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CN1087267A - A kind of prescription for the treatment of seborrheic alopecia - Google Patents

A kind of prescription for the treatment of seborrheic alopecia Download PDF

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Publication number
CN1087267A
CN1087267A CN 92113387 CN92113387A CN1087267A CN 1087267 A CN1087267 A CN 1087267A CN 92113387 CN92113387 CN 92113387 CN 92113387 A CN92113387 A CN 92113387A CN 1087267 A CN1087267 A CN 1087267A
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China
Prior art keywords
radix
prescription
rhizoma
fructus
vitamin
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CN 92113387
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Chinese (zh)
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梅晓春
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Individual
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Individual
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Priority to CN 92113387 priority Critical patent/CN1087267A/en
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Abstract

The present invention relates to use vitamin A and derivant thereof and hair growth is formed the prescription for the treatment of seborrheic alopecia by the Chinese medicine and western medicine that stimulates facilitation.This prescription can suppress excessive undesired the overflowing of scalp fat effectively, so can prevent seborrheic alopecia effectively, promotes hair replacement, is a kind of prescription of effectively treatment seborrheic alopecia.

Description

A kind of prescription for the treatment of seborrheic alopecia
The present invention relates to use vitamin A and derivant thereof and hair growth is formed the prescription for the treatment of seborrheic alopecia by the medicine that stimulates facilitation.
Alopecia is a kind of dermatosis of common pilosity, mainly is divided into two types, and promptly non-seborrheic alopecia such as alopecia areata and seborrheic alopecia are so-called male pattern alopecia.The symptom of these two kinds of alopecias is different, alopecia areata patient often in several days hair fallen of copper coin size suddenly, the hair at other positions is excellent, patient men and women, old and young have, alopecia areata sometimes can spontaneous recovery.The patient of seborrheic alopecia is mainly young and middle-aged male, patient's scalp fat excessive secretion, the many bits of scalp humidity be a kind of diffusivity gradation can not spontaneous recovery permanent alopecia.The sickness rate of seborrheic alopecia we can say that than high of non-seborrheic alopecia general common alopecia all is seborrheic alopecia mostly more.The essential cause of disease of seborrheic alopecia it be not immediately clear, it is generally acknowledged may with androgen secretion cross prosperous relevant because few people suffer from seborrheic alopecia among the women.But its immediate cause still is more clearly, and it is relevant with the excessive secretion of sebum.To the toxic effect of hair follicle, cause hair to be poisoned when sebum and wherein contained some chemical analysis such as Squalene, oleic acid and linoleic acid etc. are excessive, withered, come off.
Seborrheic alopecia is a great problem of current dermatology, at present in the world also not to the real effectively medicine of treatment seborrheic alopecia, though the medicine of some treatment alopecias is also arranged on the market, but this class drug main is effective to non-seborrheic alopecia, invalid substantially or curative effect is very little to seborrheic alopecia, overflow because these medicines all can not suppress the excessive of scalp fat effectively, thereby can't stop further coming off of hair.Therefore, a kind of excessive secretion that at first should want to suppress effectively or to reduce scalp fat to the real effectively medicine of treatment seborrheic alopecia.
Vitamin A and derivant thereof have the function that suppresses sebum secretion, and this is confirmed by a large amount of clinical experiments [1]Just there was the human vitamin A to treat acne (acne also is to be caused by face's sebum excessive secretion) from 50 years, obtains curative effect preferably.In recent decades, people take the toxic and side effects that vitamin A causes in a large number in order to reduce, synthetic the derivant of hundreds of kind vitamin A, and therefrom screened some toxic and side effects lower treat acne, more existing at present medicine appearances preferably obtain satisfied curative effect.
On the other hand, there are many medicines that hair growth is had facilitation in the Chinese medicine, as Radix Polygoni Multiflori, Radix Angelicae Sinensis, Radix Codonopsis, the Radix Astragali, Radix Rehmanniae Preparata, Semen Cuscutae, Fructus Psoraleae, Radix Achyranthis Bidentatae, Semen Sesami Nigrum etc., cystine in the Western medicine, inositol, folic acid, pantothenic acid, vitamin B etc. promote that also to safeguarding the skin normal function hair growth has good effect.The effect for the treatment of non-seborrheic alopecia with the prescription of this class medicine composition is tangible.But it is only also bad to treatment seborrheic alopecia effect with the prescription of this class medicine composition.Do not see as yet with vitamin A and derivant thereof at present yet and cooperate the report for the treatment of seborrheic alopecia with Chinese medicine.
The prescription that the present invention relates to be traditional hair growth is had add vitamin A and derivant thereof in the Chinese medicine and western medicine that stimulates facilitation as selecting the less Viaminate of toxic and side effects [N-(4-carbethoxy phenyl) VAAE)] for use [2]Come prescription.New prescription can suppress the excessive secretion of scalp fat effectively, thus can prevent effectively old continue come off, can swash the regeneration that thorn promotes New Development simultaneously again, thereby reach curative effect preferably.Clinical experiment shows, take this medicine after one week the degree of alopecia just can reduce greatly, more New Development germinating just arranged in one month and grow fine.As long as hair follicle is not downright bad fully as yet, in 3~5 months most alopecia is grown, the patient can recover original appearance substantially.
This prescription can have oral and be coated with two kinds of forms outward.Adopt the suitable pharmaceutical carrier excipient, can be made into suitable oral agents, as tablet, capsule, powder, unguentum, electuary, oral liquid etc., wherein the oral dose of vitamin A and derivant thereof is per kilogram of body weight 0.03mg to 3mg every day.Can make lotion with suitable solvent, wherein the concentration of vitamin A and derivant thereof is not less than 0.005%.
The best prescription of implementing:
Radix Codonopsis 50 restrains, Radix Angelicae Sinensis 50 restrains, the Radix Astragali 50 restrains, Radix Polygoni Multiflori 50 restrains, Rhizoma Drynariae 40 restrains, Radix Rehmanniae Preparata 40 restrains,
Semen Cuscutae 30 grams, Radix Achyranthis Bidentatae 30 grams, Semen Sesami Nigrum 30 grams, Rhizoma Polygonati 27 grams, viaminate 3 grams
Above medicine is made powder add appropriate excipients, be processed into coated tablet.Everyone every day, oral 4 grams were taken at twice.
List of references
[1] Kligman A.M., foreign medical science (skin), 1:33~34,1982
[2] Du Cong etc., Acta Pharmaceutica Sinica, 17(5): 331-335,1982
Xie Jinghui, clinical department of dermatologry magazine, 6:304-305,1985
Yu Ruiyao, new drug and clinical, 5(1): 27-29,1986

Claims (4)

1, a kind of prescription for the treatment of seborrheic alopecia, this prescription by vitamin A and derivant thereof with a kind of and more than one hair growth is made up of the medicine of stimulation facilitation.
2, hair growth is had in the claim 1 stimulates the medicine of facilitation to refer to: Radix Ginseng, the Radix Rehmanniae, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Radix Codonopsis, Radix Polygoni Multiflori, Radix Acanthopanacis Senticosi, Radix Et Caulis Acanthopanacis Senticosi, the Radix Astragali, the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae, Herba Ecliptae, Semen Cuscutae, Radix Glycyrrhizae, Rhizoma Polygonati, Radix Achyranthis Bidentatae, Herba Epimedii, Fructus Psoraleae, Rhizoma Drynariae, work as medicine, panax japonicus, Fructus Corni, Radix Ophiopogonis, the Cortex Eucommiae, Radix Morindae Officinalis, Rhizoma Cimicifugae, Semen Euryales, Fructus Rubi, Rhizoma Dioscoreae, the Wood-scoop Fructus Lycii, Cortex Cinnamomi, Fructus Ligustri Lucidi, the Radix Asparagi door, Semen Sesami, semen juglandis, Lac regis apis, Ganoderma, Fructus Chaenomelis, Rhizoma Et Radix Notopterygii, Semen Coicis, Rhizoma Gastrodiae, Cortex Dictamni, the Fructus Kochiae, Fructus rhois chinensis, Herba Leonuri, Poria, Radix Salviae Miltiorrhizae, Flos Carthami, Radix Bupleuri, Radix Paeoniae Rubra, Cacumen Platycladi, the Radix Angelicae Dahuricae, Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, RADIX CURCUMAE, the meat desert holds, cystine, keratin, inositol, folic acid, pantothenic acid, vitamin B.
3, the formed prescription of claim 1 and claim 2, also can be during as oral agents with suitable pharmaceutical carrier, excipient, make and be fit to oral medicament, as tablet, capsule, powder, unguentum, electuary, wherein the consumption of vitamin A and derivant thereof is per kilogram of body weight 0.03mg to 3mg every day.
4, the prescription of claim 1 and claim 2 formation can also be made lotion with suitable solvent, and wherein the concentration of vitamin A and derivant thereof is not less than 0.005%.
CN 92113387 1992-11-23 1992-11-23 A kind of prescription for the treatment of seborrheic alopecia Pending CN1087267A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 92113387 CN1087267A (en) 1992-11-23 1992-11-23 A kind of prescription for the treatment of seborrheic alopecia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 92113387 CN1087267A (en) 1992-11-23 1992-11-23 A kind of prescription for the treatment of seborrheic alopecia

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CN1087267A true CN1087267A (en) 1994-06-01

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Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998006412A1 (en) * 1996-08-09 1998-02-19 Xiaochun Mei A medicine of external use for treating seborrheic baldness with high efficacy and low side effect and preparation thereof
CN1051466C (en) * 1995-04-18 2000-04-19 梅晓春 External medicine for treating seborrheic alopecia
CN1051464C (en) * 1994-04-14 2000-04-19 梅晓春 Oral medicine for curing seborrheic baldness
CN1051465C (en) * 1995-04-11 2000-04-19 梅晓春 External use medicine for seborrheic alopecia
CN1301745C (en) * 2004-11-26 2007-02-28 付小珍 Chinese medicinal liquid for treating alopecia and its production method
CN101164565B (en) * 2006-10-18 2011-01-12 武彪 Quick-effective traditional Chinese medicine for treating beard and hair small and white, early white and alopecia in aged
CN102166179A (en) * 2010-11-29 2011-08-31 吴克 Self-straightening hair cream
CN102178856A (en) * 2011-04-26 2011-09-14 林佳 Hair restorer
CN102885986A (en) * 2012-11-07 2013-01-23 桂林理工大学 Formula and preparation method of traditional Chinese medicine for treating alopecia
CN102908489A (en) * 2012-10-31 2013-02-06 李玉宾 Traditional Chinese medicine composition for treating seborrheic alopecia and preparation method of same
CN102908508A (en) * 2012-10-31 2013-02-06 李玉宾 Medicinal composition for treating seborrheic alopecia and preparation method thereof
CN105816677A (en) * 2016-05-10 2016-08-03 郑植 Traditional Chinese medicine for treating alopecia
CN105920170A (en) * 2016-05-27 2016-09-07 廖鲜芳 Traditional herba preparation preventing hair loss
CN105943917A (en) * 2016-06-24 2016-09-21 安徽省丰康农业科技有限公司 Royal jelly hair care cream capable of promoting hair growth and preparation method thereof
CN106109715A (en) * 2016-08-31 2016-11-16 王志军 A kind of medicine of hair growth and preparation method thereof
WO2018032838A1 (en) * 2016-08-13 2018-02-22 谭华锋 Traditional chinese medicine enzyme for equilibrating male 5α-reductase
CN110538267A (en) * 2018-05-28 2019-12-06 南京青丝永盛生物科技有限公司 Traditional Chinese medicine composition with remarkable alopecia prevention effect and preparation method thereof
CN110604784A (en) * 2018-05-28 2019-12-24 南京青丝永盛生物科技有限公司 Traditional Chinese medicine composition with remarkable alopecia prevention effect and application of traditional Chinese medicine composition in hair growth
CN117253536A (en) * 2023-08-31 2023-12-19 南方医科大学中西医结合医院 Traditional Chinese medicine composition for treating alopecia as well as screening method, preparation method and application thereof

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1051464C (en) * 1994-04-14 2000-04-19 梅晓春 Oral medicine for curing seborrheic baldness
CN1051465C (en) * 1995-04-11 2000-04-19 梅晓春 External use medicine for seborrheic alopecia
CN1051466C (en) * 1995-04-18 2000-04-19 梅晓春 External medicine for treating seborrheic alopecia
WO1998006412A1 (en) * 1996-08-09 1998-02-19 Xiaochun Mei A medicine of external use for treating seborrheic baldness with high efficacy and low side effect and preparation thereof
CN1301745C (en) * 2004-11-26 2007-02-28 付小珍 Chinese medicinal liquid for treating alopecia and its production method
CN101164565B (en) * 2006-10-18 2011-01-12 武彪 Quick-effective traditional Chinese medicine for treating beard and hair small and white, early white and alopecia in aged
CN102166179A (en) * 2010-11-29 2011-08-31 吴克 Self-straightening hair cream
CN102178856A (en) * 2011-04-26 2011-09-14 林佳 Hair restorer
CN102178856B (en) * 2011-04-26 2015-09-09 林佳 A kind of hair growth promoter
CN102908508A (en) * 2012-10-31 2013-02-06 李玉宾 Medicinal composition for treating seborrheic alopecia and preparation method thereof
CN102908489A (en) * 2012-10-31 2013-02-06 李玉宾 Traditional Chinese medicine composition for treating seborrheic alopecia and preparation method of same
CN102908508B (en) * 2012-10-31 2014-12-03 王政乾 Medicinal composition for treating seborrheic alopecia and preparation method thereof
CN102885986A (en) * 2012-11-07 2013-01-23 桂林理工大学 Formula and preparation method of traditional Chinese medicine for treating alopecia
CN105816677A (en) * 2016-05-10 2016-08-03 郑植 Traditional Chinese medicine for treating alopecia
CN105920170A (en) * 2016-05-27 2016-09-07 廖鲜芳 Traditional herba preparation preventing hair loss
CN105943917A (en) * 2016-06-24 2016-09-21 安徽省丰康农业科技有限公司 Royal jelly hair care cream capable of promoting hair growth and preparation method thereof
WO2018032838A1 (en) * 2016-08-13 2018-02-22 谭华锋 Traditional chinese medicine enzyme for equilibrating male 5α-reductase
CN106109715A (en) * 2016-08-31 2016-11-16 王志军 A kind of medicine of hair growth and preparation method thereof
CN110538267A (en) * 2018-05-28 2019-12-06 南京青丝永盛生物科技有限公司 Traditional Chinese medicine composition with remarkable alopecia prevention effect and preparation method thereof
CN110604784A (en) * 2018-05-28 2019-12-24 南京青丝永盛生物科技有限公司 Traditional Chinese medicine composition with remarkable alopecia prevention effect and application of traditional Chinese medicine composition in hair growth
CN117253536A (en) * 2023-08-31 2023-12-19 南方医科大学中西医结合医院 Traditional Chinese medicine composition for treating alopecia as well as screening method, preparation method and application thereof
CN117253536B (en) * 2023-08-31 2025-02-11 南方医科大学中西医结合医院 Traditional Chinese medicine composition for treating hair loss and screening method, preparation method and application thereof

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