CL2007002163A1 - Compuestos derivados de 2-fenilindol, antagonistas del receptor de prostaglandina d2; composicion farmaceutica; y uso para tratar enfermedades alergicas tales como asma bronquial y rinitis alergica, broncoconstriccion, epoc, accidente cerebrovascular - Google Patents

Compuestos derivados de 2-fenilindol, antagonistas del receptor de prostaglandina d2; composicion farmaceutica; y uso para tratar enfermedades alergicas tales como asma bronquial y rinitis alergica, broncoconstriccion, epoc, accidente cerebrovascular

Info

Publication number: CL2007002163A1
Authority: CL; Chile
Prior art keywords: prostaglandina; broncoconstriction; phenylindol; copd; antagonists
Prior art date: 2006-07-25

Application number

CL200702163A

Other languages

English (en)

Inventor

Zhaoxia Reiling Stephan N Yang

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-07-25

Filing date

2007-07-24

Publication date

2008-02-08

2007-07-24 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2008-02-08 Publication of CL2007002163A1 publication Critical patent/CL2007002163A1/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pulmonology (AREA)
Immunology (AREA)
Ophthalmology & Optometry (AREA)
Dermatology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Otolaryngology (AREA)
Pain & Pain Management (AREA)
Transplantation (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Indole Compounds (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)

CL200702163A 2006-07-25 2007-07-24 Compuestos derivados de 2-fenilindol, antagonistas del receptor de prostaglandina d2; composicion farmaceutica; y uso para tratar enfermedades alergicas tales como asma bronquial y rinitis alergica, broncoconstriccion, epoc, accidente cerebrovascular CL2007002163A1 (es)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US82030106P	2006-07-25	2006-07-25
US82029906P	2006-07-25	2006-07-25
US82030206P	2006-07-25	2006-07-25

Publications (1)

Publication Number	Publication Date
CL2007002163A1 true CL2007002163A1 (es)	2008-02-08

Family

ID=38610820

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CL200702163A CL2007002163A1 (es)	2006-07-25	2007-07-24	Compuestos derivados de 2-fenilindol, antagonistas del receptor de prostaglandina d2; composicion farmaceutica; y uso para tratar enfermedades alergicas tales como asma bronquial y rinitis alergica, broncoconstriccion, epoc, accidente cerebrovascular

Country Status (25)

Country	Link
US (1)	US20090176804A1 (es)
EP (1)	EP2066628B1 (es)
JP (1)	JP2009544721A (es)
KR (1)	KR20090039735A (es)
AR (1)	AR062051A1 (es)
AT (1)	ATE485270T1 (es)
AU (1)	AU2007276885A1 (es)
BR (1)	BRPI0714554A2 (es)
CA (1)	CA2659055A1 (es)
CL (1)	CL2007002163A1 (es)
CO (1)	CO6190511A2 (es)
CR (1)	CR10577A (es)
DE (1)	DE602007010010D1 (es)
DK (1)	DK2066628T3 (es)
EC (1)	ECSP099087A (es)
GT (1)	GT200900016A (es)
IL (1)	IL196587A0 (es)
MA (1)	MA30643B1 (es)
MX (1)	MX2009000830A (es)
NO (1)	NO20090862L (es)
PE (1)	PE20080549A1 (es)
PT (1)	PT2066628E (es)
TN (1)	TNSN08515A1 (es)
TW (1)	TW200821286A (es)
WO (1)	WO2008014186A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPWO2009072576A1 (ja) *	2007-12-04	2011-04-28	サッポロビール株式会社	骨形成促進剤
RU2539185C2 (ru) *	2008-11-17	2015-01-20	Ф.Хоффманн-Ля Рош Аг	Нафтилуксусные кислоты
US8697869B2 (en)	2010-03-22	2014-04-15	Actelion Pharmaceuticals Ltd.	3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9H-carbazole derivatives and their use as prostaglandin D2 receptor modulators
SG193902A1 (en)	2011-04-14	2013-11-29	Actelion Pharmaceuticals Ltd	7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin d2 receptor modulators
WO2014066568A1 (en)	2012-10-24	2014-05-01	Winthrop-University Hospital	Non-invasive biomarker to identify subjects at risk of preterm delivery
JP2015089886A (ja) *	2013-11-06	2015-05-11	国立大学法人名古屋大学	嵩高い置換基を有する化合物を用いた植物成長調整剤
UA117780C2 (uk)	2014-03-17	2018-09-25	Ідорсія Фармасьютікалз Лтд	Похідні азаіндолоцтової кислоти та їх застосування як модуляторів рецепторів простагландину d2
TW201620909A (zh)	2014-03-18	2016-06-16	艾克泰聯製藥有限公司	氮雜吲哚乙酸衍生物及彼等作為前列腺素ｄ２受體調節劑之用途
MX379014B (es)	2015-09-15	2025-03-10	Idorsia Pharmaceuticals Ltd	Formas cristalinas.
CA3075688A1 (en)	2017-09-13	2019-03-21	Progenity, Inc.	Preeclampsia biomarkers and related systems and methods
US11884645B2 (en)	2018-03-02	2024-01-30	Inflazome Limited	Sulfonyl acetamides as NLRP3 inhibitors
WO2019166632A1 (en)	2018-03-02	2019-09-06	Inflazome Limited	Novel compounds
WO2019166627A1 (en)	2018-03-02	2019-09-06	Inflazome Limited	Novel compounds
WO2019166629A1 (en) *	2018-03-02	2019-09-06	Inflazome Limited	Novel compounds
EP3759073A1 (en)	2018-03-02	2021-01-06	Inflazome Limited	Sulfonamide derivates as nlrp3 inhibitors
US12202790B2 (en)	2018-05-09	2025-01-21	Glucox Biotech Ab	Sulfonamide derivatives having selective Nox inhibiting activity
EP4070113A4 (en)	2019-12-04	2023-12-20	Biora Therapeutics, Inc.	ASSESSMENT OF PREECAMPSIA USING FREE AND DISSOCIATE PLACENTAL GROWTH FACTOR ASSAYS
CN111333516B (zh) *	2020-04-14	2022-09-06	国药集团化学试剂有限公司	一种2-氯-5-溴硝基苯的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DOP2006000016A (es) *	2005-01-26	2006-07-31	Aventis Pharma Inc	2-fenil-indoles como antagonistas del receptor de la prostaglandina d2.

2007
- 2007-07-20 AT AT07799729T patent/ATE485270T1/de active
- 2007-07-20 DK DK07799729.4T patent/DK2066628T3/da active
- 2007-07-20 PT PT07799729T patent/PT2066628E/pt unknown
- 2007-07-20 AU AU2007276885A patent/AU2007276885A1/en not_active Abandoned
- 2007-07-20 JP JP2009521914A patent/JP2009544721A/ja not_active Abandoned
- 2007-07-20 WO PCT/US2007/073945 patent/WO2008014186A1/en not_active Ceased
- 2007-07-20 CA CA002659055A patent/CA2659055A1/en not_active Abandoned
- 2007-07-20 KR KR1020097001687A patent/KR20090039735A/ko not_active Abandoned
- 2007-07-20 DE DE602007010010T patent/DE602007010010D1/de active Active
- 2007-07-20 BR BRPI0714554-3A patent/BRPI0714554A2/pt not_active IP Right Cessation
- 2007-07-20 EP EP07799729A patent/EP2066628B1/en active Active
- 2007-07-20 MX MX2009000830A patent/MX2009000830A/es active IP Right Grant
- 2007-07-23 PE PE2007000951A patent/PE20080549A1/es not_active Application Discontinuation
- 2007-07-24 AR ARP070103291A patent/AR062051A1/es not_active Application Discontinuation
- 2007-07-24 CL CL200702163A patent/CL2007002163A1/es unknown
- 2007-07-25 TW TW096127005A patent/TW200821286A/zh unknown
2008
- 2008-12-12 TN TNP2008000515A patent/TNSN08515A1/en unknown
2009
- 2009-01-15 CO CO09002745A patent/CO6190511A2/es not_active Application Discontinuation
- 2009-01-19 IL IL196587A patent/IL196587A0/en unknown
- 2009-01-21 CR CR10577A patent/CR10577A/es not_active Application Discontinuation
- 2009-01-22 US US12/357,725 patent/US20090176804A1/en not_active Abandoned
- 2009-01-23 GT GT200900016A patent/GT200900016A/es unknown
- 2009-01-23 EC EC2009009087A patent/ECSP099087A/es unknown
- 2009-02-13 MA MA31635A patent/MA30643B1/fr unknown
- 2009-02-24 NO NO20090862A patent/NO20090862L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
PT2066628E (pt)	2010-12-31
JP2009544721A (ja)	2009-12-17
ATE485270T1 (de)	2010-11-15
MX2009000830A (es)	2009-02-03
BRPI0714554A2 (pt)	2013-05-07
TNSN08515A1 (en)	2010-04-14
AU2007276885A1 (en)	2008-01-31
TW200821286A (en)	2008-05-16
CO6190511A2 (es)	2010-08-19
NO20090862L (no)	2009-02-24
ECSP099087A (es)	2009-02-27
CR10577A (es)	2009-03-20
WO2008014186A1 (en)	2008-01-31
GT200900016A (es)	2010-10-13
KR20090039735A (ko)	2009-04-22
DE602007010010D1 (de)	2010-12-02
PE20080549A1 (es)	2008-06-20
AR062051A1 (es)	2008-08-10
MA30643B1 (fr)	2009-08-03
DK2066628T3 (da)	2011-02-07
EP2066628B1 (en)	2010-10-20
US20090176804A1 (en)	2009-07-09
CA2659055A1 (en)	2008-01-31
IL196587A0 (en)	2009-11-18
EP2066628A1 (en)	2009-06-10

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