CN1049599C - Medicine for treatment of thromboangiitis obliterans - Google Patents
Medicine for treatment of thromboangiitis obliterans Download PDFInfo
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- CN1049599C CN1049599C CN97100779A CN97100779A CN1049599C CN 1049599 C CN1049599 C CN 1049599C CN 97100779 A CN97100779 A CN 97100779A CN 97100779 A CN97100779 A CN 97100779A CN 1049599 C CN1049599 C CN 1049599C
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- medicine
- radix
- thromboangiitis obliterans
- treatment
- realgar
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- 239000003814 drug Substances 0.000 title claims abstract description 30
- 208000033386 Buerger disease Diseases 0.000 title claims abstract description 12
- 206010043540 Thromboangiitis obliterans Diseases 0.000 title claims abstract description 12
- 229940079593 drug Drugs 0.000 title claims description 6
- 239000004863 Frankincense Substances 0.000 claims abstract description 7
- 241000222640 Polyporus Species 0.000 claims abstract description 7
- 229910052957 realgar Inorganic materials 0.000 claims abstract description 7
- 241000628997 Flos Species 0.000 claims description 8
- 239000009636 Huang Qi Substances 0.000 claims description 7
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 7
- 210000000582 semen Anatomy 0.000 claims description 7
- 241000717739 Boswellia sacra Species 0.000 claims description 6
- 241001057584 Myrrha Species 0.000 claims description 6
- 241000131808 Scolopendra Species 0.000 claims description 6
- 235000012907 honey Nutrition 0.000 abstract description 4
- 201000010099 disease Diseases 0.000 abstract description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 3
- 239000000843 powder Substances 0.000 abstract description 3
- 238000002156 mixing Methods 0.000 abstract description 2
- 239000006187 pill Substances 0.000 abstract description 2
- 238000002360 preparation method Methods 0.000 abstract description 2
- 239000002994 raw material Substances 0.000 abstract description 2
- 241000173529 Aconitum napellus Species 0.000 abstract 1
- 244000144730 Amygdalus persica Species 0.000 abstract 1
- 244000061520 Angelica archangelica Species 0.000 abstract 1
- 241000132012 Atractylodes Species 0.000 abstract 1
- 235000003717 Boswellia sacra Nutrition 0.000 abstract 1
- 240000007551 Boswellia serrata Species 0.000 abstract 1
- 235000012035 Boswellia serrata Nutrition 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 240000007311 Commiphora myrrha Species 0.000 abstract 1
- 235000006965 Commiphora myrrha Nutrition 0.000 abstract 1
- 241000510667 Conioselinum Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 235000007265 Myrrhis odorata Nutrition 0.000 abstract 1
- 244000248825 Peltandra virginica Species 0.000 abstract 1
- 235000001188 Peltandra virginica Nutrition 0.000 abstract 1
- 235000006751 Platycodon Nutrition 0.000 abstract 1
- 244000274050 Platycodon grandiflorum Species 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 235000006040 Prunus persica var persica Nutrition 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
- 244000273928 Zingiber officinale Species 0.000 abstract 1
- 235000006886 Zingiber officinale Nutrition 0.000 abstract 1
- 229940107666 astragalus root Drugs 0.000 abstract 1
- 235000008397 ginger Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229930189914 platycodon Natural products 0.000 abstract 1
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- 230000000694 effects Effects 0.000 description 8
- 239000008280 blood Substances 0.000 description 4
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- 230000001737 promoting effect Effects 0.000 description 2
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- 238000007603 infrared drying Methods 0.000 description 1
- 238000004137 mechanical activation Methods 0.000 description 1
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- 231100000862 numbness Toxicity 0.000 description 1
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- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 208000001297 phlebitis Diseases 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
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- 238000003756 stirring Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
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- 238000010792 warming Methods 0.000 description 1
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- 239000010151 yanghe Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention discloses a medicine for treating thromboangiitis obliterans, which belongs to a medicine preparation using natural traditional Chinese medicine materials as raw materials. The medicine is taken after raw astragalus root, platycodon root, angelica, hemlock parsley, tuckahoe, polyporus, Chinese atractylodes, dried ginger, monkshood, cassia twig, peach kernel, safflower, chilopod, dandelion, herba violae, frankincense, myrrh, realgar and raw liquorice are dried and ground into powder and are made into pills by mixing with honey. The medicine is suitable for various disease symptoms of different periods, especially for long-term application of obstinate diseases. The effective rate reaches 96.82%.
Description
The present invention relates to the natural Chinese medicine is the pharmaceutical product of raw material, particularly a kind of medicine for the treatment of thromboangiitis obliterans.
Thromboangiitis obliterans is a kind of chronic general vascular disorder, and its etiology is still not fully aware of, does not have specific treatment yet.Usually adopting surgical operation is lumbar sympathectomy or physiotherapy; Drug therapy often adopts vasodilator.Above-mentioned treatment curative effect is very not remarkable, and dialectical the executing of Chinese medicine controlled typing, adopts different side's medicines to obtain satisfactory effect.
" journal of shanghai Chinese medicine " 19922 " thromboangiitis obliterans progress " report: asthenic cold type is with YANGHE TANG or decoction for Resuscitation; QI and blood stasis type usefulnessization silt soup; Damp-heat type removing dampness Eradicates numbness soup; The heat-toxin type SIMIAOYONGAN TANG.Many doctor's typings difference side medicine is different.
" new the traditional Chinese medical science " 19845 " thromboangiitis obliterans is controlled to test and plucked Jie " disclose the proved recipe of controlling of Dengxian county, Henan Province institute of traditional Chinese medicine, Hebei province's Tangshan Area, Harbin City, Heilongjiang Province city institute of traditional Chinese medicine respectively.As basic side's Radix Angelicae Sinensis, each 15 gram of the Radix Astragali, Radix Codonopsis, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Semen Persicae, Pheretima, each 9 gram of Hirudo, Rhizoma Chuanxiong, each 6 gram of Flos Carthami.Heat-toxin type is drunk and is added Flos Lonicerae, Herba Taraxaci, each 15 gram of Radix Scrophulariae; The YIN-cold type is drunk and is added Radix Aconiti Lateralis Preparata, each 9 gram of Rhizoma Zingiberis, Ramulus Cinnamomi 15 grams; Cooler person of convalescent period adds Ramulus Cinnamomi, each 15 gram of Radix Rehmanniae Preparata; Partial heat person is with Radix Scrophulariae, each 15 gram of the Radix Rehmanniae or the like.
Purpose of the present invention is exactly to be applicable to that in order to provide a kind of dissimilar thromboangiitis obliterans patients of each phase use, especially the medicine of the treatment thromboangiitis obliterans of obstinate disease prolonged application.
The present invention is the principal agent dispelling cold by warming the meridian with Radix Aconiti Lateralis Preparata, Rhizoma Zingiberis, Ramulus Cinnamomi is walked extremity partially to increase its effect, the Scolopendra power of stimulating the menstrual flow is the strongest, Semen Persicae, Flos Carthami are controlled blood Eradicates and are become silted up, the promoting the circulation of blood of enriching blood of Rhizoma Chuanxiong and Radix Angelicae Sinensis compatibility, Poria, the sharp skin of Polyporus eliminating dampness by diuresis, it is strong that Herba Taraxaci, Herba Violae are separated virulence, Olibanum, Myrrha, Realgar Eradicates corruption, granulation promoting, pain relieving more improve body immunity with the Radix Astragali, Poria, Rhizoma Atractylodis spleen invigorating QI invigorating.
The present invention is processed by following weight portion medical material combination:
Radix Astragali 15-30, Radix Platycodonis 15-30, Radix Angelicae Sinensis 10-15, Rhizoma Chuanxiong 10-15,
Poria 10-15, Polyporus 15-20, Rhizoma Atractylodis 10-15, Rhizoma Zingiberis 15-20,
Radix Aconiti Lateralis Preparata 6-10, Ramulus Cinnamomi 10-15, Semen Persicae 10-15, Flos Carthami 10-15,
Herba Taraxaci 10-15, Scolopendra 3-6, Herba Violae 10-15, Olibanum 5-10,
Radix Glycyrrhizae 10-15, Myrrha 5-10, Realgar 1-2.
The ideal weight portion proportioning of preparation pharmaceutical formulation of the present invention is:
Radix Astragali 15, Radix Platycodonis 15, Radix Angelicae Sinensis 12, Rhizoma Chuanxiong 12, Poria 10, Polyporus 15,
Rhizoma Atractylodis 10, Rhizoma Zingiberis 15, Radix Aconiti Lateralis Preparata 6, Ramulus Cinnamomi 10, Semen Persicae 10, Flos Carthami 10,
Herba Taraxaci 10, Scolopendra 6, Herba Violae 10, Olibanum 6, Myrrha 6, Realgar 1.5,
Radix Glycyrrhizae 10.
The method that above-mentioned each component Chinese crude drug is made medicine of the present invention is:
Above-mentioned medical material after 24 hours, was pulverized 80 mesh sieves through 80 ℃ of drying and sterilizings of far-infrared rays drying case, radiosterilization, making pellets by mixing medical powder with honey, every ball 9 grams are gone into to mould shell and are sealed with wax, pack, and every box ten balls are standby.
Drug dose of the present invention and instructions of taking: oral medicine of the present invention every day 2 times, each 2 balls, warm water delivery service, one month is a course of treatment.
Through using clinical drug of the present invention to treat 126 routine patients, clinical cure 42 examples account for 33.33% after three courses of treatment; Produce effects 58 examples account for 46.03%; 22 examples that take a turn for the better account for 17.46%; Invalid 4 examples account for 3.18%; Total effective rate is 96.82%.See attached list.
The curative effect statistical annex
| Classification | Treatment | Produce effects | Take a turn for the better | Invalid | Add up to | ||||
| The example number | ％ | The example number | ％ | The example number | ％ | The example number | ％ | ||
| Phlebitis | 23 | 18.2 | 34 | 26.9 | 9 | 7.1 | 1 | 0.7 | 67 |
| Arteritis | 19 | 15.1 | 24 | 19 | 13 | 10.3 | 3 | 2.3 | 59 |
| Subtotal | 42 | 33.33 | 58 | 46.03 | 22 | 17.46 | 4 | 3.18 | 126 |
Embodiment:
Take by weighing Radix Astragali 15kg, Radix Platycodonis 15kg, Radix Angelicae Sinensis 12kg, Rhizoma Chuanxiong 12kg, Poria 10kg, Polyporus 15kg, Rhizoma Atractylodis 10kg, Rhizoma Zingiberis 15kg, Radix Aconiti Lateralis Preparata 6kg, Ramulus Cinnamomi 10kg, Semen Persicae 10kg, Flos Carthami 10kg, Scolopendra 6kg, Herba Taraxaci 10kg, Herba Violae 10kg, Olibanum 6kg, Myrrha 6kg, Realgar 1.5kg, Radix Glycyrrhizae 10kg.Put into 80 ℃ of drying and sterilizings of far infrared drying case respectively 24 hours, and removed moisture content and the about 19.85kg of airborne dust, can dry medical material 178.65kg, cross 80 mesh sieves after the mechanical activation comminution, adopt cobalt 60 radiosterilizations sterilization mix homogeneously standby.Take by weighing Mel 196.52kg and be cut into shape, go into to mould box and seal, can get 41547 of pills approximately through wax with the above agglomerating bar that is squeezed into of medicated powder stirring that mixes the back, every box ten balls, but packing 4154 boxes, honey is 1.1: 1 with the medicine mixed proportion, every ball weighs 9 grams, its Chinese medicine 4.3 grams, honey 4.7 grams.
This medicine property of medicine gentleness, safety, curative effect height, toxic and side effects is not found in clinical use, total effective rate reaches 96.82%, but is thromboangiitis obliterans patient drug of choice thing.
Claims (2)
1. medicine for the treatment of thromboangiitis obliterans is characterized in that this medicine is that drug regimen by following weight parts forms:
Radix Astragali 15-30, Radix Platycodonis 15-30, Radix Angelicae Sinensis 10-15, Rhizoma Chuanxiong 10-15,
Poria 10-15, Polyporus 15-20, Rhizoma Atractylodis 10-15, Rhizoma Zingiberis 15-20, attached
Sub-6-10, Ramulus Cinnamomi 10-15, Semen Persicae 10-15, Flos Carthami 10-15, Scolopendra
3-6, Herba Taraxaci 10-15, Herba Violae 10-15, Olibanum 5-10, Myrrha 5
-10, Realgar 1-2, Radix Glycyrrhizae 10-15.
2. the medicine of treatment thromboangiitis obliterans according to claim 1 is characterized in that the ideal weight portion proportioning of medicine of the present invention is:
Radix Astragali 15, Radix Platycodonis 15, Radix Angelicae Sinensis 12, Rhizoma Chuanxiong 12, Poria 10, Polyporus 15, grey
Art 10, Rhizoma Zingiberis 15, Radix Aconiti Lateralis Preparata 6, Ramulus Cinnamomi 10, Semen Persicae 10, Flos Carthami 10, Scolopendra 6,
Herba Taraxaci 10, Herba Violae 10, Olibanum 6, Myrrha 6, Realgar 1.5, Radix Glycyrrhizae 10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97100779A CN1049599C (en) | 1997-02-27 | 1997-02-27 | Medicine for treatment of thromboangiitis obliterans |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97100779A CN1049599C (en) | 1997-02-27 | 1997-02-27 | Medicine for treatment of thromboangiitis obliterans |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1159943A CN1159943A (en) | 1997-09-24 |
| CN1049599C true CN1049599C (en) | 2000-02-23 |
Family
ID=5165313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN97100779A Expired - Fee Related CN1049599C (en) | 1997-02-27 | 1997-02-27 | Medicine for treatment of thromboangiitis obliterans |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1049599C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103007113A (en) * | 2013-01-11 | 2013-04-03 | 来玉民 | Traditional Chinese medicinal composition for treating phlebitis and method for preparing same |
-
1997
- 1997-02-27 CN CN97100779A patent/CN1049599C/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| 中医药学报1995(3) 1995.1.1 薛广成等，中药内外兼治血栓闭塞性脉管炎100例 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1159943A (en) | 1997-09-24 |
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| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |