BRPI0615446A2 - uso do composto ácido(+) 1,4-dihidro-7-[(3s,4s)-3-metóxi-4-(metilamino)-1-pirrolid inil]-4-oxo-1-(2-tiazolil)-1,8-naftiridina-3-carboxìlico enantiomericamente puro, e, composto ácido(+) 1,4-dihidro-7-[3s,4s)-3-metóxi-4-(metilamino)-1-pirrolidi nil]-4-oxo-1-(2-tiazolil)-1,8-naftiridina -3-carboxìlico enantiomericamente puro - Google Patents

uso do composto ácido(+) 1,4-dihidro-7-[(3s,4s)-3-metóxi-4-(metilamino)-1-pirrolid inil]-4-oxo-1-(2-tiazolil)-1,8-naftiridina-3-carboxìlico enantiomericamente puro, e, composto ácido(+) 1,4-dihidro-7-[3s,4s)-3-metóxi-4-(metilamino)-1-pirrolidi nil]-4-oxo-1-(2-tiazolil)-1,8-naftiridina -3-carboxìlico enantiomericamente puro Download PDF

Info

Publication number: BRPI0615446A2
Authority: BR; Brazil
Prior art keywords: dose; cancer; use according; leukemia; sns
Prior art date: 2005-09-02

Application number

BRPI0615446-8A

Other languages

English (en)

Portuguese (pt)

Inventor

Jeffrey A Silverman

Michael Arkin

Jennifer Hyde

Duncan Walker

Jasmin Wright

Daniel C Adelman

Original Assignee

Sunesis Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-09-02

Filing date

2006-09-05

Publication date

2011-05-17

2005-09-02 Priority claimed from US11/218,653 external-priority patent/US20060063795A1/en

2006-09-05 Application filed by Sunesis Pharmaceuticals Inc filed Critical Sunesis Pharmaceuticals Inc

2006-09-05 Priority claimed from PCT/US2006/034699 external-priority patent/WO2007028171A1/en

2011-05-17 Publication of BRPI0615446A2 publication Critical patent/BRPI0615446A2/pt

Links

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229960004355 vindesine Drugs 0.000 description 1
UGGWPQSBPIFKDZ-KOTLKJBCSA-N vindesine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(N)=O)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1N=C1[C]2C=CC=C1 UGGWPQSBPIFKDZ-KOTLKJBCSA-N 0.000 description 1
229960005212 vindesine sulfate Drugs 0.000 description 1
BCXOZISMDZTYHW-IFQBWSDRSA-N vinepidine sulfate Chemical compound OS(O)(=O)=O.C([C@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C=O)C=2)OC)C[C@@H](C2)CC)N2CCC2=C1NC1=CC=CC=C21 BCXOZISMDZTYHW-IFQBWSDRSA-N 0.000 description 1
229960002166 vinorelbine tartrate Drugs 0.000 description 1
GBABOYUKABKIAF-IWWDSPBFSA-N vinorelbinetartrate Chemical compound C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC(C23[C@H]([C@@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC GBABOYUKABKIAF-IWWDSPBFSA-N 0.000 description 1
238000012800 visualization Methods 0.000 description 1
238000005406 washing Methods 0.000 description 1
239000008215 water for injection Substances 0.000 description 1
239000008136 water-miscible vehicle Substances 0.000 description 1
238000009736 wetting Methods 0.000 description 1
239000000080 wetting agent Substances 0.000 description 1
229940053867 xeloda Drugs 0.000 description 1
229950005561 zanoterone Drugs 0.000 description 1
229910052725 zinc Inorganic materials 0.000 description 1
239000011701 zinc Substances 0.000 description 1
XRASPMIURGNCCH-UHFFFAOYSA-N zoledronic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(O)CN1C=CN=C1 XRASPMIURGNCCH-UHFFFAOYSA-N 0.000 description 1
229960004276 zoledronic acid Drugs 0.000 description 1
150000003952 β-lactams Chemical class 0.000 description 1

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Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BRPI0615446-8A 2005-09-02 2006-09-05 uso do composto ácido(+) 1,4-dihidro-7-[(3s,4s)-3-metóxi-4-(metilamino)-1-pirrolid inil]-4-oxo-1-(2-tiazolil)-1,8-naftiridina-3-carboxìlico enantiomericamente puro, e, composto ácido(+) 1,4-dihidro-7-[3s,4s)-3-metóxi-4-(metilamino)-1-pirrolidi nil]-4-oxo-1-(2-tiazolil)-1,8-naftiridina -3-carboxìlico enantiomericamente puro BRPI0615446A2 (pt)

Applications Claiming Priority (11)

Application Number	Priority Date	Filing Date	Title
US11/218,653 US20060063795A1 (en)	2004-03-15	2005-09-02	SNS-595 and methods of using the same
US11/218,653		2005-09-02
US11/218,387 US20060025437A1 (en)	2004-03-15	2005-09-02	SNS-595 and methods of using the same
US11/218,387		2005-09-02
US78909306P	2006-04-03	2006-04-03
US78892706P	2006-04-03	2006-04-03
US60/788,927		2006-04-03
US60/789,093		2006-04-03
US81028506P	2006-06-01	2006-06-01
US60/810,285		2006-06-01
PCT/US2006/034699 WO2007028171A1 (en)	2005-09-02	2006-09-05	Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer

Publications (1)

Publication Number	Publication Date
BRPI0615446A2 true BRPI0615446A2 (pt)	2011-05-17

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Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0615446-8A BRPI0615446A2 (pt)	2005-09-02	2006-09-05	uso do composto ácido(+) 1,4-dihidro-7-[(3s,4s)-3-metóxi-4-(metilamino)-1-pirrolid inil]-4-oxo-1-(2-tiazolil)-1,8-naftiridina-3-carboxìlico enantiomericamente puro, e, composto ácido(+) 1,4-dihidro-7-[3s,4s)-3-metóxi-4-(metilamino)-1-pirrolidi nil]-4-oxo-1-(2-tiazolil)-1,8-naftiridina -3-carboxìlico enantiomericamente puro

Country Status (2)

Country	Link
BR (1)	BRPI0615446A2 (es)
MX (1)	MX2008002843A (es)

2006
- 2006-09-05 MX MX2008002843A patent/MX2008002843A/es active IP Right Grant
- 2006-09-05 BR BRPI0615446-8A patent/BRPI0615446A2/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
MX2008002843A (es)	2008-09-08

Publication	Publication Date	Title
DK2049109T3 (en)	2016-01-11	Combined use of (+) - 1,4-dihydro-7 - [(3S, 4S) -3-methoxy-4- (methylamino) -1-pyrrolidinyl] -4-oxo-1- (2-thiazolyl) -1,8-naphthyridine-3-carboxylic acid and cytarabine (Ara-C) for the treatment of leukemia
CA2708264C (en)	2018-07-03	Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders
US20180098975A1 (en)	2018-04-12	Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
US12090147B2 (en)	2024-09-17	Combination therapy with 2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide
BR112021012578A2 (pt)	2021-09-08	Composições e métodos de uso de 2-(4-clorofenil)-n-((2-(2,6-dioxopiperidin-3-il)-1-oxoisoindolin-5-il)metil)-2,2-difluoroacetamida
AU2006287149B2 (en)	2013-05-23	Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
US20110293745A1 (en)	2011-12-01	Aurora kinase inhibitors
RU2592231C2 (ru)	2016-07-20	Способы применения (+)-1,4-дигидро-7-[(3s, 4s)-3-метокси-4-(метиламино)-1-пирролидинил]-4-оксо-1-(2-тиазолил)-1,8-нафтиридин-3-карбоновой кислоты для лечения рака
BRPI0615446A2 (pt)	2011-05-17	uso do composto ácido(+) 1,4-dihidro-7-[(3s,4s)-3-metóxi-4-(metilamino)-1-pirrolid inil]-4-oxo-1-(2-tiazolil)-1,8-naftiridina-3-carboxìlico enantiomericamente puro, e, composto ácido(+) 1,4-dihidro-7-[3s,4s)-3-metóxi-4-(metilamino)-1-pirrolidi nil]-4-oxo-1-(2-tiazolil)-1,8-naftiridina -3-carboxìlico enantiomericamente puro
RU2428983C2 (ru)	2011-09-20	Способы применения (+)-1,4-дигидро-7-[(3s,4s)-3-метокси-4-(метиламино)-1-пирролидинил]-4-оксо-1-(2-тиазолил)-1,8-нафтиридин-3-карбоновой кислоты для лечения рака
AU2013219242B2 (en)	2016-05-19	Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
AU2016210657A1 (en)	2016-08-18	Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
CN104873502A (zh)	2015-09-02	使用(+)-1,4-二氢-7-[(3s,4s)-3-甲氧基-4-(甲氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸治疗癌症的方法
CN101296697A (zh)	2008-10-29	使用(+)-1,4-二氢-7-[(3s,4s)-3-甲氧基-4-(甲氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸治疗癌症的方法
HK1224955A1 (en)	2017-09-01	Combined use of (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid and cytarabine (ara-c) for the treatment of leukemia

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