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BRPI1007399A2 - Formulações de emulsão narcótica para o tratamento de dor de câncer - Google Patents

Formulações de emulsão narcótica para o tratamento de dor de câncer

Info

Publication number
BRPI1007399A2
BRPI1007399A2 BRPI1007399-0A BRPI1007399A BRPI1007399A2 BR PI1007399 A2 BRPI1007399 A2 BR PI1007399A2 BR PI1007399 A BRPI1007399 A BR PI1007399A BR PI1007399 A2 BRPI1007399 A2 BR PI1007399A2
Authority
BR
Brazil
Prior art keywords
cancer pain
emulsion formulations
pain treatment
narcotic emulsion
narcotic
Prior art date
Application number
BRPI1007399-0A
Other languages
English (en)
Inventor
Kiichiro Nabeta
Toru Hibi
Original Assignee
Teikoku Pharma Usa Inc
Techno Guard Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Pharma Usa Inc, Techno Guard Co Ltd filed Critical Teikoku Pharma Usa Inc
Publication of BRPI1007399A2 publication Critical patent/BRPI1007399A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4468Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI1007399-0A 2009-02-26 2010-01-11 Formulações de emulsão narcótica para o tratamento de dor de câncer BRPI1007399A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15585309P 2009-02-26 2009-02-26
PCT/US2010/020645 WO2010098897A1 (en) 2009-02-26 2010-01-11 Narcotic emulsion formulations for treatment of cancer pain

Publications (1)

Publication Number Publication Date
BRPI1007399A2 true BRPI1007399A2 (pt) 2015-08-25

Family

ID=42631520

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1007399-0A BRPI1007399A2 (pt) 2009-02-26 2010-01-11 Formulações de emulsão narcótica para o tratamento de dor de câncer

Country Status (16)

Country Link
US (2) US8871791B2 (pt)
EP (1) EP2400838B1 (pt)
JP (2) JP5619780B2 (pt)
KR (2) KR101564058B1 (pt)
CN (1) CN102333443A (pt)
AU (1) AU2010218424B2 (pt)
BR (1) BRPI1007399A2 (pt)
CA (1) CA2752639A1 (pt)
EA (1) EA201190135A1 (pt)
IL (1) IL213940A0 (pt)
MX (1) MX2011007885A (pt)
NZ (1) NZ594486A (pt)
SG (1) SG174157A1 (pt)
TW (1) TWI446932B (pt)
WO (1) WO2010098897A1 (pt)
ZA (1) ZA201104963B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090286832A1 (en) * 2008-05-15 2009-11-19 Kiichiro Nabeta Narcotic emulsion formulations for treatment of surgical pain
WO2010098897A1 (en) * 2009-02-26 2010-09-02 Teikoku Pharma Usa, Inc. Narcotic emulsion formulations for treatment of cancer pain
US9155734B2 (en) 2012-03-07 2015-10-13 Mallinckrodt Llc Stability of hydromorphone hydrochloride solutions
MX361779B (es) * 2012-03-07 2018-12-17 Piramal Critical Care Ltd Estabilidad mejorada de soluciones de clorhidrato de hidromorfona.
WO2018131620A1 (ja) * 2017-01-12 2018-07-19 テクノガード株式会社 薬物含有脂肪乳剤およびその製造方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
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JPH0647533B2 (ja) * 1984-08-10 1994-06-22 裕 水島 4−ビフエニリル酢酸系化合物含有脂肪乳剤
JPS6211915A (ja) 1985-07-10 1987-01-20 Hitachi Ltd 電力系統の無効電力補償装置
US4816247A (en) * 1985-09-11 1989-03-28 American Cyanamid Company Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs
ES2138130T3 (es) * 1995-10-28 2000-01-01 Braun Melsungen Ag Composicion farmaceutica que contiene un anestesico local y/o un analgesico de accion central.
GB9721746D0 (en) * 1997-10-15 1997-12-10 Panos Therapeutics Limited Compositions
US6455525B1 (en) 1999-11-04 2002-09-24 Cephalon, Inc. Heterocyclic substituted pyrazolones
US7211596B2 (en) 2001-05-11 2007-05-01 Mitsubishi Pharma Corporation Stable high-concentration injection containing pyrazolone derivative
JP2004043479A (ja) * 2002-07-11 2004-02-12 Taiho Yakuhin Kogyo Kk 経鼻吸収用組成物
AU2003285864C1 (en) 2002-10-08 2010-07-01 Rinat Neuroscience Corp. Methods for treating post-surgical pain by administering a nerve growth factor antagonist and compositions containing the same
WO2005112926A1 (en) * 2004-05-17 2005-12-01 Pharmacofore, Inc. Compositions and methods for treating or preventing pain
DE102004025357B4 (de) 2004-05-19 2007-03-29 Beiersdorf Ag Emulsionskonzentrat mit wasserlöslichen und öllöslichen Polymeren und kosmetische Zubereitung enthaltend Emulsionskonzentrat sowie ein Verfahren zu dessen Herstellung und dessen Verwendung
US7871632B2 (en) * 2004-07-12 2011-01-18 Adventrx Pharmaceuticals, Inc. Compositions for delivering highly water soluble drugs
US20070087977A1 (en) 2004-11-16 2007-04-19 Wendye Robbins Methods and compositions for treating pain
US20060189682A1 (en) 2005-02-02 2006-08-24 Payne Joseph E Water soluble prodrugs of COX-2 inhibitors
JP4929158B2 (ja) * 2005-03-14 2012-05-09 株式会社大塚製薬工場 難水溶性薬物を含有する医薬組成物
EP1928414A2 (en) * 2005-04-22 2008-06-11 Novacardia, Inc. Production of emulsions for intravenous injection of water-insoluble pharmaceutical compositions
US8158152B2 (en) 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
US8252328B2 (en) 2006-01-06 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
EP1976521B1 (en) 2006-01-25 2015-03-11 Insys Therapeutics, Inc. Sublingual fentanyl spray
WO2007103185A2 (en) 2006-03-01 2007-09-13 University Of Tennessee Research Foundation Sustained release dosage forms of analagesic medications
WO2008133952A2 (en) 2007-04-24 2008-11-06 Cephalon, Inc. Transmucosal treatment with fentanyl in patients with mucositis
CN101066245A (zh) 2007-05-25 2007-11-07 朱芳海 一种口服乳剂及其制备方法
US7779136B2 (en) 2007-11-01 2010-08-17 Telefonaktiebolaget L M Ericsson (Publ) Secure neighbor discovery between hosts connected through a proxy
CN101199525A (zh) 2007-12-15 2008-06-18 王鸿英 一种丙泊酚静脉混合注射剂及其制备方法
US20090286832A1 (en) 2008-05-15 2009-11-19 Kiichiro Nabeta Narcotic emulsion formulations for treatment of surgical pain
WO2010098897A1 (en) * 2009-02-26 2010-09-02 Teikoku Pharma Usa, Inc. Narcotic emulsion formulations for treatment of cancer pain

Also Published As

Publication number Publication date
EP2400838B1 (en) 2016-05-11
AU2010218424A1 (en) 2011-09-01
JP2012519167A (ja) 2012-08-23
US20150141461A1 (en) 2015-05-21
CA2752639A1 (en) 2010-09-02
WO2010098897A1 (en) 2010-09-02
KR101564058B1 (ko) 2015-10-29
ZA201104963B (en) 2012-11-28
TWI446932B (zh) 2014-08-01
US20100216842A1 (en) 2010-08-26
US9427435B2 (en) 2016-08-30
IL213940A0 (en) 2011-07-31
KR20140041944A (ko) 2014-04-04
JP2014205680A (ja) 2014-10-30
TW201038297A (en) 2010-11-01
EP2400838A4 (en) 2012-08-01
CN102333443A (zh) 2012-01-25
EP2400838A1 (en) 2012-01-04
US8871791B2 (en) 2014-10-28
KR20110099747A (ko) 2011-09-08
SG174157A1 (en) 2011-10-28
JP5978248B2 (ja) 2016-08-24
MX2011007885A (es) 2011-12-08
EA201190135A1 (ru) 2012-07-30
AU2010218424B2 (en) 2014-02-13
JP5619780B2 (ja) 2014-11-05
NZ594486A (en) 2013-07-26

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.