Paeoniae Rubra, Cacumen Platycladi, the Radix Angelicae Dahuricae, Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, RADIX CURCUMAE, the meat desert holds, cystine, keratin, inositol, folic acid, pantothenic acid, vitamin B.
3, the formed prescription of claim 1 and claim 2, also can be during as oral agents with suitable pharmaceutical carrier, excipient, make and be fit to oral medicament, as tablet, capsule, powder, unguentum, electuary, wherein the consumption of vitamin A and derivant thereof is per kilogram of body weight 0.03mg to 3mg every day.
4, the prescription of claim 1 and claim 2 formation can also be made lotion with suitable solvent, and wherein the concentration of vitamin A and derivant thereof is not less than 0.005%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92113387 CN1087267A (en) | 1992-11-23 | 1992-11-23 | A kind of prescription for the treatment of seborrheic alopecia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92113387 CN1087267A (en) | 1992-11-23 | 1992-11-23 | A kind of prescription for the treatment of seborrheic alopecia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1087267A true CN1087267A (en) | 1994-06-01 |
Family
ID=4946380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 92113387 Pending CN1087267A (en) | 1992-11-23 | 1992-11-23 | A kind of prescription for the treatment of seborrheic alopecia |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1087267A (en) |
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998006412A1 (en) * | 1996-08-09 | 1998-02-19 | Xiaochun Mei | A medicine of external use for treating seborrheic baldness with high efficacy and low side effect and preparation thereof |
| CN1051466C (en) * | 1995-04-18 | 2000-04-19 | 梅晓春 | External medicine for treating seborrheic alopecia |
| CN1051464C (en) * | 1994-04-14 | 2000-04-19 | 梅晓春 | Oral medicine for curing seborrheic baldness |
| CN1051465C (en) * | 1995-04-11 | 2000-04-19 | 梅晓春 | External use medicine for seborrheic alopecia |
| CN1301745C (en) * | 2004-11-26 | 2007-02-28 | 付小珍 | Chinese medicinal liquid for treating alopecia and its production method |
| CN101164565B (en) * | 2006-10-18 | 2011-01-12 | 武彪 | Quick-effective traditional Chinese medicine for treating beard and hair small and white, early white and alopecia in aged |
| CN102166179A (en) * | 2010-11-29 | 2011-08-31 | 吴克 | Self-straightening hair cream |
| CN102178856A (en) * | 2011-04-26 | 2011-09-14 | 林佳 | Hair restorer |
| CN102885986A (en) * | 2012-11-07 | 2013-01-23 | 桂林理工大学 | Formula and preparation method of traditional Chinese medicine for treating alopecia |
| CN102908489A (en) * | 2012-10-31 | 2013-02-06 | 李玉宾 | Traditional Chinese medicine composition for treating seborrheic alopecia and preparation method of same |
| CN102908508A (en) * | 2012-10-31 | 2013-02-06 | 李玉宾 | Medicinal composition for treating seborrheic alopecia and preparation method thereof |
| CN105816677A (en) * | 2016-05-10 | 2016-08-03 | 郑植 | Traditional Chinese medicine for treating alopecia |
| CN105920170A (en) * | 2016-05-27 | 2016-09-07 | 廖鲜芳 | Traditional herba preparation preventing hair loss |
| CN105943917A (en) * | 2016-06-24 | 2016-09-21 | 安徽省丰康农业科技有限公司 | Royal jelly hair care cream capable of promoting hair growth and preparation method thereof |
| CN106109715A (en) * | 2016-08-31 | 2016-11-16 | 王志军 | A kind of medicine of hair growth and preparation method thereof |
| WO2018032838A1 (en) * | 2016-08-13 | 2018-02-22 | 谭华锋 | Traditional chinese medicine enzyme for equilibrating male 5α-reductase |
| CN110538267A (en) * | 2018-05-28 | 2019-12-06 | 南京青丝永盛生物科技有限公司 | Traditional Chinese medicine composition with remarkable alopecia prevention effect and preparation method thereof |
| CN110604784A (en) * | 2018-05-28 | 2019-12-24 | 南京青丝永盛生物科技有限公司 | Traditional Chinese medicine composition with remarkable alopecia prevention effect and application of traditional Chinese medicine composition in hair growth |
| CN117253536A (en) * | 2023-08-31 | 2023-12-19 | 南方医科大学中西医结合医院 | Traditional Chinese medicine composition for treating alopecia as well as screening method, preparation method and application thereof |
-
1992
- 1992-11-23 CN CN 92113387 patent/CN1087267A/en active Pending
Cited By (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1051464C (en) * | 1994-04-14 | 2000-04-19 | 梅晓春 | Oral medicine for curing seborrheic baldness |
| CN1051465C (en) * | 1995-04-11 | 2000-04-19 | 梅晓春 | External use medicine for seborrheic alopecia |
| CN1051466C (en) * | 1995-04-18 | 2000-04-19 | 梅晓春 | External medicine for treating seborrheic alopecia |
| WO1998006412A1 (en) * | 1996-08-09 | 1998-02-19 | Xiaochun Mei | A medicine of external use for treating seborrheic baldness with high efficacy and low side effect and preparation thereof |
| CN1301745C (en) * | 2004-11-26 | 2007-02-28 | 付小珍 | Chinese medicinal liquid for treating alopecia and its production method |
| CN101164565B (en) * | 2006-10-18 | 2011-01-12 | 武彪 | Quick-effective traditional Chinese medicine for treating beard and hair small and white, early white and alopecia in aged |
| CN102166179A (en) * | 2010-11-29 | 2011-08-31 | 吴克 | Self-straightening hair cream |
| CN102178856A (en) * | 2011-04-26 | 2011-09-14 | 林佳 | Hair restorer |
| CN102178856B (en) * | 2011-04-26 | 2015-09-09 | 林佳 | A kind of hair growth promoter |
| CN102908508A (en) * | 2012-10-31 | 2013-02-06 | 李玉宾 | Medicinal composition for treating seborrheic alopecia and preparation method thereof |
| CN102908489A (en) * | 2012-10-31 | 2013-02-06 | 李玉宾 | Traditional Chinese medicine composition for treating seborrheic alopecia and preparation method of same |
| CN102908508B (en) * | 2012-10-31 | 2014-12-03 | 王政乾 | Medicinal composition for treating seborrheic alopecia and preparation method thereof |
| CN102885986A (en) * | 2012-11-07 | 2013-01-23 | 桂林理工大学 | Formula and preparation method of traditional Chinese medicine for treating alopecia |
| CN105816677A (en) * | 2016-05-10 | 2016-08-03 | 郑植 | Traditional Chinese medicine for treating alopecia |
| CN105920170A (en) * | 2016-05-27 | 2016-09-07 | 廖鲜芳 | Traditional herba preparation preventing hair loss |
| CN105943917A (en) * | 2016-06-24 | 2016-09-21 | 安徽省丰康农业科技有限公司 | Royal jelly hair care cream capable of promoting hair growth and preparation method thereof |
| WO2018032838A1 (en) * | 2016-08-13 | 2018-02-22 | 谭华锋 | Traditional chinese medicine enzyme for equilibrating male 5α-reductase |
| CN106109715A (en) * | 2016-08-31 | 2016-11-16 | 王志军 | A kind of medicine of hair growth and preparation method thereof |
| CN110538267A (en) * | 2018-05-28 | 2019-12-06 | 南京青丝永盛生物科技有限公司 | Traditional Chinese medicine composition with remarkable alopecia prevention effect and preparation method thereof |
| CN110604784A (en) * | 2018-05-28 | 2019-12-24 | 南京青丝永盛生物科技有限公司 | Traditional Chinese medicine composition with remarkable alopecia prevention effect and application of traditional Chinese medicine composition in hair growth |
| CN117253536A (en) * | 2023-08-31 | 2023-12-19 | 南方医科大学中西医结合医院 | Traditional Chinese medicine composition for treating alopecia as well as screening method, preparation method and application thereof |
| CN117253536B (en) * | 2023-08-31 | 2025-02-11 | 南方医科大学中西医结合医院 | Traditional Chinese medicine composition for treating hair loss and screening method, preparation method and application thereof |
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