BRPI0822223A2 - Derivados de imidazo [1,2-alfa] piridina-2-carboxamidas, sua preparação e sua aplicação em terapêutica - Google Patents

Derivados de imidazo [1,2-alfa] piridina-2-carboxamidas, sua preparação e sua aplicação em terapêutica

Info

Publication number: BRPI0822223A2
Authority: BR; Brazil
Prior art keywords: imidazo; pyridine; alpha; preparation; therapeutic application
Prior art date: 2008-01-02

Application number

BRPI0822223-1A

Other languages

English (en)

Inventor

Jean-François Peyronel

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-01-02

Filing date

2008-12-31

Publication date

2015-06-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39739369&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0822223(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-12-31 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2015-06-23 Publication of BRPI0822223A2 publication Critical patent/BRPI0822223A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Addiction (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

BRPI0822223-1A 2008-01-02 2008-12-31 Derivados de imidazo [1,2-alfa] piridina-2-carboxamidas, sua preparação e sua aplicação em terapêutica BRPI0822223A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0800004A FR2925902B1 (fr)	2008-01-02	2008-01-02	DERIVES D'IMIDAZO°1,2-a!PYRIDINE-2-CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
PCT/FR2008/001835 WO2009112651A1 (fr)	2008-01-02	2008-12-31	Dérivés d'mtoazo[1,2-a]pyridine-2-carboxamides, leur préparation et leur application en thérapeutique

Publications (1)

Publication Number	Publication Date
BRPI0822223A2 true BRPI0822223A2 (pt)	2015-06-23

Family

ID=39739369

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0822223-1A BRPI0822223A2 (pt)	2008-01-02	2008-12-31	Derivados de imidazo [1,2-alfa] piridina-2-carboxamidas, sua preparação e sua aplicação em terapêutica

Country Status (21)

Country	Link
US (1)	US20100317656A1 (pt)
EP (1)	EP2225244A1 (pt)
JP (1)	JP2011508759A (pt)
KR (1)	KR20100109941A (pt)
CN (1)	CN101959886A (pt)
AR (1)	AR070073A1 (pt)
AU (1)	AU2008352728A1 (pt)
BR (1)	BRPI0822223A2 (pt)
CA (1)	CA2710797A1 (pt)
CL (1)	CL2008003927A1 (pt)
CO (1)	CO6331307A2 (pt)
EA (1)	EA201070817A1 (pt)
FR (1)	FR2925902B1 (pt)
IL (1)	IL206673A0 (pt)
MA (1)	MA32057B1 (pt)
MX (1)	MX2010007351A (pt)
PA (1)	PA8810101A1 (pt)
PE (1)	PE20091182A1 (pt)
TW (1)	TW200932746A (pt)
UY (1)	UY31588A1 (pt)
WO (1)	WO2009112651A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2925907B1 (fr) *	2008-01-02	2010-10-15	Sanofi Aventis	DERIVES DE 2-HETEROAROYL-IMIDAZO°1,2-a!PYRIDINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
PL2610255T3 (pl) *	2010-08-25	2016-08-31	Neopharm Co Ltd	Związki 1H-benzo[d]imidazol-5-ilowe i kompozycja do leczenia chorób zapalnych
WO2016133838A1 (en)	2015-02-20	2016-08-25	Rigel Pharmaceuticals, Inc.	Gdf-8 inhibitors
US11833156B2 (en)	2017-09-22	2023-12-05	Jubilant Epipad LLC	Heterocyclic compounds as pad inhibitors
WO2019077631A1 (en)	2017-10-18	2019-04-25	Jubilant Biosys Limited	IMIDAZO-PYRIDINE COMPOUNDS FOR USE AS PAD INHIBITORS
KR20200085836A (ko)	2017-11-06	2020-07-15	주빌런트 프로델 엘엘씨	Pd1/pd-l1 활성화 억제제로서의 피리미딘 유도체
CN107915752B (zh) *	2017-11-14	2018-09-18	牡丹江医学院	一种治疗白内障的药物及其制备方法
BR112020010322A2 (pt)	2017-11-24	2020-11-17	Jubilant Episcribe Llc	composto da fórmula i; composto da fórmula ia; composto da fórmula ib; processo de preparação de compostos da fórmula i; composição farmacêutica; método para o tratamento e/ou prevenção de várias doenças; uso dos compostos; método para o tratamento de câncer; e método para o tratamento e/ou prevenção de uma afecção mediada por prmt5 ou um distúrbio proliferativo ou câncer
CN112105610B (zh)	2018-03-13	2024-01-26	朱比连特普罗德尔有限责任公司	作为pd1/pd-l1相互作用/活化的抑制剂的双环化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8827189D0 (en) *	1988-11-21	1988-12-29	Fujisawa Pharmaceutical Co	2(1h)-quinolinone compounds processes for preparation thereof & pharmaceutical composition comprising same
US5716964A (en) *	1989-12-04	1998-02-10	G.D. Searle & Co.	Tetrazolyl substituted imidazo 1,2-a!pyridinylalkyl compounds for treatment of neurotoxic injury
FR2696177B1 (fr) *	1992-09-28	1995-05-12	Synthelabo	Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
GB0420519D0 (en) *	2004-09-15	2004-10-20	Novartis Ag	Organic compounds
WO2009023179A2 (en) *	2007-08-10	2009-02-19	Genelabs Technologies, Inc.	Nitrogen containing bicyclic chemical entities for treating viral infections
WO2009086303A2 (en) *	2007-12-21	2009-07-09	University Of Rochester	Method for altering the lifespan of eukaryotic organisms

2008
- 2008-01-02 FR FR0800004A patent/FR2925902B1/fr not_active Expired - Fee Related
- 2008-12-23 PA PA20088810101A patent/PA8810101A1/es unknown
- 2008-12-30 PE PE2008002195A patent/PE20091182A1/es not_active Application Discontinuation
- 2008-12-30 AR ARP080105778A patent/AR070073A1/es unknown
- 2008-12-30 CL CL2008003927A patent/CL2008003927A1/es unknown
- 2008-12-30 UY UY31588A patent/UY31588A1/es not_active Application Discontinuation
- 2008-12-31 CN CN2008801277688A patent/CN101959886A/zh active Pending
- 2008-12-31 AU AU2008352728A patent/AU2008352728A1/en not_active Abandoned
- 2008-12-31 EA EA201070817A patent/EA201070817A1/ru unknown
- 2008-12-31 WO PCT/FR2008/001835 patent/WO2009112651A1/fr not_active Ceased
- 2008-12-31 JP JP2010541084A patent/JP2011508759A/ja not_active Withdrawn
- 2008-12-31 TW TW097151675A patent/TW200932746A/zh unknown
- 2008-12-31 KR KR1020107017147A patent/KR20100109941A/ko not_active Withdrawn
- 2008-12-31 EP EP08873283A patent/EP2225244A1/fr not_active Ceased
- 2008-12-31 MX MX2010007351A patent/MX2010007351A/es not_active Application Discontinuation
- 2008-12-31 CA CA2710797A patent/CA2710797A1/fr not_active Abandoned
- 2008-12-31 BR BRPI0822223-1A patent/BRPI0822223A2/pt not_active IP Right Cessation
2010
- 2010-06-28 IL IL206673A patent/IL206673A0/en unknown
- 2010-07-01 US US12/828,372 patent/US20100317656A1/en not_active Abandoned
- 2010-07-02 CO CO10080876A patent/CO6331307A2/es not_active Application Discontinuation
- 2010-08-02 MA MA33055A patent/MA32057B1/fr unknown

Also Published As

Publication number	Publication date
EP2225244A1 (fr)	2010-09-08
EA201070817A1 (ru)	2011-02-28
IL206673A0 (en)	2010-12-30
FR2925902A1 (fr)	2009-07-03
CL2008003927A1 (es)	2010-02-12
AR070073A1 (es)	2010-03-10
UY31588A1 (es)	2009-08-03
MA32057B1 (fr)	2011-02-01
KR20100109941A (ko)	2010-10-11
CN101959886A (zh)	2011-01-26
PA8810101A1 (es)	2009-08-26
MX2010007351A (es)	2010-10-05
FR2925902B1 (fr)	2011-01-07
AU2008352728A1 (en)	2009-09-17
CA2710797A1 (fr)	2009-09-17
WO2009112651A1 (fr)	2009-09-17
CO6331307A2 (es)	2011-10-20
JP2011508759A (ja)	2011-03-17
TW200932746A (en)	2009-08-01
US20100317656A1 (en)	2010-12-16
PE20091182A1 (es)	2009-08-31

Publication	Publication Date	Title
ZA200901551B (en)	2010-06-30	2-aryl-6-phenylimidazo[1,2-alpha]pyridine derivatives, preparation thereof and therapeutic use thereof
BRPI0822223A2 (pt)	2015-06-23	Derivados de imidazo [1,2-alfa] piridina-2-carboxamidas, sua preparação e sua aplicação em terapêutica
BRPI0814510A2 (pt)	2015-02-03	Derivados de 6-cicloamino-3-(piridazin-4-il)imidazol[1,2-b]-piridazina, sua preparação e sua aplicação em terapêutica
BRPI0908999A8 (pt)	2016-07-12	derivados poli-substituídos de 2-aril-6-fenil-imidazo[1,2-a]piridinas, o respectivo preparo e respectiva aplicação em terapêutica
ZA201006728B (en)	2011-11-30	Polysubstituted 2-aryl-6-phenyl-imidazo[1,2-a]pyridine derivatives,and preparation and therapeutic use thereof
FR2945534B1 (fr)	2012-11-16	DERIVES DE CYCLOPENTAL[c]PYRROLE-2-CARBOXYLATES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
BRPI0908050A2 (pt)	2015-08-11	Furo-e tieno[3,2-c]piridinas
FR2933700B1 (fr)	2010-07-30	Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
BRPI0921947A2 (pt)	2018-10-16	formulações de proteína terapêutica
BRPI0924844A2 (pt)	2016-01-26	derivados de azacarbolinas 9h-pirrol[2,3-b:5,4-c']dipiridina, sua preparação e sua utilização terapêutica.
FR2917413B1 (fr)	2009-08-21	Derives de 7-alkynyl-1,8-naphthyridones, leur preparation et leur application en therapeutique
BRPI1011822A2 (pt)	2016-03-29	"compostos de 3-substituída-8-substituída-3h-imidazo[5,1-d][1,2,3,5-tetrazin-4-ona e sua aplicação"
BRPI0821992A2 (pt)	2015-06-23	Derivados de n-heterocíclico-imidazo[1,2-a]piridina-2-carboxamida s, respectivo preparo e respectiva aplicação em terapêutica
BRPI0814177A2 (pt)	2015-01-20	Derivados de 1-oxo-1,2-di-hidroisoquinoleína-5-carboxamidas e de 4-oxo-3,4-di-hidroquinazolina-8-carboxamidas, sua preparação e sua aplicação em terapêutica
IL198481A0 (en)	2010-02-17	Pyrrole derivatives, preparation use of the same in therapy
BRPI0923182A2 (pt)	2019-09-24	derivados de 6-cicloamino-2,3-di-piridinil-imidazo[1,2-b]piridazina, o respectivo preparo e a respectivo preparo e a respectiva aplicação terapêutica
BRPI0714317A2 (pt)	2014-06-24	Utilização de derivados de imidazo [ 1,2-alfa] piridina -21- carboxamidas em terapêutica.
BRPI0821991A2 (pt)	2015-06-23	Derivados de 2-heteroaroil-imidazo[1,2-alfa] piridina, sua preparação e sua aplicação em terapêutica
ZA201004520B (en)	2011-09-28	N-phenyl-imidazo[1,2-a]pyridine-2-carboxamide compounds,preparation thereof and therapeutic application thereof
ZA201004644B (en)	2011-11-30	"derivatives of 6-heterocyclic-imidazo[1,2-a]pyrroine-2-carboxamides,preparation thereof and therapeutic application thereof"
DK2421864T3 (da)	2014-11-10	1-PYRAZOLO[4,3-c]ISOQUINOLINDERIVATER, FREMSTILLING OG TERAPEUTISK ANVENDELSE HERAF
FR2930939B1 (fr)	2010-07-30	Derives de pyrrole, leur preparation et leur application en therapeutique
FR2919610B1 (fr)	2009-10-16	Derives de n-heteroaryl-carboxamides tricycliques,leur preparation et leur application en therapeutique
FR2911605B1 (fr)	2009-04-17	Derives de pyrrolopyridine-2-carbowamides, leur preparation et leur application en therapeutique
BRPI1015951A2 (pt)	2016-04-26	derivados de 1-alquil-cinolin-4-(1h)-ona substituídos, sua preparação e sua aplicação em terapêutica

Legal Events

Date	Code	Title	Description
2015-08-25	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES.
2016-05-10	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.