BRPI0606803A2 - axmi-018, axmi-020 e axmi-021, uma famìlia de genes de delta-endotoxina e métodos para seu uso - Google Patents
axmi-018, axmi-020 e axmi-021, uma famìlia de genes de delta-endotoxina e métodos para seu usoInfo
- Publication number
- BRPI0606803A2 BRPI0606803A2 BRPI0606803-0A BRPI0606803A BRPI0606803A2 BR PI0606803 A2 BRPI0606803 A2 BR PI0606803A2 BR PI0606803 A BRPI0606803 A BR PI0606803A BR PI0606803 A2 BRPI0606803 A2 BR PI0606803A2
- Authority
- BR
- Brazil
- Prior art keywords
- axmi
- methods
- plants
- compositions
- bacteria
- Prior art date
Links
- 239000002158 endotoxin Substances 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 241000894006 Bacteria Species 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 108091026890 Coding region Proteins 0.000 abstract 1
- 108020004414 DNA Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 230000000361 pesticidal effect Effects 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8281—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for bacterial resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8285—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for nematode resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Pest Control & Pesticides (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Insects & Arthropods (AREA)
- Crystallography & Structural Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Agronomy & Crop Science (AREA)
- Virology (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Abstract
AXMI-018, AXMI-020 E AXMI-021, UMA FAMìLIA DE GENES DE DELTA-ENDOTOXINA E MéTODOS PARA SEU USO. Composições e métodos para conferir atividade pesticida à bactérias, plantas, células, tecidos e sementes de planta são proporcionados. Composições compreendendo uma seqúência de codificação para um polipeptídeo de deita-endotoxina são proporcionadas. As seqúências de codificação podem ser usadas em estruturas de DNA ou cassetes de expressão para transformação e expressão em plantas e bactérias. Composições também compreendem bactérias, plantas, células, tecidos e sementes de planta transformados. Em particular, moléculas de ácido nucleico de delta-endotoxina isoladas são proporcionadas. Adicionalmente, seqúências de aminoácido correspondendo aos polinucleotídeos são abrangidas. Em particular, a presente invenção proporciona moléculas de ácido nucleico isoladas compreendendo seqúências de nucleotídeo que codificam a seqúência de aminoácido mostrada em SEQ ID NO: 2, 4 ou 6 ou a seqúência de nucleotídeo apresentada em SEQ ID NO: 1, 3 ou 5, bem como variantes e fragmentos das mesmas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64857805P | 2005-01-31 | 2005-01-31 | |
| PCT/US2006/003434 WO2006083891A2 (en) | 2005-01-31 | 2006-01-31 | Axmi-018, axmi-020, and axmi-021, a family of delta-endotoxin genes and methods for their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0606803A2 true BRPI0606803A2 (pt) | 2009-07-14 |
Family
ID=36777850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0606803-0A BRPI0606803A2 (pt) | 2005-01-31 | 2006-01-31 | axmi-018, axmi-020 e axmi-021, uma famìlia de genes de delta-endotoxina e métodos para seu uso |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20060212965A1 (pt) |
| EP (1) | EP1844064B1 (pt) |
| AU (1) | AU2006210880B2 (pt) |
| BR (1) | BRPI0606803A2 (pt) |
| CA (1) | CA2595901C (pt) |
| MX (1) | MX2007009206A (pt) |
| NZ (1) | NZ560935A (pt) |
| WO (1) | WO2006083891A2 (pt) |
Families Citing this family (78)
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| AU2006210880B2 (en) * | 2005-01-31 | 2012-09-20 | Athenix Corporation | AXMI-018, AXMI-020, and AXMI-021, a family of delta-endotoxin genes and methods for their use |
| US8609936B2 (en) | 2007-04-27 | 2013-12-17 | Monsanto Technology Llc | Hemipteran-and coleopteran active toxin proteins from Bacillus thuringiensis |
| US8129594B2 (en) * | 2008-06-11 | 2012-03-06 | Pioneer Hi-Bred International, Inc. | Bacillus thuringiensis gene with lepidopteran activity |
| WO2010027793A1 (en) * | 2008-08-25 | 2010-03-11 | Dow Agrosciences Llc | Nematode-resistant plants, and modified bacillus thuringiensis cry genes and proteins |
| BRPI0918840A2 (pt) * | 2008-08-25 | 2015-08-18 | Dow Agrosciences Llc | Vetor de expressão de planta, proteína modificada, método de produção da referida proteína e método para inibição de um nematoide |
| AR075634A1 (es) * | 2009-02-27 | 2011-04-20 | Athenix Corp | Proteinas pesticidas y metodos de uso de las mismas |
| AU2013205249B2 (en) * | 2009-07-31 | 2016-05-19 | Athenix Corp. | Axmi-192 family of pesticidal genes and methods for their use |
| EP2459587B1 (en) * | 2009-07-31 | 2016-03-16 | Athenix Corporation | Axmi-192 family of pesticidal genes and methods for their use |
| WO2011050271A1 (en) | 2009-10-23 | 2011-04-28 | Monsanto Technology Llc | Methods and compositions for expression of transgenes in plants |
| WO2011084324A2 (en) * | 2009-12-21 | 2011-07-14 | Pioneer Hi-Bred International, Inc. | Novel bacillus thuringiensis gene with lepidopteran activity |
| WO2011084314A2 (en) * | 2009-12-21 | 2011-07-14 | Pioneer Hi-Bred International, Inc. | Novel bacillus thuringiensis gene with coleopteran activity |
| BR112012018108A2 (pt) | 2010-01-22 | 2015-10-20 | Bayer Ip Gmbh | combinações acaricidas e/ou inseticidas de ingredientes ativos |
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| WO2025264577A1 (en) | 2024-06-20 | 2025-12-26 | Genective Sa | Insecticidal proteins, compositions and methods of use |
| WO2025264584A1 (en) | 2024-06-20 | 2025-12-26 | Genective Sa | Insecticidal proteins, compositions and methods of use |
| WO2026006045A1 (en) | 2024-06-25 | 2026-01-02 | Genective Sa | Insecticidal proteins, compositions and methods of use |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4196265A (en) | 1977-06-15 | 1980-04-01 | The Wistar Institute | Method of producing antibodies |
| US5589382A (en) * | 1990-07-27 | 1996-12-31 | Mycogen Corporation | Bacillus thuringiensis genes encoding nematode-active toxins |
| US5670365A (en) * | 1995-10-06 | 1997-09-23 | Mycogen Corporation | Identification of, and uses for, nematicidal bacillus thuringiensis genes, toxins, and isolates |
| AU2006210880B2 (en) * | 2005-01-31 | 2012-09-20 | Athenix Corporation | AXMI-018, AXMI-020, and AXMI-021, a family of delta-endotoxin genes and methods for their use |
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2006
- 2006-01-31 AU AU2006210880A patent/AU2006210880B2/en not_active Ceased
- 2006-01-31 MX MX2007009206A patent/MX2007009206A/es active IP Right Grant
- 2006-01-31 NZ NZ560935A patent/NZ560935A/en not_active IP Right Cessation
- 2006-01-31 EP EP20060734133 patent/EP1844064B1/en not_active Expired - Lifetime
- 2006-01-31 BR BRPI0606803-0A patent/BRPI0606803A2/pt not_active Application Discontinuation
- 2006-01-31 US US11/343,533 patent/US20060212965A1/en not_active Abandoned
- 2006-01-31 CA CA 2595901 patent/CA2595901C/en not_active Expired - Fee Related
- 2006-01-31 WO PCT/US2006/003434 patent/WO2006083891A2/en not_active Ceased
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2008
- 2008-08-15 US US12/192,904 patent/US20090100543A1/en not_active Abandoned
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|---|---|
| CA2595901A1 (en) | 2006-08-10 |
| EP1844064B1 (en) | 2013-01-30 |
| CA2595901C (en) | 2015-02-17 |
| WO2006083891A2 (en) | 2006-08-10 |
| MX2007009206A (es) | 2008-02-19 |
| WO2006083891A3 (en) | 2006-11-30 |
| EP1844064A2 (en) | 2007-10-17 |
| US20060212965A1 (en) | 2006-09-21 |
| NZ560935A (en) | 2009-06-26 |
| AU2006210880A1 (en) | 2006-08-10 |
| US20090100543A1 (en) | 2009-04-16 |
| AU2006210880B2 (en) | 2012-09-20 |
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