BRPI0816230A2 - Mediação citotóxica de evidenciando expressão de superfície de cd9 - Google Patents

Mediação citotóxica de evidenciando expressão de superfície de cd9

Info

Publication number: BRPI0816230A2
Authority: BR; Brazil
Prior art keywords: evidencing; surface expression; mediation; cytotoxic; cytotoxic mediation
Prior art date: 2007-08-17

Application number

BRPI0816230-1A

Other languages

English (en)

Inventor

Lisa M Cechetto

Alison L Ferry

Helen P Findlay

Susan E Hahn

David S F Young

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-17

Filing date

2008-08-13

Publication date

2015-06-16

2008-08-13 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2015-06-16 Publication of BRPI0816230A2 publication Critical patent/BRPI0816230A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6813—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
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- A61K47/6855—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cell
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3015—Breast
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/303—Liver or Pancreas
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Cell Biology (AREA)
Organic Chemistry (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Physics & Mathematics (AREA)
Optics & Photonics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

BRPI0816230-1A 2007-08-17 2008-08-13 Mediação citotóxica de evidenciando expressão de superfície de cd9 BRPI0816230A2 (pt)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US96516507P	2007-08-17	2007-08-17
US2658408P	2008-02-06	2008-02-06
US12401908P	2008-04-11	2008-04-11
PCT/CA2008/001452 WO2009023955A1 (en)	2007-08-17	2008-08-13	Cytotoxicity mediation of cells evidencing surface expression of cd9

Publications (1)

Publication Number	Publication Date
BRPI0816230A2 true BRPI0816230A2 (pt)	2015-06-16

Family

ID=40377777

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0816230-1A BRPI0816230A2 (pt)	2007-08-17	2008-08-13	Mediação citotóxica de evidenciando expressão de superfície de cd9

Country Status (12)

Country	Link
US (1)	US20090068182A1 (pt)
EP (1)	EP2190880A1 (pt)
KR (1)	KR20100043077A (pt)
CN (1)	CN101784566A (pt)
AU (1)	AU2008288639A1 (pt)
BR (1)	BRPI0816230A2 (pt)
CA (1)	CA2696027A1 (pt)
CO (1)	CO6311010A2 (pt)
CR (1)	CR11238A (pt)
EC (1)	ECSP109970A (pt)
MX (1)	MX2010001637A (pt)
WO (1)	WO2009023955A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2011004899A1 (en) *	2009-07-06	2011-01-13	Takeda Pharmaceutical Company Limited	Cancerous disease modifying antibodies
FI2691417T4 (fi) *	2011-03-29	2025-01-14	Roche Glycart Ag	Vasta-aineen Fc-variantteja
RS62509B1 (sr)	2012-07-13	2021-11-30	Roche Glycart Ag	Bispecifična anti-vegf/anti-ang-2 antitela i njihova upotreba u lečenju očnih vaskularnih bolesti
EA201891299A1 (ru)	2016-01-08	2019-01-31	Аимм Терапьютикс Б.В.	Терапевтические антитела к cd9
MA54052A (fr)	2018-10-29	2022-02-09	Hoffmann La Roche	Formulation d'anticorps
WO2021160267A1 (en) *	2020-02-13	2021-08-19	UCB Biopharma SRL	Bispecific antibodies against cd9 and cd7
WO2021160265A1 (en) *	2020-02-13	2021-08-19	UCB Biopharma SRL	Bispecific antibodies against cd9 and cd137
US20230151109A1 (en) *	2020-02-13	2023-05-18	UCB Biopharma SRL	Bispecific antibodies against cd9

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6180357B1 (en) *	1999-10-08	2001-01-30	Arius Research, Inc.	Individualized patient-specific anti-cancer antibodies

2008
- 2008-02-02 MX MX2010001637A patent/MX2010001637A/es unknown
- 2008-08-13 US US12/228,682 patent/US20090068182A1/en not_active Abandoned
- 2008-08-13 CN CN200880103585A patent/CN101784566A/zh active Pending
- 2008-08-13 AU AU2008288639A patent/AU2008288639A1/en not_active Abandoned
- 2008-08-13 EP EP08783362A patent/EP2190880A1/en not_active Ceased
- 2008-08-13 WO PCT/CA2008/001452 patent/WO2009023955A1/en not_active Ceased
- 2008-08-13 BR BRPI0816230-1A patent/BRPI0816230A2/pt not_active IP Right Cessation
- 2008-08-13 CA CA2696027A patent/CA2696027A1/en not_active Withdrawn
- 2008-08-13 KR KR1020107003495A patent/KR20100043077A/ko not_active Withdrawn
2010
- 2010-01-27 CR CR11238A patent/CR11238A/es not_active Application Discontinuation
- 2010-02-17 EC EC2010009970A patent/ECSP109970A/es unknown
- 2010-03-08 CO CO10027142A patent/CO6311010A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
US20090068182A1 (en)	2009-03-12
WO2009023955A8 (en)	2010-03-04
CN101784566A (zh)	2010-07-21
EP2190880A1 (en)	2010-06-02
AU2008288639A1 (en)	2009-02-26
CO6311010A2 (es)	2011-08-22
CR11238A (es)	2010-04-21
WO2009023955A1 (en)	2009-02-26
KR20100043077A (ko)	2010-04-27
CA2696027A1 (en)	2009-02-26
ECSP109970A (es)	2010-03-31
MX2010001637A (es)	2010-03-15

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DE112007001601A5 (de)	2009-07-23	Keramikdüse
ZA201000994B (en)	2010-10-27	Cytotoxicity mediation of cells evidencing surface expression of CD9
FR2935040B1 (fr)	2012-10-19	Chambre d'oxy-combustion
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