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BRPI0906683A2 - método para medir e caracterizar microvesículas em fluidos corporais humanos - Google Patents

método para medir e caracterizar microvesículas em fluidos corporais humanos

Info

Publication number
BRPI0906683A2
BRPI0906683A2 BRPI0906683A BRPI0906683A2 BR PI0906683 A2 BRPI0906683 A2 BR PI0906683A2 BR PI0906683 A BRPI0906683 A BR PI0906683A BR PI0906683 A2 BRPI0906683 A2 BR PI0906683A2
Authority
BR
Brazil
Prior art keywords
measuring
human body
body fluids
microvesicles
characterizing
Prior art date
Application number
Other languages
English (en)
Inventor
Mariantonia Logozzi
Stefano Fais
Original Assignee
Hansabiomed Oue
Exosomics Siena S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hansabiomed Oue, Exosomics Siena S P A filed Critical Hansabiomed Oue
Publication of BRPI0906683A2 publication Critical patent/BRPI0906683A2/pt
Publication of BRPI0906683B1 publication Critical patent/BRPI0906683B1/pt
Publication of BRPI0906683B8 publication Critical patent/BRPI0906683B8/pt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G01N33/567Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • G01N33/56988HIV or HTLV
    • G01N33/5751
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/15Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
    • G01N2333/155Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
    • G01N2333/16HIV-1, HIV-2
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/18Togaviridae; Flaviviridae
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2828Prion diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
BRPI0906683A 2008-01-25 2009-01-26 método para medir e caracterizar microvesículas em fluidos corporais humanos BRPI0906683B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6252808P 2008-01-25 2008-01-25
US61/062.528 2008-01-25
US12/321,412 US8617806B2 (en) 2008-01-25 2009-01-21 Method to measure and characterize microvesicles in the human body fluids
US12/321,412 2009-01-21
PCT/EE2009/000002 WO2009092386A2 (en) 2008-01-25 2009-01-26 A new method to measure and characterize microvesicles in the human body fluids

Publications (3)

Publication Number Publication Date
BRPI0906683A2 true BRPI0906683A2 (pt) 2017-08-22
BRPI0906683B1 BRPI0906683B1 (pt) 2021-03-02
BRPI0906683B8 BRPI0906683B8 (pt) 2021-07-27

Family

ID=41064551

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0906683A BRPI0906683B8 (pt) 2008-01-25 2009-01-26 método para medir e caracterizar microvesículas em fluidos corporais humanos

Country Status (12)

Country Link
US (1) US8617806B2 (pt)
EP (1) EP2245458B1 (pt)
JP (1) JP5583600B2 (pt)
CN (1) CN102317778B (pt)
AU (1) AU2009207927B2 (pt)
BR (1) BRPI0906683B8 (pt)
CA (1) CA2713196C (pt)
ES (1) ES2613670T3 (pt)
MX (1) MX2010008164A (pt)
PL (1) PL2245458T3 (pt)
RU (1) RU2520741C2 (pt)
WO (1) WO2009092386A2 (pt)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2176665B1 (en) 2007-08-16 2016-03-02 The Royal Institution for the Advancement of Learning / McGill University Tumor cell-derived microvesicles
US20100255514A1 (en) 2007-08-16 2010-10-07 The Royal Institution For The Advancement Of Learning/Mcgill University Tumor cell-derived microvesicles
EP3239305A3 (en) * 2008-02-01 2017-11-29 The General Hospital Corporation Use of microvesicles in diagnosis and prognosis of medical diseases and conditions
US9487837B2 (en) * 2008-10-06 2016-11-08 Morehouse School Of Medicine Exosome-mediated diagnosis of hepatitis virus infections and diseases
US10545149B2 (en) * 2008-10-06 2020-01-28 Morehouse School Of Medicine Detection of HIV-related proteins in urine
CN102308004A (zh) 2008-10-30 2012-01-04 卡里斯生命科学卢森堡控股有限责任公司 评价rna图案的方法
GB2463401B (en) * 2008-11-12 2014-01-29 Caris Life Sciences Luxembourg Holdings S A R L Characterizing prostate disorders by analysis of microvesicles
WO2013022995A2 (en) * 2011-08-08 2013-02-14 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Biomarker compositions and methods
EP2475989A4 (en) 2009-09-09 2013-02-27 Gen Hospital Corp USE OF MICROVESICLES IN THE ANALYSIS OF KRAS MUTATIONS
EP2475988B1 (en) 2009-09-09 2018-11-14 The General Hospital Corporation Use of microvesicles in analyzing nucleic acid profiles
US20130203061A1 (en) * 2009-11-30 2013-08-08 Michael KLASS Methods and systems for isolating, storing, and analyzing vesicles
CN103237901B (zh) * 2010-03-01 2016-08-03 卡里斯生命科学瑞士控股有限责任公司 用于治疗诊断的生物标志物
EP2556172A4 (en) 2010-04-06 2013-10-30 Caris Life Sciences Luxembourg Holdings CIRCULATING BIOMARKERS FOR DISEASES
US20130323756A1 (en) 2010-07-07 2013-12-05 Aethlon Medical, Inc. Methods and compositions for quantifying exosomes
US20140045915A1 (en) 2010-08-31 2014-02-13 The General Hospital Corporation Cancer-related biological materials in microvesicles
AU2011316477A1 (en) * 2010-10-11 2013-05-02 Medsaic Pty Ltd Assay for disease detection
EP2638057B1 (en) 2010-11-10 2019-03-06 Exosome Diagnostics, Inc. Method for isolation of nucleic acid containing particles and extraction of nucleic acids therefrom
FR2973029B1 (fr) * 2011-03-23 2013-04-26 Centre Nat Rech Scient Complexes metalliques dinucleaires greffes, et leur utilisation en tant que capteurs de microparticules cellulaires
US9816998B2 (en) 2011-04-01 2017-11-14 Cornell University Circulating exosomes as diagnostic/prognostic indicators and therapeutic targets of melanoma and other cancers
WO2012162563A2 (en) 2011-05-24 2012-11-29 The Regents Of The University Of California Method for exosomal biomarker detection by electric field-induced release and measurement
EP2801822B1 (en) * 2011-12-22 2017-08-30 Theoria Science Inc. Exosome analysis method, reagent for use in analysis of exosome, and exosome analysis apparatus
JP6230027B2 (ja) * 2012-08-24 2017-11-15 国立大学法人 東京大学 エキソソームの分析方法、エキソソーム分析装置、抗体−エキソソーム複合体、及びエキソソーム電気泳動チップ
KR101933620B1 (ko) * 2012-09-18 2018-12-28 삼성전자주식회사 소포를 검출하기 위한 조성물, 키트 및 이를 이용하여 소포를 분석하는 방법
US9480714B2 (en) 2012-11-13 2016-11-01 Allan Yang Wu Methods and systems for processing exosomes
PT3677271T (pt) 2013-03-13 2023-05-31 Univ Miami Método de isolamento e purificação de microvesículas de sobrenadantes de cultura celular e fluidos biológicos
US10114015B2 (en) 2013-03-13 2018-10-30 Meso Scale Technologies, Llc. Assay methods
CN105392895B (zh) 2013-03-13 2019-07-26 中尺度技术有限责任公司 改进的测定方法
JP6210004B2 (ja) * 2013-04-09 2017-10-11 株式会社Jvcケンウッド 試料分析用デバイス及びエクソソームの捕捉方法
JPWO2015029979A1 (ja) * 2013-08-30 2017-03-02 国立大学法人 東京大学 エキソソームの分析方法、エキソソーム分析チップ、及びエキソソーム分析装置
JPWO2015045666A1 (ja) 2013-09-25 2017-03-09 国立大学法人 東京大学 流体デバイス、エキソソームの分析方法、生体分子分析方法及び生体分子検出方法
CN105723221B (zh) * 2013-11-06 2018-07-06 Jsr株式会社 分离方法、检测方法、信号测定方法、疾病的判定方法、疾病治疗药的药效评价方法、试剂盒以及液态组合物
EP3078889B1 (en) 2013-12-06 2019-09-18 The University of Tokyo Valve, fluid-controlling structure, fluid device, and method for manufacturing valve
CN112239774B (zh) * 2014-05-15 2024-12-03 中尺度技术有限责任公司 改进的测定方法
JP6650929B2 (ja) * 2014-06-06 2020-02-19 エクソソミクス・ソシエタ・ペル・アチオニEXOSOMICS S.p.A. 腫瘍関連エキソソーム用のバイオマーカーとしてのtm9sf4の使用
RU2556825C1 (ru) * 2014-09-15 2015-07-20 Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН) Способ получения экзосом из крови
US20160320390A1 (en) * 2015-05-01 2016-11-03 Morehouse School Of Medicine Compositions and methods for capturing exosomes
CN108271413A (zh) * 2015-05-20 2018-07-10 Jsr株式会社 分离方法、检测方法、信号测定方法、疾病的判定方法、药效评价方法、试剂盒、液态组合物以及检体稀释液
CA2988771A1 (en) 2015-06-09 2016-12-15 The Board Of Regents Of The University Of Texas System Diagnostic test for early stage cancer
JP6606916B2 (ja) 2015-08-21 2019-11-20 株式会社Jvcケンウッド エクソソームの捕捉方法
GB201518466D0 (en) * 2015-10-19 2015-12-02 Cizzle Biotechnology Ltd Use
CN106093412A (zh) * 2016-06-28 2016-11-09 叶瑞东 一种多肽分子在制备诊断急性脑梗死后微出血的试剂盒中的应用
US11614388B2 (en) 2016-10-13 2023-03-28 H.U. Group Research Institute G.K. Method for recovering extracellular vesicles
RU2682721C2 (ru) * 2016-11-17 2019-03-21 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Биологический микрочип для обнаружения опухолевых экзосом в сыворотке крови человека для диагностики колоректального рака
EP3570032B1 (en) * 2017-01-12 2023-04-12 THEORIA Science Inc. Method of examining subject's possibility of suffering from pancreatic cancer
CN106906294A (zh) * 2017-03-31 2017-06-30 浙江大学 一种胞外囊泡/脂质体的定量方法
CN107144688B (zh) * 2017-04-07 2018-09-11 浙江大学 Cd19阳性外泌体作为分子标记在制备肿瘤诊断试剂盒中的应用及试剂盒
EP3647786B1 (en) 2017-05-29 2023-03-08 National University Corporation Kobe University Base material for manufacturing sensor for analyzing detection target, sensor for analyzing detection target, method for analyzing detection target
DE102017005543A1 (de) * 2017-06-13 2018-12-13 Forschungszentrum Jülich GmbH Verfahren zum Nachweis von Extrazellulären Vesikeln in einer Probe
CN107907689A (zh) * 2017-10-10 2018-04-13 北京大学 外泌体蛋白cd5l的检测方法
KR101968046B1 (ko) * 2018-07-19 2019-04-11 (주) 바이오인프라생명과학 암의 조기 진단을 위한 복합 바이오마커
JP6677284B2 (ja) * 2018-10-09 2020-04-08 凸版印刷株式会社 分析対象物の検出方法及びラテラルフロー用テストストリップ
CN109991427A (zh) * 2019-04-08 2019-07-09 王延博 一种用于检测血清中外泌体表面蛋白标志物的试剂盒
CN110095604B (zh) * 2019-04-12 2022-03-18 南方医科大学南方医院 Caveolin-1蛋白阳性外泌体作为非小细胞肺癌诊断标志物的应用
US20220241702A1 (en) * 2019-05-24 2022-08-04 Sol Bio Corporation Affinity isolation system and method using switch-like binding reaction
WO2021107154A1 (ja) * 2019-11-29 2021-06-03 富士フイルム和光純薬株式会社 アルツハイマー型認知症又は軽度認知障害の診断を補助する方法、バイオマーカー、試薬キット及び装置
CN111537725A (zh) * 2020-05-29 2020-08-14 武汉大学 高效定量检测细胞外囊泡中pd-1水平的方法、elisa试剂盒及使用方法
DE102021208893B3 (de) 2021-08-13 2022-11-17 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Isolieren von Analyten unterschiedlicher Analyt-Klassen

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH081438B2 (ja) * 1986-05-13 1996-01-10 三洋化成工業株式会社 酵素免疫測定法
EP1004664A1 (en) * 1998-11-24 2000-05-31 Institut National De La Sante Et De La Recherche Medicale (Inserm) Compositions and methods using lactadherin or variants thereof
GB9927320D0 (en) * 1999-11-18 2000-01-12 Chiron Spa Exosome separation
US20040241176A1 (en) * 2000-04-27 2004-12-02 Ap Cells. Inc. Method of producing membrane vesicles
US6812023B1 (en) * 2000-04-27 2004-11-02 Anosys, Inc. Methods of producing membrane vesicles
US7442777B2 (en) * 2000-11-29 2008-10-28 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of CD63
US20030190602A1 (en) * 2001-03-12 2003-10-09 Monogen, Inc. Cell-based detection and differentiation of disease states
WO2003063690A2 (en) 2002-01-31 2003-08-07 Baylor College Of Medicine Secreted caveolin as a marker for prostate cancer
CA2453198A1 (en) * 2004-01-07 2005-07-07 Wei-Ping Min Quantification and generation of immune suppressive exosomes
JP2005237234A (ja) * 2004-02-25 2005-09-08 Japan Science & Technology Agency カベオリン抗原とその用途
JP2009535034A (ja) * 2006-04-28 2009-10-01 ユニバーシテイ・オブ・アイオワ・リサーチ・フアウンデーシヨン 哺乳動物細胞のパルボウイルス形質導入を調節若しくはウイルス感染を変えるための方法および化合物、ウイルス受容体若しくは共受容体の同定方法
US20120058492A1 (en) * 2008-01-25 2012-03-08 Hansabiomed Ou Method and a Kit To Detect Malignant Tumors and Provide a Prognosis

Also Published As

Publication number Publication date
JP2011510309A (ja) 2011-03-31
MX2010008164A (es) 2010-11-25
PL2245458T3 (pl) 2017-08-31
AU2009207927B2 (en) 2015-04-09
CA2713196A1 (en) 2009-07-30
RU2520741C2 (ru) 2014-06-27
CA2713196C (en) 2014-06-17
ES2613670T3 (es) 2017-05-25
EP2245458A2 (en) 2010-11-03
WO2009092386A3 (en) 2009-09-17
BRPI0906683B8 (pt) 2021-07-27
JP5583600B2 (ja) 2014-09-03
CN102317778A (zh) 2012-01-11
WO2009092386A8 (en) 2010-10-14
US20090220944A1 (en) 2009-09-03
BRPI0906683B1 (pt) 2021-03-02
AU2009207927A1 (en) 2009-07-30
CN102317778B (zh) 2015-05-13
WO2009092386A2 (en) 2009-07-30
EP2245458B1 (en) 2016-10-26
US8617806B2 (en) 2013-12-31
RU2010135526A (ru) 2012-02-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08G Application fees: restoration [chapter 8.7 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B25C Requirement related to requested transfer of rights

Owner name: HANSABIOMED OUE (EE)

Free format text: A FIM DE ATENDER A TRANSFERENCIA, REQUERIDA ATRAVES DA PETICAO NO 870190033511 DE 08/04/2019, E NECESSARIO APRESENTAR A TRADUCAO JURAMENTADA DO DOCUMENTO, ALEM DA GUIA DE CUMPRIMENTO DE EXIGENCIA.

B25A Requested transfer of rights approved

Owner name: EXOSOMICS SIENA S.P.A. (IT)

B25F Entry of change of name and/or headquarter and transfer of application, patent and certif. of addition of invention: change of name on requirement

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Free format text: A FIM DE ATENDER A ALTERACAO DE NOME REQUERIDA ATRAVES DA PETICAO NO 870200003634, DE 09/01/2020, E NECESSARIO APRESENTAR A TRADUCAO JURAMENTADA DO DOCUMENTO, ALEM DA GUIA DE CUMPRIMENTO DE EXIGENCIA.

B25D Requested change of name of applicant approved

Owner name: EXOSOMICS S.P.A. (IT)

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 02/03/2021, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/01/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

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B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2707 DE 22-11-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.