BRPI1011830A2 - microencapsulação de substância bioativas e métodos de preparação da mesma - Google Patents
microencapsulação de substância bioativas e métodos de preparação da mesmaInfo
- Publication number
- BRPI1011830A2 BRPI1011830A2 BRPI1011830A BRPI1011830A BRPI1011830A2 BR PI1011830 A2 BRPI1011830 A2 BR PI1011830A2 BR PI1011830 A BRPI1011830 A BR PI1011830A BR PI1011830 A BRPI1011830 A BR PI1011830A BR PI1011830 A2 BRPI1011830 A2 BR PI1011830A2
- Authority
- BR
- Brazil
- Prior art keywords
- microencapsulation
- preparation
- methods
- bioactive substances
- bioactive
- Prior art date
Links
- 230000000975 bioactive effect Effects 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A21—BAKING; EDIBLE DOUGHS
- A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
- A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
- A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
- A21D2/14—Organic oxygen compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/06—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/40—Colouring or decolouring of foods
- A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
- A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
- A23L5/44—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
- A23P10/35—Encapsulation of particles, e.g. foodstuff additives with oils, lipids, monoglycerides or diglycerides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Preparation And Processing Of Foods (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Formation And Processing Of Food Products (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16372809P | 2009-03-26 | 2009-03-26 | |
| PCT/US2010/028432 WO2010111347A2 (en) | 2009-03-26 | 2010-03-24 | Microencapsulation of bioactive substances and methods of making the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1011830A2 true BRPI1011830A2 (pt) | 2016-09-13 |
Family
ID=42781836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1011830A BRPI1011830A2 (pt) | 2009-03-26 | 2010-03-24 | microencapsulação de substância bioativas e métodos de preparação da mesma |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9445613B2 (pt) |
| EP (1) | EP2410879B8 (pt) |
| JP (1) | JP5923443B2 (pt) |
| CN (1) | CN102427740B (pt) |
| BR (1) | BRPI1011830A2 (pt) |
| ES (1) | ES2732833T3 (pt) |
| WO (1) | WO2010111347A2 (pt) |
Families Citing this family (46)
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|---|---|---|---|---|
| US8968721B2 (en) | 2005-12-28 | 2015-03-03 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
| EP1973406B1 (en) | 2005-12-28 | 2014-03-12 | Advanced Bionutrition Corporation | A delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form |
| JP5285617B2 (ja) | 2006-12-18 | 2013-09-11 | アドバンスド バイオニュートリション コーポレーション | 生きたプロバイオティクスを含む乾燥食物製品 |
| US8778384B2 (en) | 2008-03-24 | 2014-07-15 | Advanced Bionutrition Corporation | Compositions and methods for encapsulating vaccines for the oral vaccination and boostering of fish and other animals |
| US7998502B2 (en) * | 2008-03-24 | 2011-08-16 | Advanced Bionutrition Corp. | Encapsulated vaccines for the oral vaccination and boostering of fish and other animals |
| EP3266448B1 (en) | 2009-03-27 | 2022-02-16 | Intervet International B.V. | Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish |
| MY157343A (en) | 2009-05-26 | 2016-05-31 | Advanced Bionutrition Corp | Stable dry powder composition comprising biologically active microorganisms and/or bioactive materials and methods of making |
| US9504750B2 (en) | 2010-01-28 | 2016-11-29 | Advanced Bionutrition Corporation | Stabilizing composition for biological materials |
| ES2639397T3 (es) | 2010-01-28 | 2017-10-26 | Advanced Bionutrition Corporation | Composición vítrea seca que comprende un material bioactivo |
| BR112013003244B1 (pt) | 2010-08-13 | 2018-07-17 | Advanced Bionutrition Corp | composição seca estabilizante para material biológico, seu método de preparação, e formulação de carreamento oral |
| CA2861956A1 (en) * | 2012-01-20 | 2013-07-25 | Milk Specialties Company D/B/A Milk Specialties Global | Method of instantizing amino acids |
| JP6491102B2 (ja) | 2012-11-29 | 2019-03-27 | プロゲル プロプライアタリー リミティド | プロバイオティクス、架橋性試薬、変性タンパク質、ポリオール可塑剤及びトレハロースを含む微小粒子 |
| AU2013351919B2 (en) * | 2012-11-29 | 2018-09-27 | Progel Pty Ltd | A microparticle composition comprising a probiotic, cross-linkable reagent and an emulsion containing a hydrophobic active |
| US11602542B2 (en) * | 2014-07-31 | 2023-03-14 | Amorphical Ltd. | Non-aqueous liquid and semi-solid formulations of amorphous calcium carbonate |
| SG11201700968PA (en) * | 2014-08-11 | 2017-03-30 | Perora Gmbh | Formulation comprising particles |
| RU2690672C2 (ru) | 2014-08-11 | 2019-06-05 | Перора Гмбх | Способ обеспечения чувства сытости |
| JP6867305B2 (ja) * | 2015-05-20 | 2021-04-28 | キヤノン ユー.エス. ライフ サイエンシズ, インコーポレイテッドCanon U.S. Life Sciences, Inc. | 磁性キトサン微粒子を使用するポリメラーゼ連鎖反応に対するシングルステップdna調製 |
| US10851399B2 (en) | 2015-06-25 | 2020-12-01 | Native Microbials, Inc. | Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon |
| US10632157B2 (en) | 2016-04-15 | 2020-04-28 | Ascus Biosciences, Inc. | Microbial compositions and methods of use for improving fowl production |
| TW201713775A (zh) | 2015-06-25 | 2017-04-16 | 亞斯科生物科學公司 | 用於自複雜的異源群集中分析微生物品系、預測及識別其機能性關係及交互作用,且依據前述選擇並合成微生物系集之方法、裝置及系統 |
| US9938558B2 (en) | 2015-06-25 | 2018-04-10 | Ascus Biosciences, Inc. | Methods, apparatuses, and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon |
| US11234935B2 (en) | 2015-07-07 | 2022-02-01 | Perora Gmbh | Method of inducing satiety |
| PL3328215T3 (pl) | 2015-07-29 | 2021-12-13 | Advanced Bionutrition Corp. | Stabilne suche kompozycje probiotyczne do specjalnych zastosowań dietetycznych |
| EP3181683A1 (en) | 2015-12-16 | 2017-06-21 | University College Cork - National University of Ireland, Cork | A method of enhancing the survival and recovery of certain strains of bacteria |
| CN105560211B (zh) * | 2015-12-30 | 2019-06-14 | 大连医诺生物股份有限公司 | 优化包埋的微囊制剂 |
| CN105663081B (zh) * | 2015-12-30 | 2019-08-02 | 大连医诺生物股份有限公司 | 微囊化β-丙氨酸 |
| CA3010505A1 (en) | 2016-01-07 | 2017-07-13 | Ascus Biosciences, Inc. | Methods for improving milk production by administration of microbial consortia |
| US20190099371A1 (en) * | 2016-03-24 | 2019-04-04 | Basf Se | Multiphase active substance preparations |
| CA3020833A1 (en) | 2016-04-15 | 2017-10-19 | Ascus Biosciences, Inc. | Methods for improving agricultural production of fowl by administration of microbial consortia or purified strains thereof |
| CN110366596A (zh) | 2016-12-28 | 2019-10-22 | 埃斯库斯生物科技股份公司 | 用于对复杂异质群落中的完整微生物株系进行分析、确定其功能关系及相互作用以及基于此来识别和合成生物活性改性剂的方法、设备和系统 |
| CN110352250A (zh) | 2016-12-28 | 2019-10-18 | 埃斯库斯生物科技股份公司 | 用于通过示踪剂分析法对复杂异质群落进行微生物株系分析、确定其功能关系及相互作用以及合成包括给药微生物群集和接种微生物群集的微生物群集的方法、设备和系统 |
| EP3363429A1 (en) * | 2017-02-20 | 2018-08-22 | DSM IP Assets B.V. | Process for the production of coated particles |
| NZ755788A (en) * | 2017-02-20 | 2022-05-27 | Dsm Ip Assets Bv | Process for producing coated particles |
| WO2018201049A1 (en) | 2017-04-28 | 2018-11-01 | Ascus Biosciences, Inc. | Methods for supporting grain intensive and/or energy intensive diets in ruminants with a synthetic bioensemble of microbes |
| EP3624784A1 (en) * | 2017-05-19 | 2020-03-25 | DSM IP Assets B.V. | Solid particles |
| US11825862B2 (en) | 2017-10-18 | 2023-11-28 | Native Microbials, Inc. | Fowl production by administration of a synthetic bioensemble of microbes or purified strains thereof |
| CN111447837A (zh) * | 2017-11-03 | 2020-07-24 | 阿彻丹尼尔斯米德兰德公司 | 生产用于反刍动物的囊化氨基酸的方法 |
| CN107811298B (zh) * | 2017-12-01 | 2021-02-19 | 浙江新和成股份有限公司 | 一种水溶性营养素微胶囊及其制备方法 |
| CN109619536A (zh) * | 2018-10-18 | 2019-04-16 | 山东海能生物工程有限公司 | 一种25-羟基维生素d3微囊粉及其制备方法 |
| US10993459B2 (en) | 2019-09-23 | 2021-05-04 | Ralph Yoder | Method for unlocking bioactive proteins |
| CN110777022B (zh) * | 2019-11-11 | 2021-10-22 | 广州立白企业集团有限公司 | 一种包裹型生物酶粒子及其制备方法 |
| CA3166211A1 (en) | 2020-02-10 | 2021-08-19 | Native Microbials, Inc. | Microbial compositions and methods of use for canine enteropathy and dysbiosis |
| US20230080017A1 (en) | 2020-02-19 | 2023-03-16 | Zantebio Limited | Coated microcapsules and methods for the production thereof |
| EP4178373A1 (en) * | 2020-11-10 | 2023-05-17 | Firmenich SA | Extruded particle |
| CN114343214B (zh) * | 2021-12-07 | 2022-12-16 | 华南理工大学 | 一种硫酸软骨素-壳聚糖多层修饰的甜菜红素脂质体及其制备方法 |
| AU2023288402A1 (en) * | 2022-06-24 | 2025-01-16 | Advanced Bionutrition Corp. | Double-layer coated microparticles and preparation thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JPS56156212A (en) | 1980-05-08 | 1981-12-02 | Eisai Co Ltd | Surface treating method of soft capsule agent |
| JPS60118153A (ja) * | 1983-11-30 | 1985-06-25 | Takeda Chem Ind Ltd | 強化精米および精麦の製造法 |
| KR870008536A (ko) * | 1986-03-17 | 1987-10-19 | 우다다 가쓰히로 | 오일 또는 지방 피복물질 및 이의 제조방법 |
| JPS63173568A (ja) | 1987-01-14 | 1988-07-18 | Nippon Oil & Fats Co Ltd | 2重被覆粉末油脂 |
| JPH0791186B2 (ja) * | 1987-06-25 | 1995-10-04 | 川崎化成工業株式会社 | L−アスコルビン酸製剤 |
| JP2987165B2 (ja) | 1989-01-27 | 1999-12-06 | 武田薬品工業株式会社 | 被覆製剤およびその用途 |
| US5258132A (en) | 1989-11-15 | 1993-11-02 | Lever Brothers Company, Division Of Conopco, Inc. | Wax-encapsulated particles |
| WO1992011084A1 (en) * | 1990-12-17 | 1992-07-09 | Redding Bruce K Jr | Microencapsulated sweeteners for use in baked goods |
| JP2968089B2 (ja) * | 1991-04-25 | 1999-10-25 | 鐘紡株式会社 | 被覆用素材及びそれを用いた腸溶性造粒物 |
| US5789014A (en) | 1995-12-25 | 1998-08-04 | Shin-Etsu Chemical Co., Ltd. | Method of manufacturing a solid preparation coated with non-solvent coating |
| DK0824000T3 (da) | 1996-08-13 | 2003-02-24 | Nestle Sa | Dispergerbart bindemiddel med et tolags overtræk |
| JPH10203965A (ja) | 1997-01-28 | 1998-08-04 | Takeda Chem Ind Ltd | 被覆製剤の製造法 |
| JP2000026283A (ja) | 1998-07-10 | 2000-01-25 | Nisshin Oil Mills Ltd:The | 油性組成物を含有した粉末組成物 |
| FR2787322B1 (fr) * | 1998-12-18 | 2002-10-18 | Galderma Res & Dev | Emulsion huile-dans-eau comprenant un agent actif micronise et un systeme emulsionnant approprie |
| US7838037B2 (en) * | 1999-11-17 | 2010-11-23 | Tagra Biotechnologies Ltd. | Method of microencapsulation |
| US6887493B2 (en) | 2000-10-25 | 2005-05-03 | Adi Shefer | Multi component controlled release system for oral care, food products, nutraceutical, and beverages |
| KR100814625B1 (ko) * | 2001-06-28 | 2008-03-18 | 모리시타 진탄 가부시키가이샤 | 살아 있는 세포 또는 조직을 포함하는 캡슐 |
| US6974592B2 (en) * | 2002-04-11 | 2005-12-13 | Ocean Nutrition Canada Limited | Encapsulated agglomeration of microcapsules and method for the preparation thereof |
| WO2004016509A2 (en) * | 2002-08-14 | 2004-02-26 | E.I. Du Pont De Nemours And Company | Food partical encapsulation preserving volatiles and preventing oxidation |
| JP3688279B2 (ja) | 2003-08-01 | 2005-08-24 | 森下仁丹株式会社 | 耐熱性カプセルおよびその製造方法 |
| US20070042184A1 (en) | 2003-08-22 | 2007-02-22 | Danisco A/S | Microcapsules |
| US9247765B2 (en) * | 2004-01-14 | 2016-02-02 | Omniactive Health Technologies Limited | Stable beadlets of lipophilic nutrients |
| ITMI20041820A1 (it) * | 2004-09-24 | 2004-12-24 | Ascor Chimici Srl | Composizione in micro-pellets a rilascio controllato di sostanze fisiologicamente attive, procedimento di preparazione e relativo impiego nel settore zootecnico. |
| ATE515198T1 (de) * | 2005-05-18 | 2011-07-15 | Dsm Ip Assets Bv | Zusammensetzung für die enterale verabreichung von mikroorganismen |
| KR100708810B1 (ko) | 2005-07-29 | 2007-04-17 | 서울향료(주) | 난황, 난백 및 대두단백을 이용한 마이크로캡슐 및 그의제조방법 |
| MX2008002023A (es) * | 2005-08-11 | 2008-04-08 | Harvard College | Metodos y composiciones para secar formas celulares. |
| US7803413B2 (en) * | 2005-10-31 | 2010-09-28 | General Mills Ip Holdings Ii, Llc. | Encapsulation of readily oxidizable components |
| JP5979697B2 (ja) * | 2006-06-05 | 2016-08-24 | ディーエスエム ニュートリショナル プロダクツ アーゲーDSM Nutritional Products AG | 改善された殻を有するマイクロカプセル |
-
2010
- 2010-03-24 EP EP10756764.6A patent/EP2410879B8/en active Active
- 2010-03-24 CN CN201080021419.5A patent/CN102427740B/zh active Active
- 2010-03-24 JP JP2012502195A patent/JP5923443B2/ja not_active Expired - Fee Related
- 2010-03-24 WO PCT/US2010/028432 patent/WO2010111347A2/en not_active Ceased
- 2010-03-24 ES ES10756764T patent/ES2732833T3/es active Active
- 2010-03-24 BR BRPI1011830A patent/BRPI1011830A2/pt not_active IP Right Cessation
- 2010-03-24 US US13/260,388 patent/US9445613B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010111347A3 (en) | 2011-01-13 |
| US20120058195A1 (en) | 2012-03-08 |
| US9445613B2 (en) | 2016-09-20 |
| ES2732833T3 (es) | 2019-11-26 |
| EP2410879A4 (en) | 2014-11-19 |
| EP2410879A2 (en) | 2012-02-01 |
| JP5923443B2 (ja) | 2016-05-24 |
| CN102427740B (zh) | 2016-02-03 |
| JP2012521757A (ja) | 2012-09-20 |
| WO2010111347A2 (en) | 2010-09-30 |
| EP2410879B8 (en) | 2019-08-14 |
| CN102427740A (zh) | 2012-04-25 |
| EP2410879B1 (en) | 2019-05-08 |
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| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
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| B15K | Others concerning applications: alteration of classification |
Ipc: A23L 33/16 (2016.01), A21D 2/14 (2006.0 |