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BRPI0818039A2 - Método para produzir uma célula capaz de produção de alto rendimento de heteroproteínas. - Google Patents

Método para produzir uma célula capaz de produção de alto rendimento de heteroproteínas.

Info

Publication number
BRPI0818039A2
BRPI0818039A2 BRPI0818039-3A2A BRPI0818039A BRPI0818039A2 BR PI0818039 A2 BRPI0818039 A2 BR PI0818039A2 BR PI0818039 A BRPI0818039 A BR PI0818039A BR PI0818039 A2 BRPI0818039 A2 BR PI0818039A2
Authority
BR
Brazil
Prior art keywords
hyperoprotein
income
producing
production cell
cell
Prior art date
Application number
BRPI0818039-3A2A
Other languages
English (en)
Inventor
Hisahiro Tabuchi
Tomoya Sugiyama
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of BRPI0818039A2 publication Critical patent/BRPI0818039A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C12N2500/33—Amino acids other than alpha-amino carboxylic acids, e.g. beta-amino acids, taurine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/06—Anti-neoplasic drugs, anti-retroviral drugs, e.g. azacytidine, cyclophosphamide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BRPI0818039-3A2A 2007-10-15 2008-10-14 Método para produzir uma célula capaz de produção de alto rendimento de heteroproteínas. BRPI0818039A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007267384 2007-10-15
PCT/JP2008/068589 WO2009051109A1 (ja) 2007-10-15 2008-10-14 異種タンパク質を高生産する細胞の作製方法

Publications (1)

Publication Number Publication Date
BRPI0818039A2 true BRPI0818039A2 (pt) 2014-10-14

Family

ID=40567373

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0818039-3A2A BRPI0818039A2 (pt) 2007-10-15 2008-10-14 Método para produzir uma célula capaz de produção de alto rendimento de heteroproteínas.

Country Status (6)

Country Link
US (1) US9802993B2 (pt)
EP (1) EP2194126B1 (pt)
JP (1) JP5337043B2 (pt)
BR (1) BRPI0818039A2 (pt)
RU (1) RU2486245C2 (pt)
WO (1) WO2009051109A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007119774A1 (ja) 2006-04-13 2007-10-25 Chugai Seiyaku Kabushiki Kaisha タウリントランスポーター遺伝子
US20100233759A1 (en) 2007-03-15 2010-09-16 Chugai Seiyaku Kabushiki Kaisha Method for production of polypeptide
EP2186905B1 (en) 2007-08-07 2016-07-13 Chugai Seiyaku Kabushiki Kaisha Method of producing heterogeneous protein
WO2009051109A1 (ja) 2007-10-15 2009-04-23 Chugai Seiyaku Kabushiki Kaisha 異種タンパク質を高生産する細胞の作製方法
JP5337044B2 (ja) 2007-10-24 2013-11-06 中外製薬株式会社 異種タンパク質製造のための細胞及びそれを用いた製造方法
JP5715050B2 (ja) 2009-04-22 2015-05-07 中外製薬株式会社 異種タンパク質を高生産する細胞の作製方法
TWI647309B (zh) 2011-04-01 2019-01-11 Chugai Seiyaku Kabushiki Kaisha 重組多肽之製造方法
CN112522353A (zh) * 2012-10-10 2021-03-19 中外制药株式会社 经修饰的宿主细胞的建立方法
KR102467730B1 (ko) * 2014-08-11 2022-11-15 에프. 호프만-라 로슈 아게 진핵생물 세포의 비생산률 증가를 위한 방법
GB2596803A (en) * 2020-07-06 2022-01-12 Petmedix Ltd Expression vector production & high-throughput cell screening

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JP3630453B2 (ja) 1994-09-30 2005-03-16 中外製薬株式会社 Ｉｌ−６レセプター抗体を有効成分とする未熟型骨髄腫細胞治療剤
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US20100233759A1 (en) * 2007-03-15 2010-09-16 Chugai Seiyaku Kabushiki Kaisha Method for production of polypeptide
EP2186905B1 (en) 2007-08-07 2016-07-13 Chugai Seiyaku Kabushiki Kaisha Method of producing heterogeneous protein
WO2009051109A1 (ja) 2007-10-15 2009-04-23 Chugai Seiyaku Kabushiki Kaisha 異種タンパク質を高生産する細胞の作製方法
JP5337044B2 (ja) 2007-10-24 2013-11-06 中外製薬株式会社 異種タンパク質製造のための細胞及びそれを用いた製造方法
JP5715050B2 (ja) * 2009-04-22 2015-05-07 中外製薬株式会社 異種タンパク質を高生産する細胞の作製方法

Also Published As

Publication number Publication date
RU2486245C2 (ru) 2013-06-27
EP2194126A4 (en) 2011-01-19
EP2194126B1 (en) 2014-01-15
JPWO2009051109A1 (ja) 2011-03-03
WO2009051109A1 (ja) 2009-04-23
US20110003334A1 (en) 2011-01-06
EP2194126A1 (en) 2010-06-09
JP5337043B2 (ja) 2013-11-06
RU2010119558A (ru) 2011-11-27
US9802993B2 (en) 2017-10-31

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Legal Events

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL

B350 Update of information on the portal [chapter 15.35 patent gazette]