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CL2018002787A1 - Compuestos de aminopurina sustituida, composiciones de estos y métodos de tratamiento con estos. - Google Patents

Compuestos de aminopurina sustituida, composiciones de estos y métodos de tratamiento con estos.

Info

Publication number
CL2018002787A1
CL2018002787A1 CL2018002787A CL2018002787A CL2018002787A1 CL 2018002787 A1 CL2018002787 A1 CL 2018002787A1 CL 2018002787 A CL2018002787 A CL 2018002787A CL 2018002787 A CL2018002787 A CL 2018002787A CL 2018002787 A1 CL2018002787 A1 CL 2018002787A1
Authority
CL
Chile
Prior art keywords
treatment
methods
compositions
compounds
substituted aminopurine
Prior art date
Application number
CL2018002787A
Other languages
English (en)
Inventor
Robert Hubbard
Heather Raymon
John F Boylan
Gordon L Bray
Ellen Filvaroff
David Mikolon
Tao Shi
Tam M Tran
Toshiya Tsuji
Lilly L Wong
Suichan Xu
Dan Zhu
Original Assignee
Signal Pharm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Signal Pharm Llc filed Critical Signal Pharm Llc
Publication of CL2018002787A1 publication Critical patent/CL2018002787A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE PROPORCIONAN EN LA PRESENTE MÉTODOS PARA EL TRATAMIENTO O PREVENCIÓN DE UN CÁNCER, QUE INCLUYEN TUMORES SÓLIDOS Y CÁNCERES HEMATOLÓGICOS, QUE COMPRENDEN ADMINISTRAR UNA CANTIDAD EFICAZ DE COMPUESTOS DE AMINOPURINA DE FÓRMULA (I) Y COMPOSICIONES QUE COMPRENDEN UNA CANTIDAD EFICAZ DE DICHOS COMPUESTOS.
CL2018002787A 2016-04-01 2018-09-28 Compuestos de aminopurina sustituida, composiciones de estos y métodos de tratamiento con estos. CL2018002787A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662317412P 2016-04-01 2016-04-01

Publications (1)

Publication Number Publication Date
CL2018002787A1 true CL2018002787A1 (es) 2019-01-18

Family

ID=59959573

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2018002787A CL2018002787A1 (es) 2016-04-01 2018-09-28 Compuestos de aminopurina sustituida, composiciones de estos y métodos de tratamiento con estos.

Country Status (15)

Country Link
US (1) US10576085B2 (es)
EP (1) EP3436018A4 (es)
JP (1) JP7014731B2 (es)
KR (1) KR102356433B1 (es)
CN (1) CN109069512B (es)
AU (1) AU2017241837B2 (es)
BR (1) BR112018070163A2 (es)
CA (1) CA3018986A1 (es)
CL (1) CL2018002787A1 (es)
EA (1) EA039392B1 (es)
IL (1) IL262007B2 (es)
MX (1) MX379513B (es)
NZ (1) NZ746554A (es)
SG (2) SG10202009589UA (es)
WO (1) WO2017173206A1 (es)

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JOP20180026A1 (ar) 2017-03-31 2019-01-30 Univ Leuven Kath مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
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JP7287955B2 (ja) 2017-10-04 2023-06-06 セルジーン コーポレイション シス－４－［２－｛［（３ｓ，４ｒ）－３－フルオロオキサン－４－イル］アミノ｝－８－（２，４，６－トリクロロアニリノ）－９ｈ－プリン－９－イル］－１－メチルシクロヘキサン－１－カルボキサミドの組成物及び使用方法
MX2020010417A (es) 2018-04-03 2021-01-08 Blueprint Medicines Corp Inhibidor de ret para uso en tratar cancer que tiene una alteracion de ret.
WO2020033838A2 (en) * 2018-08-10 2020-02-13 Blueprint Medicines Corporation Treatment of egfr-mutant cancer
JP7653362B2 (ja) * 2019-04-16 2025-03-28 ビバーチェ セラピューティクス，インク． 二環式化合物
US12122787B2 (en) 2019-09-20 2024-10-22 Shanghai Jemincare Pharmaceuticals Co., Ltd Fused pyridone compound, and preparation method therefor and use thereof
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CN114681456A (zh) * 2022-02-23 2022-07-01 中山大学附属第六医院 Plx3397在结直肠癌的治疗中的用途

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MX379439B (es) * 2016-04-01 2025-03-10 Signal Pharm Llc Formas sólidas de (1s,4s)-4-(2-(((3s,4r)-3-fluorotetrahidro-2h-piran-4-il)amino)-8-((2,4,6-triclorofenil)amino)-9h-purin-9-il)-1-metilciclohexano-1-carboxamida y métodos para utilizarlas.

Also Published As

Publication number Publication date
BR112018070163A2 (pt) 2019-01-29
AU2017241837B2 (en) 2021-07-22
JP7014731B2 (ja) 2022-02-01
SG11201808388QA (en) 2018-10-30
US20170281633A1 (en) 2017-10-05
IL262007B2 (en) 2023-04-01
WO2017173206A1 (en) 2017-10-05
CN109069512A (zh) 2018-12-21
IL262007B (en) 2022-12-01
MX2018011992A (es) 2019-01-24
EA039392B1 (ru) 2022-01-21
EP3436018A1 (en) 2019-02-06
NZ746554A (en) 2023-03-31
SG10202009589UA (en) 2020-10-29
JP2019510066A (ja) 2019-04-11
IL262007A (en) 2018-10-31
EA201892229A1 (ru) 2019-03-29
KR20180126497A (ko) 2018-11-27
EP3436018A4 (en) 2019-11-13
AU2017241837A1 (en) 2018-10-25
CA3018986A1 (en) 2017-10-05
US10576085B2 (en) 2020-03-03
CN109069512B (zh) 2022-06-14
KR102356433B1 (ko) 2022-01-27
MX379513B (es) 2025-03-11

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