CL2012000063A1 - Polipéptido factor ix (fix) o un fragmento del mismo porque comprende la modificación de un aminoácido; vector; célula; método para expresar el polipéptido fix; composición farmacéutica; uso de la composición para tratar enfermedades trombóticas, hemorrágicas y coagulación intravascular diseminada (cid) (div. sol. 1796-07). - Google Patents
Polipéptido factor ix (fix) o un fragmento del mismo porque comprende la modificación de un aminoácido; vector; célula; método para expresar el polipéptido fix; composición farmacéutica; uso de la composición para tratar enfermedades trombóticas, hemorrágicas y coagulación intravascular diseminada (cid) (div. sol. 1796-07).Info
- Publication number
- CL2012000063A1 CL2012000063A1 CL2012000063A CL2012000063A CL2012000063A1 CL 2012000063 A1 CL2012000063 A1 CL 2012000063A1 CL 2012000063 A CL2012000063 A CL 2012000063A CL 2012000063 A CL2012000063 A CL 2012000063A CL 2012000063 A1 CL2012000063 A1 CL 2012000063A1
- Authority
- CL
- Chile
- Prior art keywords
- polypeptide
- fix
- composition
- div
- sol
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102100022641 Coagulation factor IX Human genes 0.000 title abstract 2
- 108010076282 Factor IX Proteins 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- 208000009190 disseminated intravascular coagulation Diseases 0.000 title abstract 2
- 229960004222 factor ix Drugs 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 title abstract 2
- 208000031169 hemorrhagic disease Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000012986 modification Methods 0.000 title abstract 2
- 230000004048 modification Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000001732 thrombotic effect Effects 0.000 title abstract 2
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/644—Coagulation factor IXa (3.4.21.22)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21022—Coagulation factor IXa (3.4.21.22)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Polipéptido factor IX (fix) o un fragmento del mismo porque comprende la modificación de un aminoácido; vector; célula; método para expresar el polipéptido fix; composición farmacéutica; uso de la composición para tratar enfermedades trombóticas, hemorrágicas y coagulación intravascular diseminada (CID) (Div. Sol. 1796-07).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81511306P | 2006-06-19 | 2006-06-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2012000063A1 true CL2012000063A1 (es) | 2012-08-24 |
Family
ID=38834052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2012000063A CL2012000063A1 (es) | 2006-06-19 | 2012-01-09 | Polipéptido factor ix (fix) o un fragmento del mismo porque comprende la modificación de un aminoácido; vector; célula; método para expresar el polipéptido fix; composición farmacéutica; uso de la composición para tratar enfermedades trombóticas, hemorrágicas y coagulación intravascular diseminada (cid) (div. sol. 1796-07). |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8383388B2 (es) |
| EP (4) | EP2084274A2 (es) |
| CL (1) | CL2012000063A1 (es) |
| PE (1) | PE20080339A1 (es) |
| TW (1) | TW200804416A (es) |
| WO (1) | WO2007149406A2 (es) |
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| ES2524974T3 (es) | 2009-06-25 | 2014-12-16 | The University Of North Carolina At Chapel Hill | Moléculas del Factor VII quimérico |
| US12203113B2 (en) | 2009-07-09 | 2025-01-21 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
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-
2007
- 2007-06-15 WO PCT/US2007/014219 patent/WO2007149406A2/en not_active Ceased
- 2007-06-15 TW TW096121694A patent/TW200804416A/zh unknown
- 2007-06-15 EP EP07809648A patent/EP2084274A2/en not_active Withdrawn
- 2007-06-15 EP EP11189834A patent/EP2423306A1/en not_active Withdrawn
- 2007-06-15 EP EP11189837A patent/EP2423307A1/en not_active Withdrawn
- 2007-06-15 US US11/818,985 patent/US8383388B2/en not_active Expired - Fee Related
- 2007-06-15 EP EP11189828A patent/EP2423305A1/en not_active Withdrawn
- 2007-06-19 PE PE2007000780A patent/PE20080339A1/es not_active Application Discontinuation
-
2012
- 2012-01-09 CL CL2012000063A patent/CL2012000063A1/es unknown
- 2012-11-14 US US13/694,290 patent/US20130243855A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2423307A1 (en) | 2012-02-29 |
| WO2007149406A8 (en) | 2008-09-25 |
| US8383388B2 (en) | 2013-02-26 |
| EP2084274A2 (en) | 2009-08-05 |
| WO2007149406A3 (en) | 2008-07-10 |
| WO2007149406A2 (en) | 2007-12-27 |
| PE20080339A1 (es) | 2008-06-06 |
| US20130243855A1 (en) | 2013-09-19 |
| US20080102115A1 (en) | 2008-05-01 |
| WO2007149406A9 (en) | 2008-03-13 |
| EP2423306A1 (en) | 2012-02-29 |
| TW200804416A (en) | 2008-01-16 |
| EP2423305A1 (en) | 2012-02-29 |
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