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MX2009010574A - Multienzimas y su uso en la fabricacion de acidos grasos poliinsaturados. - Google Patents

Multienzimas y su uso en la fabricacion de acidos grasos poliinsaturados.

Info

Publication number
MX2009010574A
MX2009010574A MX2009010574A MX2009010574A MX2009010574A MX 2009010574 A MX2009010574 A MX 2009010574A MX 2009010574 A MX2009010574 A MX 2009010574A MX 2009010574 A MX2009010574 A MX 2009010574A MX 2009010574 A MX2009010574 A MX 2009010574A
Authority
MX
Mexico
Prior art keywords
multizymes
fatty acids
polyunsaturated fatty
making polyunsaturated
making
Prior art date
Application number
MX2009010574A
Other languages
English (en)
Inventor
Anthony J Kinney
Kevin G Ripp
Quinn Qun Zhu
Howard G Damude
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of MX2009010574A publication Critical patent/MX2009010574A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
    • C12Y114/19001—Stearoyl-CoA 9-desaturase (1.14.19.1), i.e. DELTA9-desaturase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Edible Oils And Fats (AREA)
  • Fodder In General (AREA)

Abstract

La presente invención describe fragmentos de acido nucleico y construcciones recombinantes que comprenden los fragmentos que codifican multienzimas (es decir, polipéptidos simples con al menos dos actividades enzimáticas independientes y divisibles) junto con un método de elaboración de ácidos grasos poliinsaturados de cadena larga (PUFA) usando tres multienzimas en plantas y levadura oleaginosa.
MX2009010574A 2007-04-03 2008-04-03 Multienzimas y su uso en la fabricacion de acidos grasos poliinsaturados. MX2009010574A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90979007P 2007-04-03 2007-04-03
US2789808P 2008-02-12 2008-02-12
PCT/US2008/004377 WO2008124048A2 (en) 2007-04-03 2008-04-03 Multizymes and their use in making polyunsaturated fatty acids

Publications (1)

Publication Number Publication Date
MX2009010574A true MX2009010574A (es) 2009-10-22

Family

ID=39650608

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009010574A MX2009010574A (es) 2007-04-03 2008-04-03 Multienzimas y su uso en la fabricacion de acidos grasos poliinsaturados.

Country Status (14)

Country Link
US (2) US8828690B2 (es)
EP (1) EP2129777B1 (es)
JP (1) JP2010523113A (es)
CN (2) CN104152423A (es)
BR (1) BRPI0808577A2 (es)
CA (1) CA2679988A1 (es)
DK (1) DK2129777T3 (es)
ES (1) ES2559312T3 (es)
HU (1) HUE028692T2 (es)
MX (1) MX2009010574A (es)
RS (1) RS20090413A (es)
RU (2) RU2517608C2 (es)
UA (1) UA103595C2 (es)
WO (1) WO2008124048A2 (es)

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AU2010317140B2 (en) 2009-11-03 2016-04-21 Dsm Ip Assets B.V. Vegatable oil comprising a polyunsaturaded fatty acid having at least 20 carbon atoms
KR101889561B1 (ko) 2009-11-03 2018-08-17 디에스엠 아이피 어셋츠 비.브이. 세포 및 20개 이상의 탄소 원자를 가진 다가불포화 지방산을 포함하는 조성물
BR112012012374A2 (pt) 2009-11-23 2015-09-15 Du Pont semente de planta com maior teor de óleo, planta, método para aumentar ainda mais o teor de óleo em uma semente de planta de alto teor de óleo, método par avaliar o teor de óleo aumentado em uma semente de planta, polinucleotídeo isolado polipeptídeo isolado
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Also Published As

Publication number Publication date
WO2008124048A8 (en) 2011-11-03
ES2559312T3 (es) 2016-02-11
BRPI0808577A2 (pt) 2019-09-24
EP2129777A2 (en) 2009-12-09
RS20090413A (sr) 2010-06-30
CN101765658A (zh) 2010-06-30
US20150031096A1 (en) 2015-01-29
CA2679988A1 (en) 2008-10-16
US20080254191A1 (en) 2008-10-16
US8828690B2 (en) 2014-09-09
CN101765658B (zh) 2013-11-20
HUE028692T2 (en) 2016-12-28
AU2008236723A1 (en) 2008-10-16
CN104152423A (zh) 2014-11-19
EP2129777B1 (en) 2015-10-28
RU2014102130A (ru) 2015-08-27
WO2008124048A2 (en) 2008-10-16
RU2517608C2 (ru) 2014-05-27
JP2010523113A (ja) 2010-07-15
DK2129777T3 (en) 2016-01-25
WO2008124048A3 (en) 2009-02-05
UA103595C2 (uk) 2013-11-11
RU2009140397A (ru) 2011-05-10

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