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BRPI0923500A2 - uso e composição farmacêutica compreendendo agonista ou modulador do receptor s1p, e kit. - Google Patents

uso e composição farmacêutica compreendendo agonista ou modulador do receptor s1p, e kit.

Info

Publication number
BRPI0923500A2
BRPI0923500A2 BRPI0923500-0A BRPI0923500A BRPI0923500A2 BR PI0923500 A2 BRPI0923500 A2 BR PI0923500A2 BR PI0923500 A BRPI0923500 A BR PI0923500A BR PI0923500 A2 BRPI0923500 A2 BR PI0923500A2
Authority
BR
Brazil
Prior art keywords
modulator
kit
composition
receptor agonist
pharmaceutical use
Prior art date
Application number
BRPI0923500-0A
Other languages
English (en)
Inventor
Schmouder Robert
Dumortier Thomas
David Olivier
Looby Michael
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41667217&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0923500(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0923500A2 publication Critical patent/BRPI0923500A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0923500-0A 2008-12-22 2009-12-21 uso e composição farmacêutica compreendendo agonista ou modulador do receptor s1p, e kit. BRPI0923500A2 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US13967208P 2008-12-22 2008-12-22
US61/139,672 2008-12-22
US21853009P 2009-06-19 2009-06-19
US61/218,530 2009-06-19
US24671509P 2009-09-29 2009-09-29
US61/246,715 2009-09-29
PCT/US2009/068888 WO2010075239A1 (en) 2008-12-22 2009-12-21 Dosage regimen for a s1p receptor agonist

Publications (1)

Publication Number Publication Date
BRPI0923500A2 true BRPI0923500A2 (pt) 2018-05-29

Family

ID=41667217

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0923500-0A BRPI0923500A2 (pt) 2008-12-22 2009-12-21 uso e composição farmacêutica compreendendo agonista ou modulador do receptor s1p, e kit.

Country Status (43)

Country Link
US (12) US20110257133A1 (pt)
EP (7) EP3120844A1 (pt)
JP (7) JP2012513401A (pt)
KR (1) KR101347919B1 (pt)
CN (1) CN102264359A (pt)
AR (1) AR074826A1 (pt)
AU (1) AU2009330176C9 (pt)
BR (1) BRPI0923500A2 (pt)
CA (1) CA2747802C (pt)
CL (2) CL2011001529A1 (pt)
CO (1) CO6390117A2 (pt)
CR (1) CR20110274A (pt)
CU (1) CU20110136A7 (pt)
CY (4) CY1116990T1 (pt)
DK (4) DK3409274T3 (pt)
EA (1) EA201100978A1 (pt)
EC (1) ECSP11011222A (pt)
ES (4) ES3017254T3 (pt)
FI (2) FI4098256T3 (pt)
FR (2) FR20C1060I1 (pt)
HN (1) HN2011001759A (pt)
HR (4) HRP20151190T1 (pt)
HU (6) HUE048717T4 (pt)
IL (3) IL213170A0 (pt)
LT (5) LT3409274T (pt)
LU (1) LUC00183I2 (pt)
MA (1) MA32981B1 (pt)
ME (2) ME03594B (pt)
MX (3) MX2011006623A (pt)
NO (1) NO2020038I1 (pt)
NZ (1) NZ593065A (pt)
PE (1) PE20120337A1 (pt)
PL (4) PL4098256T3 (pt)
PT (4) PT3453387T (pt)
RS (3) RS59857B1 (pt)
SG (1) SG171404A1 (pt)
SI (4) SI4098256T1 (pt)
SM (2) SMT202000441T1 (pt)
TN (1) TN2011000272A1 (pt)
TW (1) TW201028143A (pt)
UY (1) UY32352A (pt)
WO (1) WO2010075239A1 (pt)
ZA (2) ZA201103863B (pt)

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KR101718639B1 (ko) 2008-03-17 2017-03-21 액테리온 파마슈티칼 리미티드 선별적 ｓ1ｐ₁ 수용체 작동약에 대한 투약 섭생
RS59857B1 (sr) 2008-12-22 2020-02-28 Novartis Ag Režim doziranja agonista s1p receptora
RU2012117563A (ru) 2009-09-29 2013-11-10 Новартис Аг Режим дозирования модулятора рецептора s1p
US20110124605A1 (en) * 2009-11-20 2011-05-26 Shreeram Aradhye Use of an S1P Receptor Agonist
CA2786994C (en) 2010-01-27 2018-01-16 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
CN106309416A (zh) * 2010-05-06 2017-01-11 诺华股份有限公司 二芳基硫醚衍生物的给药方案
EP2455080A1 (en) * 2010-11-23 2012-05-23 Almirall, S.A. S1P1 receptor agonists for use in the treatment of multiple sclerosis
FR2968556B1 (fr) 2010-12-13 2013-12-27 Centre Nat Rech Scient Inhibiteurs des infections a vih et leurs utilisations
SG191286A1 (en) 2011-01-07 2013-07-31 Novartis Ag Immunosuppressant formulations
ES2716865T3 (es) 2011-02-18 2019-06-17 Scripps Research Inst Diferenciación dirigida de células precursoras de oligodendrocitos a un destino celular mielinizante
JO3177B1 (ar) 2011-04-01 2018-03-08 Novartis Ag تركيبات تتالف من 2-أمينو-2- [ 2- ( 4- أكتيل فينيل ) إثيل ] بروبان - 3, 1- ديول
US9592268B2 (en) 2011-05-23 2017-03-14 Cornell University Endothelium protective materials and methods of use
TW201320994A (zh) * 2011-10-11 2013-06-01 Novartis Ag 投藥療程
US9340518B2 (en) 2012-08-17 2016-05-17 Actelion Pharmaceuticals Ltd. Process for the preparation of (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropdxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one and intermediate used in said process
US20160129084A1 (en) * 2013-03-06 2016-05-12 Acorda Therapeutics, Inc. Therapeutic Dosing of a Neuregulin or a Fragment Thereof for Treatment or Prophylaxis of Heart Failure
US10675254B2 (en) 2013-10-11 2020-06-09 Teikoku Seiyaku Co., Ltd. Sphingosine-1-phosphate receptor agonist iontophoretic devices and methods of using the same
CN105611917A (zh) 2013-10-11 2016-05-25 帝国制药美国公司 局部鞘氨醇-1-磷酸酯受体激动剂制剂及其使用方法
TW201622721A (zh) * 2014-04-10 2016-07-01 諾華公司 Ｓ１ｐ調節劑之立即釋放劑量療法
MA41139A (fr) 2014-12-11 2017-10-17 Actelion Pharmaceuticals Ltd Combinaison pharmaceutique comportant un agoniste sélectif du récepteur sip1
PL3256125T3 (pl) 2014-12-11 2022-05-09 Actelion Pharmaceuticals Ltd Schemat dawkowania ponesimodu, selektywnego agonisty receptora s1p1
MX386419B (es) * 2015-01-06 2025-03-18 Arena Pharm Inc Metodos de condiciones de tratamiento relacionadas con el receptor s1p1.
WO2016135644A1 (en) 2015-02-26 2016-09-01 Novartis Ag Treatment of autoimmune disease in a patient receiving additionally a beta-blocker
MA42807A (fr) 2015-06-22 2018-07-25 Arena Pharm Inc Sel l-arginine cristallin d'acide (r)-2-(7-(4-cyclopentyl-3-(trifluorométhyl)benzyloxy)-1,2,3,4-tétrahydrocyclo-penta[b]indol-3-yl)acétique (composé 1) pour une utilisation dans des troubles associés au récepteur de s1p1
KR20190116416A (ko) 2017-02-16 2019-10-14 아레나 파마슈티칼스, 인크. 원발 담즙성 담관염을 치료하기 위한 화합물 및 방법
MX2019009843A (es) 2017-02-16 2020-01-30 Arena Pharm Inc Compuestos y metodos para el tratamiento de la enfermedad inflamatoria intestinal con manifestaciones extraintestinales.
KR102859841B1 (ko) 2018-06-06 2025-09-12 아레나 파마슈티칼스, 인크. S1p1 수용체와 관련된 병태의 치료 방법
CA3156298A1 (en) 2019-10-31 2021-05-06 Laetitia POUZOL Combination of a cxcr7 antagonist with an s1p1 receptor modulator
US11135197B2 (en) 2020-02-07 2021-10-05 Argentum Pharmaceuticals Llc Dosage regimen of an S1P receptor modulator
WO2021158848A1 (en) * 2020-02-07 2021-08-12 Argentum Pharmaceuticals Llc Dosage regimen of an s1p receptor agonist
JP2023515612A (ja) * 2020-02-28 2023-04-13 アカール・ファーマ・プロプライエタリー・リミテッド Ｓ１ｐ受容体調節物質
CN113332435B (zh) * 2021-06-18 2022-10-18 广州中医药大学(广州中医药研究院) 鞘氨醇-1-磷酸4受体激动剂及其与真武汤联合在制备治疗慢性肾小球肾炎药物中的应用

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JP2004507552A (ja) 2000-08-31 2004-03-11 メルク　エンド　カムパニー　インコーポレーテッド 免疫調節剤としてのリン酸誘導体
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RS59857B1 (sr) 2008-12-22 2020-02-28 Novartis Ag Režim doziranja agonista s1p receptora
JP5657565B2 (ja) 2008-12-22 2015-01-21 ノバルティス アーゲー Ｓ１ｐ受容体アゴニストの投与レジメン

Also Published As

Publication number Publication date
HRP20192175T1 (hr) 2020-03-20
JP2022103194A (ja) 2022-07-07
JP2016135752A (ja) 2016-07-28
JP2014144970A (ja) 2014-08-14
DK4098256T5 (da) 2025-07-21
WO2010075239A1 (en) 2010-07-01
EP2379067B1 (en) 2015-09-02
HUE026869T2 (en) 2016-08-29
PL3409274T3 (pl) 2020-06-01
US20160263061A1 (en) 2016-09-15
PT2379067E (pt) 2015-12-23
LT4098256T (lt) 2025-06-10
ES2760607T3 (es) 2020-05-14
TN2011000272A1 (en) 2012-12-17
ECSP11011222A (es) 2011-08-31
US20200330407A1 (en) 2020-10-22
EP4098256A1 (en) 2022-12-07
PE20120337A1 (es) 2012-04-24
EP2907511A1 (en) 2015-08-19
EP3409274B1 (en) 2019-11-20
LT3409274T (lt) 2020-02-10
US20220142949A1 (en) 2022-05-12
HN2011001759A (es) 2013-11-26
US20140148415A1 (en) 2014-05-29
EP4098256B1 (en) 2025-02-26
NO2020038I1 (no) 2020-11-18
US20190091180A1 (en) 2019-03-28
DK3409274T3 (da) 2019-12-16
CY1123255T1 (el) 2021-10-29
EA201100978A1 (ru) 2012-01-30
SG171404A1 (en) 2011-07-28
AU2009330176B2 (en) 2014-03-06
ES2552823T3 (es) 2015-12-02
ME03594B (me) 2020-07-20
MX2011006623A (es) 2011-07-12
RS66784B9 (sr) 2025-08-29
CY2020036I1 (el) 2021-03-12
CU20110136A7 (es) 2012-01-31
HRP20151190T1 (hr) 2016-01-01
HUS2000046I1 (hu) 2020-12-28
JP2017141238A (ja) 2017-08-17
RS59857B1 (sr) 2020-02-28
HRP20250568T1 (hr) 2025-07-04
CY1116990T1 (el) 2017-04-05
EP3453387B1 (en) 2020-06-03
KR20110096175A (ko) 2011-08-29
EP3120844A1 (en) 2017-01-25
TW201028143A (en) 2010-08-01
SI2379067T1 (sl) 2016-01-29
PT3409274T (pt) 2019-12-17
CO6390117A2 (es) 2012-02-29
ZA201205942B (en) 2013-03-27
US20100160259A1 (en) 2010-06-24
CR20110274A (es) 2011-07-19
SI3409274T1 (sl) 2020-03-31
EP3677260A1 (en) 2020-07-08
FR20C1060I1 (fr) 2020-12-25
ES2810823T3 (es) 2021-03-09
MA32981B1 (fr) 2012-01-02
PT3453387T (pt) 2020-08-11
HUE071189T2 (hu) 2025-08-28
AU2009330176A1 (en) 2011-07-07
NZ593065A (en) 2012-11-30
CY1122812T1 (el) 2021-05-05
US20160081949A1 (en) 2016-03-24
FR25C1012I1 (fr) 2025-06-13
CL2013001558A1 (es) 2013-10-25
PT4098256T (pt) 2025-04-10
IL278914A (en) 2021-01-31
HUE048717T4 (hu) 2022-02-28
MX2021010759A (es) 2022-07-19
RS66784B1 (sr) 2025-06-30
US20250262171A1 (en) 2025-08-21
LTPA2025520I1 (pt) 2025-06-25
LUC00183I2 (pt) 2024-07-01
SMT202000441T1 (it) 2020-09-10
JP2024129030A (ja) 2024-09-26
HUE052048T2 (hu) 2021-04-28
IL213170A0 (en) 2011-07-31
KR101347919B1 (ko) 2014-01-07
FIC20253002I1 (fi) 2025-05-23
ES3017254T3 (en) 2025-05-12
EP3409274A1 (en) 2018-12-05
PL2379067T3 (pl) 2016-02-29
CA2747802A1 (en) 2010-07-01
US20170189353A1 (en) 2017-07-06
HUE048717T2 (hu) 2020-08-28
JP2012513401A (ja) 2012-06-14
ZA201103863B (en) 2012-10-31
PL4098256T3 (pl) 2025-06-09
UY32352A (es) 2010-07-30
DK2379067T3 (en) 2015-12-07
SI4098256T1 (sl) 2025-06-30
IL274756A (en) 2020-07-30
CN102264359A (zh) 2011-11-30
EP4098256B9 (en) 2025-06-18
US20110257133A1 (en) 2011-10-20
US20140066657A1 (en) 2014-03-06
RS60666B1 (sr) 2020-09-30
EP3453387A1 (en) 2019-03-13
JP7329965B2 (ja) 2023-08-21
CA2747802C (en) 2021-02-09
LT3453387T (lt) 2020-08-25
AU2009330176C9 (en) 2017-01-05
ME03802B (me) 2021-04-20
SMT202000054T1 (it) 2020-03-13
MX385959B (es) 2025-03-18
US20180289638A1 (en) 2018-10-11
LTPA2020005I1 (lt) 2020-12-10
CY2020036I2 (el) 2021-06-25
DK3453387T3 (da) 2020-08-10
DK4098256T3 (da) 2025-04-22
AU2009330176C1 (en) 2016-12-08
PL3453387T3 (pl) 2020-11-02
HRP20201167T1 (hr) 2020-12-11
SI3453387T1 (sl) 2020-10-30
HUS2500026I1 (hu) 2025-07-28
CL2011001529A1 (es) 2012-02-24
FI4098256T3 (fi) 2025-03-31
JP2019167360A (ja) 2019-10-03
EP2379067A1 (en) 2011-10-26
AR074826A1 (es) 2011-02-16

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