BRPI0812205A2 - Indução de fenótipo tolerogênico em células dendríticas maduras - Google Patents

Indução de fenótipo tolerogênico em células dendríticas maduras

Info

Publication number: BRPI0812205A2
Authority: BR; Brazil
Prior art keywords: dendritic cells; mature dendritic; tolerogenic phenotype; phenotype induction; induction
Prior art date: 2007-06-05

Application number

BRPI0812205-9A2A

Other languages

English (en)

Inventor

Jose M Carballido Herrara

Jan E De Vries

Ulf Korthaeuer

Maria Grazia Roncarolo

Silvia Adriana Gregori

Original Assignee

Novartis Ag

San Raffaele Centro Fond

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-05

Filing date

2008-06-03

Publication date

2014-11-25

2008-06-03 Application filed by Novartis Ag, San Raffaele Centro Fond filed Critical Novartis Ag

2014-11-25 Publication of BRPI0812205A2 publication Critical patent/BRPI0812205A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD45
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Transplantation (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

BRPI0812205-9A2A 2007-06-05 2008-06-03 Indução de fenótipo tolerogênico em células dendríticas maduras BRPI0812205A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP07109672		2007-06-05
PCT/EP2008/056851 WO2008148761A1 (en)	2007-06-05	2008-06-03	Induction of tolerogenic phenotype in mature dendritic cells

Publications (1)

Publication Number	Publication Date
BRPI0812205A2 true BRPI0812205A2 (pt)	2014-11-25

Family

ID=39721982

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0812205-9A2A BRPI0812205A2 (pt)	2007-06-05	2008-06-03	Indução de fenótipo tolerogênico em células dendríticas maduras

Country Status (17)

Country	Link
US (1)	US20100183602A1 (pt)
EP (1)	EP2160410A1 (pt)
JP (1)	JP2010529078A (pt)
KR (1)	KR20100035643A (pt)
CN (1)	CN101687928A (pt)
AU (1)	AU2008258646A1 (pt)
BR (1)	BRPI0812205A2 (pt)
CA (1)	CA2689570A1 (pt)
CL (1)	CL2008001620A1 (pt)
EA (1)	EA200901621A1 (pt)
IL (1)	IL202230A0 (pt)
MA (1)	MA31667B1 (pt)
MX (1)	MX2009013220A (pt)
TN (1)	TN2009000494A1 (pt)
TW (1)	TW200907061A (pt)
WO (1)	WO2008148761A1 (pt)
ZA (1)	ZA200908089B (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2347774B1 (en)	2005-12-13	2017-07-26	The President and Fellows of Harvard College	Scaffolds for cell transplantation
WO2009002401A2 (en)	2007-06-21	2008-12-31	President And Fellows Of Harvard College	Scaffolds for cell collection or elimination
US9370558B2 (en)	2008-02-13	2016-06-21	President And Fellows Of Harvard College	Controlled delivery of TLR agonists in structural polymeric devices
CN102006891B (zh)	2008-02-13	2017-04-26	哈佛学院董事会	连续的细胞程序化装置
US8728456B2 (en)	2009-07-31	2014-05-20	President And Fellows Of Harvard College	Programming of cells for tolerogenic therapies
EP2305277A1 (en) *	2009-09-18	2011-04-06	Forskarpatent I Syd AB	Use of tolerogenic dendritic cells in treatment and prevention of atherosclerosis
JP6104806B2 (ja)	2010-10-06	2017-03-29	プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ	材料に基づく細胞治療のための注射可能孔形成性ハイドロゲル
US9675561B2 (en)	2011-04-28	2017-06-13	President And Fellows Of Harvard College	Injectable cryogel vaccine devices and methods of use thereof
WO2012149358A1 (en)	2011-04-28	2012-11-01	President And Fellows Of Harvard College	Injectable preformed macroscopic 3-dimensional scaffolds for minimally invasive administration
CN117205331A (zh)	2011-04-29	2023-12-12	西莱克塔生物科技公司	用于降低抗体应答的致耐受性合成纳米载体
WO2012167230A1 (en)	2011-06-03	2012-12-06	President And Fellows Of Harvard College	In situ antigen-generating cancer vaccine
WO2013036294A1 (en) *	2011-09-06	2013-03-14	Selecta Biosciences, Inc.	Antigen-specific induced tolerogenic dendritic cells to reduce cytotoxic t lymphocyte responses
PT2838515T (pt)	2012-04-16	2020-02-25	Harvard College	Composições de sílica mesoporosa para modular respostas imunológicas
US10668053B2 (en)	2013-05-03	2020-06-02	Selecta Biosciences, Inc.	Tolerogenic synthetic nanocarriers to reduce or prevent anaphylaxis in response to a non-allergenic antigen
CN107073090A (zh)	2014-04-30	2017-08-18	哈佛学院董事会	结合的疫苗装置和杀死癌细胞的方法
KR102692773B1 (ko)	2014-09-07	2024-08-08	셀렉타 바이오사이언시즈, 인크.	유전자 편집 항-바이러스 전달 벡터 면역 반응을 약화시키기 위한 방법 및 조성물
HK1247861A1 (zh)	2015-01-30	2018-10-05	President And Fellows Of Harvard College	用於癌症治疗的肿瘤周围和肿瘤内部材料
HK1249452A1 (zh)	2015-04-10	2018-11-02	President And Fellows Of Harvard College	免疫细胞捕获装置及其制备和使用方法
CN109072197A (zh)	2016-02-06	2018-12-21	哈佛学院校长同事会	重塑造血巢以重建免疫
US11555177B2 (en)	2016-07-13	2023-01-17	President And Fellows Of Harvard College	Antigen-presenting cell-mimetic scaffolds and methods for making and using the same
CA3032505A1 (en)	2016-08-02	2018-02-08	President And Fellows Of Harvard College	Biomaterials for modulating immune responses
HUE072005T2 (hu)	2017-03-11	2025-10-28	Cartesian Therapeutics Inc	Gyulladásgátlókkal és immunszupresszánst tartalmazó szintetikus nanohordozókkal történõ kombinált kezeléssel összefüggõ eljárások és készítmények
CA3100349A1 (en) *	2018-05-17	2019-11-21	The Board Of Trustees Of The Leland Stanford Junior University	Receptor inhibition by phosphatase recruitment
WO2020061129A1 (en)	2018-09-19	2020-03-26	President And Fellows Of Harvard College	Compositions and methods for labeling and modulation of cells in vitro and in vivo
EP4034148A4 (en)	2019-09-23	2025-09-10	Harvard College	BIOMATERIAL-BASED ANTIGEN-FREE VACCINE AND ITS USE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0103389D0 (en) *	2001-02-12	2001-03-28	Novartis Ag	Organic compounds

2008
- 2008-06-03 AU AU2008258646A patent/AU2008258646A1/en not_active Abandoned
- 2008-06-03 JP JP2010510769A patent/JP2010529078A/ja active Pending
- 2008-06-03 BR BRPI0812205-9A2A patent/BRPI0812205A2/pt not_active IP Right Cessation
- 2008-06-03 CN CN200880023453A patent/CN101687928A/zh active Pending
- 2008-06-03 US US12/663,431 patent/US20100183602A1/en not_active Abandoned
- 2008-06-03 MX MX2009013220A patent/MX2009013220A/es not_active Application Discontinuation
- 2008-06-03 EA EA200901621A patent/EA200901621A1/ru unknown
- 2008-06-03 CA CA002689570A patent/CA2689570A1/en not_active Abandoned
- 2008-06-03 KR KR1020107000041A patent/KR20100035643A/ko not_active Withdrawn
- 2008-06-03 WO PCT/EP2008/056851 patent/WO2008148761A1/en not_active Ceased
- 2008-06-03 EP EP08760435A patent/EP2160410A1/en not_active Withdrawn
- 2008-06-04 TW TW097120768A patent/TW200907061A/zh unknown
- 2008-06-04 CL CL2008001620A patent/CL2008001620A1/es unknown
2009
- 2009-11-17 ZA ZA200908089A patent/ZA200908089B/xx unknown
- 2009-11-19 IL IL202230A patent/IL202230A0/en unknown
- 2009-11-26 TN TNP2009000494A patent/TN2009000494A1/fr unknown
- 2009-12-30 MA MA32461A patent/MA31667B1/fr unknown

Also Published As

Publication number	Publication date
MX2009013220A (es)	2010-04-09
JP2010529078A (ja)	2010-08-26
KR20100035643A (ko)	2010-04-05
ZA200908089B (en)	2010-07-28
IL202230A0 (en)	2010-06-16
MA31667B1 (fr)	2010-09-01
TW200907061A (en)	2009-02-16
EA200901621A1 (ru)	2010-06-30
WO2008148761A1 (en)	2008-12-11
CN101687928A (zh)	2010-03-31
AU2008258646A1 (en)	2008-12-11
CA2689570A1 (en)	2008-12-11
EP2160410A1 (en)	2010-03-10
TN2009000494A1 (en)	2011-03-31
US20100183602A1 (en)	2010-07-22
CL2008001620A1 (es)	2009-02-20

Publication	Publication Date	Title
BRPI0812205A2 (pt)	2014-11-25	Indução de fenótipo tolerogênico em células dendríticas maduras
EP2487146A4 (en)	2014-03-19	hONEYCOMB STRUCTURE
AP2015008431A0 (en)	2015-05-31	Improvements in feedwells
EP2069784A4 (en)	2009-11-18	IL-33 IN INFLAMMATORY DISEASE
EP2243939A4 (en)	2011-08-03	TURBO
GB0805203D0 (en)	2008-04-30	Improvements in prepregs
GB0802154D0 (en)	2008-03-12	Improvements in electrical means
GB2445978B (en)	2009-02-25	Improvements in battery chargers
ZA201108848B (en)	2013-02-27	Improvements in efficiency
GB2459082B (en)	2010-04-21	Improvements in artificial lift mechanisms
GB0816516D0 (en)	2008-10-15	3 in 1 power glove
GB2458569B (en)	2010-10-20	Improvements in and relating to cloches
EP2476111A4 (en)	2013-09-25	IMPROVEMENTS IN THE CONSTRUCTION OF PIANO
GB0903527D0 (en)	2009-04-08	Improvements in hinges
GB0823515D0 (en)	2009-01-28	Improvements in bivvies
HK1141305A (en)	2010-11-05	Induction of tolerogenic phenotype in mature dendritic cells
GB0819309D0 (en)	2008-11-26	Eco power moduel series 2
GB201005441D0 (en)	2010-05-19	Improvements in wheelchairs
GB0904880D0 (en)	2009-05-06	Gravity power renewed
GB0822250D0 (en)	2009-01-14	Improvements in and relating to karabiners
AU5474P (en)	2009-05-27	B in B Agapanthus hybrid
GB0813316D0 (en)	2008-08-27	Improvements in or relating to power adapters
TWM371992U (en)	2010-01-01	Two in one electric connection
GB0809800D0 (en)	2008-07-09	Improvements in inserts
GB0820026D0 (en)	2008-12-10	Improvements in pinch-bolt type connections

Legal Events

Date	Code	Title	Description
2015-08-25	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.
2016-05-10	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.