BRPI0808577A2 - multienzima, polinuleotídeos isolados, construção recombinante, célula hospedeira, yarrowia sp. transformada, método de transformaçao celular, método para a produção de uma planta transformada, de leveduras, planta, sementes, óleos, produtos alimentícios ou rações, bebidas, moléculas isoladas de ácido nucléico, método de produção de uma multienzima, método para alterar o perfil de ácidos graxos, progênie, células hospedeiras microbianas recombinantes, métodos para conversão de ácido linoléico para ácido dihomo gamma-linolênico, ácido a-linolênico para ácido eicosatrienóico, ácido eicosapentaenóico para ácido docosahexaenóico, ácido araquidônico para ácido docosapentaenóico, método para a identificação de um polipeptídeo - Google Patents
multienzima, polinuleotídeos isolados, construção recombinante, célula hospedeira, yarrowia sp. transformada, método de transformaçao celular, método para a produção de uma planta transformada, de leveduras, planta, sementes, óleos, produtos alimentícios ou rações, bebidas, moléculas isoladas de ácido nucléico, método de produção de uma multienzima, método para alterar o perfil de ácidos graxos, progênie, células hospedeiras microbianas recombinantes, métodos para conversão de ácido linoléico para ácido dihomo gamma-linolênico, ácido a-linolênico para ácido eicosatrienóico, ácido eicosapentaenóico para ácido docosahexaenóico, ácido araquidônico para ácido docosapentaenóico, método para a identificação de um polipeptídeoInfo
- Publication number
- BRPI0808577A2 BRPI0808577A2 BRPI0808577A BRPI0808577A BRPI0808577A2 BR PI0808577 A2 BRPI0808577 A2 BR PI0808577A2 BR PI0808577 A BRPI0808577 A BR PI0808577A BR PI0808577 A BRPI0808577 A BR PI0808577A BR PI0808577 A2 BRPI0808577 A2 BR PI0808577A2
- Authority
- BR
- Brazil
- Prior art keywords
- acid
- plant
- isolated
- linolenic
- recombinant
- Prior art date
Links
- 238000000034 method Methods 0.000 title 3
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 title 2
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 title 2
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 2
- BBWMTEYXFFWPIF-CJBMEHDJSA-N (2e,4e,6e)-icosa-2,4,6-trienoic acid Chemical compound CCCCCCCCCCCCC\C=C\C=C\C=C\C(O)=O BBWMTEYXFFWPIF-CJBMEHDJSA-N 0.000 title 1
- YUFFSWGQGVEMMI-JLNKQSITSA-N (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(O)=O YUFFSWGQGVEMMI-JLNKQSITSA-N 0.000 title 1
- HOBAELRKJCKHQD-UHFFFAOYSA-N (8Z,11Z,14Z)-8,11,14-eicosatrienoic acid Natural products CCCCCC=CCC=CCC=CCCCCCCC(O)=O HOBAELRKJCKHQD-UHFFFAOYSA-N 0.000 title 1
- 235000021298 Dihomo-γ-linolenic acid Nutrition 0.000 title 1
- 235000021294 Docosapentaenoic acid Nutrition 0.000 title 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 title 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 title 1
- 241000490645 Yarrowia sp. Species 0.000 title 1
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 title 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 title 1
- 235000021342 arachidonic acid Nutrition 0.000 title 1
- 229940114079 arachidonic acid Drugs 0.000 title 1
- 235000013361 beverage Nutrition 0.000 title 1
- 230000010307 cell transformation Effects 0.000 title 1
- 235000014113 dietary fatty acids Nutrition 0.000 title 1
- HOBAELRKJCKHQD-QNEBEIHSSA-N dihomo-γ-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O HOBAELRKJCKHQD-QNEBEIHSSA-N 0.000 title 1
- 235000020669 docosahexaenoic acid Nutrition 0.000 title 1
- 229940090949 docosahexaenoic acid Drugs 0.000 title 1
- 235000020673 eicosapentaenoic acid Nutrition 0.000 title 1
- 229960005135 eicosapentaenoic acid Drugs 0.000 title 1
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 title 1
- 229930195729 fatty acid Natural products 0.000 title 1
- 239000000194 fatty acid Substances 0.000 title 1
- 150000004665 fatty acids Chemical class 0.000 title 1
- 235000013305 food Nutrition 0.000 title 1
- 235000020778 linoleic acid Nutrition 0.000 title 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 title 1
- 229960004488 linolenic acid Drugs 0.000 title 1
- 230000000813 microbial effect Effects 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 239000003921 oil Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000011426 transformation method Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6434—Docosahexenoic acids [DHA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/19—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
- C12Y114/19001—Stearoyl-CoA 9-desaturase (1.14.19.1), i.e. DELTA9-desaturase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Fodder In General (AREA)
- Edible Oils And Fats (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90979007P | 2007-04-03 | 2007-04-03 | |
| US2789808P | 2008-02-12 | 2008-02-12 | |
| PCT/US2008/004377 WO2008124048A2 (en) | 2007-04-03 | 2008-04-03 | Multizymes and their use in making polyunsaturated fatty acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0808577A2 true BRPI0808577A2 (pt) | 2019-09-24 |
Family
ID=39650608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0808577A BRPI0808577A2 (pt) | 2007-04-03 | 2008-04-03 | multienzima, polinuleotídeos isolados, construção recombinante, célula hospedeira, yarrowia sp. transformada, método de transformaçao celular, método para a produção de uma planta transformada, de leveduras, planta, sementes, óleos, produtos alimentícios ou rações, bebidas, moléculas isoladas de ácido nucléico, método de produção de uma multienzima, método para alterar o perfil de ácidos graxos, progênie, células hospedeiras microbianas recombinantes, métodos para conversão de ácido linoléico para ácido dihomo gamma-linolênico, ácido a-linolênico para ácido eicosatrienóico, ácido eicosapentaenóico para ácido docosahexaenóico, ácido araquidônico para ácido docosapentaenóico, método para a identificação de um polipeptídeo |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8828690B2 (pt) |
| EP (1) | EP2129777B1 (pt) |
| JP (1) | JP2010523113A (pt) |
| CN (2) | CN101765658B (pt) |
| BR (1) | BRPI0808577A2 (pt) |
| CA (1) | CA2679988A1 (pt) |
| DK (1) | DK2129777T3 (pt) |
| ES (1) | ES2559312T3 (pt) |
| HU (1) | HUE028692T2 (pt) |
| MX (1) | MX2009010574A (pt) |
| RS (1) | RS20090413A (pt) |
| RU (2) | RU2517608C2 (pt) |
| UA (1) | UA103595C2 (pt) |
| WO (1) | WO2008124048A2 (pt) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7807849B2 (en) | 2004-04-22 | 2010-10-05 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| CA3023314C (en) | 2004-04-22 | 2019-12-10 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| AU2007291937B2 (en) | 2006-08-29 | 2014-05-15 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of fatty acids |
| US7794701B2 (en) * | 2007-04-16 | 2010-09-14 | E.I. Du Pont De Nemours And Company | Δ-9 elongases and their use in making polyunsaturated fatty acids |
| US8957280B2 (en) * | 2007-05-03 | 2015-02-17 | E. I. Du Pont De Nemours And Company | Delta-5 desaturases and their use in making polyunsaturated fatty acids |
| AU2008281760B2 (en) * | 2007-07-31 | 2014-07-17 | Basf Plant Science Gmbh | Elongases and methods for producing polyunsaturated fatty acids in transgenic organisms |
| US8323935B2 (en) * | 2007-10-03 | 2012-12-04 | E I Du Pont De Nemours And Company | Optimized strains of Yarrowia lipolytica for high eicosapentaenoic acid production |
| WO2009124225A1 (en) * | 2008-04-03 | 2009-10-08 | E. I. Du Pont De Nemours And Company | Multizymes |
| US8168858B2 (en) | 2008-06-20 | 2012-05-01 | E. I. Du Pont De Nemours And Company | Delta-9 fatty acid elongase genes and their use in making polyunsaturated fatty acids |
| NO2358882T3 (pt) | 2008-11-18 | 2017-12-23 | ||
| CA2744716C (en) | 2008-12-18 | 2017-05-23 | E.I. Du Pont De Nemours And Company | Reducing byproduction of malonates in a fermentation process |
| WO2010147907A1 (en) | 2009-06-16 | 2010-12-23 | E. I. Du Pont De Nemours And Company | High eicosapentaenoic acid oils from improved optimized strains of yarrowia lipolytica |
| CN102459627B (zh) | 2009-06-16 | 2015-07-29 | 纳幕尔杜邦公司 | 通过酰基-辅酶A溶血磷脂酰基转移酶的表达对长链ω-3和ω-6多不饱和脂肪酸的生物合成的改善 |
| EP2475679B1 (en) * | 2009-06-16 | 2016-02-10 | E. I. du Pont de Nemours and Company | Improved optimized strains of yarrowia lipolytica for high eicosapentaenoic acid production |
| US8637298B2 (en) * | 2009-06-16 | 2014-01-28 | E I Du Pont De Nemours And Company | Optimized strains of yarrowia lipolytica for high eicosapentaenoic acid production |
| BRPI1008189A2 (pt) | 2009-06-30 | 2015-08-25 | Du Pont | Planta transgenica semente transgenica obtida a partir da planta transgencia semente transgencia metodo de produção de uma planta transgenica metodo de produção de sementes transgenicas metodo de produto e ou subproduto da semente transgenica e semente transgenica obtida pelo metodo |
| US8188335B2 (en) | 2009-07-17 | 2012-05-29 | Abbott Laboratories | Δ9-elongase for production of polyunsaturated fatty acid-enriched oils |
| EP2454278B1 (en) | 2009-07-17 | 2019-06-19 | BASF Plant Science Company GmbH | Novel fatty acid desaturases and elongases and uses thereof |
| AR078829A1 (es) | 2009-10-30 | 2011-12-07 | Du Pont | Plantas y semillas con niveles alterados de compuesto de almacenamiento, construcciones relacionadas y metodos relacionados con genes que codifican proteinas similares a las aldolasas bacterianas de la clase ii del acido 2,4- dihidroxi-hept-2-eno-1,7-dioico |
| ES2750241T3 (es) | 2009-11-03 | 2020-03-25 | Dsm Ip Assets Bv | Aceite vegetal que comprende un ácido graso poliinsaturado que tiene al menos 20 átomos de carbono |
| KR101889561B1 (ko) | 2009-11-03 | 2018-08-17 | 디에스엠 아이피 어셋츠 비.브이. | 세포 및 20개 이상의 탄소 원자를 가진 다가불포화 지방산을 포함하는 조성물 |
| BR112012012374A2 (pt) | 2009-11-23 | 2015-09-15 | Du Pont | semente de planta com maior teor de óleo, planta, método para aumentar ainda mais o teor de óleo em uma semente de planta de alto teor de óleo, método par avaliar o teor de óleo aumentado em uma semente de planta, polinucleotídeo isolado polipeptídeo isolado |
| EP2516638A1 (en) | 2009-12-24 | 2012-10-31 | E.I. Du Pont De Nemours And Company | Plant membrane bound o-acyl transferase (mboat) family protein sequences and their uses for altering fatty acid compositions |
| WO2011087981A2 (en) | 2010-01-15 | 2011-07-21 | E. I. Du Pont De Nemours And Company | Clinical benefits of eicosapentaenoic acid in humans |
| EP3312271A1 (en) * | 2010-03-02 | 2018-04-25 | Massachusetts Institute Of Technology | Microbial engineering for the production of fatty acids and fatty acid derivatives |
| BR112012022045A8 (pt) | 2010-03-03 | 2018-06-19 | Du Pont | ''planta transgênica,semente transgênica,método para produzir uma planta transgênica,método para produzir sementes transgênicas,produto e/ou subproduto,polinucleotídeo isolado e planta ou semente''. |
| AU2011242843A1 (en) | 2010-04-22 | 2012-09-27 | E. I. Du Pont De Nemours And Company | Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass |
| AU2011271497A1 (en) | 2010-07-01 | 2013-01-10 | E. I. Du Pont De Nemours And Company | Plant seeds with altered storage compound levels, related constructs and methods involving genes encoding PAE and PAE-like polypeptides |
| AU2011293180B2 (en) * | 2010-08-26 | 2017-03-02 | E. I. Du Pont De Nemours And Company | Recombinant microbial host cells for high eicosapentaenoic acid production |
| BR112013004355A2 (pt) | 2010-08-26 | 2021-05-04 | E.I. Du Pont De Nemours And Company | polipeptídeo mutante possuindo atividade delta-5 dessaturase, molécula de ácido nucleico isolada e célula transformada. |
| DK2609201T3 (en) * | 2010-08-26 | 2016-06-06 | Du Pont | Mutant DELTA-9 elongases AND USE THEREOF FOR THE PRODUCTION OF polyunsaturated fatty acids |
| CN103443266A (zh) | 2010-12-30 | 2013-12-11 | 纳幕尔杜邦公司 | 在解脂耶氏酵母中使用啤酒糖酵母suc2基因以利用蔗糖 |
| US20130040340A1 (en) | 2011-02-07 | 2013-02-14 | E. I. Du Pont De Nemours And Company | Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms |
| US8999663B2 (en) | 2011-02-11 | 2015-04-07 | E L Du Pont De Nemours And Company | Method for obtaining a lipid-containing composition from microbial biomass |
| US20120247066A1 (en) | 2011-04-01 | 2012-10-04 | Ice House America, Llc | Ice bagging apparatus and methods |
| CA2833400A1 (en) | 2011-05-26 | 2012-11-29 | E.I. Dupont De Nemours And Company | Expression of caleosin in recombinant oleaginous microorganisms to increase oil content therein |
| US9294428B2 (en) * | 2012-01-18 | 2016-03-22 | Kinectus, Llc | Systems and methods for establishing communications between mobile device users |
| ES2635115T3 (es) * | 2012-01-23 | 2017-10-02 | E. I. Du Pont De Nemours And Company | Regulación por disminución de expresión génica utilizando micro ARN artificiales para silenciar genes biosintéticos de ácidos grasos |
| BR112014031362A8 (pt) | 2012-06-15 | 2022-06-28 | Commw Scient Ind Res Org | Lipídeo de planta extraído, processo para produzir lipídeo de planta extraído, célula hospedeira, método de produzir semente, farinha de semente, método para produzir um produto alimentício, uso e processo para produzir ésteres etílicos de ácidos graxos poli-insaturados |
| EP2861728B1 (en) | 2012-06-19 | 2017-12-27 | E. I. du Pont de Nemours and Company | Improved production of polyunsaturated fatty acids by coexpression of acyl-coa: lysophosphatidylcholine acyltransferases and phospholipid: diacylglycerol acyltransferases |
| EP2935591B1 (en) | 2012-12-21 | 2017-07-05 | E. I. du Pont de Nemours and Company | Down-regulation of a polynucleotide encoding a sou2 sorbitol utilization protein to modify lipid production in microbial cells |
| US9725399B2 (en) | 2013-12-18 | 2017-08-08 | Commonwealth Scientific And Industrial Research Organisation | Lipid comprising long chain polyunsaturated fatty acids |
| SG11201610596PA (en) * | 2014-06-27 | 2017-01-27 | Commw Scient Ind Res Org | Lipid comprising docosapentaenoic acid |
| WO2016073433A1 (en) | 2014-11-06 | 2016-05-12 | E. I. Du Pont De Nemours And Company | Peptide-mediated delivery of rna-guided endonuclease into cells |
| US10393225B2 (en) * | 2015-01-05 | 2019-08-27 | Goodrich Corporation | Integrated multi-function propulsion belt for air cushion supported aircraft cargo loading robot |
| CN110087481A (zh) | 2016-12-15 | 2019-08-02 | 帝斯曼知识产权资产管理有限公司 | 包含硅酸盐和含具有至少20个碳原子的多不饱和脂肪酸(lc-pufa)的微生物细胞和/或植物细胞的共混物制剂 |
| US11519009B2 (en) | 2017-01-09 | 2022-12-06 | University Of Massachusetts | Complexes for gene deletion and editing |
| CN115820586B (zh) * | 2022-09-06 | 2025-07-22 | 中国农业科学院油料作物研究所 | 一种溶血磷脂酰胆碱酰基转移酶、核酸分子及其应用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0616644B1 (en) | 1991-12-04 | 2003-07-02 | E.I. Du Pont De Nemours And Company | Fatty acid desaturase genes from plants |
| US5547868A (en) * | 1993-06-09 | 1996-08-20 | Regents Of The University Of California | Cholesterol disposal fusion enzymes |
| US6075183A (en) | 1997-04-11 | 2000-06-13 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants |
| US5968809A (en) | 1997-04-11 | 1999-10-19 | Abbot Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| US6677145B2 (en) | 1998-09-02 | 2004-01-13 | Abbott Laboratories | Elongase genes and uses thereof |
| US6403349B1 (en) | 1998-09-02 | 2002-06-11 | Abbott Laboratories | Elongase gene and uses thereof |
| NZ512656A (en) | 1998-12-07 | 2003-09-26 | Univ Washington | Desaturases and methods of using them for synthesis of polyunsaturated fatty acids |
| US6825017B1 (en) | 1998-12-07 | 2004-11-30 | Washington State University Research Foundation | Desaturases and methods of using them for synthesis of polyunsaturated fatty acids |
| RU2336307C2 (ru) * | 2000-01-19 | 2008-10-20 | Мартек Биосайнсис Корпорейшн | Способ получения липидов (варианты) и липиды, полученные этим способом |
| AU2002218447C9 (en) | 2000-09-28 | 2008-04-17 | Bioriginal Food & Science Corporation | Fad4, Fad5, Fad5-2, and Fad6, fatty acid desaturase family members and uses thereof |
| DE10102338A1 (de) * | 2001-01-19 | 2002-07-25 | Basf Plant Science Gmbh | Verfahren zur Expression von Biosynthesegenen in pflanzlichen Samen unter Verwendung von neuen multiplen Expressionskonstrukten |
| DE10102337A1 (de) * | 2001-01-19 | 2002-07-25 | Basf Plant Science Gmbh | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte |
| BR0205508A (pt) | 2001-01-25 | 2005-05-03 | Abbott Lab | Genes para dessaturase e usos dos mesmos |
| GB0107510D0 (en) | 2001-03-26 | 2001-05-16 | Univ Bristol | New elongase gene and a process for the production of -9-polyunsaturated fatty acids |
| US7045683B2 (en) | 2001-05-04 | 2006-05-16 | Abbott Laboratories | Δ4-desaturase genes and uses thereof |
| CA2510462A1 (en) * | 2002-12-19 | 2004-07-08 | University Of Bristol | Method for producing polyunsaturated fatty acids in a transgenic plant or microorganism comprising an introduced delta-9-elongase and a delta-8-desaturase |
| US20040172682A1 (en) | 2003-02-12 | 2004-09-02 | Kinney Anthony J. | Production of very long chain polyunsaturated fatty acids in oilseed plants |
| WO2004090123A2 (de) * | 2003-04-08 | 2004-10-21 | Basf Plant Science Gmbh | Δ-4-desaturasen aus euglena gracilis, exprimierende pflanzen und pufa enthaltende öle |
| US7125672B2 (en) | 2003-05-07 | 2006-10-24 | E. I. Du Pont De Nemours And Company | Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts |
| US7214491B2 (en) | 2003-05-07 | 2007-05-08 | E. I. Du Pont De Nemours And Company | Δ-12 desaturase gene suitable for altering levels of polyunsaturated fatty acids in oleaginous yeasts |
| US7238482B2 (en) | 2003-05-07 | 2007-07-03 | E. I. Du Pont De Nemours And Company | Production of polyunsaturated fatty acids in oleaginous yeasts |
| ES2590077T3 (es) * | 2003-08-01 | 2016-11-18 | Basf Plant Science Gmbh | Procedimiento para la producción de ácidos grasos poliinsaturados en organismos transgénicos |
| US7504259B2 (en) | 2003-11-12 | 2009-03-17 | E. I. Du Pont De Nemours And Company | Δ12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast |
| US20050132441A1 (en) | 2003-11-12 | 2005-06-16 | Damude Howard G. | Delta15 desaturases suitable for altering levels of polyunsaturated fatty acids in oilseed plants and oleaginous yeast |
| EP3543324B1 (de) * | 2004-02-27 | 2022-11-30 | BASF Plant Science GmbH | Verfahren zur herstellung mehrfach ungesättigten fettsäuren in transgenen pflanzen |
| US7807849B2 (en) * | 2004-04-22 | 2010-10-05 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| CA3023314C (en) | 2004-04-22 | 2019-12-10 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| BRPI0512481A (pt) | 2004-06-25 | 2008-03-11 | Du Pont | polinucleotìdeo isolado, polipeptìdeo, construção recombinante, célula, yarrowia sp.transformada, métodos para transformar uma célula, produzir uma planta transformada, produzir levedura, produzir ácidos graxos poliinsaturados e produzir pelo menos um ácido graxo poliinsaturados, sementes, óleos, plantas de sementes oleaginosa e alimentos ou rações |
| US7189559B2 (en) * | 2004-11-04 | 2007-03-13 | E. I. Du Pont De Nemours And Company | Mortierella alpina lysophosphatidic acid acyltransferase homolog for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms |
| US7470532B2 (en) | 2005-10-19 | 2008-12-30 | E.I. Du Pont De Nemours And Company | Mortierella alpina C16/18 fatty acid elongase |
| BRPI0620552A2 (pt) | 2005-11-23 | 2011-11-22 | Du Pont | polinucleotìdeo isolado, polipeptìdeo delta-9 elongase, construção recombinante, célula vegetal, método para transformar uma célula, método para produção de uma planta transgênica, sementes transgênicas, método para fabricar ácidos graxos poliinsaturados de cadeia longa, óleos, método para produzir pelo menos um ácido graxo poliinsaturado, plantas de semente oleaginosa, sementes, alimentos, fragmento de ácido nucléico isolado e progênies de plantas |
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| HUE028692T2 (en) | 2016-12-28 |
| US20080254191A1 (en) | 2008-10-16 |
| DK2129777T3 (en) | 2016-01-25 |
| RU2517608C2 (ru) | 2014-05-27 |
| CN101765658B (zh) | 2013-11-20 |
| WO2008124048A2 (en) | 2008-10-16 |
| RS20090413A (sr) | 2010-06-30 |
| WO2008124048A8 (en) | 2011-11-03 |
| MX2009010574A (es) | 2009-10-22 |
| CN101765658A (zh) | 2010-06-30 |
| CA2679988A1 (en) | 2008-10-16 |
| US8828690B2 (en) | 2014-09-09 |
| WO2008124048A3 (en) | 2009-02-05 |
| EP2129777A2 (en) | 2009-12-09 |
| US20150031096A1 (en) | 2015-01-29 |
| RU2009140397A (ru) | 2011-05-10 |
| ES2559312T3 (es) | 2016-02-11 |
| JP2010523113A (ja) | 2010-07-15 |
| UA103595C2 (uk) | 2013-11-11 |
| CN104152423A (zh) | 2014-11-19 |
| EP2129777B1 (en) | 2015-10-28 |
| RU2014102130A (ru) | 2015-08-27 |
| AU2008236723A1 (en) | 2008-10-16 |
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