[go: up one dir, main page]

CL2019003924A1 - Uso de pridopidina para el tratamiento de la disminución funcional. (divisional solicitud 201900485). - Google Patents

Uso de pridopidina para el tratamiento de la disminución funcional. (divisional solicitud 201900485).

Info

Publication number
CL2019003924A1
CL2019003924A1 CL2019003924A CL2019003924A CL2019003924A1 CL 2019003924 A1 CL2019003924 A1 CL 2019003924A1 CL 2019003924 A CL2019003924 A CL 2019003924A CL 2019003924 A CL2019003924 A CL 2019003924A CL 2019003924 A1 CL2019003924 A1 CL 2019003924A1
Authority
CL
Chile
Prior art keywords
functional capacity
pridopidine
treatment
divisional application
functional decline
Prior art date
Application number
CL2019003924A
Other languages
English (en)
Inventor
Michael Hayden
Spyridon Papapetropoulos
Juha-Matti Savola
Eli Eyal
Beth Borowsky
Igor D Grachev
Original Assignee
Prilenia Neurotherapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prilenia Neurotherapeutics Ltd filed Critical Prilenia Neurotherapeutics Ltd
Publication of CL2019003924A1 publication Critical patent/CL2019003924A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

ESTA INVENCIÓN PROPORCIONA UN MÉTODO PARA MANTENER LA CAPACIDAD FUNCIONAL, MEJORAR LA CAPACIDAD FUNCIONAL O RETARDAR LA DISMINUCIÓN DE LA CAPACIDAD FUNCIONAL EN UN PACIENTE HUMANO ADMINISTRANDO PERIÓDICAMENTE POR VÍA ORAL UNA COMPOSICIÓN FARMACÉUTICA QUE COMPRENDE PRIDOPIDINA QUE SE ADMINISTRA EN UNA DOSIS DE 90-225 MG AL PACIENTE POR DÍA, PARA MANTENER ASÍ LA CAPACIDAD FUNCIONAL, MEJORAR LA CAPACIDAD FUNCIONAL O RETARDAR LA DISMINUCIÓN DE LA CAPACIDAD FUNCIONAL EN EL PACIENTE HUMANO.
CL2019003924A 2016-08-24 2019-12-31 Uso de pridopidina para el tratamiento de la disminución funcional. (divisional solicitud 201900485). CL2019003924A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662379175P 2016-08-24 2016-08-24
US201662395263P 2016-09-15 2016-09-15
US201662411511P 2016-10-21 2016-10-21
US201662416685P 2016-11-02 2016-11-02

Publications (1)

Publication Number Publication Date
CL2019003924A1 true CL2019003924A1 (es) 2020-05-29

Family

ID=61241181

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2019000485A CL2019000485A1 (es) 2016-08-24 2019-02-22 Uso de pridopidina para el tratamiento de la disminución funcional.
CL2019003924A CL2019003924A1 (es) 2016-08-24 2019-12-31 Uso de pridopidina para el tratamiento de la disminución funcional. (divisional solicitud 201900485).

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CL2019000485A CL2019000485A1 (es) 2016-08-24 2019-02-22 Uso de pridopidina para el tratamiento de la disminución funcional.

Country Status (17)

Country Link
US (1) US11207310B2 (es)
EP (2) EP3504187B8 (es)
JP (2) JP6912574B2 (es)
CN (2) CN115671103A (es)
AU (2) AU2017315783C1 (es)
BR (1) BR112019003732A2 (es)
CA (2) CA3151507C (es)
CL (2) CL2019000485A1 (es)
DK (1) DK3504187T3 (es)
ES (1) ES3025836T3 (es)
FI (1) FI3504187T3 (es)
HU (1) HUE071008T2 (es)
IL (1) IL311081A (es)
MX (2) MX390627B (es)
PL (1) PL3504187T3 (es)
PT (1) PT3504187T (es)
WO (1) WO2018039477A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2013002453A (es) 2010-09-03 2013-08-01 Ivax Int Gmbh Analogos deuterados de pridopidina utiles como estabilizadores dopaminergicos.
US11090297B2 (en) 2013-06-21 2021-08-17 Prilenia Neurotherapeutics Ltd. Pridopidine for treating huntington's disease
PE20160195A1 (es) 2013-06-21 2016-05-14 Teva Pharmaceuticals Int Gmbh Uso de pridopidina en dosis altas para el tratamiento de enfermedad de huntington
TW201613859A (en) * 2014-06-30 2016-04-16 Teva Pharma Analogs of PRIDOPIDINE, their preparation and use
US11471449B2 (en) 2015-02-25 2022-10-18 Prilenia Neurotherapeutics Ltd. Use of pridopidine to improve cognitive function and for treating Alzheimer's disease
CA2977264C (en) 2015-02-25 2021-12-07 Teva Pharmaceuticals International Gmbh Use of pridopidine to improve cognitive function and for treating alzheimer's disease
PL3504187T3 (pl) 2016-08-24 2025-06-09 Prilenia Neurotherapeutics Ltd. Stosowanie pridopidyny w leczeniu zaburzeń czynnościowych
DK3503890T3 (da) * 2016-08-24 2025-01-27 Prilenia Neurotherapeutics Ltd Anvendelse af pridopidin til behandling af dystonier
DK3512833T3 (da) 2016-09-15 2020-10-12 Boehringer Ingelheim Int Heteroarylcarboxamidforbindelser som inhibitorer af ripk2
US12102627B2 (en) 2016-09-16 2024-10-01 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating rett syndrome
EP3678664A1 (en) 2017-09-08 2020-07-15 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
US12036213B2 (en) 2017-09-08 2024-07-16 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
JP2022521457A (ja) * 2019-01-31 2022-04-08 エフ．ホフマン－ラ ロシュ アーゲー ハンチントン病の進行度の評価方法
CN113395964A (zh) 2019-02-04 2021-09-14 普瑞尼亚神经治疗有限公司 用于帕金森氏病和与帕金森症相关的其它疾病的低剂量普利多匹定
CN113950328A (zh) 2019-06-12 2022-01-18 普瑞尼亚神经治疗有限公司 用于治疗亨廷顿病及其症状的包含普利多匹定及其类似物的组合物
BR112022022427A2 (pt) * 2020-05-04 2022-12-13 Prilenia Neurotherapeutics Ltd Tratamento de infecção, doença ou distúrbio viral com o uso de um agonista de s1r seletivo
CN117202906A (zh) * 2021-04-14 2023-12-08 普瑞尼亚神经治疗有限公司 前驱亨廷顿病的治疗
WO2025164698A1 (ja) * 2024-01-31 2025-08-07 株式会社ケイファーマ ハンチントン病治療剤及び治療用組成物

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9702716D0 (sv) 1997-07-15 1997-07-15 Ross Nicholas Waters Substituted phenylazacycloalkanes in the treatment of cognitive disorders
SE9904724D0 (sv) 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
EP1713486A4 (en) * 2003-12-02 2009-04-29 Sheldon Leslie James COMBINED THERAPY FOR THE TREATMENT OF DEMENTIA, DEPRESSION AND APATHY
GT200500063A (es) 2004-04-01 2005-10-14 Metodo para tratar la esquizofrenia y/o anormalidades glucoregulatorias
KR101319235B1 (ko) 2004-10-13 2013-10-16 아이백스 인터내셔널 게엠베하 4-(3-메탄설폰일페닐)-1-ｎ-프로필-피페리딘의 합성 공정
DOP2006000273A (es) 2005-12-08 2007-10-15 Aventis Pharma Inc Uso de un antagonista de cb1 para tratar efectos secundarios y sintomas negativos de la esquizofrenia
EP1815857A1 (en) 2006-02-02 2007-08-08 LEK Pharmaceuticals D.D. A pharmaceutical composition comprising perindopril
US20070286902A1 (en) 2006-06-07 2007-12-13 Abrika Pharmaceuticals Dosage forms comprising a short acting sedative-hypnotic or salt thereof
WO2008127188A1 (en) 2007-04-12 2008-10-23 Allbay Ab N-oxide and/or di-n-oxide derivatives of dopamine receptor stabilizers/modulators displaying improved cardiovascular side-effects profiles
WO2010008486A2 (en) 2008-06-24 2010-01-21 Parkinsons Institute Pluripotent cell lines and methods of use thereof
US8384755B2 (en) 2009-08-26 2013-02-26 Intouch Technologies, Inc. Portable remote presence robot
KR101762460B1 (ko) 2009-09-24 2017-07-27 캡슈겔 벨지엄 엔브이 내산성 캡슐
US20110206782A1 (en) 2010-02-24 2011-08-25 Auspex Pharmaceuticals, Inc. Piperidine modulators of dopamine receptor
WO2011107583A1 (en) * 2010-03-04 2011-09-09 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Substituted 4-phenyl-n-alkyl-piperidines for preventing onset or slowing progression of neurodegenerative disorders
JP2013532233A (ja) 2010-07-02 2013-08-15 アクティエボラゲット・エスコーエッフ 機械構成要素、および表面硬化方法
MX2013002453A (es) 2010-09-03 2013-08-01 Ivax Int Gmbh Analogos deuterados de pridopidina utiles como estabilizadores dopaminergicos.
US8703763B2 (en) 2011-03-02 2014-04-22 Hoffmann-La Roche Inc. Bridged piperidine derivatives
EP2710041A4 (en) 2011-05-18 2014-11-05 Parkinson S Inst ASSAY FOR DETERMINING LRRK2 ACTIVITY IN MORBUS PARKINSON
US9006445B2 (en) 2011-09-07 2015-04-14 IVAX International GmbH Polymorphic form of pridopidine hydrochloride
CA2856749A1 (en) 2011-12-08 2013-06-13 IVAX International GmbH The hydrobromide salt of pridopidine
US9744155B2 (en) * 2012-03-28 2017-08-29 Ixcela, Inc. IPA as a therapeutic agent, as a protective agent, and as a biomarker of disease risk
US20130267552A1 (en) 2012-04-04 2013-10-10 IVAX International GmbH Pharmaceutical compositions for combination therapy
WO2014052935A2 (en) 2012-09-27 2014-04-03 Teva Pharmaceutical Industries Ltd. Combination of rasagiline and pridopidine for treating neurodegenerative disorders, in particular huntington's disease
HK1214553A1 (zh) 2012-09-27 2016-07-29 Teva Pharmaceutical Industries Ltd. 用於治疗神经退行性疾病的拉喹莫德和普利多匹定
US11090297B2 (en) 2013-06-21 2021-08-17 Prilenia Neurotherapeutics Ltd. Pridopidine for treating huntington's disease
PE20160195A1 (es) * 2013-06-21 2016-05-14 Teva Pharmaceuticals Int Gmbh Uso de pridopidina en dosis altas para el tratamiento de enfermedad de huntington
MX377576B (es) 2014-01-22 2025-03-04 Prilenia Neurotherapeutics Ltd Formulaciones de pridopidina de liberación modificada.
TW201613859A (en) 2014-06-30 2016-04-16 Teva Pharma Analogs of PRIDOPIDINE, their preparation and use
JP2018505147A (ja) 2014-12-22 2018-02-22 テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハー プリドピジンのｌ−酒石酸塩
CA2977264C (en) 2015-02-25 2021-12-07 Teva Pharmaceuticals International Gmbh Use of pridopidine to improve cognitive function and for treating alzheimer's disease
WO2016138135A1 (en) 2015-02-25 2016-09-01 Teva Pharmaceuticals International Gmbh Sigma-1 receptor modulators for treating huntington's disease
AR105434A1 (es) 2015-07-22 2017-10-04 Teva Pharmaceuticals Int Gmbh Proceso para preparar pridopidina
WO2017015615A1 (en) 2015-07-22 2017-01-26 Teva Pharmaceuticals International Gmbh Pridopidine base formulations and their use
WO2017048457A1 (en) 2015-09-18 2017-03-23 Teva Pharmaceuticals Industries Ltd. Combination of laquinimod and pridopidine to treat multiple sclerosis
CA3015512C (en) 2016-02-24 2024-01-16 Teva Pharmaceuticals International Gmbh Treatment of neurodegenerative eye disease using pridopidine
PL3504187T3 (pl) 2016-08-24 2025-06-09 Prilenia Neurotherapeutics Ltd. Stosowanie pridopidyny w leczeniu zaburzeń czynnościowych
DK3503890T3 (da) 2016-08-24 2025-01-27 Prilenia Neurotherapeutics Ltd Anvendelse af pridopidin til behandling af dystonier
CA3036842A1 (en) 2016-09-15 2018-03-22 Prilenia Therapeutics Development Ltd. Use of pridopidine for the treatment of anxiety and depression
MX388845B (es) 2016-09-16 2025-03-20 Prilenia Neurotherapeutics Ltd Uso de pridopidina para tratar el sindrome de rett.
WO2018053275A1 (en) 2016-09-16 2018-03-22 Teva Pharmaceuticals International Gmbh Use of pridopidine for the treatment of familial dysautonomia
PL3570940T3 (pl) 2017-01-20 2024-06-17 Prilenia Neurotherapeutics Ltd. Pridopidyna do zastosowania w leczeniu zespołu łamliwego chromosomu x
EA202090510A1 (ru) 2017-08-14 2020-06-08 Приления Ньюротерапьютикс Лтд. Способ лечения бокового амиотрофического склероза придопидином
MX2020002310A (es) 2017-08-30 2020-09-17 Prilenia Neurotherapeutics Ltd Formas de dosificacion de alta concentracion de pridopidina.

Also Published As

Publication number Publication date
EP3504187B1 (en) 2025-02-19
CA3035092C (en) 2022-05-31
EP3504187B8 (en) 2025-03-26
HUE071008T2 (hu) 2025-07-28
CN109923102A (zh) 2019-06-21
BR112019003732A2 (pt) 2020-02-18
EP4516356A2 (en) 2025-03-05
EP4516356A3 (en) 2025-05-14
MX390627B (es) 2025-03-21
PL3504187T3 (pl) 2025-06-09
CA3151507A1 (en) 2018-03-01
JP6912574B2 (ja) 2021-08-04
MX2019002265A (es) 2019-10-30
CN115671103A (zh) 2023-02-03
IL311081A (en) 2024-04-01
NZ751156A (en) 2021-01-29
DK3504187T3 (da) 2025-04-14
JP2021119186A (ja) 2021-08-12
AU2017315783C1 (en) 2020-12-24
MX2022003072A (es) 2022-06-17
CL2019000485A1 (es) 2019-07-12
AU2020223736A1 (en) 2020-09-17
WO2018039477A1 (en) 2018-03-01
AU2020223736B2 (en) 2022-04-07
PT3504187T (pt) 2025-05-09
CN109923102B (zh) 2022-11-15
JP2019524898A (ja) 2019-09-05
US11207310B2 (en) 2021-12-28
EP3504187A4 (en) 2020-05-06
EP3504187A1 (en) 2019-07-03
ES3025836T3 (en) 2025-06-09
US20180055832A1 (en) 2018-03-01
AU2017315783B2 (en) 2020-05-28
CA3035092A1 (en) 2018-03-01
FI3504187T3 (fi) 2025-04-05
CA3151507C (en) 2024-05-28
AU2017315783A1 (en) 2019-04-11

Similar Documents

Publication Publication Date Title
CL2019003924A1 (es) Uso de pridopidina para el tratamiento de la disminución funcional. (divisional solicitud 201900485).
MX2015017307A (es) Uso de pridopidina en dosis altas para el tratamiento de enfermedad de huntington.
ECSP20069416A (es) Tratamiento de la hidradenitis supurativa mediante el uso de inhibidores de jak
NI201100147A (es) Métodos para tratar infartos agudos de miocardio y trastornos relacionados.
ECSP088874A (es) Uso de flibanserina para el tratamiento de trastornos posmenopausicos del deseo sexual
SV2015005115A (es) Derivados de la pirazolopirrolidina y su uso en el tratamiento de enfermedades
MX2015016344A (es) Derivados de imidazo-pirrolidinona y su uso en el tratamiento de enfermedades.
BRPI0611705A2 (pt) composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso de composto
DK1891038T3 (da) Substituerede n-arylpyrrolidiner som selektive androgenreceptormodulatorer
BR112015029401A8 (pt) derivados de pirazolo-pirrolidin-4-ona, seus usos, e composição e combinação farmacêuticas
UY30901A (es) Nuevos metodos
UY39510A (es) Compuestos macrocíclicos y métodos para usarlos
PH12019500328A1 (en) Aza-indazole compounds for use in tendon and/or ligament injuries
MX2021015543A (es) Derivado de pirimidina que inhibe el crecimiento de celulas cancerosas y uso medicinal del mismo.
ECSP22032016A (es) Inhibidor de irak y método de preparación para el mismo y uso del mismo
CO2019004004A2 (es) Composición farmacéutica y método para el tratamiento de la enfermedad del hígado graso no alcohólico
MX2022015629A (es) Uso de vibegron para tratar vejiga sobreactiva.
PE20181332A1 (es) Metodos de sedacion y formulacion parenteral para uso durante el tratamiento de cuidados criticos
AR111374A1 (es) Uso de lik066 en pacientes con insuficiencia cardíaca
MX2023004516A (es) Uso de pridopidina y analogos para el tratamiento de la ansiedad y la depresion.
AR108792A1 (es) Composiciones que comprenden timolol
MX2020000702A (es) Composiciones solidas orales de betahistina de liberacion prolongada no pulsatil.
EA201990553A1 (ru) Применение придопидина для лечения ухудшения функциональной способности
BR112023024085A2 (pt) Composto usado como inibidor de bcr-abl
EA202190247A1 (ru) ПРИМЕНЕНИЕ рГЦ СТИМУЛЯТОРОВ ДЛЯ ЛЕЧЕНИЯ МИТОХОНДРИАЛЬНЫХ ЗАБОЛЕВАНИЙ