BRPI0810179A2 - Composições de oligo-guluronato e galacturonato - Google Patents
Composições de oligo-guluronato e galacturonatoInfo
- Publication number
- BRPI0810179A2 BRPI0810179A2 BRPI0810179-5A2A BRPI0810179A BRPI0810179A2 BR PI0810179 A2 BRPI0810179 A2 BR PI0810179A2 BR PI0810179 A BRPI0810179 A BR PI0810179A BR PI0810179 A2 BRPI0810179 A2 BR PI0810179A2
- Authority
- BR
- Brazil
- Prior art keywords
- guluronate
- galacturonate
- oligo
- compositions
- Prior art date
Links
- AEMOLEFTQBMNLQ-BKBMJHBISA-N alpha-D-galacturonic acid Chemical compound O[C@H]1O[C@H](C(O)=O)[C@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-BKBMJHBISA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Otolaryngology (AREA)
- Pregnancy & Childbirth (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0707096.4A GB0707096D0 (en) | 2007-04-12 | 2007-04-12 | Method |
| PCT/GB2008/001287 WO2008125828A2 (en) | 2007-04-12 | 2008-04-11 | Oligo-guluronate and galacturonate compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0810179A2 true BRPI0810179A2 (pt) | 2014-12-30 |
| BRPI0810179B1 BRPI0810179B1 (pt) | 2019-12-10 |
| BRPI0810179B8 BRPI0810179B8 (pt) | 2021-05-25 |
Family
ID=38116633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0810179A BRPI0810179B8 (pt) | 2007-04-12 | 2008-04-11 | composições de oligoguluronato e galacturonato e usos dos mesmos |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8841279B2 (pt) |
| EP (2) | EP2500025B1 (pt) |
| JP (2) | JP5649443B2 (pt) |
| KR (2) | KR101472245B1 (pt) |
| CN (1) | CN101711159B (pt) |
| AU (1) | AU2008237710B2 (pt) |
| BR (1) | BRPI0810179B8 (pt) |
| CA (2) | CA2683914C (pt) |
| DK (2) | DK2155211T3 (pt) |
| EA (1) | EA018776B1 (pt) |
| ES (2) | ES2553962T3 (pt) |
| GB (1) | GB0707096D0 (pt) |
| MX (2) | MX352972B (pt) |
| WO (1) | WO2008125828A2 (pt) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2430881B (en) | 2005-10-06 | 2010-10-13 | Ntnu Technology Transfer As | Oligoelectrolyte polyols for the treatment of mucosal hyperviscosity |
| GB0707096D0 (en) | 2007-04-12 | 2007-05-23 | Ntnu Technology Transfer As | Method |
| SI2268142T1 (sl) * | 2007-11-27 | 2017-09-29 | Algipharma As | Uporaba alginiranih oligomerov v boju proti biofilmom |
| GB0904942D0 (en) * | 2009-03-23 | 2009-05-06 | Ntnu Technology Transfer As | Composition |
| GB0904941D0 (en) * | 2009-03-23 | 2009-05-06 | Ntnu Technology Transfer As | Composition |
| RU2586253C2 (ru) | 2009-06-03 | 2016-06-10 | АльгиФарма АС | Обработка акинетобактерий альгинатными олигомерами и антибиотиками |
| GB0909529D0 (en) | 2009-06-03 | 2009-07-15 | Algipharma Ipr As | Alginate oligomers for the inhibition of microbial adherence to surfaces |
| GB0909557D0 (en) | 2009-06-03 | 2009-07-15 | Algipharma Ipr As | Anti-microbial alginate oligomers |
| JO3676B1 (ar) * | 2009-07-27 | 2020-08-27 | Arc Medical Devices Inc | مركبات صيدلانية تضم فوكانات معدلة وطرق تتعلق بها |
| GB201116010D0 (en) | 2011-09-15 | 2011-10-26 | Algipharma As | Use of alginate oligomers to enhance the effects of antifungal agents |
| GB201322777D0 (en) | 2013-12-20 | 2014-02-05 | Algipharma As | Use of alginate oligomers as blood anticoagulants |
| JP2017501221A (ja) * | 2013-12-23 | 2017-01-12 | ノルウェージャン ユニバーシティ オブ サイエンス アンド テクノロジー(エヌティーエヌユー) | がん治療におけるオリゴウロン酸塩の使用 |
| CN106029079A (zh) * | 2014-02-28 | 2016-10-12 | 阿尔吉法玛公司 | 藻酸盐低聚物在治疗囊性纤维化和与缺陷性cftr离子通道功能相关的其它疾病中的应用 |
| FR3024358B1 (fr) * | 2014-08-01 | 2017-11-10 | Soc De Courtage Et De Diffusion Codif Int | Compositions cosmetiques et complements alimentaires neuro-protecteurs comprenant de l'oligoalginate ayant un degre de polymerisation de 10 pour lutter contre le vieillissement de la peau. |
| GB201415381D0 (en) | 2014-08-29 | 2014-10-15 | Algipharma As | Inhalable powder formulations of alginate oligomers |
| GB201504878D0 (en) * | 2015-03-23 | 2015-05-06 | Algipharma As | Use of alginate oligomers and CFTR modulators in the treatment of conditions associated with CFTR dysfuntion |
| GB201517639D0 (en) | 2015-10-06 | 2015-11-18 | Algipharma As | Use of alginate oligomers to treat or prevent microbial overgrowth in the intestinal tract |
| AU2018205823A1 (en) | 2017-01-03 | 2019-07-18 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto |
| US11723914B2 (en) | 2017-03-28 | 2023-08-15 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing polyaminoglycosides as biodegradable antibacterial scaffolds and methods pertaining thereto |
| WO2019099525A1 (en) | 2017-11-15 | 2019-05-23 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing hyperbranched compounds as antibacterial scaffolds and methods pertaining thereto |
| JP7565588B2 (ja) | 2018-03-06 | 2024-10-11 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 生分解性の抗菌性足場としての一酸化窒素放出性シクロデキストリンおよびそれに関する方法 |
| GB201812473D0 (en) | 2018-07-31 | 2018-09-12 | Algipharma As | Method for the qualitative and quantitative detection of alginate oligomers in body fluids |
| CA3124673A1 (en) | 2018-12-28 | 2020-07-02 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto |
| US11684597B2 (en) | 2019-01-28 | 2023-06-27 | The United States Of America As Represented By The Secretary Of The Army | Administration of tailored feedstock to increase nitro-containing amphenicol antibiotic susceptibility |
| GB201908639D0 (en) | 2019-06-17 | 2019-07-31 | Algipharma Ipr As | Use of alginate oligomers in the anticoagulation therapy of subjects at risk of blood clots which have an abnormally dense microstructure |
| CN121001710A (zh) | 2022-12-30 | 2025-11-21 | 阿尔吉法玛公司 | 提高口服多肽治疗剂的全身生物利用度的组合物和方法 |
| WO2026008878A1 (en) | 2024-07-04 | 2026-01-08 | Algipharma As | Antimycotic polyene-alginate oligomer conjugates |
Family Cites Families (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL297511A (pt) | 1956-12-20 | |||
| FR7576M (pt) | 1968-03-27 | 1970-01-05 | ||
| HU172831B (hu) * | 1976-03-31 | 1978-12-28 | Egyt Gyogyszervegyeszeti Gyar | Sposob poluchenija kompleksov oligo- i poligalakturonnyk kislot s ionami zhiznenno vazhnykh metallov |
| JPS6176413A (ja) | 1984-09-21 | 1986-04-18 | Junzo Sunamoto | 吸水性高分子によりカプセル化されたリポソ−ムの製造法 |
| DD268865A1 (de) | 1987-01-16 | 1989-06-14 | Adw Ddr | Verfahren zur herstellung eines pharmazeutischen praeparates |
| US4898852A (en) | 1987-06-02 | 1990-02-06 | Walsh William E | Cyclopolgalcturonic acid composition and treatment |
| US4855128A (en) | 1988-01-14 | 1989-08-08 | Warner-Lambert Company | Saccharide inhibition of dental plaque |
| JP2641472B2 (ja) | 1988-01-30 | 1997-08-13 | 日本レダリー株式会社 | 感染症治療剤 |
| JPH05502863A (ja) | 1989-12-05 | 1993-05-20 | トランセル・コーポレイション | 生体内適用および埋め込み用コーティング組成物同種グルロン酸―アルギン酸塩およびその使用方法 |
| US5459054A (en) * | 1989-12-05 | 1995-10-17 | Neocrin Company | Cells encapsulated in alginate containing a high content of a- l- guluronic acid |
| WO1991011205A1 (en) | 1990-01-23 | 1991-08-08 | Trancel Corporation | Mannuronic acid containing alginate wound healing composition and method |
| US5166137A (en) | 1991-03-27 | 1992-11-24 | Nobipols Forskningsstiftelse | Guluronic acid polymers and use of same for inhibition of cytokine production |
| US5460957A (en) * | 1992-04-28 | 1995-10-24 | Maruha Corporation | Calcium alginate oligosaccharide and method for producing the same from potassium or sodium alginate |
| HU213872B (en) | 1993-09-08 | 1997-11-28 | Mta Koezponti Kemiai Kutato In | Oligo- and polygalacturonate mixed complex, pharmaceutical and food compositions containing them, further process for preparing these compounds |
| DE4330773A1 (de) * | 1993-09-10 | 1995-03-16 | Laevosan Gmbh & Co Kg | Blockierung der Anlagerung von Keimen an menschliche Zellen |
| JP2828391B2 (ja) * | 1993-10-29 | 1998-11-25 | 東燃株式会社 | オリゴ糖を表面に有するリポソーム |
| AUPM322393A0 (en) | 1993-12-24 | 1994-01-27 | Austin Research Institute, The | Mucin carbohydrate compounds and their use in immunotherapy |
| US5795587A (en) * | 1995-01-23 | 1998-08-18 | University Of Pittsburgh | Stable lipid-comprising drug delivery complexes and methods for their production |
| CA2235069C (en) * | 1995-10-19 | 2010-12-14 | Advanced Reproduction Technologies, Inc. | Methods and compositions to improve germ cell and embryo survival and function |
| JP3512553B2 (ja) | 1996-01-30 | 2004-03-29 | ポーラ化成工業株式会社 | 便秘抑制剤及びそれを含有する組成物 |
| FR2747045B1 (fr) | 1996-04-05 | 1998-06-26 | Hooreman Michel | Nouveau medicament optimisant la viscosite des mucus et ameliorant le fonctionnement de l'intestin |
| NO305441B1 (no) | 1996-07-12 | 1999-05-31 | Norsk Hydro As | Anvendelse av G-blokk polysakkarider |
| WO1998013024A2 (en) | 1996-09-27 | 1998-04-02 | Hyal Pharmaceutical Corporation | Hyaluronic drug delivery system |
| US20070185032A1 (en) * | 1996-12-11 | 2007-08-09 | Praecis Pharmaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
| NO305033B1 (no) * | 1997-05-09 | 1999-03-22 | Algipharma As | Fremgangsmate for fremstilling av uronsyreblokker fra alginat |
| US6339075B1 (en) * | 1997-06-30 | 2002-01-15 | The University Of British Columbia | Use of dextran and other polysaccharides to improve mucus clearance |
| KR100219918B1 (ko) | 1997-07-03 | 1999-09-01 | 김윤 | 대장선택적 약물전달용 조성물 |
| JP3849144B2 (ja) * | 1997-12-31 | 2006-11-22 | ソニー株式会社 | 符号化データ出力装置及び方法並びに符号化データ制御装置及び方法 |
| JP3932679B2 (ja) * | 1998-07-21 | 2007-06-20 | セイコーエプソン株式会社 | ポリグルロン酸の製造法 |
| US6290987B1 (en) | 1998-09-27 | 2001-09-18 | Generex Pharmaceuticals, Inc. | Mixed liposome pharmaceutical formulation with amphiphiles and phospholipids |
| US20040224922A1 (en) * | 1999-08-26 | 2004-11-11 | Malcolm King | Use of charged dextran as a mucoactive agent and methods and pharmaceutical compositions relating thereto |
| HK1047246A1 (zh) | 1999-08-26 | 2003-02-14 | 艾伯塔大学理事会 | 带电葡聚糖作为粘液活性剂的用途及有关方法和药物组合物 |
| US6458387B1 (en) | 1999-10-18 | 2002-10-01 | Epic Therapeutics, Inc. | Sustained release microspheres |
| JP2001155905A (ja) * | 1999-11-24 | 2001-06-08 | Nec Corp | 半導体装置およびトリミング方法ならびに記録媒体 |
| US7785625B2 (en) * | 2000-01-14 | 2010-08-31 | Lg Life Sciences, Limited | Lipophilic-coated microparticle containing a protein drug and formulation comprising same |
| KR100501584B1 (ko) * | 2000-02-03 | 2005-07-18 | (주)케이비피 | 저분자 폴리만유로네이트의 제조방법, 혈청지질개선제로서의 이의 신규 용도 및 이를 함유하는 기능성식품 및 건강 보조 식품 |
| DE10006989A1 (de) * | 2000-02-16 | 2001-08-23 | Nutricia Nv | Antiadhäsive Kohlenhydratmischung |
| DE60143566D1 (de) | 2000-03-07 | 2011-01-13 | Rush Presbyterian St Luke | Zusammensetzungen und deren Verwendung zum Abfangen und Inaktivieren pathogener Mikroben und Spermatozoen |
| WO2001072278A2 (en) | 2000-03-30 | 2001-10-04 | Generex Pharmaceuticals Inc. | Method for administering insulin to the buccal region |
| DE10019076A1 (de) * | 2000-04-06 | 2001-10-18 | Lang Christine | Verwendung von Polygalakturoniden als Lebensmittelzusatzstoffe |
| JP2002338493A (ja) | 2000-10-23 | 2002-11-27 | Genaera Corp | ムチン合成インヒビター |
| DE10057976B4 (de) | 2000-11-22 | 2005-02-03 | Südzucker AG Mannheim/Ochsenfurt | Verfahren zur Herstellung von Pektinhydrolyseprodukten |
| US6440314B1 (en) * | 2001-01-03 | 2002-08-27 | Vulcan Chemical Technologies, Inc. | Method for destroying chlorite in solution |
| ITMI20010347A1 (it) | 2001-02-21 | 2002-08-21 | Grisotech S A | Complessi di immunoglobuline e polisaccaridi per assorbimento orale etrans-mucosale |
| US6610331B1 (en) * | 2002-05-30 | 2003-08-26 | Scott M. Sweazy | Fertility kit |
| JP2005145885A (ja) * | 2003-11-14 | 2005-06-09 | Japan Science & Technology Agency | アルギン酸オリゴマーからなる免疫機構賦活剤 |
| ES2328048T3 (es) | 2004-03-12 | 2009-11-06 | Biodel, Inc. | Composiciones de insulina con absorcion mejorada. |
| US7745651B2 (en) * | 2004-06-07 | 2010-06-29 | Protiva Biotherapeutics, Inc. | Cationic lipids and methods of use |
| JP2006028041A (ja) | 2004-07-13 | 2006-02-02 | Ltt Bio-Pharma Co Ltd | 核酸含有ナノ粒子 |
| EP1714660A1 (en) | 2005-04-21 | 2006-10-25 | N.V. Nutricia | Uronic acid and probiotics |
| US7621036B2 (en) | 2005-06-21 | 2009-11-24 | Cardiomems, Inc. | Method of manufacturing implantable wireless sensor for in vivo pressure measurement |
| EP1745705A1 (en) | 2005-07-20 | 2007-01-24 | N.V. Nutricia | Process for preparing uronic acid oligosaccharides by extrusion |
| GB2430881B (en) * | 2005-10-06 | 2010-10-13 | Ntnu Technology Transfer As | Oligoelectrolyte polyols for the treatment of mucosal hyperviscosity |
| AU2006302744B8 (en) | 2005-10-21 | 2011-02-10 | Living Cell Products Pty Limited | Encapsulation system |
| GB0707096D0 (en) | 2007-04-12 | 2007-05-23 | Ntnu Technology Transfer As | Method |
| US20110130444A1 (en) | 2007-05-04 | 2011-06-02 | Stefan Moisyadi | Methods and compositions for targeted delivery of gene therapeutic vectors |
| JP2011520962A (ja) | 2008-05-19 | 2011-07-21 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 新規カチオン性脂質を含む方法及び組成物 |
-
2007
- 2007-04-12 GB GBGB0707096.4A patent/GB0707096D0/en not_active Ceased
-
2008
- 2008-04-11 DK DK08736951.8T patent/DK2155211T3/en active
- 2008-04-11 ES ES08736951.8T patent/ES2553962T3/es active Active
- 2008-04-11 KR KR1020137022922A patent/KR101472245B1/ko active Active
- 2008-04-11 JP JP2010502572A patent/JP5649443B2/ja active Active
- 2008-04-11 CA CA2683914A patent/CA2683914C/en active Active
- 2008-04-11 WO PCT/GB2008/001287 patent/WO2008125828A2/en not_active Ceased
- 2008-04-11 AU AU2008237710A patent/AU2008237710B2/en active Active
- 2008-04-11 CN CN2008800196645A patent/CN101711159B/zh active Active
- 2008-04-11 CA CA2817754A patent/CA2817754C/en active Active
- 2008-04-11 MX MX2014005931A patent/MX352972B/es unknown
- 2008-04-11 US US12/595,818 patent/US8841279B2/en active Active
- 2008-04-11 ES ES12161928.2T patent/ES2655102T3/es active Active
- 2008-04-11 EP EP12161928.2A patent/EP2500025B1/en active Active
- 2008-04-11 EP EP08736951.8A patent/EP2155211B1/en active Active
- 2008-04-11 KR KR1020097023647A patent/KR101336459B1/ko active Active
- 2008-04-11 BR BRPI0810179A patent/BRPI0810179B8/pt not_active IP Right Cessation
- 2008-04-11 DK DK12161928.2T patent/DK2500025T3/en active
- 2008-04-11 EA EA200901299A patent/EA018776B1/ru unknown
- 2008-04-11 MX MX2009010889A patent/MX2009010889A/es active IP Right Grant
-
2014
- 2014-03-05 JP JP2014042608A patent/JP2014129401A/ja active Pending
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