CL2018003573A1 - Anticuerpos anti-c5 y métodos de uso. - Google Patents

Anticuerpos anti-c5 y métodos de uso.

Info

Publication number: CL2018003573A1
Authority: CL; Chile
Prior art keywords: antibody; present; provides; antibodies; methods
Prior art date: 2016-06-17

Application number

CL2018003573A

Other languages

English (en)

Spanish (es)

Inventor

Zenjiro Sampei

Yoshinao Ruike

Original Assignee

Chugai Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-06-17

Filing date

2018-12-12

Publication date

2019-02-01

2018-12-12 Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd

2019-02-01 Publication of CL2018003573A1 publication Critical patent/CL2018003573A1/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Microbiology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

CL2018003573A 2016-06-17 2018-12-12 Anticuerpos anti-c5 y métodos de uso. CL2018003573A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2016120325		2016-06-17

Publications (1)

Publication Number	Publication Date
CL2018003573A1 true CL2018003573A1 (es)	2019-02-01

Family

ID=59969459

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CL2018003573A CL2018003573A1 (es)	2016-06-17	2018-12-12	Anticuerpos anti-c5 y métodos de uso.

Country Status (19)

Country	Link
EP (1)	EP3472316A4 (zh)
JP (4)	JP6202774B1 (zh)
KR (2)	KR101852739B1 (zh)
CN (3)	CN115960223A (zh)
AU (1)	AU2017285763B2 (zh)
BR (1)	BR112018075688A2 (zh)
CA (1)	CA3021956A1 (zh)
CL (1)	CL2018003573A1 (zh)
CR (1)	CR20190013A (zh)
EA (1)	EA201990018A1 (zh)
IL (2)	IL300611A (zh)
MX (2)	MX2018015030A (zh)
MY (1)	MY187848A (zh)
PE (2)	PE20240825A1 (zh)
PH (1)	PH12018502354B1 (zh)
SG (2)	SG11201705584VA (zh)
TW (5)	TWI610941B (zh)
UA (1)	UA126561C2 (zh)
WO (1)	WO2017217524A1 (zh)

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TWI654204B (zh)	2010-11-30	2019-03-21	中外製藥股份有限公司	具有鈣依存性的抗原結合能力之抗體
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WO2017110981A1 (en)	2015-12-25	2017-06-29	Chugai Seiyaku Kabushiki Kaisha	Anti-myostatin antibodies and methods of use
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CA3078362A1 (en) *	2017-10-04	2019-04-11	Alexion Pharmaceuticals, Inc.	Dosage and administration of anti-c5 antibodies for treatment of patients with membranoproliferative glomerulonephritis
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BR112021004141A2 (pt) *	2018-09-06	2021-05-25	The Trustees Of The University Of Pennsylvania	anticorpo dependente de ph que se liga especificamente a c5 humano, métodos para tratar uma doença ou distúrbio mediado pela via do complemento em um indivíduo e para reduzir a atividade de um sistema complemento de um indivíduo, célula, e, animal não humano geneticamente modificado.
WO2020219922A1 (en) *	2019-04-24	2020-10-29	The Trustees Of The University Of Pennsylvania	Bi-functional humanized anti-c5 antibodies and factor h fusion proteins and uses thereof
CN113563467A (zh) *	2020-04-28	2021-10-29	上海普铭生物科技有限公司	针对人补体蛋白c5的抗体及其应用
WO2022012606A1 (en) *	2020-07-15	2022-01-20	Biosion Inc.	Antibodies binding c5 and uses thereof
EP4267612A4 (en) *	2020-12-25	2024-09-04	The Trustees of the University of Pennsylvania	HUMANIZED ANTI-C5 ANTIBODIES AND FACTOR H FUSION PROTEINS AND THEIR USES

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2017
- 2017-06-16 TW TW106120143A patent/TWI610941B/zh active
- 2017-06-16 EP EP17813418.5A patent/EP3472316A4/en active Pending
- 2017-06-16 TW TW112120479A patent/TW202337903A/zh unknown
- 2017-06-16 EA EA201990018A patent/EA201990018A1/ru unknown
- 2017-06-16 PH PH1/2018/502354A patent/PH12018502354B1/en unknown
- 2017-06-16 WO PCT/JP2017/022253 patent/WO2017217524A1/en not_active Ceased
- 2017-06-16 CR CR20190013A patent/CR20190013A/es unknown
- 2017-06-16 PE PE2023002969A patent/PE20240825A1/es unknown
- 2017-06-16 SG SG11201705584VA patent/SG11201705584VA/en unknown
- 2017-06-16 MX MX2018015030A patent/MX2018015030A/es unknown
- 2017-06-16 AU AU2017285763A patent/AU2017285763B2/en active Active
- 2017-06-16 PE PE2018003148A patent/PE20190394A1/es unknown
- 2017-06-16 BR BR112018075688-1A patent/BR112018075688A2/pt unknown
- 2017-06-16 UA UAA201810992A patent/UA126561C2/uk unknown
- 2017-06-16 TW TW111107923A patent/TWI807666B/zh active
- 2017-06-16 KR KR1020177020545A patent/KR101852739B1/ko active Active
- 2017-06-16 CA CA3021956A patent/CA3021956A1/en active Pending
- 2017-06-16 SG SG10201800265UA patent/SG10201800265UA/en unknown
- 2017-06-16 TW TW114113992A patent/TW202532438A/zh unknown
- 2017-06-16 CN CN202211018018.5A patent/CN115960223A/zh active Pending
- 2017-06-16 MY MYPI2018002581A patent/MY187848A/en unknown
- 2017-06-16 CN CN201780036916.4A patent/CN109312326B/zh active Active
- 2017-06-16 TW TW106141573A patent/TWI789369B/zh active
- 2017-06-16 IL IL300611A patent/IL300611A/en unknown
- 2017-06-16 KR KR1020187010179A patent/KR102226975B1/ko active Active
- 2017-06-16 CN CN202211023851.9A patent/CN115925922A/zh active Pending
- 2017-06-16 JP JP2017118226A patent/JP6202774B1/ja active Active
- 2017-08-28 JP JP2017162934A patent/JP7032077B2/ja active Active
2018
- 2018-12-04 MX MX2023001360A patent/MX2023001360A/es unknown
- 2018-12-12 CL CL2018003573A patent/CL2018003573A1/es unknown
- 2018-12-12 IL IL263657A patent/IL263657B2/en unknown
2022
- 2022-02-24 JP JP2022026406A patent/JP2022091748A/ja active Pending
2024
- 2024-04-30 JP JP2024073302A patent/JP2024102181A/ja active Pending

Also Published As

Publication number	Publication date
JP2024102181A (ja)	2024-07-30
CR20190013A (es)	2019-03-05
CN109312326A (zh)	2019-02-05
WO2017217524A1 (en)	2017-12-21
JP7032077B2 (ja)	2022-03-08
NZ748003A (en)	2024-12-20
TW202239766A (zh)	2022-10-16
MY187848A (en)	2021-10-26
KR102226975B1 (ko)	2021-03-11
PE20240825A1 (es)	2024-04-18
AU2017285763B2 (en)	2024-02-01
TW201808996A (zh)	2018-03-16
MX2018015030A (es)	2019-04-22
JP6202774B1 (ja)	2017-09-27
TW202532438A (zh)	2025-08-16
UA126561C2 (uk)	2022-11-02
TW202337903A (zh)	2023-10-01
PH12018502354A1 (en)	2019-09-23
CN115925922A (zh)	2023-04-07
SG10201800265UA (en)	2018-02-27
IL263657B1 (en)	2025-08-01
IL263657B2 (en)	2025-12-01
JP2022091748A (ja)	2022-06-21
TWI807666B (zh)	2023-07-01
PE20190394A1 (es)	2019-03-13
TWI610941B (zh)	2018-01-11
AU2017285763A1 (en)	2018-11-08
IL300611A (en)	2023-04-01
RU2019100222A3 (zh)	2020-11-05
JP2017226655A (ja)	2017-12-28
EA201990018A1 (ru)	2019-08-30
KR20190009273A (ko)	2019-01-28
CN115960223A (zh)	2023-04-14
EP3472316A4 (en)	2020-01-08
KR101852739B1 (ko)	2018-04-30
CN109312326B (zh)	2022-09-09
EP3472316A1 (en)	2019-04-24
JP2018009021A (ja)	2018-01-18
TWI789369B (zh)	2023-01-11
MX2023001360A (es)	2023-02-27
PH12018502354B1 (en)	2024-02-23
CA3021956A1 (en)	2017-12-21
IL263657A (en)	2019-01-31
RU2019100222A (ru)	2020-07-17
SG11201705584VA (en)	2018-05-30
TW201809000A (zh)	2018-03-16
BR112018075688A2 (pt)	2019-04-02

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