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CL2018000742A1 - Uso de trientina para el suministro de cobre a un tejido isquémico - Google Patents

Uso de trientina para el suministro de cobre a un tejido isquémico

Info

Publication number
CL2018000742A1
CL2018000742A1 CL2018000742A CL2018000742A CL2018000742A1 CL 2018000742 A1 CL2018000742 A1 CL 2018000742A1 CL 2018000742 A CL2018000742 A CL 2018000742A CL 2018000742 A CL2018000742 A CL 2018000742A CL 2018000742 A1 CL2018000742 A1 CL 2018000742A1
Authority
CL
Chile
Prior art keywords
copper
ischemic tissue
trientine
supply
repair
Prior art date
Application number
CL2018000742A
Other languages
English (en)
Inventor
Yujian James Kang
Original Assignee
Innolife Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innolife Co Ltd filed Critical Innolife Co Ltd
Publication of CL2018000742A1 publication Critical patent/CL2018000742A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/131—Amines acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Procedimientos de reparación y regeneración de un tejido isquémico mediante la estimulación de la redistribución y del uso de nuevo de cobre administrando una composición que comprende una tetramina quelante del cobre, tal como la trientina. Procedimientos y composiciones para el aumento del nivel de cobre intracelular y/o la inducción de la reparación de un tejido isquémico en un individuo. El aumento del nivel de cobre en un tejido isquémico puede estimular las actividades transcripcionales del HIF-1 dependientes del cobre y la reparación tisular.
CL2018000742A 2015-09-24 2018-03-21 Uso de trientina para el suministro de cobre a un tejido isquémico CL2018000742A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2015/090528 WO2017049529A1 (en) 2015-09-24 2015-09-24 A pharmaceutical composition comprising a copper chelating tetramine and the use thereof

Publications (1)

Publication Number Publication Date
CL2018000742A1 true CL2018000742A1 (es) 2018-11-09

Family

ID=58385664

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2018000742A CL2018000742A1 (es) 2015-09-24 2018-03-21 Uso de trientina para el suministro de cobre a un tejido isquémico

Country Status (18)

Country Link
US (2) US11033579B2 (es)
EP (1) EP3352743A4 (es)
JP (1) JP7041053B2 (es)
KR (1) KR20180055877A (es)
CN (2) CN108697669B (es)
AU (1) AU2016328156B2 (es)
CA (1) CA2998958C (es)
CL (1) CL2018000742A1 (es)
CO (1) CO2018004189A2 (es)
EA (1) EA037045B1 (es)
EC (1) ECSP18031122A (es)
HK (1) HK1259032A1 (es)
IL (1) IL257904B (es)
MX (1) MX391462B (es)
NZ (1) NZ740728A (es)
PE (1) PE20181166A1 (es)
UA (1) UA123503C2 (es)
WO (2) WO2017049529A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
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WO2016168993A1 (en) 2015-04-22 2016-10-27 Innolife Co., Ltd. Methods of tissue repair and regeneration
WO2017049529A1 (en) 2015-09-24 2017-03-30 Innolife Co., Ltd. A pharmaceutical composition comprising a copper chelating tetramine and the use thereof
AU2020294694A1 (en) * 2019-06-17 2022-02-03 Philera New Zealand Ltd. Combination treatments for central nervous system disorders
KR102508657B1 (ko) * 2021-02-17 2023-03-10 성균관대학교산학협력단 금-구리 나노입자를 유효성분으로 포함하는 허혈성 질환 예방 또는 치료용 조성물
JP2024509193A (ja) * 2021-03-05 2024-02-29 フィリーラ ニュー ジーランド リミテッド 銅障害の処置
CA3265528A1 (en) * 2022-08-27 2024-03-07 Biophore India Pharmaceuticals Pvt. Ltd "LIQUID DOSAGE FORMS OF TRIENTINE"
CN115554473A (zh) * 2022-10-25 2023-01-03 华中科技大学同济医学院附属协和医院 去细胞心脏瓣膜复合材料及其制备方法和应用
AU2024269697A1 (en) 2023-05-05 2025-12-04 Cong Nhan Huynh Pharmaceuticals containing chelators with strong zn ions-holding feature for the treatment of symptoms and diseases caused by microorganisms/diseases caused by toxins or neurotoxins/cancer/several syndromes

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Also Published As

Publication number Publication date
JP2018531931A (ja) 2018-11-01
IL257904A (en) 2018-05-31
EP3352743A1 (en) 2018-08-01
CN117338762B (zh) 2025-12-19
CO2018004189A2 (es) 2018-07-19
US20210379102A1 (en) 2021-12-09
EA201890753A1 (ru) 2018-08-31
WO2017049529A1 (en) 2017-03-30
HK1259032A1 (zh) 2019-11-22
NZ740728A (en) 2019-07-26
US11033579B2 (en) 2021-06-15
KR20180055877A (ko) 2018-05-25
AU2016328156A1 (en) 2018-04-12
AU2016328156B2 (en) 2022-03-17
EA037045B1 (ru) 2021-01-29
US12076340B2 (en) 2024-09-03
CA2998958A1 (en) 2017-03-30
WO2017050271A1 (en) 2017-03-30
MX2018003434A (es) 2018-11-09
UA123503C2 (uk) 2021-04-14
ECSP18031122A (es) 2018-05-31
CN117338762A (zh) 2024-01-05
JP7041053B2 (ja) 2022-03-23
IL257904B (en) 2021-04-29
PE20181166A1 (es) 2018-07-19
EP3352743A4 (en) 2019-07-03
BR112018005638A2 (pt) 2018-10-09
CA2998958C (en) 2020-12-22
MX391462B (es) 2025-03-21
CN108697669A (zh) 2018-10-23
US20180296598A1 (en) 2018-10-18
CN108697669B (zh) 2023-08-15

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