CN108175814A - A kind of powder for treating baby diarrhea and preparation method thereof - Google Patents
A kind of powder for treating baby diarrhea and preparation method thereof Download PDFInfo
- Publication number
- CN108175814A CN108175814A CN201711478589.6A CN201711478589A CN108175814A CN 108175814 A CN108175814 A CN 108175814A CN 201711478589 A CN201711478589 A CN 201711478589A CN 108175814 A CN108175814 A CN 108175814A
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- powder
- composition
- root
- asarum
- borneol
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Abstract
The present invention discloses a kind of powder for treating baby diarrhea, is made of component as follows according to the mass fraction：Patchouli 40 90, Radix Glycyrrhizae 20 60, Rhizoma Chuanxiong 40 90, borneol 36, grass-leaved sweetflag 40 90, cloves 40 90, Radix Aucklandiae 40 90, dried orange peel 40 90, Lysimachia foenum-graecum 40 90, agalloch eaglewood 40 90, rhizoma atractylodis 40 90, Chinese cassia tree 40 90, menthol 15, the root of Dahurain angelica 20 40, peppermint 5 10, asarum 20 40, Cortex Magnoliae Officinalis 40 90 form.And raw material is taken successively, it discharges after preparing completely.Effectively treatment children's diarrhoea abdomen twists, the diseases such as collywobbles abdominal distension.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of powder for treating baby diarrhea and preparation method thereof.
Background technology
At present, it is although various for treating the medicament categories of baby diarrhea, it is clinical without safely and effectively specific drug
Applied chemistry drug therapy is more universal, and drug is mostly based on antibiotic, anti-inflammatory, but the side effect of clinical application is big, dangerous
It is higher, with other medicines drug combination, the clinical application risk of child patient is more increased, therefore, exploitation is safely and effectively controlled
The drug for treating baby diarrhea has preferable Social benefit and economic benefit.
Invention content
It is insufficient present in existing treatment baby diarrhea drug it is an object of the invention to be directed to, it provides a kind of with treatment
The drug powder of baby diarrhea effect.
Another object of the present invention is to provide the preparation method of aforementioned pharmaceutical compositions, this method is easy to operate, is convenient for
Implement, drug recovery rate is high, has been maximally maintained the active ingredient of drug.
The object of the invention is achieved by following scheme：
The treatment baby diarrhea powder of the present invention, is made of component as follows according to the mass fraction：
Patchouli 40-90, Radix Glycyrrhizae 20-60, Rhizoma Chuanxiong 40-90, borneol 3-6, grass-leaved sweetflag 40-90, cloves 40-90, Radix Aucklandiae 40-90,
Dried orange peel 40-90, Lysimachia foenum-graecum 40-90, agalloch eaglewood 40-90, rhizoma atractylodis 40-90, Chinese cassia tree 40-90, menthol 1-5, root of Dahurain angelica 20-40, peppermint
5-10, asarum 20-40, Cortex Magnoliae Officinalis 40-90 compositions.
Wherein, the composition is preferably made of component as follows according to the mass fraction：
Patchouli 60-80, Radix Glycyrrhizae 40-50, Rhizoma Chuanxiong 60-80, borneol 4-5, grass-leaved sweetflag 60-80, cloves 60-80, Radix Aucklandiae 60-80,
Dried orange peel 60-80, Lysimachia foenum-graecum 60-80, agalloch eaglewood 60-80, rhizoma atractylodis 60-80, Chinese cassia tree 60-80, menthol 3-4, root of Dahurain angelica 25-30, peppermint
7-9, asarum 25-30, Cortex Magnoliae Officinalis 60-80 compositions.
The composition is most preferably to be made of component as follows according to the mass fraction：
Patchouli 70, Radix Glycyrrhizae 45, Rhizoma Chuanxiong 70, borneol 4, grass-leaved sweetflag 70, cloves 70, Radix Aucklandiae 70, dried orange peel 70, Lysimachia foenum-graecum 70, agalloch eaglewood
70th, rhizoma atractylodis 70, Chinese cassia tree 70, menthol 3, the root of Dahurain angelica 25, peppermint 7, asarum 25, Cortex Magnoliae Officinalis 70 form.
Pogostemon cablin (Pogostemon cablin)：Labiate, perennial herb upright plant are aromatic.Originate in phenanthrene
Lv Bin, the cultivation of Southeast Asia various regions is more, and also there are a large amount of cultivations in southern area of China.Herb contains volatile oil, can be used as strong stimulation medicine
It is perfume common composition with fragrant material.The major function of Pogostemon cablin mainly remove dampness by means of aromatics, anti-vomiting, driving away summer heat inducing diaphoresis.Master is wet
Gastral cavity abdomen ruffian Min of coke in resistance, loss of appetite, vomiting, diarrhea, the fever and chills headache of diseases caused by external factors summer-heat and damp, damp-warm syndrome from the beginning of fever body be stranded, chest
Min nausea, nasosinusitis, tinea of feet and hands.
Radix Glycyrrhizae：Radix Glycyrrhizae（Scientific name：Glycyrrhiza uralensis Fisch）Alias：State is old, Herba Hedyotis cantonensis, Glycyrrhiza Uralensis,
Sweet tea root.Pulse family, Glycyrrhiza perennial herb, root is sturdy with root-like stock, is a kind of help Chinese herbal medicine.It is a kind of well to human body
Medicine, medicinal part are root and rhizomes, and Medicinal Materials Characters root is cylinder, 25-100 centimetres long, 0.6-3.5 centimetres of diameter.Crust pine
Tightly differ, surface rufous or taupe brown.Rhizome is cylinder, and there is bud scar on surface, has marrow in the middle part of section.Happiness is dark moist, day
According to the low dry climate of long temperature.Radix Glycyrrhizae with being grown in arid, semiarid desert steppe, desert edge and loess hill more
Band.Radix Glycyrrhizae major function is for the heart qi deficiency, palpitation and severe palpitation, intermittent pulse and deficiency of spleen-QI and stomach-QI, lassitude hypodynamia, ulcer sores, throat
Swelling and pain, for reconciling the strong of some drugs.
Rhizoma Chuanxiong：It is samphire Rhizoma Chuanxiong（Ligusticum chuanxiong）Dry rhizome.Universal umbel, plumage
Shape compound leaf, herbaceos perennial.Summer harvests when the section disk significant projections on stem during purplish, silt is removed, after solarization
A heatable brick bed is done, then removes fibrous root.Drug first choice for the treatment of headache.It cures mainly：The stagnant raw meat pain of irregular menstruation, closed dysmenorrhea, the postpartum stasis of blood, abdominal mass swell
Block, pain in chest and hypochondrium, dizziness of having a headache, wind-cold-dampness arthralgia, traumatic injury, ulcer sores etc..
Borneol：Borneol also known as piece brain, orange slices, kapur, MEIHUA BINGPIAN, Dipterocarpus pilosus, plum blossom brain, borneol brain, Mei Bing
Deng, be Spore density kapur resin and volatile oil processed goods extraction obtain crystallization, be near pure dextrorotation
Borneol.Also it is useful to be chemically synthesized.It cures mainly：Lead to all keys, dissipate stagnated fire, remove screen improving eyesight, swelling and pain relieving.Control apoplexy lockjaw, pyreticosis
Coma, frightened epilepsy phlegm confusing heart, deafness with qi stagnation, larynx numbness, aphtha, tympanitis, carbuncle swells, hemorrhoid, mesh also screen film, enterobiasis.
Grass-leaved sweetflag：（Classification system：Acorus tatarinowii）, belong to Araeceae, Acorus graminoid perennial grass
This plant, rhizome tool smell.Leaf full edge lines up two row, spadix（Spadix）, bennet is green, and spathe is lobate.Root
Stem is often made medicinal.The area of 20 meters to 2600 meters of height above sea level is grown on, more lifes are in mountain stream water stone gap or between the flowing water gravel of gully
（Sometimes it is very aquatic length）.The flowering fruit bearing stage 2-6 months.Asia is distributed in, including states such as Northeastern India, Northern Thailand, China.It is main
It controls：Dampness elimination appetizing, slit phlegm of having one's ideas straightened out, inducing resuscitation intelligence development.For gastral cavity ruffian is not hungry, apnea, coma epilepsy, forgetfulness and deafness.
Cloves：Bud for plant clove of myrtaceae.Middle benefit gas, warms up kidney, and drop is inverse.Hiccup is controlled, is vomitted, gastric disorder causing nausea, rush down dysentery, the heart
Abdomen crymodynia, Xuan addictions, hernia, tinea.
Radix Aucklandiae：Radix Aucklandiae is the common name of feverfew Aplotaxis auriculata and radix jurineae.Aplotaxis auriculata（Scientific name：Saussurea
costus）Also known as costus root or dutchmanspipe root, belong to composite family Genus Saussurea.Radix jurineae（Scientific name：Dolomiaea souliei）It is chrysanthemum
The plant of section's Dolomiaea is the endemic plant of China.The ground such as the Sichuan, Yunnan, Tibet of China's Mainland are distributed in, it is grow more
It is wild plant, not yet by artificial introducing and planting in alpine meadow and shrubbery.During the rhizome of both plants is all important
Herbal medicine.Radix Aucklandiae major function：Promoting qi circulation and relieving pain, reinforcing spleen to promote digestion.For chest gastral cavity distending pain, weight after rush down dysentery, dyspepsia, do not feel like eating.
Dried orange peel：Also known as orange peel is rutaceae orange and its ripe pericarp of variety.Evergreen dungarunga of tangerine or filling
Wood is cultivated in hills, low mountain zone, rivers and lakes bank or Plain.It is distributed in each department on the south the Changjiang river.10 to December fruit into
When ripe, fruit is taken, strips pericarp, is dried in the shade or aeration-drying.Wide orange peel (dried orange peel) is cut into 3 to 4 valves more when stripping.Orange peel is (old
Skin) medicinal material point " dried orange peel " and " citrus chachiensis hortorum ".It cures mainly：The abdominal fullness and distention or pain of the taste stagnation of the circulation of vital energy, indigestion.Chest in wet turbid resistance
Bored abdominal distension, indigestion and loss of appetite loose stool.The cough and asthma of phlegm obstructing lung.For chest gastral cavity turgor, deficiency of food vomiting and diarrhoea, coughing with a lot of sputum.
Lysimachia foenum-graecum：Also known as vanilla, eupatorium, Lysimachia sikokiana etc., it is Primulaceae Lysimachia herbaceos perennial, plant height is reachable
60 centimetres, there is strong fragrance after dry.Herb contains similar cumarin aromatic oil, can refine essence, as the fragrance such as tobacco and face cream,
In dry product cartonning can Anti-moth-eating clothing, and hyoscine, tool dispersing wind and cold wards off dirty effect, heresy cold headache, upper qi-stagnant lumbago, chest when controlling
Bored abdominal distension, seminal emission, ascarifuge etc. are rare fragrant plants.
Agalloch eaglewood：The source of agalloch eaglewood is dicotyledon medicine Thymelaeceae magaphanerophytes agalloch eaglewood Aquilaria agallocha
(Lour.) Roxb or suspension culture of Aquilaria sinensis A. sinensis (Lour.) Gilg are injured by nature,（Such as lightning stroke, wind
Folding, damages by worms）Or infected by the grease secreted out of during self-regeneration after artificial destruction by fungi, it coagulates
The secretion formed is exactly agalloch eaglewood.Agar【LIGNUM AQUILARIAE SINENSIS from Hainan of China alias】, suspension culture of Aquilaria sinensis【Domestic agalloch eaglewood seeds】, tabernaemontanus bulrush it is fragrant【Guangdong, Guangxi,
Production agalloch eaglewood is referred to as in Hong Kong】, its title because the region of Edgeworthia chrysantha it is different, Radix Aucklandiae type is different, thus title is different.It cures mainly：The circulation of vital energy in the wrong direction
It pants, vomit that hiccup, abdominal distention, waist and knee void is cold, empty secret, the urine gas leaching of large intestine, man's cold sperm.
Rhizoma atractylodis：Rhizoma atractylodis（Scientific name：Atractylodes Lancea (Thunb.) DC.）：Composite family [WTBX perennial herb
Plant.Root-like stock（Rhizoma atractylodis）：It is pungent, bitter, temperature.Drying damp and strengthening spleen, expelling wind and clearing away cold, improving eyesight, ward off it is dirty.For abdominal distention, diarrhea, water
Swollen, arthralgia pain due to rheumatism, tinea pedis Wei lame, anemofrigid cold, night blindness.
Chinese cassia tree：Dry hide and thick branch skin for Lauraceae aiphyllium plant Chinese cassia tree Cinnamomum cassia Presl.Dry hide
Going to epidermis, person claims the Chinese cassia tree heart, picks up from thick branch or treelet dry hide person claims official osmanthus.Main product is in Guangdong, Guangxi and other places.It cures mainly：For sun
Impotence, Gong Leng, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, Amenorrhea, dysmenorrhoea, warming meridians and promoting circulation of qi.
Menthol：A kind of chemical agent, menthol in the leaf and stem of peppermint by being extracted, white crystal, molecular formula
C10H20O is the main component in peppermint and lavender essential oil.In the world, India is main natural peppermint producing country.
Pharmaceutically be used as excitants, act on skin or mucous membrane, have refrigerant itching-relieving action, it is for oral administration can be used as carminative, for having a headache and
Nose, pharynx, laryngitis etc..
The root of Dahurain angelica：Root is in cone, long 10-20cm, diameter 2-2.5cm.Surface taupe brown has the hole skin of transverse projections, top
There is the stem trace of recess at end.Matter is hard, section white, mealiness foot, and skin zone gathers brown oil drop.It cures mainly:Wind-damp dispelling, apocenosis of invigorating blood circulation, life
Insertion tendon pain.For having a headache, having a toothache, nasosinusitis, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, pruitus.The root of Dahurain angelica also has beauty work(
Effect selects the big and root of Dahurain angelica of the colour purity in vain without mould mark, takes its root, grinds for superfine end, is incorporated into the common skin care item of a bottle, fills
Point stirring and it is even, adhere to using, there is certain whitening effect.
Peppermint：Popular name belongs to other drying herbs for labiate " peppermint ", is born in hill wet more " lunar caustic grass "
By ground river, rhizome grows wild underground.Complete stool green gas fragrance.Leaf spends small lavender, lip, the granule of knot dark violet brown after spending to life
Fruit.Peppermint is one of Chinese conventional Chinese medicine.It is pungent cool property sweating antipyretic medicine, controls influenza, headache, hot eyes, body heat, pharynx
The diseases such as larynx, gum swelling and pain.Neuralgia, pruitus, fash and eczema etc. can be controlled.
Asarum：Alias asarum sieboldii, basin grass asarum, Latin literary fame:Asarum sieboldii Miq. Aristolochiaceaes, asarum
Belong to perennial herb.Rhizome is used as medicine, with for antipyretic, diuresis, analgesia, sedative.(due to containing the poison such as aristolochic acid in asarum double leaf
Property ingredient, 05 edition States Pharmacopoeia specifications asarum medicinal part continue to use ancient method, and recovery is used as medicine with root and rhizome.) asarum have expelling wind and clearing away cold,
The effect of sensible analgesic, warming lung and resolving fluid.According to the pharmacological property of eighteen incompatibilities, asarum cannot be with black false hellebore with use.
Cortex Magnoliae Officinalis：The purple Piao of alias, purple oily Piao, warm Piao etc. in the range of botany are Magnoliaceae, magnolia, and common is thick
Piao (former subspecies) M. officinalis subsp. officinalis and Magnolia bilola (subspecies) M. officinalis
Subsp. two kinds of biloba, main product is in Sichuan, Hubei and other places.It cures mainly：Stagnation of QI due to dyspepsia, abdominal distention constipation, damp retention in middle-jiao, gastral cavity ruffian are spat
It rushes down, phlegm stops up the circulation of vital energy in the wrong direction, chest full of cough.
The preparation method step of above-mentioned composition is as follows：
(1) Patchouli, Radix Glycyrrhizae, Rhizoma Chuanxiong, grass-leaved sweetflag, cloves, Radix Aucklandiae, dried orange peel, Lysimachia foenum-graecum, agalloch eaglewood, rhizoma atractylodis, Chinese cassia tree, the root of Dahurain angelica, thin is taken
Lotus, asarum, Cortex Magnoliae Officinalis are smashed into coarse powder, add water to cook, decocting liquid is filtered, concentration, concentrates alcohol precipitation again, obtains concentrate；
(2) above-mentioned concentrate is taken, after forced air drying, carries out ultramicro grinding, while borneol, menthol are carried out Ultramicro-powder
It is broken, both the above crushed material is crossed No. five sieves (80 mesh sieve), mixes, powder is made.
Wherein, the preparation method of the composition is preferably：
(1) take Patchouli, Radix Glycyrrhizae, Rhizoma Chuanxiong, grass-leaved sweetflag, cloves, Radix Aucklandiae, dried orange peel, Lysimachia foenum-graecum, agalloch eaglewood, rhizoma atractylodis, Chinese cassia tree, the root of Dahurain angelica,
Peppermint, asarum, Cortex Magnoliae Officinalis are ground into coarse powder, add 9-13 times to measure water and decoct 1-3 times, and 1-3 hours each, decocting liquid filtration, filtrate merges,
The clear cream that relative density is 1.10-1.15 is concentrated under reduced pressure into, adds ethyl alcohol that alcohol content is made to be 65%, stands 24 hours, filter, recycling
Ethyl alcohol, concentration, obtains concentrate；
(2) above-mentioned concentrate is taken, after forced air drying, carries out ultramicro grinding, while borneol, menthol are carried out Ultramicro-powder
It is broken, both the above crushed material is crossed No. five sieves (80 mesh sieve), mixes, powder is made.
The preparation method of the composition is most preferably：
(1) Patchouli, Radix Glycyrrhizae, Rhizoma Chuanxiong, grass-leaved sweetflag, cloves, Radix Aucklandiae, dried orange peel, Lysimachia foenum-graecum, agalloch eaglewood, rhizoma atractylodis, Chinese cassia tree, the root of Dahurain angelica, thin is taken
Lotus, asarum, Cortex Magnoliae Officinalis are ground into coarse powder, 10 times of amount water are added to decoct 2 times, 1.5 hours every time, decocting liquid filtration, filtrate merged, and decompression is dense
The clear cream that relative density is 1.10-1.15 is reduced to, adds ethyl alcohol that alcohol content is made to be 65%, stands 24 hours, ethyl alcohol is recycled in filtering,
Concentration, obtains concentrate；
(2) above-mentioned concentrate is taken, after forced air drying, carries out ultramicro grinding, while borneol, menthol are carried out Ultramicro-powder
It is broken, both the above crushed material is crossed No. five sieves (80 mesh sieve), mixes, powder is made.
The powder containing Patchouli has following curative effect as obtained by above-mentioned formula and preparation method：
（1）Returns spleen, stomach, lung channel.With remove dampness by means of aromatics, anti-vomiting, driving away summer heat inducing diaphoresis, diarrhoea abdomen strand, collywobbles abdominal distension, cold stomach are spat
The bored plug of acid, chest diaphragm, cold productive cough cough, lose the appetite, vomitting, diarrhea, mountain breeze miasma, dizzy vehicle are seasick；
（2）It treats children's diarrhoea abdomen to twist, the diseases such as collywobbles abdominal distension will not injure children's internal organs stomach.
Compared with prior art, the present composition has the following technical effect that：
Present composition compatibility is new reasonable, fast for treating the diseases curative effects such as abdominal pain vomiting and diarrhoea, with obvious effects, takes simple, use
Dose is few, has no toxic side effect.
Specific embodiment
Just the present invention is explained further, but embodiment is not the present invention any restriction with embodiment below.
Embodiment 1
Take 70 grams of Patchouli, 45 grams of Radix Glycyrrhizae, 70 grams of Rhizoma Chuanxiong, 70 grams of grass-leaved sweetflag, 70 grams of cloves, 70 grams of Radix Aucklandiae, 70 grams of dried orange peel, spirit fragrant
70 grams of 70 grams of grass, 70 grams of agalloch eaglewood, 70 grams of rhizoma atractylodis, 70 grams of Chinese cassia tree, 25 grams of the root of Dahurain angelica, 7 grams of peppermint, 25 grams of asarum, Cortex Magnoliae Officinalis compositions.It will be upper
State raw material and be ground into coarse powder, add 9 times amount water decoct 1.5 hours, filtering liquid medicine, be concentrated under reduced pressure into relative density be 1.13 it is clear
Cream, adds ethyl alcohol that alcohol content is made to be 65%, stands 24 hours, and ethyl alcohol is recycled in filtering, and concentration obtains concentrate 1000ml.Pass through drum
Air-dry it is dry after, carry out ultramicro grinding, size controlling at 30 μm hereinafter, simultaneously 4 grams of borneol, 3 grams of menthol progress ultramicro grindings,
All two parts of crushed materials are put into V-Mixer and are mixed 30 minutes, are sub-packed in 50 grams by No. five sieves (80 mesh sieve) after crushing
In vial, pack to obtain the final product.
This product is yellowish-brown powder, answers uniform color, no decorative pattern and color spot.Dry to constant weight at 105 DEG C, less loss weight is not
Obtained 2.0%.Water delivery service can directly be used.
Embodiment 2
1. 600 patients of clinical observation have apparent clinical symptoms, and make a definite diagnosis through clinician.It is 80 years old wherein the oldest, most
Eight months small, course of disease longest 10 days is most 3 days short.
2. patient is by age divided into children's group (less than 16 years old), adult group (17-55 Sui), old group (55 years old or more).
The Chinese medicine composition obtained in oral embodiment 1, adult measure twice a day, each 0.3-0.9 grams, and using protect Ji oral liquid as pair
According to oral to protect Ji oral liquid, adult measures three times a day, each 10ml.
3. it cures：Diarrhea, vomiting and diarrhoea, tripe swollen disappear substantially, and functional rehabilitation is normal.It is effective：The symptoms were significantly improved, and diarrhea is spat
It rushes down, tripe swollen significantly reduces.It improves：Symptom mitigates, and diarrhea, vomiting and diarrhoea, tripe swollen mitigate.In vain：Symptom is without change before and after medication.
4. each age group is taken powder containing Patchouli and is taken and protects Ji oral liquid and control Comparison of therapeutic.
By comparison it is found that the powder of the Chinese medicine composition containing Patchouli that embodiment 1 obtains has in treatment abdominal pain vomiting and diarrhoea
Special efficacy, and better than Ji oral liquid is protected, curative effect is particularly evident in treatment Children bellyache is vomited and diarrhoea.In addition, the patient for the treatment of group with
After medicine, sleep state has notable improvement.
Embodiment 3
1. experimental animal：ICR mouse, weight 22.5-26.5g, half male and half female.
2. experimental method：Through prerun, the toxicity of the Chinese medicine composition obtained in embodiment 1 is very low, does not measure LD50, therefore right
Mouse carries out maximum dosage-feeding on the one and measures.Maximum dosage-feeding is 36 grams, after 20 times, 7 days of adult's clinical oral administration dosage
Observation is poisoned to death without an example, all health survival.
Each technical characteristic of embodiment described above can be combined arbitrarily, to make description succinct, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, it is all considered to be the range of this specification record.
Embodiment described above only expresses the several embodiments of the present invention, and description is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that those of ordinary skill in the art are come
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention
Range.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (10)
1. a kind of powder for treating baby diarrhea, it is characterised in that the composition is by Patchouli, Radix Glycyrrhizae, Rhizoma Chuanxiong, borneol, stone Chang
Pu, cloves, Radix Aucklandiae, dried orange peel, Lysimachia foenum-graecum, agalloch eaglewood, rhizoma atractylodis, Chinese cassia tree, menthol, the root of Dahurain angelica, peppermint, asarum, Cortex Magnoliae Officinalis composition.
2. composition as described in claim 1, it is characterised in that the composition is made of component as follows according to the mass fraction：
Patchouli 40-90, Radix Glycyrrhizae 20-60, Rhizoma Chuanxiong 40-90, borneol 3-6, grass-leaved sweetflag 40-90, cloves 40-90, Radix Aucklandiae 40-90, dried orange peel
40-90, Lysimachia foenum-graecum 40-90, agalloch eaglewood 40-90, rhizoma atractylodis 40-90, Chinese cassia tree 40-90, menthol 1-5, root of Dahurain angelica 20-40, peppermint 5-10,
Asarum 20-40, Cortex Magnoliae Officinalis 40-90 are formed.
3. composition as claimed in claim 2, it is characterised in that the composition is made of component as follows according to the mass fraction：
Patchouli 60-80, Radix Glycyrrhizae 40-50, Rhizoma Chuanxiong 60-80, borneol 4-5, grass-leaved sweetflag 60-80, cloves 60-80, Radix Aucklandiae 60-80, dried orange peel
60-80, Lysimachia foenum-graecum 60-80, agalloch eaglewood 60-80, rhizoma atractylodis 60-80, Chinese cassia tree 60-80, menthol 3-4, root of Dahurain angelica 25-30, peppermint 7-9,
Asarum 25-30, Cortex Magnoliae Officinalis 60-80 are formed.
4. composition as claimed in claim 3, it is characterised in that the composition is made of component as follows according to the mass fraction：
It is Patchouli 70, Radix Glycyrrhizae 45, Rhizoma Chuanxiong 70, borneol 4, grass-leaved sweetflag 70, cloves 70, Radix Aucklandiae 70, dried orange peel 70, Lysimachia foenum-graecum 70, agalloch eaglewood 70, grey
Art 70, Chinese cassia tree 70, menthol 3, the root of Dahurain angelica 25, peppermint 7, asarum 25, Cortex Magnoliae Officinalis 70 form.
5. the composition as described in claim 1-4 can be processed into powder, granule, tablet, oral liquid, syrup, glue
Capsule, preferably powder.
6. the preparation method of composition as described in claim 1, it is characterised in that include the following steps：
（1）Take Patchouli, Radix Glycyrrhizae, Rhizoma Chuanxiong, grass-leaved sweetflag, cloves, Radix Aucklandiae, dried orange peel, Lysimachia foenum-graecum, agalloch eaglewood, rhizoma atractylodis, Chinese cassia tree, the root of Dahurain angelica, thin
Lotus, asarum, Cortex Magnoliae Officinalis are ground into coarse powder, add water to cook, and decocting liquid is filtered, and concentration, concentrates alcohol precipitation again, obtains concentrate；
（2）Above-mentioned concentrate is taken, after forced air drying, carries out ultramicro grinding, while borneol, menthol are carried out Ultramicro-powder
It is broken, both the above crushed material is crossed No. five sieves (80 mesh sieve), mixes, powder is made.
7. the preparation method of composition as claimed in claim 6, it is characterised in that include the following steps：
（1）Take Patchouli, Radix Glycyrrhizae, Rhizoma Chuanxiong, grass-leaved sweetflag, cloves, Radix Aucklandiae, dried orange peel, Lysimachia foenum-graecum, agalloch eaglewood, rhizoma atractylodis, Chinese cassia tree, the root of Dahurain angelica, thin
Lotus, asarum, Cortex Magnoliae Officinalis are ground into coarse powder, add 9-13 times to measure water and decoct 1-3 times, and 1-3 hours each, decocting liquid filtration, filtrate merges, subtracts
Pressure is concentrated into the clear cream that relative density is 1.10-1.15, adds ethyl alcohol that alcohol content is made to be 65%, stands 24 hours, second is recycled in filtering
Alcohol, concentration, obtains concentrate；
（2）Above-mentioned concentrate is taken, after forced air drying, carries out ultramicro grinding, while borneol, menthol are carried out Ultramicro-powder
It is broken, both the above crushed material is crossed No. five sieves (80 mesh sieve), mixes, powder is made.
8. the preparation method of composition as claimed in claim 7, it is characterised in that include the following steps：
（1）Take Patchouli, Radix Glycyrrhizae, Rhizoma Chuanxiong, grass-leaved sweetflag, cloves, Radix Aucklandiae, dried orange peel, Lysimachia foenum-graecum, agalloch eaglewood, rhizoma atractylodis, Chinese cassia tree, the root of Dahurain angelica, thin
Lotus, asarum, Cortex Magnoliae Officinalis are ground into coarse powder, 10 times of amount water are added to decoct 2 times, 1.5 hours every time, decocting liquid filtration, filtrate merged, and decompression is dense
The clear cream that relative density is 1.10-1.15 is reduced to, adds ethyl alcohol that alcohol content is made to be 65%, stands 24 hours, ethyl alcohol is recycled in filtering,
Concentration, obtains concentrate；
（2）Above-mentioned concentrate is taken, after forced air drying, carries out ultramicro grinding, while borneol, menthol are carried out Ultramicro-powder
It is broken, both the above crushed material is crossed No. five sieves (80 mesh sieve), mixes, powder is made.
9. the preparation method of composition according to claim 8, it is characterised in that：During concentrated medicament, steam pressure is
0.05-0.15Mpa, vacuum degree 0.06-0.08Mpa, 40-60 DEG C of temperature are concentrated into relative density 1.10~1.20 (50 DEG C)
Clear cream.
10. the preparation method of composition according to claim 8, it is characterised in that after powder makes, in 105 DEG C of dryings extremely
Constant weight, less loss weight must not cross 2.0%.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1368292A (en) * | 2001-02-06 | 2002-09-11 | 杨孟君 | Nano medicing 'Wenzhong Zhixie' and its preparing process |
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2017
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1368292A (en) * | 2001-02-06 | 2002-09-11 | 杨孟君 | Nano medicing 'Wenzhong Zhixie' and its preparing process |
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| Title |
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| 无: "五塔标行军散", 《1药网》 * |
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Application publication date: 20180619 |