BRPI0903829A2 - devices and methods for carrying out radiofrequency microsclerosis optionally associated with chemosclerosis in the treatment of telangiectasias and small varicose veins - Google Patents

Abstract

DEVICES AND METHODS FOR THE PERFORMANCE OF MICROSCLEROSIS BY RADIOFREQUENCY ASSOCIATED, OPTIONALLY, TO CHEMIOSKEROSIS IN THE TREATMENT OF TELANGIECTASIAS AND SMALL CALIBER VARIATIONS This invention relates to devices and methods, for use in the medical field, which aim at eliminating diseases and methods aimed at eliminating diseases small caliber, using radiofrequency fulguration, performed, optionally and simultaneously, with chemosclerosis, using a special disposable and modified needle (15) and syringe (31), and an electric radio frequency generator, with some accessories . The aforementioned needle (15) has its metallic cannula (27), almost completely externally covered by a micro layer of insulating material (1), with only a small surface of its tip without insulation (6). The invention provides means for connecting the non-insulated tip of the needle cannula (6) and a metallic contact pin (19), located on the tip of one of the syringe flanges (25). This contact is connected to the positive pole of the radio frequency generator (34), while the negative pole of this generator (35) is connected to the patient's skin. After puncture of the vessel, a small amount of the liquid contained in the syringe (31) is injected, confirming the correct location of the needle tip, then firing the radiofrequency electrical pulses, glowing and eliminating the dilated vessel, with great selectivity. As the syringe (31) and needle (15) maintain their normal conformations and functionalities, chemosclerosis can also be performed simultaneously, if the medical professional so desires.

Description

"DEVICES AND METHODS FOR THE PERFORMANCE OF RADIO-FREQUENCY DAMICOSCLEROSIS, OPTIONALLY ASSOCIATED WITH CHEMOSCLEROSIS IN TREATMENT OF SMALL SIZE TELANGIECTASIES"

Telangiectasias, also known as micro varicose veins, are capillary, arterial, or venous dilations smaller than 2 mm in size, which sometimes cluster together to form vast tangles. Small-caliber varicose veins, on the other hand, are 1 to 3 mm veins, whose walls are dilated by primary fragility, of genetic etiology, and / or by overload on intravasal pressure. They may be present in any part of the body, most commonly in the lower limbs, where it produces increased venous pressure, causing painful and aesthetic discomfort.

Several medical treatments have been proposed to eliminate telangiectasia and small varicose veins:

- chemosclerosis, the most commonly used technique, most often done without anesthesia, with a fine-caliber needle, which consists of injecting ditosesclerosing irritating and / or hyperosmolar material into the light of these vessels with the intention of destroying its internal layer. causing fibrosis and its disappearance. In spite of the effectiveness of the method, sometimes several injections of sclerosing into the same group of vessels, performed at sessions at weekly intervals, are necessary to obtain a satisfactory result, ie its elimination.

- Laser sclerosis, which makes use of the properties of a light-colored beam of definite length in order to "burn" the vessel, but has several restrictions, including being effective in certain types of vessel, often causing staining. on the skin and can only be prescribed for light-skinned patients.

- application of high intensity pulsed light, which uses high intensity light, applied over very short periods of time, to the vessels to be treated, with the intention of "burning" them and which not only often produces serious dermal burns, but also little. used today.

- surgery, which is nothing more than the extraction of varicose veins with a fine hooked needle through small staggered incisions and is commonly indicated for larger venous dilations.

- electrosclerosis

Electrosclerosis is a varicose vein elimination method that uses a solid, non-light needle, whereby high-frequency pulses are applied to telangiectasias or small-caliber varicose veins, making use of an electric radiofrequency generator (RF generator), which is nothing but an electric scalpel in order to "burn" these vasostrabed. These "burned" vessels are replaced by fibrotic scar tissue and disappear.

These high-frequency electric generators operate in a frequency range from 300 Khz to 4 Mhz, and produce heat heating, dehydrating and destroying it.

Despite its effectiveness, electrosclerosis has so far been limited by not isolating the other tissues well, causing the electrical tip of the parasite to "burn" also neighboring attachments, including the skin, which is only bearable under local anesthesia. As it also affects the skin, this method generates undesirable dermal crusts, which can develop into definitive hypochromic stains, sequelae to burns. The difficulty in performing this therapeutic method in telangiectasia arises from the very thin caliber of these vessels and, mainly, from their extremely superficial location, which is often less than 0.5 mm from the skin, causing difficulty in selecting only telangiectasia, at the time of "burning" it, leaving the skin and surrounding tissues intact.

The isolated needle models presented so far leave a long distal extension without isolation, resulting, in the case of detangangiectasias, in the joint burning of the skin and other tissues, besides generating intense painful sensation. Another alternative method suggested the use of these same needles, puncturing at a point on the skin, far from the vessel, and a variable subdermal pathway, until the entire insulated part of the needle had penetrated, and its tip reached the vessel, applying it. the discharge is made without the skin being struck; This method was unsatisfactory, as numerous "bites" are performed during a session of varicose vein sclerosis, usually more than 30, making the needle pass through large segments of tissue makes the procedure very painful and impractical without anesthesia. Furthermore, with respect to the same method, the large uncoated distal extension of these needles may not "burn" the skin, but it does not cease to destroy adjacent subdermal patches, which is undesirable, and which also increases patient discomfort. In addition, no device was developed that allowed the simultaneous performance of Echosclerosis Electrosclerosis.

The proposed invention aims at medical devices and methods for performing radiofrequency microsclerosis, which does not cause significant puncture and "burning" of telangiectasia or small caliber, doing so selectively, leaving the other unaffected tissues and which may be performed concurrently with achiosclerosis. It will greatly increase the effectiveness of the sclerotherapy procedures in use today for the following reasons:

- As a hollow cannula needle with lumen, achiosclerosis is used, the most widely used treatment today can be used simultaneously with microsclerosis, without modifying its technique, adding its sclerosing actions and increasing its effectiveness, reducing the number of sessions and obtaining shorter-term results.

- As the proposed needles are of very fine caliber with very sharp, the pain and discomfort caused by puncture datelangiectasia or small varicose vein will be extremely bearable, not differing from those caused by the "bites" of the current chemo sclerosis.

- Before the cauterizing electric discharge is performed, the injection of sclerosing substances or small amounts of liquid will allow the doctor to make sure that the needle is correctly positioned inside the vessel. This is possible because sclerosing liquid is usually colorless, and when this substance is injected into the vessel, it disappears momentarily, so that blood, reddish in color, is replaced by colorless liquid, making sure that the doctor performing the procedure is sure to pointing needle is correctly located in the vessel light.

- in the case of telangiectasias of the face, where there are contraindications to chemosclerosis, or in cases where the medical professional prefers to perform radiofrequency microsclerosis alone, there is nothing to prevent the use of sclerosing fluid and to inject it prior to microcautery only a neutral substance such as distilled water mixed with a certain amount of anesthetic to ensure the correct location of the needle tip.

- The very fine needle, together with its small area partecoder, which will only be in contact with the inner surface of the small vessel, will allow a much lower power output, reducing pain and discomfort.

The invention and proposed methods hereinafter do not prevent other adjuvants from being combined in order to further increase efficacy and reduce pain, such as cryosclerosis, cold air-anesthesia and the addition of small amounts of anesthetic to the body. liquid to be injected.

In order to achieve the above objectives, it is necessary to use a syringe and needle, with the same conformation of the current, with some modifications, that is: - the needle should have only a small area of its tip, not isolated, to be burned. , selectively, only the inner datelangiectasia or the small caliber varicose vein.

- Insulation of the needle should be made of a material that can be applied to a very thin, preferably lesser, microclayer.

at 100 microns, so as not to cause sharp unevenness in the needle-introducing surface, which would increase pain during the puncture process of the skin.

- There must be an efficient mechanism for electrical conduction, from uninsulated needle points to the syringe flange, which is the ideal place to connect the wire to the positive pole of the radio frequency generator where wiring does not impair the handling of the syringe. .

- Since the same needle should be used for multiple punctures, mechanisms should be in place to prevent unwanted tissue adhesion on the uninsulated needle point after the coagulation pulses would be applied, which would deteriorate the bevel wire making it difficult to puncture another vasoa to be treated.

- the syringe and needle must have a similar arrangement and functionality as those available on the market for the injection of sclerosing or neutral fluid, allowing simultaneous chemosclerosis and / or to be sure of the correct location of the needle tip.

- the syringe and needle should be disposable and inexpensive.

Because they are very small vessels, the RF generator must also have specific characteristics such as low power, up to 20 watts, and small power regulation, preferably at 0.1 watt intervals, or smaller.

In order to avoid tissue adhesion to the uninsulated needle tip, which is common when using an electrocautery, I propose some useful methods that are effective in daily practice. First, it is observed that when the cooling of the tip of an electrocautery is used, this adhesion does not occur, or occurs in a reduced degree. The joint use of dacryosclerosis, which consists in cooling the syringe containing the liquid to be injected, at temperatures from 0 to -40 degrees Celsius, is particularly useful because, besides avoiding undesirable adhesion, the method benefits the cryosclerosis. These benefits, cited in the literature and already proven in medical practice, are the increased efficacy of chemosclerosis, due to the severe cooling of the injected liquid, which helps to cause greater destruction of the internal wall of the vessel, less pain because the cold has anesthetic properties and decreased microhematomas, since cold also has vasoconstrictor action.

Another tactic used to combat this stickiness is to apply the electric pulse before the liquid injection is completely completed. The final flow of the injected liquid is to prevent tissue adhesion.

The invention will now be described with reference to typical embodiments thereof and also with reference to the accompanying drawings in which:

Figure 1 illustrates a side view of the proposed needle metal cannula according to the invention.

Figure 2 illustrates, in longitudinal section, version number 1 of one of the proposed needle cannulas according to the invention.

Figure 3 illustrates, in longitudinal section, version number 2 of one of the proposed needle cannulas according to the invention.

Figure 4 illustrates, in longitudinal section, version number 3 of one of the proposed needle cannulas according to the invention.

Figure 5 illustrates, in cross-section, the layers of the insulated metal cannula part common to all proposed cannula versions according to the invention.

Figure 6 illustrates a side view of the proposed complete needle according to the invention.

Figure 7 illustrates, in longitudinal section, the layers of version 1 of the proposed complete needle according to the invention.

Figure 8 illustrates, in longitudinal section, the layers of version number 2 of the proposed complete needle according to the invention.

Figure 9 illustrates a side view of the proposed syringe according to the invention.

Figure 10 illustrates in longitudinal section the layers of the proposed syringe according to the invention.

Figure 11 shows, in enlarged longitudinal section, details of the distal end of the proposed syringe and its connection with the proposed needle according to the invention.

Figure 12 illustrates an overview of all proposed devices and their connections.

Referring to figure 1, we have a side view of the metal needle cannula, and its parts can be observed: the bevel (26), which is the sharpened and sharp part of the metal cannula (27), and serves to perform tissue penetration, causing the least possible pain, and the cannula-metal itself (27), isolated externally and hollow internally, through which, in the lumen (14), the medication circulates. In this figure 2 sections have been proposed: one longitudinal, which will serve to detail the inner layers of the 3 versions of the proposed needle cannulae (Figs. 2, 3 and 4), and transverse, which will serve to detail how the insulating material surrounds the metal cannula (27) .

Regarding Figure 2, we see, in longitudinal section, the number 1 version of the layers of one of the proposed metal cannulas, which is especially useful in the treatment of thinner telangiectasias, since it had only a minimal non-isolated distal area. The distance (B) corresponds to the outer diameter of the bezel (26). The outer layer (1), not pictured here in any proportion (nor in Figs. 3, 4 and 5), due to its very thin thickness, is composed of insulating materials that can be applied in micro-layer, mentioning, for example, Teflon ® (polytetrafluoroethylene). ) which, under proper treatment, adheres very well to the metal. In order not to disrupt the penetration of the bevel (26) and / or the metal cannula (27) into the skin, the multilayer should be less than 100 microns thick, varying proportionally to the needle size. We see that the insulating layer (1) extends also to the bevel (26) of the needle, covering its upper half (Γ). The uninsulated portion of the cannula (6, 6 ') of this version extends superiorly (6') over the entire surface of the lower half of the bevel (26) (half of the distance B) and inferiorly (6) extends throughout the circumference of the metal cannula (27), from its extreme tip, to the vertical line (F), which crosses superiorly the half of the bevel (26). This isolation can be applied to existing market sized needles manufactured by various companies for use in chemosclerosis sessions, specifically the 30 G Vz, 27 G '/ 2 and 26 GVz needles, and may vary for larger gauges according to the dastelangiectasias caliber. or small varicose veins. Said needles have a diameter ranging from 0.3 mm to 0.45 mm.

Referring to figure 3, we observe the version number 2 of the layers of one of the proposed metal cannulae, differing from version number 1 (fig.2) only in that the entire surface of the bevel (26) is not isolated (6 ") and therefore The uninsulated part also extends through the distal metal cannula (6), covering its entire circumference, from its extreme tip to the vertical line (G), which crosses the upper edge of the bevel (26) (distance C).

This version is indicated for the treatment of telibiectasis of caliber, using 30 G Vz, 27 G Vz and 26 G Vz and 25 GV-z needles, with a diameter ranging from 0.3 mm to 0.5 mm.

Referring to figure 4, we observe the version number 3 of the layers of one of the proposed metal cannulae, differing from version number 2 (fig.3) only in that it presents a greater extension of the distal metal cannula (6.6 "'). (D) ranges from 0.5 to 5 mm and the distance (E) extends to a vertical line (H), which crosses the proximal limit of the distance (D) .This version is indicated for the treatment of larger decalibular telangiectasias and for small caliber varicose veins, where a larger electrical contact area is required, using gauge needles equal to or larger than the 27 G V2 needle, ie with diameters greater than 0.4 mm.

Referring to Figure 5, we see, non-proportionally, due to the micro-thickness of the insulating layer, in cross section, defined in Figure 1, the layers of the insulated part of the metal cannula (27), being the very thin outer layer formed by the material. insulator (1), internally by the metal part of the cannula (28) and its lumen (14).

Referring to figure 6, we can see a lateral view of the complete needle (15), noting the isolated (1) and the non-isolated (6) metallic cannula (27) and the plastic cannon (18), responsible for fitting the needle into the needle. syringe nozzle. The needle barrel (18) may or may not have a thin conductive metal base (9) according to the proposed version.

In this figure a longitudinal section was proposed, which serves to detail its inner layers, in figures 7 and 8. This model serves to assemble all versions of the proposed needle cannulae (figs. 2, 3 and 4).

With respect to figure 7, we have, in longitudinal section, the inner layers of the version 1 of the needle barrel, illustrated in figure 6, and it can be seen that the metal cannula (27) connects (11) with a thin electrical conductor (12). ), which in turn travels internally through the plastic bed of the needle cannon (18), ending its course in contact with metallic contacts of the needle cannon (9), which cover all its base. The distance (A) refers to the total length of the cannula (27) and may vary from 13 mm to 40 mm, depending on its size.

This model is suitable for mounting all versions of the proposed needle cannulae (Figs. 2, 3 and 4).

Referring to figure 8, we have, in longitudinal section, the inner layers of version 2 of the needle barrel (18), illustrated in figure 6. Unlike version number 1 (Fig. 7), it can be seen that here the metal cannula (27) connects (1Γ) with a conductive material (9 ') either partially or totally covering the inner part of the plastic barrel (18).

The distance (A) refers to the total length of the metal cannula (27) and may range from 13 mm to 40 mm depending on its caliber. These models are suitable for mounting all versions of the proposed needle cannulae (Figs. 2, 3 and 4).

Referring to Figure 9, a side view of the syringe can be seen from which the needle-fitting nozzle 16 and its inner nozzle 16 ', the cylindrical barrel (17), the plunger rod (55) can be seen. and the flange (25). Unlike a standard syringe, it has, at the end of one of the flanges (25), a metal connector pin (19), which serves for external electrical connection by means of a thin, malleable electrical wire to a radiofrequency electric generator, low power. This disposable syringe is made of plastic material and can have variable dimensions, with a capacity for a net volume of 1 to 10 ml, preferably 3 ml for telangiectasias and 5 ml for small caliber varicose veins.

In this figure a longitudinal section was proposed, which will serve to detail its inner layers, in figure 10.

Referring to figure 10, we see in longitudinal section the inner layers of the syringe illustrated in figure 9. In this section we can see the waterproof rubber distal plunger (24). At the base of the syringe nozzle (16) and / or partially or fully covering the dobic outer surface of the syringe (16 ') are thin metallic counts (21, 21') which connect with a thin electrical conductor (20), extending throughout the cylindrical drum (17) and one of the flanges (25), extending at the end of one of the flanges (25) as a metal pin (19), for external connection, by means of an electric wire malleable and fine caliber, low power electric radiofrequency generator. The liquids to be injected are stored inside the syringe barrel (23).

Referring to figure 11, we observe, with image enlargement, for a more detailed view, the connection (54) between the inside covered by the electrical conductor material of the needle barrel (9 ') and / or the basemetallic needle barrel (9) and the electrically conductive exterior of the syringe nozzle (21 ') and / or the metal base of the syringe nozzle (21). Syringe tip contacts (21, 21 ') continue to be a common thin electrical conductor (20) extending the full length of the cylindrical end (17).

Referring to figure 12, we have an overview of all devices used and their connections. The radio frequency electric generator, hereinafter simply referred to as the RF generator (32), operates in monopolar mode, has a power ranging from 0 to 20 Watt and works at a frequency between 300 Khz and 4 Mhz, preferably in the range of 2 Mhz. composed of an alpha numeric display (33), it has a positive polarity connection for the syringe (34), a patient ground connection (35) and a multi-pin pedal connection (36). Controls (37) adjust power from 0 to 20 Watts, with increments of 0.1 Watt or less, and common-use presets, which can be quickly selected during treatment by simply pressing the control pedal. pulse power (40).

The trigger and pulse power control pedal (38) is dual and consists of a pedal on the right, which serves to trigger the pulse (39) and the other on the left (40), for the selection of presets previously set by the physician. vary according to vessel caliber. This pedal is connected to the RF generator (32) by an electrical cable (41) and a pin metal (42).

The patient's bracelet or ankle (52) is composed of a lined velko strap (43), internally lined with electrically conductive material (45), which should be covered by electrolytic gel of good conductivity, which will make contact with the skin of the patient. wrist or ankle of the patient. It has a female pin on the side (44) and connects to the ground output (35) of the RF generator (32) by means of a malleable wire with connectors at its ends. Eventually, the patient's brace or ankle brace (52) may be replaced by a placametalic, which will make contact with his skin.

The doctor's bracelet (53) serves only as a support for the wire, preventing it from weighting the syringe, thus facilitating its handling. It is comprised of a lined velko strip (47) with a double female pin on the side (48), which connects to the wire (51) which connects to the positive pole (34) of the RF generator (32) and to the wire (49) which connects to the syringe flange pin (19). These connections on the wristband are useful as they allow the doctor to disconnect and reconnect the wires, providing greater mobility of the professional in the office.

The methodology for using the devices varies according to the location of telangiectasias or small varicose veins.

In the lower limbs, it is preferable to use FR porosclerosis associated with chemosclerosis. In this case, after placing the bracelets, the connections are made with the appropriate wires, and the patient's ankle bracelet (52) has previously the internal surface covered by a small amount of conductive electrolyte gel, sclerosing liquid aspirates, preferably the 75% glucose for the special RF microsclerosis syringe (31) using a larger, common needle and mixing a small amount of anesthetic fluid in the proportion from 1 to 10 to 3 to 10, preferably lidocaine. at 2 or 3%.

The special RF microsclerosis needle (15) is then connected to the syringe and the thread (49) connected to the syringe pin (19) and medical bracelet pin (48). The doctor then chooses the appropriate preset for the caliber of the vessel to be treated with the left pedal (40) and then punctures it by injecting a small amount of sclerosing fluid into it.

During the end of the sclerosing fluid injection or after cessation of the same, an RF electric pulse is applied with the right pedal (39), aiming at the "burning" and definitive sclerosis of the punctured vessel. The previous injection of sclerosing serves two purposes, first to be sure of the correct placement of the needle tip inside the vessel, in which case its temporary disappearance is observed, since the contained sanguenele is replaced by sclerosing material. colorless; in another plane, of no less importance, it adds to the sclerosing effect of chemosclerosis, which acts on secondary telangiectatic branches, distant from the punctured vessel, to that of RF microsclerosis, which "burns" and definitively eliminates the main telangectatic branch. As we said earlier, it often takes several sessions of chemosclerosis to end a certain group of telangiectasias or small varicose veins; The simultaneous implementation of both methods significantly reduces the number of these sessions and, consequently, the patient's suffering.

Post-puncture bleeding, which is always present after the needle has been inserted into the skin and hinders the therapeutic procedure when chemosclerosis is performed on its own, or does not happen or occurs very little after the application of the radiofrequency electric pulse.

The pain can be greatly reduced if the doctor uses cold air anesthesia during the procedure. Cryoesthesia consists of applying, previously and simultaneously, to the site of dastelangiectasias or small-caliber varicose veins, cold air, with a temperature of up to 25 ° negative, partially or totally anesthetizing the dermal surface before puncture. The device for this purpose is already available on the market.

In places where chemosclerosis is contraindicated, such as on the face, RF micro-sclerosis should be used alone, replacing the sclerosing liquid with neutral liquid, such as distilled water for medical use, which preferably It should be mixed with a more concentrated anesthetic liquid from 3 to 10. Injected liquid, prior to the generation of the RF microsclerosis pulse, serves two purposes: to be sure of the correct location of the needle cannula tip and to anesthetize the vessel before cauterization.

Claims (24)

1. MICROSCLEROSIS RADIOFREQUENCE AND CHEMOSCLEROSIS NEEDLE NEEDLE, consisting of a metal cannula (27) and a plastic coupling tube (18), characterized in that the metal cannula (27) is mostly isolated externally by a insulating material microclayer (1). 2. MICROSCLEROSIS RADIOFREQUENCE AND CHEMOSCLEROSIS NEEDLE NEEDLE according to claim 1, characterized in that the metal cannula (27) is hollow, with lumen (14), and has a sharp beveled end (26). ). 3. MICRESCLEROSPHERE NEEDLE FOR RADIO-FREQUENCY AND CHEMOSCLEROSIS, according to claim 1, characterized in that the external insulation of the cannula-metal (1) is made by an insulating material, applied on a microclayer, with a thickness of less than 100 microns. 4. MICROSCLEROSIS RADIOFREQUENCE AND CHEMOSCLEROSIS NEEDLE NEEDLE according to claim 3, characterized in that the entire lower half of the bevel (6 '), as well as the entire outer circumference of the metal cannula (27), at a distance from the distal end of the metal cannula to a vertical line (F) which crosses upper half of the bevel (26), not covered by insulating material. 5. MICROSCLEROSPHERE NEEDLE FOR RADIO FREQUENCY AND CHEMOSCLEROSIS, according to claim 3, characterized in that the entire bevel surface (6 "), as well as the entire outer circumference of the metal cannula (27), at a distance from the extremity distal from the metal cannula until the vertical line (G) that crosses the upper edge of the bevel is not covered by insulating material. 6. MICROSCLEROSIS RADIOFREQUENCE AND CHEMOSCLEROSIS NEEDLE NEEDLE according to claim 3, characterized in that the entire bevel surface (6 "), as well as the entire outer circumference of the metal cannula (27), at a varying distance as measured by from the distal end of the metal cannula, 0.5 to 5 mm, is not covered with insulating material. 7. MICROSCLEROSIS RADIOFREQUENCE AND CHEMOSCLEROSIS NEEDLE NEEDLE according to claim 1, characterized in that the coupling barrel (18) passes through an electrical conductive material (12), which connects the proximal end of the metal cannula (11) to the Conductive electrical coating of the base of the plastic cannon (9). 8. MICROSCLEROSIS NEEDLE FOR RADIO FREQUENCY AND CHEMOSCLEROSIS according to claim 1, characterized in that the coupling barrel (18) is internally lined with electrical conductive material (9 '), which in turn is connected to the proximal end. the metal cannula (11 '). 9. RADIO-FREQUENCY AND CHYOSCLEROSIS MICROSCLEROSIS SYNDROME MADE OF PLASTIC MATERIAL, consisting of cylindrical drum (17), flanges (25), plunger rod (55), waterproof distal plunger (24), and a needle coupling nozzle (16), characterized by the fact that it offers means of electrical connection between the coupling nozzle for the needle (16) and a metal connector pin (19), located at the end of one of the flanges (25). 10. SYMCHEROSCLEROSIS DETERMINATION FOR EQUIMIO SCLEROSIS, according to claim 9, characterized in that the base of the syringe coupling nozzle is covered by electrical conductive material (21) which in turn connects to another electrical conductive material (20). ) following the cylindrical drum (17) to the end of one of the flanges (25), ending in a metal connector pin (19). 11. EQUIMIO SCLEROSE RADIO FREQUENCY SCREENING SYRINGE according to claim 10, characterized in that the electrically conductive metallic lining of the base of the syringe coupling nipple (21) extends to the outer surface of the syringe coupling nipple (21 '). 12. ELECTRIC RADIO FREQUENCY GENERATOR AND ACCESSORIES FOR MICROSCLEROSIS, consisting of radiofrequency generator unit (32), medical bracelet (53) and patient bracelet or anklet (52), electrical cables with connectors at their ends, and drive pedal (38), characterized in that it can be calibrated to generate coagulation intermittent pulses, to be used in monopolar and variable terpower mode, from 0 to 20 Watts. RADIO FREQUENCY ELECTRICAL GENERATOR AND ACCESSORIES according to Claim 12, characterized in that the controls (37) allow the power to be adjusted at intervals equal to or less than 0.1 Watt. RADIO FREQUENCY ELECTRICAL GENERATOR AND ACCESSORIES according to Claim 12, characterized in that the doctor's strap (53) has an externally located dual female electrical connector pin (48) on its side. RADIO FREQUENCY ELECTRICAL GENERATOR AND ACCESSORIES according to Claim 12, characterized in that the patient's wristband or anklet (52) is lined internally by malleable electrical conductor material (45) and has a connection between it and a female connector pin (44), located externally on its side. RADIO FREQUENCY ELECTRICAL GENERATOR AND ACCESSORIES according to Claim 15, characterized in that the patient's wristband or anklet (52) is replaced by a metal contact plate. 17. METHOD FOR PERFORMANCE DAMICOSCREROSIS BY RADIO FREQUENCY, ASSOCIATED WITH CHEMOSCLEROSIS, IN THE TREATMENT OF SMALL CALIBER VARIES, characterized by the fact that: use MICROCLESCLOSIS NEEDLE DECLARATIONS IN ACCORDANCE WITH MICROCLEROSIS 1; claims 9 to 11, using DERADIO FREQUENCY ELECTRIC GENERATOR AND ACCESSORIES according to claims 12 to 16. 18. METHOD FOR CARRYING OUT RADIO-FREQUENCY DAMICOSCLEROSIS, ASSOCIATED WITH CHEMOSCLEROSIS, according to claim 17, comprising the steps of: applying electrolytic gel to the patient's wristband or anklet (52) and connecting it to the patient by connecting it to the patient. the wire (46) to said bracelet (52) and to the ground of the radiofrequency generator (35), fill the inner barrel of the syringe (23) with sclerosing property, properly connect the microsclerosis needle (15) to the coupling bicode of the (16) wear the bracelet to the medical professional (53) by connecting the wires (49) (51) to the syringe and the positive pole of the radiofrequency generator (34); choose the vessel to be treated by selecting the preset or power setting with the left pedal (40), inject a small amount of sclerosing fluid, observing the momentary disappearance of the vessel, inject the appropriate amount of sclerosing fluid then apply the radiofrequency pulses by activating the right pedal (39). 19. METHOD FOR CARRYING OUT RADIO-FREQUENCY DAMICOSCLEROSIS, ASSOCIATED WITH CHEMOSCLEROSIS, according to claim 18, characterized in that, by injecting the small amount of sclerosing, one does not observe the momentary disappearance of the punctured vessel and interrupt a new process. puncture. A method for performing radiofrequency damsicrosclerosis associated with chemosclerosis according to claim 18, characterized in that the syringe (31) containing sclerosing fluid prior to use is cooled. 21. METHOD FOR CARRYING OUT RADIO-FREQUENCY DAMYCHRESCLEROSIS IN THE TREATMENT OF TELANGIECTASIAS AND SMALL CALIBER VARIES, characterized in that: using the MICROCLESHROSQUEROSE NEEDLE DEFERENCE, according to claims 1 through 8, according to claims 1 to 8; 9 to 11, using DERADIO FREQUENCY ELECTRIC GENERATOR AND ACCESSORIES according to claims 12 to 16. 22. METHOD FOR ISOLATED RADIO-FREQUENCY DAMICOSCLEROSIS IN THE TREATMENT OF SMALL CALIBER TELANGIETASIES AND VARIES, according to claim 21, comprising the steps of: applying to the inside of the patient's wristband or anklet (52) and electrolytic gel connect it to the patient by connecting the wire (46) to said bracelet (52) and the ground pole of the radiofrequency generator (35), filling the inside barrel of the syringe (23) with neutral liquid without sclerosing property; microsclerosis (15) on the syringe coupling nipple (16), wear the bracelet on the medical professional (53), connect the wires (49) (51) to the syringe and the positive pole of the radiofrequency generator (34), choose the vessel to be treated by selecting the preset or proper power setting with the left pedal (40), injecting a small amount of the neutral liquid, noticing the momentary disappearance of the vessel; the appropriate amount of neutral liquid, apply the radiofrequency pulses by operating the right pedal (39). 23. METHOD FOR ISOLATED RADIO-FREQUENCY DAMICROSCLEROSIS IN THE TREATMENT OF SMALL CALIBER TELANGIECTASIES AND DEPENDENTS, ACCORDING TO Claim 22, wherein, by injecting the small amount of neutral fluid, the disruption of the puncture with the unparalleled disruption of the vessel is not apparent. then proceed to a new puncture. 24. METHOD FOR THE ISOLATED RADIO-FREQUENCY DAMICOSCLEROSIS IN THE TREATMENT OF SMALL TELANGIECTASIES AND CALIBER VARIES, according to claim 22, characterized by the fact that aseringa (31) is cooled, containing neutral liquid, prior to its use.