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BRPI0922708A2 - peptídeos mini-hepcidina e métodos de uso do mesmo - Google Patents

peptídeos mini-hepcidina e métodos de uso do mesmo

Info

Publication number
BRPI0922708A2
BRPI0922708A2 BRPI0922708A BRPI0922708A BRPI0922708A2 BR PI0922708 A2 BRPI0922708 A2 BR PI0922708A2 BR PI0922708 A BRPI0922708 A BR PI0922708A BR PI0922708 A BRPI0922708 A BR PI0922708A BR PI0922708 A2 BRPI0922708 A2 BR PI0922708A2
Authority
BR
Brazil
Prior art keywords
minihepidine
peptides
methods
minihepidine peptides
Prior art date
Application number
BRPI0922708A
Other languages
English (en)
Inventor
Nemeth Elizabeta
Preza Gloria
Ruchala Piotr
Ganz Tomas
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of BRPI0922708A2 publication Critical patent/BRPI0922708A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BRPI0922708A 2008-12-05 2009-12-04 peptídeos mini-hepcidina e métodos de uso do mesmo BRPI0922708A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12027708P 2008-12-05 2008-12-05
PCT/US2009/066711 WO2010065815A2 (en) 2008-12-05 2009-12-04 Mini-hepcidin peptides and methods of using thereof

Publications (1)

Publication Number Publication Date
BRPI0922708A2 true BRPI0922708A2 (pt) 2018-11-06

Family

ID=42233878

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922708A BRPI0922708A2 (pt) 2008-12-05 2009-12-04 peptídeos mini-hepcidina e métodos de uso do mesmo

Country Status (6)

Country Link
US (2) US8435941B2 (pt)
EP (2) EP2373679B1 (pt)
CN (1) CN102245626A (pt)
AU (1) AU2009322260B2 (pt)
BR (1) BRPI0922708A2 (pt)
WO (1) WO2010065815A2 (pt)

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CA2448382C (en) 2001-05-25 2013-02-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Use of hepcidin as a regulator of iron homeostasis
US9328140B2 (en) * 2008-12-05 2016-05-03 The Regents Of The University Of California Modified mini-hepcidin peptides and methods of using thereof
WO2010065815A2 (en) * 2008-12-05 2010-06-10 The Regents Of The University Of California Mini-hepcidin peptides and methods of using thereof
CN101955525B (zh) * 2010-07-13 2012-11-07 中国农业科学院兰州畜牧与兽药研究所 一种人工抗菌肽及其基因与制备方法
EP2668497B1 (en) * 2011-01-26 2020-03-25 University of Pittsburgh - Of the Commonwealth System of Higher Education Urine biomarkers for prediction of recovery after acute kidney injury : proteomics
JP6501362B2 (ja) * 2012-11-01 2019-04-17 ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア エリスロフェロンおよびｅｒｆｅポリペプチドならびに鉄代謝を調節する方法
GB201302837D0 (en) * 2013-02-19 2013-04-03 Univ Singapore Therapeutic Agents
EP2968503B1 (en) * 2013-03-15 2018-08-15 Intrinsic LifeSciences LLC Anti-hepcidin antibodies and uses thereof
AU2014232954B2 (en) * 2013-03-15 2018-08-09 Protagonist Therapeutics, Inc. Hepcidin analogues and uses therof
EP2976085A1 (en) 2013-03-21 2016-01-27 INSERM - Institut National de la Santé et de la Recherche Médicale Method and pharmaceutical composition for use in the treatment of chronic liver diseases associated with a low hepcidin expression
EP3129040A4 (en) * 2014-04-07 2018-03-21 La Jolla Pharmaceutical Company Hepdicin mimetic peptides and uses thereof
KR102787208B1 (ko) 2014-05-16 2025-03-27 프로타고니스트 테라퓨틱스, 인코포레이티드 α4β7 인테그린 티오에테르 펩티드 길항제
WO2015200916A2 (en) * 2014-06-27 2015-12-30 Protagonist Therapeutics, Inc. Hepcidin and mini-hepcidin analogues and uses therof
BR112017001010A2 (pt) 2014-07-17 2017-11-14 Protagonist Therapeutics Inc inibidores peptídicos orais do receptor de interleucina-23 e seu uso para tratar doenças inflamatórias intestinais
WO2016049036A1 (en) 2014-09-22 2016-03-31 Intrinsic Lifesciences Llc Humanized anti-hepcidin antibodies and uses thereof
BR112017006826A2 (pt) 2014-10-01 2017-12-12 Protagonist Therapeutics Inc novos monômeros e dímeros peptídicos a4ss7 antagonistas
WO2016054445A1 (en) 2014-10-01 2016-04-07 Protagonist Therapeutics, Inc. Novel cyclic monomer and dimer peptides having integrin antagonist activity
EP3240799B1 (en) * 2014-12-29 2021-03-31 The Regents of the University of California S-alkylated hepcidin peptides and methods of making and using thereof
US10787490B2 (en) 2015-07-15 2020-09-29 Protaganist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
US20190002503A1 (en) 2015-12-30 2019-01-03 Protagonist Therapeutics, Inc. Analogues of hepcidin mimetics with improved in vivo half lives
SG11201805755SA (en) * 2016-01-08 2018-08-30 La Jolla Pharmaceutial Company Methods of administering hepcidin
CA3017926C (en) 2016-03-23 2023-10-10 Protagonist Therapeutics, Inc. Methods for synthesizing .alpha.4.beta.7 peptide antagonists
EP3497127A1 (en) * 2016-08-05 2019-06-19 Silarus Therapeutics, Inc. Erfe specific antibodies compositions and methods of use
WO2018048944A1 (en) * 2016-09-06 2018-03-15 La Jolla Pharmceutical Company Methods of treating iron overload
WO2018107241A1 (en) * 2016-12-16 2018-06-21 The University Of Sydney Treatment of iron disorders
WO2018128828A1 (en) 2016-12-23 2018-07-12 Bayer Healthcare Llc Novel hepcidin mimetics and uses thereof
WO2018175633A1 (en) * 2017-03-22 2018-09-27 La Jolla Pharmaceutical Company Methods of inducing anti-malarial immune responses and compositions related thereto
WO2019051494A1 (en) 2017-09-11 2019-03-14 Protagonist Therapeutics, Inc. OPIOID AGONIST PEPTIDES AND USES THEREOF
EP3749345A4 (en) 2018-02-08 2022-04-06 Protagonist Therapeutics, Inc. CONJUGATED HEPCIDIN MIMETICS
US11286243B2 (en) 2018-12-13 2022-03-29 Global Blood Therapeutics, Inc. Ferroportin inhibitors and methods of use
AU2020311395A1 (en) 2019-07-10 2022-02-03 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
KR20220141808A (ko) 2020-01-15 2022-10-20 얀센 바이오테크 인코포레이티드 인터루킨-23 수용체의 펩티드 억제제 및 염증성 질환을 치료하기 위한 이의 용도
TW202515892A (zh) 2020-01-15 2025-04-16 美商健生生物科技公司 介白素-23受體之肽抑制劑及其治療發炎性疾病之用途
CA3181583A1 (en) 2020-04-28 2021-11-04 Global Blood Therapeutics, Inc. Methods of use for pyrimidines as ferroportin inhibitors
MX2022013518A (es) 2020-04-28 2023-02-01 Global Blood Therapeutics Inc Pirimidinas cicloalquiladas como inhibidores de la ferroportina.
CA3181577A1 (en) 2020-04-28 2021-11-04 Global Blood Therapeutics, Inc. Thieno pyrimidines as ferroportin inhibitors
CN115997130A (zh) * 2020-07-02 2023-04-21 坦佩雷大学注册基金会 基于肾素的铁调素分析
CA3202226A1 (en) 2020-11-20 2022-05-27 Janssen Pharmaceutica Nv Compositions of peptide inhibitors of interleukin-23 receptor
JPWO2022154121A1 (pt) * 2021-01-18 2022-07-21
JP2024513391A (ja) * 2021-04-01 2024-03-25 プロタゴニスト セラピューティクス， インコーポレイテッド コンジュゲートされたヘプシジン模倣物
WO2023288019A2 (en) 2021-07-14 2023-01-19 Janssen Biotech, Inc. Lipidated peptide inhibitors of interleukin-23 receptor
CN115703826B (zh) * 2021-08-03 2025-05-06 浙江大学 铁调素改造体及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2137829A1 (en) * 1992-06-12 1993-12-23 Pang, Peter K. T. Active component of parathyroid hypertensive factor
JP2891023B2 (ja) * 1993-03-09 1999-05-17 味の素株式会社 ランチオニン含有物の製造方法
DE10228103A1 (de) 2002-06-24 2004-01-15 Bayer Cropscience Ag Fungizide Wirkstoffkombinationen
RU2359268C2 (ru) * 2002-11-19 2009-06-20 ДиАрДжи ИНТЕРНЭШНЛ, ИНК. Способ диагностики заболеваний путем скрининга тканей, крови или жидкостей организма животных или человека на предмет обнаружения нефизиологических уровней гепсидина и его терапевтическое применение
US20070166711A1 (en) 2003-04-15 2007-07-19 Samuels Mark E Juvenile hemochromatosis gene (hfe2a), expression products and uses thereof
CA2549477A1 (en) 2005-06-29 2006-12-29 The Regents Of The University Of California Competitive regulation of hepcidin mrna by soluble and cell-associated hemojuvelin
JP2010517529A (ja) 2007-02-02 2010-05-27 アムジエン・インコーポレーテツド ヘプシジン及びヘプシジン抗体
WO2010065815A2 (en) * 2008-12-05 2010-06-10 The Regents Of The University Of California Mini-hepcidin peptides and methods of using thereof
US9328140B2 (en) * 2008-12-05 2016-05-03 The Regents Of The University Of California Modified mini-hepcidin peptides and methods of using thereof

Also Published As

Publication number Publication date
AU2009322260B2 (en) 2013-09-12
US8435941B2 (en) 2013-05-07
EP2373679A2 (en) 2011-10-12
CN102245626A (zh) 2011-11-16
AU2009322260A1 (en) 2011-07-07
US20120040894A1 (en) 2012-02-16
US20130203662A1 (en) 2013-08-08
EP2373679B1 (en) 2017-03-08
WO2010065815A3 (en) 2010-10-21
EP2373679A4 (en) 2012-05-30
WO2010065815A2 (en) 2010-06-10
EP3208279A1 (en) 2017-08-23
EP3208279B1 (en) 2021-04-21

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A, 7A, 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2497 DE 13-11-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.