CL2012003548A1 - Composicion farmaceutica de liberacion modificada que comprende esferas de liberacion inmediata y esferas de liberacion demorada de acido 2-[3-ciano-4-(2-metilpropoxi)fenil]-4-metiltiazol-5-carboxilico (febuxostat), inhibidor selectivo de xantina oxidorreductasa; forma de dosificacion; y metodo de tratamiento para gota, entre otros. - Google Patents
Composicion farmaceutica de liberacion modificada que comprende esferas de liberacion inmediata y esferas de liberacion demorada de acido 2-[3-ciano-4-(2-metilpropoxi)fenil]-4-metiltiazol-5-carboxilico (febuxostat), inhibidor selectivo de xantina oxidorreductasa; forma de dosificacion; y metodo de tratamiento para gota, entre otros.Info
- Publication number
- CL2012003548A1 CL2012003548A1 CL2012003548A CL2012003548A CL2012003548A1 CL 2012003548 A1 CL2012003548 A1 CL 2012003548A1 CL 2012003548 A CL2012003548 A CL 2012003548A CL 2012003548 A CL2012003548 A CL 2012003548A CL 2012003548 A1 CL2012003548 A1 CL 2012003548A1
- Authority
- CL
- Chile
- Prior art keywords
- spheres
- release
- febuxostat
- methylthiazol
- methylpropoxy
- Prior art date
Links
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical compound O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title 2
- BQSJTQLCZDPROO-UHFFFAOYSA-N febuxostat Chemical compound C1=C(C#N)C(OCC(C)C)=CC=C1C1=NC(C)=C(C(O)=O)S1 BQSJTQLCZDPROO-UHFFFAOYSA-N 0.000 title 2
- 201000005569 Gout Diseases 0.000 title 1
- 102000004316 Oxidoreductases Human genes 0.000 title 1
- 108090000854 Oxidoreductases Proteins 0.000 title 1
- 230000003111 delayed effect Effects 0.000 title 1
- 239000002552 dosage form Substances 0.000 title 1
- 229960005101 febuxostat Drugs 0.000 title 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229940075420 xanthine Drugs 0.000 title 1
Classifications
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35516410P | 2010-06-16 | 2010-06-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2012003548A1 true CL2012003548A1 (es) | 2013-09-06 |
Family
ID=45328897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2012003548A CL2012003548A1 (es) | 2010-06-16 | 2012-12-14 | Composicion farmaceutica de liberacion modificada que comprende esferas de liberacion inmediata y esferas de liberacion demorada de acido 2-[3-ciano-4-(2-metilpropoxi)fenil]-4-metiltiazol-5-carboxilico (febuxostat), inhibidor selectivo de xantina oxidorreductasa; forma de dosificacion; y metodo de tratamiento para gota, entre otros. |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US9248119B2 (es) |
| EP (1) | EP2582812B1 (es) |
| JP (2) | JP5865904B2 (es) |
| KR (1) | KR101872189B1 (es) |
| CN (1) | CN103210084B (es) |
| AU (2) | AU2011268445B2 (es) |
| BR (1) | BR112012032033A2 (es) |
| CA (1) | CA2801930A1 (es) |
| CL (1) | CL2012003548A1 (es) |
| CO (1) | CO6650415A2 (es) |
| EC (1) | ECSP13012394A (es) |
| ES (1) | ES2669184T3 (es) |
| IL (2) | IL223455B (es) |
| JO (1) | JO3450B1 (es) |
| MX (2) | MX361138B (es) |
| MY (1) | MY167126A (es) |
| NZ (1) | NZ604646A (es) |
| PE (2) | PE20130574A1 (es) |
| PH (1) | PH12012502485A1 (es) |
| RU (1) | RU2602188C2 (es) |
| SG (1) | SG186301A1 (es) |
| TW (1) | TW201202249A (es) |
| UA (1) | UA112632C2 (es) |
| WO (1) | WO2011159745A1 (es) |
| ZA (1) | ZA201209386B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5669837B2 (ja) * | 2010-06-16 | 2015-02-18 | 帝人ファーマ株式会社 | 放出制御型の有核錠剤 |
| MY160963A (en) * | 2010-06-25 | 2017-03-31 | Teijin Pharma Ltd | Sustained-release therapeutic agent for hypertension and renal dysfunction |
| NZ605562A (en) * | 2010-07-09 | 2013-11-29 | Teijin Pharma Ltd | Deuterated benzylbenzene derivatives and methods of use |
| WO2012153313A1 (en) * | 2011-05-11 | 2012-11-15 | Ranbaxy Laboratories Limited | Pharmaceutical composition of febuxostat |
| WO2012172461A1 (en) * | 2011-06-13 | 2012-12-20 | Ranbaxy Laboratories Limited | Pharmaceutical compositions of febuxostat |
| CA2862602A1 (en) * | 2012-01-27 | 2013-08-01 | Teijin Pharma Limited | Therapeutic agent for diabetes |
| WO2014009817A1 (en) * | 2012-07-12 | 2014-01-16 | Alembic Pharmaceuticals Limited | Pharmaceutical composition of febuxostat |
| CN102973530B (zh) * | 2012-12-14 | 2016-08-03 | 贵州信邦制药股份有限公司 | 一种非布索坦双层肠溶片剂及其制备方法 |
| WO2014125504A2 (en) * | 2013-02-18 | 2014-08-21 | Hetero Research Foundation | Pharmaceutical compositions of febuxostat |
| SG11201509738RA (en) * | 2013-05-31 | 2015-12-30 | Takeda Pharmaceuticals Usa Inc | Methods of treatment and compositions with xanthine oxidase inhibitors |
| EP2881116A1 (en) * | 2013-12-05 | 2015-06-10 | Ranbaxy Laboratories Limited | Febuxostat composition |
| AU2015392441A1 (en) * | 2015-04-20 | 2017-11-09 | Twi Biotechnology, Inc. | Formulations containing diacerein and methods of lowering blood levels of uric acid using the same |
| TWI684465B (zh) * | 2015-04-22 | 2020-02-11 | 安成生物科技股份有限公司 | 含雙醋瑞因之製劑及使用其於降低尿酸血中濃度的方法 |
| WO2017100559A1 (en) * | 2015-12-10 | 2017-06-15 | Cogwellin Llc | Controlled release formulations of salicylate-releasing actives |
| CN106279024B (zh) * | 2016-07-19 | 2018-09-14 | 华南理工大学 | 一种黄嘌呤氧化还原酶抑制剂及其制备方法与应用 |
| CN106146419A (zh) * | 2016-08-01 | 2016-11-23 | 沈阳药科大学 | 黄嘌呤氧化酶抑制剂 |
| JP6861726B2 (ja) * | 2016-11-28 | 2021-04-21 | 帝人ファーマ株式会社 | 糖尿病性腎症の治療薬または予防薬 |
| WO2018228440A1 (zh) * | 2017-06-14 | 2018-12-20 | 江苏恒瑞医药股份有限公司 | 一种非布司他控释组合物及其制备方法 |
| CN109721586B (zh) * | 2017-10-27 | 2021-03-02 | 中国医科大学 | 一种5-苄基-3-吡啶基-1h-1,2,4-三唑类化合物及其制备方法和用途 |
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