CL2012002347A1 - Metodo in vitro para el diagnostico de la demencia con cuerpos de lewy (lbd), que comprende determinar en una muestra biológica de un individuo el genotipo de las siguientes alteraciones en el gen de la butirilcolinesterasa o de polimorfismos en desequilibrio de union de los mismos; kit para llevar a cabo dicho método; uso del kit para el diagnóstico de lbd. - Google Patents
Metodo in vitro para el diagnostico de la demencia con cuerpos de lewy (lbd), que comprende determinar en una muestra biológica de un individuo el genotipo de las siguientes alteraciones en el gen de la butirilcolinesterasa o de polimorfismos en desequilibrio de union de los mismos; kit para llevar a cabo dicho método; uso del kit para el diagnóstico de lbd.Info
- Publication number
- CL2012002347A1 CL2012002347A1 CL2012002347A CL2012002347A CL2012002347A1 CL 2012002347 A1 CL2012002347 A1 CL 2012002347A1 CL 2012002347 A CL2012002347 A CL 2012002347A CL 2012002347 A CL2012002347 A CL 2012002347A CL 2012002347 A1 CL2012002347 A1 CL 2012002347A1
- Authority
- CL
- Chile
- Prior art keywords
- lbd
- kit
- polymorphisms
- genotype
- dementia
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- 108010053652 Butyrylcholinesterase Proteins 0.000 title 1
- 206010067889 Dementia with Lewy bodies Diseases 0.000 title 1
- 238000009007 Diagnostic Kit Methods 0.000 title 1
- 201000002832 Lewy body dementia Diseases 0.000 title 1
- 230000004075 alteration Effects 0.000 title 1
- 239000012472 biological sample Substances 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 238000000338 in vitro Methods 0.000 title 1
- 102000054765 polymorphisms of proteins Human genes 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10382042A EP2360280A1 (en) | 2010-02-24 | 2010-02-24 | Genetic marker for the diagnosis of dementia with Lewy bodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2012002347A1 true CL2012002347A1 (es) | 2013-12-13 |
Family
ID=42077915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2012002347A CL2012002347A1 (es) | 2010-02-24 | 2012-08-23 | Metodo in vitro para el diagnostico de la demencia con cuerpos de lewy (lbd), que comprende determinar en una muestra biológica de un individuo el genotipo de las siguientes alteraciones en el gen de la butirilcolinesterasa o de polimorfismos en desequilibrio de union de los mismos; kit para llevar a cabo dicho método; uso del kit para el diagnóstico de lbd. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20130101997A1 (es) |
| EP (2) | EP2360280A1 (es) |
| JP (1) | JP2013520185A (es) |
| KR (2) | KR20130043107A (es) |
| CN (1) | CN102869786B (es) |
| AU (1) | AU2011220065A1 (es) |
| BR (1) | BR112012021260A2 (es) |
| CA (1) | CA2789054A1 (es) |
| CL (1) | CL2012002347A1 (es) |
| IL (1) | IL221313A0 (es) |
| MX (1) | MX2012009506A (es) |
| NZ (1) | NZ602551A (es) |
| RU (1) | RU2012140458A (es) |
| SG (1) | SG183437A1 (es) |
| WO (1) | WO2011104023A1 (es) |
| ZA (1) | ZA201206975B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2360280A1 (en) * | 2010-02-24 | 2011-08-24 | Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol | Genetic marker for the diagnosis of dementia with Lewy bodies |
| US20140249047A1 (en) * | 2011-07-29 | 2014-09-04 | Universitat Autonoma De Barcelona | Genetic marker for the diagnosis of dementia with lewy bodies |
| EP2990800A1 (en) * | 2014-08-29 | 2016-03-02 | Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol | Neprilysin as heartfailure (HF) prognostic marker |
| WO2016164474A1 (en) * | 2015-04-06 | 2016-10-13 | The Trustees Of Columbia University In The City Of New York | Predictive value of combined genetic enzymatic and lipidomic data in disease risk for lewy body disease |
| WO2016180725A1 (en) | 2015-05-08 | 2016-11-17 | Fundació Institut D'investigació En Ciències De La Salut Germans Trias I Pujol | Diagnosis of dementia with lewy bodies |
| EP3091087A1 (en) | 2015-05-08 | 2016-11-09 | Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol | Method for in vitro diagnosis of synucleinopathies using alpha-synuclein gene transcripts |
| EP3385393A1 (de) * | 2017-04-05 | 2018-10-10 | Eckart Schnakenberg | In-vitro-verfahren zur diagnose des risikos einer person zur ausbildung eines aerotoxischen syndroms und kit zur durchführung des verfahrens |
| US12065701B2 (en) | 2018-07-19 | 2024-08-20 | Fundació Institut D'investigació En Ciències De La Salut Germans Trias I Pujol | In vitro method for the diagnosis of synucleinopathies |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6022683A (en) * | 1996-12-16 | 2000-02-08 | Nova Molecular Inc. | Methods for assessing the prognosis of a patient with a neurodegenerative disease |
| GB0323703D0 (en) * | 2003-10-09 | 2003-11-12 | Medical Res Council | Method |
| CA3078084C (en) * | 2007-07-31 | 2023-08-15 | Cerecin Inc. | Use of genomic testing and ketogenic compounds for treatment of reduced cognitive function |
| EP2360280A1 (en) * | 2010-02-24 | 2011-08-24 | Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol | Genetic marker for the diagnosis of dementia with Lewy bodies |
-
2010
- 2010-02-24 EP EP10382042A patent/EP2360280A1/en not_active Withdrawn
-
2011
- 2011-02-24 MX MX2012009506A patent/MX2012009506A/es not_active Application Discontinuation
- 2011-02-24 KR KR1020127029377A patent/KR20130043107A/ko not_active Withdrawn
- 2011-02-24 KR KR1020127024833A patent/KR20130049771A/ko not_active Ceased
- 2011-02-24 NZ NZ602551A patent/NZ602551A/en not_active IP Right Cessation
- 2011-02-24 SG SG2012062063A patent/SG183437A1/en unknown
- 2011-02-24 CN CN201180011143.7A patent/CN102869786B/zh not_active Expired - Fee Related
- 2011-02-24 EP EP11708400.4A patent/EP2539461B1/en not_active Not-in-force
- 2011-02-24 CA CA2789054A patent/CA2789054A1/en not_active Abandoned
- 2011-02-24 BR BR112012021260A patent/BR112012021260A2/pt not_active IP Right Cessation
- 2011-02-24 US US13/578,987 patent/US20130101997A1/en not_active Abandoned
- 2011-02-24 AU AU2011220065A patent/AU2011220065A1/en not_active Abandoned
- 2011-02-24 WO PCT/EP2011/000903 patent/WO2011104023A1/en not_active Ceased
- 2011-02-24 RU RU2012140458/10A patent/RU2012140458A/ru not_active Application Discontinuation
- 2011-02-24 JP JP2012554248A patent/JP2013520185A/ja active Pending
-
2012
- 2012-08-05 IL IL221313A patent/IL221313A0/en unknown
- 2012-08-23 CL CL2012002347A patent/CL2012002347A1/es unknown
- 2012-09-17 ZA ZA2012/06975A patent/ZA201206975B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20130101997A1 (en) | 2013-04-25 |
| KR20130043107A (ko) | 2013-04-29 |
| SG183437A1 (en) | 2012-09-27 |
| IL221313A0 (en) | 2012-10-31 |
| MX2012009506A (es) | 2012-09-12 |
| CN102869786B (zh) | 2014-12-24 |
| RU2012140458A (ru) | 2014-03-27 |
| NZ602551A (en) | 2014-03-28 |
| ZA201206975B (en) | 2015-08-26 |
| BR112012021260A2 (pt) | 2017-11-14 |
| WO2011104023A1 (en) | 2011-09-01 |
| EP2539461A1 (en) | 2013-01-02 |
| CA2789054A1 (en) | 2011-09-01 |
| EP2539461B1 (en) | 2015-01-07 |
| JP2013520185A (ja) | 2013-06-06 |
| CN102869786A (zh) | 2013-01-09 |
| AU2011220065A1 (en) | 2012-10-11 |
| EP2360280A1 (en) | 2011-08-24 |
| KR20130049771A (ko) | 2013-05-14 |
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