BRPI0818324A2 - formulações líquidas de lh - Google Patents

formulações líquidas de lh

Info

Publication number: BRPI0818324A2
Authority: BR; Brazil
Prior art keywords: liquid formulations; formulations; liquid
Prior art date: 2007-11-01

Application number

BRPI0818324A

Other languages

English (en)

Inventor

Del Rio Alessandra

Samaritani Fabrizio

Richard Joel

Agostinetto Rita

Original Assignee

Merck Serono Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-11-01

Filing date

2008-10-29

Publication date

2017-05-16

2008-10-29 Application filed by Merck Serono Sa filed Critical Merck Serono Sa

2017-05-16 Publication of BRPI0818324A2 publication Critical patent/BRPI0818324A2/pt

2019-12-24 Publication of BRPI0818324B1 publication Critical patent/BRPI0818324B1/pt

2021-05-25 Publication of BRPI0818324B8 publication Critical patent/BRPI0818324B8/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Reproductive Health (AREA)
Oil, Petroleum & Natural Gas (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Dermatology (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

BRPI0818324A 2007-11-01 2008-10-29 formulação líquida contendo hormônio luteinizante (lh) ou uma variante do mesmo, seu uso, sua forma de apresentação, processo para a sua preparação e composição farmacêutica BRPI0818324B8 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP07119832		2007-11-01
US448107P	2007-11-28	2007-11-28
PCT/EP2008/064679 WO2009056569A1 (en)	2007-11-01	2008-10-29	Lh liquid formulations

Publications (3)

Publication Number	Publication Date
BRPI0818324A2 true BRPI0818324A2 (pt)	2017-05-16
BRPI0818324B1 BRPI0818324B1 (pt)	2019-12-24
BRPI0818324B8 BRPI0818324B8 (pt)	2021-05-25

Family

ID=39167502

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0818324A BRPI0818324B8 (pt)	2007-11-01	2008-10-29	formulação líquida contendo hormônio luteinizante (lh) ou uma variante do mesmo, seu uso, sua forma de apresentação, processo para a sua preparação e composição farmacêutica

Country Status (25)

Country	Link
US (1)	US8664369B2 (pt)
EP (1)	EP2219607B1 (pt)
JP (1)	JP5551601B2 (pt)
KR (1)	KR101513181B1 (pt)
CN (1)	CN101842083B (pt)
AU (1)	AU2008320844B2 (pt)
BR (1)	BRPI0818324B8 (pt)
CA (1)	CA2700662C (pt)
CY (1)	CY1113121T1 (pt)
DK (1)	DK2219607T3 (pt)
EA (1)	EA019432B1 (pt)
EC (1)	ECSP10010224A (pt)
ES (1)	ES2393233T3 (pt)
HR (1)	HRP20120660T1 (pt)
IL (1)	IL205105A (pt)
MX (1)	MX2010004639A (pt)
MY (1)	MY153976A (pt)
NZ (1)	NZ583991A (pt)
PL (1)	PL2219607T3 (pt)
PT (1)	PT2219607E (pt)
RS (1)	RS52566B (pt)
SI (1)	SI2219607T1 (pt)
UA (1)	UA101484C2 (pt)
WO (1)	WO2009056569A1 (pt)
ZA (1)	ZA201001907B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK2229407T3 (en)	2008-01-09	2017-02-27	Sanofi Aventis Deutschland	NEW INSULIN DERIVATIVES WITH EXTREMELY DELAYED TIME / EFFECTS PROFILE
CN103736082A (zh)	2008-10-17	2014-04-23	赛诺菲-安万特德国有限公司	胰岛素和glp-1激动剂的组合
JP2011001273A (ja) *	2009-06-16	2011-01-06	Eci Inc	ｅＭＩＰを有効成分とする水溶性製剤
PH12011502708B1 (en) *	2009-07-06	2017-11-10	Sanofi Aventis Deutschland	Insulin preparations containing methionine
AU2010317995B2 (en)	2009-11-13	2014-04-17	Sanofi-Aventis Deutschland Gmbh	Pharmaceutical composition comprising a GLP-1 agonist, an insulin, and methionine
CN102711804B (zh)	2009-11-13	2015-09-16	赛诺菲-安万特德国有限公司	包含glp-1激动剂和甲硫氨酸的药物组合物
ES2594365T3 (es) *	2010-02-12	2016-12-19	Intas Pharmaceuticals Ltd.	Formulación líquida de hormona estimulante del folículo
PT2611458T (pt)	2010-08-30	2016-12-16	Sanofi Aventis Deutschland	Utilização de ave0010 para o fabrico de um medicamento para o tratamento da diabetes mellitus tipo 2
US9821032B2 (en)	2011-05-13	2017-11-21	Sanofi-Aventis Deutschland Gmbh	Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
CN102293756A (zh) *	2011-08-24	2011-12-28	蚌埠丰原涂山制药有限公司	一种尿促性素冻干粉针剂及其制备方法
ES2550357T3 (es)	2011-08-29	2015-11-06	Sanofi-Aventis Deutschland Gmbh	Combinación farmacéutica para su uso en el control glucémico en pacientes de diabetes de tipo 2
AR087744A1 (es)	2011-09-01	2014-04-16	Sanofi Aventis Deutschland	Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
CN104870469A (zh) *	2012-12-26	2015-08-26	沃克哈特有限公司	药物组合物
TWI641381B (zh)	2013-02-04	2018-11-21	法商賽諾菲公司	胰島素類似物及／或胰島素衍生物之穩定化醫藥調配物
EP2968391A1 (en)	2013-03-13	2016-01-20	Moderna Therapeutics, Inc.	Long-lived polynucleotide molecules
JP6735674B2 (ja)	2014-01-09	2020-08-05	サノフイＳａｎｏｆｉ	インスリンアスパルトの安定化された医薬製剤
KR20160104726A (ko)	2014-01-09	2016-09-05	사노피	인슐린 유사체 및/또는 인슐린 유도체의 안정화된 무글리세롤 약제학적 제형
RU2016132342A (ru)	2014-01-09	2018-02-14	Санофи	Стабилизированные фармацевтические составы на основе инсулиновых аналогов и/или инсулиновых производных
KR102578030B1 (ko)	2014-12-12	2023-09-14	사노피-아벤티스 도이칠란트 게엠베하	인슐린 글라진／릭시세나티드 고정비 제형
TWI748945B (zh)	2015-03-13	2021-12-11	德商賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患治療
TW201705975A (zh)	2015-03-18	2017-02-16	賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患之治療
GB201603280D0 (en) *	2016-02-24	2016-04-13	Ferring Bv	Stable liquid gonadotropin formulation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE64738B1 (en) *	1990-03-20	1995-09-06	Akzo Nv	Stabilized gonadotropin containing preparations
IT1250075B (it) *	1991-12-18	1995-03-30	Serono Cesare Ist Ricerca	Composizioni farmaceutiche contenenti gonadotropine.
US5681302A (en) *	1994-06-14	1997-10-28	Minnesota Mining And Manufacturing Company	Elastic sheet-like composite
PT814841E (pt) *	1995-03-21	2002-03-28	Applied Research Systems	Formulacoes liquidas de hcg
IL122732A0 (en) *	1997-01-15	1998-08-16	Akzo Nobel Nv	Liquid gonadotropin-containing formulation its preparation and a device containing same
JP4719357B2 (ja) *	1998-07-23	2011-07-06	アレストレイディングソシエテアノニム	Ｆｓｈ及びｆｓｈ変異体の製剤、製品及び方法
DE602004019761D1 (de) *	2003-01-08	2009-04-16	Novartis Vaccines & Diagnostic	Stabilisierte wässrige zusammensetzungen mit gewebefaktorinhibitor (tfpi) oder gewebefaktorinhibitor-variante
US7387998B2 (en)	2003-03-28	2008-06-17	New York University	STQ peptides
CA2518903C (en) *	2003-04-02	2013-02-05	Ares Trading S.A.	Liquid pharmaceutical formulations of fsh and lh together with a non-ionic surfactant

2008
- 2008-10-29 ES ES08844750T patent/ES2393233T3/es active Active
- 2008-10-29 JP JP2010531519A patent/JP5551601B2/ja active Active
- 2008-10-29 NZ NZ583991A patent/NZ583991A/en unknown
- 2008-10-29 US US12/681,688 patent/US8664369B2/en active Active
- 2008-10-29 MX MX2010004639A patent/MX2010004639A/es active IP Right Grant
- 2008-10-29 PT PT08844750T patent/PT2219607E/pt unknown
- 2008-10-29 DK DK08844750.3T patent/DK2219607T3/da active
- 2008-10-29 AU AU2008320844A patent/AU2008320844B2/en active Active
- 2008-10-29 RS RS20120484A patent/RS52566B/sr unknown
- 2008-10-29 MY MYPI2010001950A patent/MY153976A/en unknown
- 2008-10-29 UA UAA201006712A patent/UA101484C2/ru unknown
- 2008-10-29 SI SI200830735T patent/SI2219607T1/sl unknown
- 2008-10-29 PL PL08844750T patent/PL2219607T3/pl unknown
- 2008-10-29 KR KR1020107012131A patent/KR101513181B1/ko active Active
- 2008-10-29 HR HRP20120660AT patent/HRP20120660T1/hr unknown
- 2008-10-29 CA CA2700662A patent/CA2700662C/en not_active Expired - Fee Related
- 2008-10-29 WO PCT/EP2008/064679 patent/WO2009056569A1/en not_active Ceased
- 2008-10-29 EA EA201070549A patent/EA019432B1/ru not_active IP Right Cessation
- 2008-10-29 EP EP08844750A patent/EP2219607B1/en active Active
- 2008-10-29 BR BRPI0818324A patent/BRPI0818324B8/pt active IP Right Grant
- 2008-10-29 CN CN2008801145250A patent/CN101842083B/zh active Active
2010
- 2010-03-17 ZA ZA2010/01907A patent/ZA201001907B/en unknown
- 2010-04-15 IL IL205105A patent/IL205105A/en active IP Right Grant
- 2010-05-31 EC EC2010010224A patent/ECSP10010224A/es unknown
2012
- 2012-09-13 CY CY20121100836T patent/CY1113121T1/el unknown

Also Published As

Publication number	Publication date
AU2008320844A1 (en)	2009-05-07
HK1145443A1 (en)	2011-04-21
CA2700662C (en)	2015-10-13
CN101842083B (zh)	2012-11-14
MY153976A (en)	2015-04-30
NZ583991A (en)	2012-02-24
ZA201001907B (en)	2011-05-25
EP2219607B1 (en)	2012-08-15
JP5551601B2 (ja)	2014-07-16
UA101484C2 (en)	2013-04-10
MX2010004639A (es)	2010-08-04
EA019432B1 (ru)	2014-03-31
JP2011502968A (ja)	2011-01-27
IL205105A (en)	2015-04-30
DK2219607T3 (da)	2013-06-17
US20100261649A1 (en)	2010-10-14
BRPI0818324B1 (pt)	2019-12-24
WO2009056569A1 (en)	2009-05-07
KR101513181B1 (ko)	2015-04-21
KR20100088147A (ko)	2010-08-06
IL205105A0 (en)	2010-11-30
EP2219607A1 (en)	2010-08-25
WO2009056569A9 (en)	2010-01-21
SI2219607T1 (sl)	2012-09-28
BRPI0818324B8 (pt)	2021-05-25
CN101842083A (zh)	2010-09-22
ES2393233T3 (es)	2012-12-19
EA201070549A1 (ru)	2010-10-29
PT2219607E (pt)	2012-08-31
PL2219607T3 (pl)	2012-12-31
CY1113121T1 (el)	2016-04-13
ECSP10010224A (es)	2010-07-30
RS52566B (sr)	2013-04-30
AU2008320844B2 (en)	2013-08-29
HRP20120660T1 (hr)	2012-09-30
US8664369B2 (en)	2014-03-04
CA2700662A1 (en)	2009-05-07

Publication	Publication Date	Title
BRPI0818324A2 (pt)	2017-05-16	formulações líquidas de lh
EP3329912C0 (en)	2025-07-23	LIQUID COMPOSITION
BRPI0814252A2 (pt)	2015-04-14	Formulações de anticorpo
BRPI0814003A2 (pt)	2015-02-03	Formulações de anticorpo
EP2212691A4 (en)	2015-09-23	MICROCHIP
BRPI0818380A2 (pt)	2014-10-07	Combinação de herbicida-protetor
BRPI0909644A2 (pt)	2015-09-22	dispositivo de foto-epilação
BRPI0814324A2 (pt)	2015-01-20	Dispositivo
BRPI0822034A2 (pt)	2015-07-21	Dispositivo
DK2114143T3 (da)	2014-07-07	Flydende sulfonylurea-herbicidformuleringer
EP2165942A4 (en)	2012-01-11	Plug structure
BRPI0814188A2 (pt)	2014-10-14	Formulações
DK2789349T3 (da)	2017-11-20	Flydende præparat omfattende pimobendan
EP2192831A4 (en)	2012-12-19	Teat cup lining
EP2183441A4 (en)	2015-07-15	PROCEDURE
BRPI0813976A2 (pt)	2015-01-06	Separador de líquido
BRPI0821224A2 (pt)	2015-06-16	Filtro de líquido
BRPI0811115A2 (pt)	2014-12-23	Compostos de heteroarilamida pirimidona
DE602007000495D1 (de)	2009-03-12	Flüssigkeit-Koinfusionsgerät
EP2189118A4 (en)	2013-10-23	ULTRASOUND DEVICE
DK2196587T3 (da)	2013-07-29	Afløbsindretning
BRPI0906734A2 (pt)	2015-07-07	Dispositivo de virola
BRPI0817518A2 (pt)	2015-03-31	Dispositivo de acoplamento
DE502008001742D1 (de)	2010-12-23	Kabelbearbeitungseinrichtung
BRPI0809653A2 (pt)	2014-10-07	Formulações líquidas de manoproteína

Legal Events

Date	Code	Title	Description
2018-03-06	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2019-07-02	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]	Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI
2019-07-16	B06T	Formal requirements before examination [chapter 6.20 patent gazette]
2019-11-12	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2019-12-24	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 24/12/2019, OBSERVADAS AS CONDICOES LEGAIS.
2021-05-25	B16C	Correction of notification of the grant [chapter 16.3 patent gazette]	Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 29/10/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF