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BRPI0923015A2 - enxertos ósseos com atividade de protease reduzida e métodos de seleção e uso - Google Patents

enxertos ósseos com atividade de protease reduzida e métodos de seleção e uso

Info

Publication number
BRPI0923015A2
BRPI0923015A2 BRPI0923015A BRPI0923015A BRPI0923015A2 BR PI0923015 A2 BRPI0923015 A2 BR PI0923015A2 BR PI0923015 A BRPI0923015 A BR PI0923015A BR PI0923015 A BRPI0923015 A BR PI0923015A BR PI0923015 A2 BRPI0923015 A2 BR PI0923015A2
Authority
BR
Brazil
Prior art keywords
selection
methods
protease activity
bone grafts
reduced protease
Prior art date
Application number
BRPI0923015A
Other languages
English (en)
Inventor
Charles E Hart
Conan S Young
Leo B Snel
Vladimir Kery
Original Assignee
Biomimetic Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomimetic Therapeutics Inc filed Critical Biomimetic Therapeutics Inc
Publication of BRPI0923015A2 publication Critical patent/BRPI0923015A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
BRPI0923015A 2008-12-19 2009-12-18 enxertos ósseos com atividade de protease reduzida e métodos de seleção e uso BRPI0923015A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13944808P 2008-12-19 2008-12-19
US14999809P 2009-02-04 2009-02-04
US15431109P 2009-02-20 2009-02-20
PCT/US2009/068873 WO2010071857A1 (en) 2008-12-19 2009-12-18 Bone grafts with reduced protease activity and methods of selection and use

Publications (1)

Publication Number Publication Date
BRPI0923015A2 true BRPI0923015A2 (pt) 2015-12-15

Family

ID=42269133

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0923015A BRPI0923015A2 (pt) 2008-12-19 2009-12-18 enxertos ósseos com atividade de protease reduzida e métodos de seleção e uso

Country Status (11)

Country Link
US (1) US20100196347A1 (pt)
EP (1) EP2376106A4 (pt)
JP (1) JP2012512728A (pt)
KR (1) KR20110100269A (pt)
CN (1) CN102316890A (pt)
AU (1) AU2009327377A1 (pt)
BR (1) BRPI0923015A2 (pt)
CA (1) CA2747508A1 (pt)
IL (1) IL213608A0 (pt)
MX (1) MX2011006586A (pt)
WO (1) WO2010071857A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
EP1951327A2 (en) 2005-11-17 2008-08-06 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
WO2007092622A2 (en) 2006-02-09 2007-08-16 Biomimetic Therapeutics, Inc. Compositions and methods for treating bone
WO2008005427A2 (en) 2006-06-30 2008-01-10 Biomimetic Therapeutics, Inc. Pdgf-biomatrix compositions and methods for treating rotator cuff injuries
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
CA2668189C (en) 2006-11-03 2016-01-26 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures comprising a solution of platelet derived growth factor (pdgf) incorporated in a biocompatible matrix
EP2125000A2 (en) * 2007-02-20 2009-12-02 Biomimetic Therapeutics, Inc. Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using pdgf and a bone matrix
CA2715254A1 (en) 2008-02-07 2009-08-13 Biomimetic Therapeutics, Inc. Compositions and methods for distraction osteogenesis
CN102515576B (zh) * 2011-12-05 2016-03-30 韩大庆 磷酸镁水泥用氧化镁及其制备方法和磷酸镁水泥
EP3206670A4 (en) 2014-10-14 2018-06-20 Samuel Lynch Compositions for treating wounds
PL3370698T3 (pl) 2015-11-03 2022-04-25 Zoetis Services Llc Kompozyty polimerowe zol-żel i ich zastosowania
WO2017151919A1 (en) 2016-03-02 2017-09-08 The Regents Of The University Of Michigan Engineered tendon graft for rotator cuff repair
CN105748177B (zh) * 2016-04-20 2018-01-02 华南理工大学 一种个性化具有仿生微孔的脊椎植入假体及其制造方法
CN111220608B (zh) * 2020-02-05 2022-02-15 江苏大学 基于硫化改性的CoOx的碱性磷酸酶活性比色检测法
CN112986499A (zh) * 2021-02-26 2021-06-18 山西奥瑞生物材料有限公司 一种同种骨植入材料残余水量均匀度测定方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5112354A (en) * 1989-11-16 1992-05-12 Northwestern University Bone allograft material and method
US5011910A (en) * 1989-12-28 1991-04-30 Washington University Reagent and method for determining activity of retroviral protease
US5460962A (en) * 1994-01-04 1995-10-24 Organogenesis Inc. Peracetic acid sterilization of collagen or collagenous tissue
US6739112B1 (en) * 2000-08-21 2004-05-25 Nu Vasive, Inc. Bone allograft packaging system
WO2003106703A2 (en) * 2002-06-14 2003-12-24 Pierce Biotechnology, Inc. Homogenous assay for enzymatic activity
EP1708651A4 (en) * 2004-01-27 2011-11-02 Osteotech Inc STABILIZED BONE PROOF
CA2581328A1 (en) * 2004-09-21 2006-03-30 Massachusetts Institute Of Technology Gradient scaffolding and methods of producing the same
US7473678B2 (en) * 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
EP1909810B2 (en) * 2005-06-07 2017-08-23 The Regents of the University of Colorado Inhibitors of serine protease activity and their use in methods and compositions for treatment of graft rejection and promotion of graft survival
EP1951327A2 (en) * 2005-11-17 2008-08-06 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
WO2007092622A2 (en) * 2006-02-09 2007-08-16 Biomimetic Therapeutics, Inc. Compositions and methods for treating bone
EP3207948B1 (en) * 2007-06-15 2020-02-26 Warsaw Orthopedic, Inc. Bone matrix compositions and methods

Also Published As

Publication number Publication date
MX2011006586A (es) 2011-06-30
AU2009327377A1 (en) 2011-07-14
US20100196347A1 (en) 2010-08-05
CN102316890A (zh) 2012-01-11
KR20110100269A (ko) 2011-09-09
JP2012512728A (ja) 2012-06-07
WO2010071857A1 (en) 2010-06-24
EP2376106A4 (en) 2013-01-09
CA2747508A1 (en) 2010-06-24
IL213608A0 (en) 2011-07-31
EP2376106A1 (en) 2011-10-19

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]