BRPI0607975A2 - forma farmacêutica contendo oxicodona e naloxona - Google Patents
forma farmacêutica contendo oxicodona e naloxonaInfo
- Publication number
- BRPI0607975A2 BRPI0607975A2 BRPI0607975-0A BRPI0607975A BRPI0607975A2 BR PI0607975 A2 BRPI0607975 A2 BR PI0607975A2 BR PI0607975 A BRPI0607975 A BR PI0607975A BR PI0607975 A2 BRPI0607975 A2 BR PI0607975A2
- Authority
- BR
- Brazil
- Prior art keywords
- naloxone
- dosage form
- sub
- form containing
- containing oxycodone
- Prior art date
Links
- BRUQQQPBMZOVGD-XFKAJCMBSA-N Oxycodone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(OC)C2=C5[C@@]13CCN4C BRUQQQPBMZOVGD-XFKAJCMBSA-N 0.000 title abstract 2
- 239000002552 dosage form Substances 0.000 title abstract 2
- UZHSEJADLWPNLE-GRGSLBFTSA-N naloxone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(O)C2=C5[C@@]13CCN4CC=C UZHSEJADLWPNLE-GRGSLBFTSA-N 0.000 title abstract 2
- 229960004127 naloxone Drugs 0.000 title abstract 2
- 229960002085 oxycodone Drugs 0.000 title abstract 2
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003871 intestinal function Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
FORMA FARMACêUTICA CONTENDO OXICODONA E NALOXONA. A presente invenção se refere a uma forma farmacêutica que compreende oxicodona e naloxona e que é caracterizada por parâmetros específicos in vivo como t~ max~, C~ max~, valor AUCt, classificação da função intestinal média e/ou a duração da eficácia analgésica.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05004377A EP1695700A1 (en) | 2005-02-28 | 2005-02-28 | Dosage form containing oxycodone and naloxone |
| PCT/EP2006/060341 WO2006089973A2 (en) | 2005-02-28 | 2006-02-28 | Dosage form containing oxycodone and naloxone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0607975A2 true BRPI0607975A2 (pt) | 2009-10-27 |
Family
ID=34933990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0607975-0A BRPI0607975A2 (pt) | 2005-02-28 | 2006-02-28 | forma farmacêutica contendo oxicodona e naloxona |
Country Status (26)
| Country | Link |
|---|---|
| US (5) | US20080145429A1 (pt) |
| EP (5) | EP1695700A1 (pt) |
| JP (2) | JP2008531650A (pt) |
| KR (1) | KR20070107805A (pt) |
| CN (2) | CN101128191A (pt) |
| AT (1) | ATE517611T1 (pt) |
| AU (2) | AU2006217870B2 (pt) |
| BR (1) | BRPI0607975A2 (pt) |
| CA (3) | CA2599156C (pt) |
| CY (1) | CY1111967T1 (pt) |
| DE (2) | DE19167974T1 (pt) |
| DK (2) | DK1855657T3 (pt) |
| ES (1) | ES2370409T3 (pt) |
| FI (1) | FI7750U1 (pt) |
| HR (1) | HRP20110775T1 (pt) |
| IL (2) | IL185514A0 (pt) |
| ME (1) | ME01262B (pt) |
| MX (1) | MX2007010494A (pt) |
| NZ (1) | NZ588875A (pt) |
| PL (1) | PL1855657T3 (pt) |
| PT (1) | PT1855657E (pt) |
| RS (1) | RS51984B (pt) |
| RU (1) | RU2428985C2 (pt) |
| SI (1) | SI1855657T1 (pt) |
| UA (1) | UA93543C2 (pt) |
| WO (1) | WO2006089973A2 (pt) |
Families Citing this family (70)
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| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| EP1604667A1 (en) * | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioids for the treatment of the restless leg syndrome |
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| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| GEP20105052B (en) * | 2005-01-28 | 2010-07-26 | Euro Celtique Sa | Alcohol resistant dosage forms |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| EP1702558A1 (en) | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Method and device for the assessment of bowel function |
| EP1695700A1 (en) | 2005-02-28 | 2006-08-30 | Euro-Celtique S.A. | Dosage form containing oxycodone and naloxone |
| DE202006018609U1 (de) * | 2006-08-29 | 2007-05-16 | Euro-Celtique S.A. | Verwendung von Opioidformulierungen in nadellosen Vorrichtungen zur Medikamentenverabreichung |
| EA201100544A1 (ru) * | 2006-11-07 | 2012-01-30 | Нектар Терапьютикс | Применение комбинации опиоидного агониста и конъюгата полимер-опиоидный антагонист для изготовления лекарственного средства для лечения и предупреждения боли |
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| EP2042176A1 (en) * | 2007-09-26 | 2009-04-01 | Euro-Celtique S.A. | Use of a combination of an opioid agonist and an opioid antagonist for the treatment of Crohn's disease |
| KR20100121463A (ko) | 2007-12-17 | 2010-11-17 | 라보팜 인코포레이트 | 오용 예방적 방출 제어형 제제 |
| AU2009207796B2 (en) | 2008-01-25 | 2014-03-27 | Grunenthal Gmbh | Pharmaceutical dosage form |
| HRP20161307T1 (hr) | 2008-05-09 | 2016-12-02 | Grünenthal GmbH | Postupak za pripravu praškaste formulacije međuproizvoda i konačni kruti oblik doziranja uz korištenje koraka zgrušavanja raspršivanjem |
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- 2006-02-28 BR BRPI0607975-0A patent/BRPI0607975A2/pt not_active Application Discontinuation
- 2006-02-28 EP EP15180143.8A patent/EP2962686B1/en not_active Revoked
- 2006-02-28 JP JP2007557493A patent/JP2008531650A/ja not_active Withdrawn
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- 2006-02-28 DE DE202006020095U patent/DE202006020095U1/de not_active Expired - Lifetime
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