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BRPI0810179B8 - composições de oligoguluronato e galacturonato e usos dos mesmos - Google Patents

composições de oligoguluronato e galacturonato e usos dos mesmos

Info

Publication number
BRPI0810179B8
BRPI0810179B8 BRPI0810179A BRPI0810179A BRPI0810179B8 BR PI0810179 B8 BRPI0810179 B8 BR PI0810179B8 BR PI0810179 A BRPI0810179 A BR PI0810179A BR PI0810179 A BRPI0810179 A BR PI0810179A BR PI0810179 B8 BRPI0810179 B8 BR PI0810179B8
Authority
BR
Brazil
Prior art keywords
composition
galacturonate
oligoguluronate
guluronate
compositions
Prior art date
Application number
BRPI0810179A
Other languages
English (en)
Inventor
Taylor Catherine
Ingar Draget Kurt
Asmund Smidsrod Olav
Original Assignee
Ntnu Tech Transfer As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ntnu Tech Transfer As filed Critical Ntnu Tech Transfer As
Publication of BRPI0810179A2 publication Critical patent/BRPI0810179A2/pt
Publication of BRPI0810179B1 publication Critical patent/BRPI0810179B1/pt
Publication of BRPI0810179B8 publication Critical patent/BRPI0810179B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Otolaryngology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

composições de oligo-guluronato e galacturonato. a presente invenção refere-se a uma composição farmacêutica compreendendo um fármaco macromolecular e um oligoguluronato ou oligogalacturonato, por exemplo, tendo um grau médio numérico de polimerização na faixa de 5 a 18, uma fração de guluronato ( ou galacturonato) (fg) de pelo menos 0,80, uma fração de manuronato (fm) de não mais do que 0,20, tendo pelo meno 95% em mol com um grau de polimerização menor do que 20. a composição pode ser usada em um método de tratamento que compreende administrar a composição a uma superfície da mucosa em um indivíduo administrar a composição a um superfície da mucosa em um individuo vertebrado humano não humano.
BRPI0810179A 2007-04-12 2008-04-11 composições de oligoguluronato e galacturonato e usos dos mesmos BRPI0810179B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0707096.4A GB0707096D0 (en) 2007-04-12 2007-04-12 Method
PCT/GB2008/001287 WO2008125828A2 (en) 2007-04-12 2008-04-11 Oligo-guluronate and galacturonate compositions

Publications (3)

Publication Number Publication Date
BRPI0810179A2 BRPI0810179A2 (pt) 2014-12-30
BRPI0810179B1 BRPI0810179B1 (pt) 2019-12-10
BRPI0810179B8 true BRPI0810179B8 (pt) 2021-05-25

Family

ID=38116633

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0810179A BRPI0810179B8 (pt) 2007-04-12 2008-04-11 composições de oligoguluronato e galacturonato e usos dos mesmos

Country Status (14)

Country Link
US (1) US8841279B2 (pt)
EP (2) EP2500025B1 (pt)
JP (2) JP5649443B2 (pt)
KR (2) KR101472245B1 (pt)
CN (1) CN101711159B (pt)
AU (1) AU2008237710B2 (pt)
BR (1) BRPI0810179B8 (pt)
CA (2) CA2683914C (pt)
DK (2) DK2155211T3 (pt)
EA (1) EA018776B1 (pt)
ES (2) ES2553962T3 (pt)
GB (1) GB0707096D0 (pt)
MX (2) MX352972B (pt)
WO (1) WO2008125828A2 (pt)

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GB0909529D0 (en) 2009-06-03 2009-07-15 Algipharma Ipr As Alginate oligomers for the inhibition of microbial adherence to surfaces
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US11723914B2 (en) 2017-03-28 2023-08-15 The University Of North Carolina At Chapel Hill Nitric oxide-releasing polyaminoglycosides as biodegradable antibacterial scaffolds and methods pertaining thereto
WO2019099525A1 (en) 2017-11-15 2019-05-23 The University Of North Carolina At Chapel Hill Nitric oxide-releasing hyperbranched compounds as antibacterial scaffolds and methods pertaining thereto
JP7565588B2 (ja) 2018-03-06 2024-10-11 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 生分解性の抗菌性足場としての一酸化窒素放出性シクロデキストリンおよびそれに関する方法
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CA3124673A1 (en) 2018-12-28 2020-07-02 The University Of North Carolina At Chapel Hill Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto
US11684597B2 (en) 2019-01-28 2023-06-27 The United States Of America As Represented By The Secretary Of The Army Administration of tailored feedstock to increase nitro-containing amphenicol antibiotic susceptibility
GB201908639D0 (en) 2019-06-17 2019-07-31 Algipharma Ipr As Use of alginate oligomers in the anticoagulation therapy of subjects at risk of blood clots which have an abnormally dense microstructure
CN121001710A (zh) 2022-12-30 2025-11-21 阿尔吉法玛公司 提高口服多肽治疗剂的全身生物利用度的组合物和方法
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Also Published As

Publication number Publication date
CA2683914C (en) 2013-08-13
WO2008125828A3 (en) 2009-06-04
KR20130106446A (ko) 2013-09-27
EA200901299A1 (ru) 2010-06-30
JP5649443B2 (ja) 2015-01-07
EP2155211B1 (en) 2015-08-26
JP2010523636A (ja) 2010-07-15
EP2500025A1 (en) 2012-09-19
CN101711159A (zh) 2010-05-19
US8841279B2 (en) 2014-09-23
WO2008125828A2 (en) 2008-10-23
CA2683914A1 (en) 2008-10-23
EA018776B1 (ru) 2013-10-30
GB0707096D0 (en) 2007-05-23
MX2009010889A (es) 2009-10-28
US20100152122A1 (en) 2010-06-17
CA2817754C (en) 2014-12-09
AU2008237710B2 (en) 2014-02-06
JP2014129401A (ja) 2014-07-10
EP2155211A2 (en) 2010-02-24
ES2655102T3 (es) 2018-02-16
DK2500025T3 (en) 2018-01-15
DK2155211T3 (en) 2015-12-14
AU2008237710A1 (en) 2008-10-23
KR101336459B1 (ko) 2013-12-04
CA2817754A1 (en) 2008-10-23
MX352972B (es) 2017-12-15
EP2500025B1 (en) 2017-10-18
KR20100016492A (ko) 2010-02-12
BRPI0810179B1 (pt) 2019-12-10
CN101711159B (zh) 2012-06-27
KR101472245B1 (ko) 2014-12-11
ES2553962T3 (es) 2015-12-15
BRPI0810179A2 (pt) 2014-12-30

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