BRPI0606539A2 - vacinas aperfeiçoadas contra a prrs - Google Patents
vacinas aperfeiçoadas contra a prrsInfo
- Publication number
- BRPI0606539A2 BRPI0606539A2 BRPI0606539-2A BRPI0606539A BRPI0606539A2 BR PI0606539 A2 BRPI0606539 A2 BR PI0606539A2 BR PI0606539 A BRPI0606539 A BR PI0606539A BR PI0606539 A2 BRPI0606539 A2 BR PI0606539A2
- Authority
- BR
- Brazil
- Prior art keywords
- vaccines
- prrs vaccines
- improved
- improved prrs
- prrs
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 208000005342 Porcine Reproductive and Respiratory Syndrome Diseases 0.000 abstract 2
- 241001135989 Porcine reproductive and respiratory syndrome virus Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
VACINAS APERFEIçOADAS CONTRA A PRRS. A presente invenção refere-se as vacinas contra PRRS com vírus vivos modificados aperfeiçoadas de genótipo Europeu e novas cepas de PRRSV que podem ser usadas para a fabricação de tais vacinas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05000542 | 2005-01-13 | ||
| PCT/EP2006/050098 WO2006074986A2 (en) | 2005-01-13 | 2006-01-09 | Prrs vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0606539A2 true BRPI0606539A2 (pt) | 2009-06-30 |
Family
ID=36677986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0606539-2A BRPI0606539A2 (pt) | 2005-01-13 | 2006-01-09 | vacinas aperfeiçoadas contra a prrs |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7368117B2 (pt) |
| EP (1) | EP1838343B1 (pt) |
| JP (1) | JP2008526921A (pt) |
| KR (1) | KR20070096019A (pt) |
| CN (1) | CN101189027A (pt) |
| AR (1) | AR053327A1 (pt) |
| AT (1) | ATE462445T1 (pt) |
| AU (1) | AU2006205852A1 (pt) |
| BR (1) | BRPI0606539A2 (pt) |
| CA (1) | CA2587321A1 (pt) |
| DE (1) | DE602006013270D1 (pt) |
| ES (1) | ES2343201T3 (pt) |
| MY (1) | MY139896A (pt) |
| RU (1) | RU2007130801A (pt) |
| WO (1) | WO2006074986A2 (pt) |
| ZA (1) | ZA200703663B (pt) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0839912A1 (en) * | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| US20040224327A1 (en) * | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| FR2772047B1 (fr) | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
| EP1157121B1 (en) | 1999-03-08 | 2013-04-24 | Boehringer Ingelheim Vetmedica GmbH | Prrsv replicon |
| JP4778620B2 (ja) | 1999-04-22 | 2011-09-21 | ユナイテッド ステイツ デパートメント オブ アグリカルチャー | 分離株ja−142に基づく、豚繁殖・呼吸障害症候群ワクチン |
| EP1781327A4 (en) | 2004-06-18 | 2009-02-25 | Univ Minnesota | IDENTIFICATION OF VIRAL INFECTED AND VACCINATED ORGANISMS |
| US7632636B2 (en) | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
| UA95602C2 (ru) | 2004-12-30 | 2011-08-25 | Берингер Ингельхейм Ветмедика, Инк. | Иммуногенная композиция цвс2 и способы приготовления такой композиции |
| US7833707B2 (en) * | 2004-12-30 | 2010-11-16 | Boehringer Ingelheim Vetmedica, Inc. | Methods of overexpression and recovery of porcine circovirus type 2 ORF2 |
| US7700285B1 (en) | 2005-12-29 | 2010-04-20 | Boehringer Ingelheim Vetmedica, Inc. | PCV2 immunogenic compositions and methods of producing such compositions |
| PL2369001T3 (pl) | 2005-06-24 | 2017-06-30 | Regents Of The University Of Minnesota | Wirusy PRRS, ich klony zakaźne, mutanty i sposoby stosowania |
| ES2572736T3 (es) | 2005-12-29 | 2016-06-02 | Boehringer Ingelheim Vetmedica, Inc. | Uso de una composición inmunógena para atenuar síntomas clínicos en cerdos |
| BR122015028489B1 (pt) | 2005-12-29 | 2021-10-13 | Boehringer Ingelheim Animal Health Usa Inc | Vacina de combinação multivalente contra pcv2, bem como uso de uma proteína orf2 na preparação da mesma |
| US20100136060A1 (en) * | 2006-11-22 | 2010-06-03 | Boehringer Ingelheim Vetmedica, Inc. | Methods of reducing porcine circovirus-associated disease outbreaks |
| EP2859900A1 (en) * | 2006-12-11 | 2015-04-15 | Boehringer Ingelheim Vetmedica, Inc. | Effective method of treatment of porcine circovirus and lawsonia intracellularis infections |
| AU2007333857B2 (en) * | 2006-12-15 | 2014-05-15 | Boehringer Ingelheim Animal Health USA Inc. | Treatment of pigs with PCV2 antigen |
| EP1941903A1 (en) | 2007-01-03 | 2008-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Prophylaxis and treatment of PRDC |
| EP1958644A1 (en) | 2007-02-13 | 2008-08-20 | Boehringer Ingelheim Vetmedica Gmbh | Prevention and treatment of sub-clinical pcvd |
| CN100439494C (zh) * | 2007-03-14 | 2008-12-03 | 中国动物疫病预防控制中心 | 猪繁殖与呼吸综合征疫苗、制备方法及应用 |
| WO2008121958A1 (en) * | 2007-04-02 | 2008-10-09 | Boehringer Ingelheim Vetmedica, Inc. | Use of prrsv vaccines to reduce pcv2 viremia |
| US7829274B2 (en) | 2007-09-04 | 2010-11-09 | Boehringer Ingelheim Vetmedica, Inc. | Reduction of concomitant infections in pigs by the use of PCV2 antigen |
| KR20100103535A (ko) * | 2007-12-31 | 2010-09-27 | 베링거잉겔하임베트메디카인코퍼레이티드 | 외래 아미노산 삽입물을 갖는 pcv2 orf2 바이러스 유사 입자 |
| WO2009126356A2 (en) | 2008-01-23 | 2009-10-15 | Boehringer Ingelheim Vetmedica, Inc. | Pcv2 mycoplasma hyopneumoniae immunogenic compositions and methods of producing such compositions |
| US20100003278A1 (en) * | 2008-07-03 | 2010-01-07 | Boehringer Ingelheim Vetmedica, Inc. | Immunological Compositions Effective for Lessening the Severity or Incidence of PRRSV Signs and Methods of Use Thereof |
| AU2009285843B2 (en) * | 2008-08-25 | 2014-07-17 | Boehringer Ingelheim Vetmedica Inc | Vaccine against Highly Pathogenic Porcine Reproductive and Respiratory Syndrome (HP PRRS) |
| TWI627281B (zh) | 2009-09-02 | 2018-06-21 | 百靈佳殷格翰家畜藥品公司 | 降低pcv-2組合物殺病毒活性之方法及具有改良免疫原性之pcv-2組合物 |
| FR2957803B1 (fr) * | 2010-03-24 | 2012-06-01 | Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic | Diluants adjuvants de vaccins vivants pour maladies porcines |
| DK2558118T3 (da) * | 2010-04-16 | 2019-08-26 | Univ Gent | Krydsbeskyttende vaccine mod reproduktions- og respirationssyndromvirus hos svin |
| UA117272C2 (uk) | 2011-02-17 | 2018-07-10 | Бьорінгер Інгельхайм Ветмедіка Гмбх | Новий європейський штам prrsv |
| CN103370077B (zh) | 2011-02-17 | 2016-10-26 | 贝林格尔.英格海姆维特梅迪卡有限公司 | 猪繁殖与呼吸综合征病毒的商业化规模生产方法 |
| WO2012177739A2 (en) | 2011-06-20 | 2012-12-27 | Siemens Healthcare Diagnostics Inc. | Reagents and methods for detecting hcv |
| KR101281361B1 (ko) * | 2011-07-18 | 2013-07-02 | 서울대학교산학협력단 | 북미형 돼지 생식기 호흡기 증후군 바이러스 예방 백신 조성물 및 이를 포함하는 혼합백신 조성물 |
| WO2013017568A1 (en) | 2011-07-29 | 2013-02-07 | Boehringer Ingelheim Vetmedica Gmbh | INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF |
| US9187731B2 (en) | 2011-07-29 | 2015-11-17 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus inducing type I interferon in susceptible cells |
| UA114504C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs |
| UA114503C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv та mycoplasma hyopneumoniae |
| US9120859B2 (en) | 2012-04-04 | 2015-09-01 | Zoetis Services Llc | Mycoplasma hyopneumoniae vaccine |
| US9457073B2 (en) * | 2012-09-26 | 2016-10-04 | University Of Manitoba | Live attenuated replication-competent arteriviruses having decreased dub/deisgylating activity |
| CN105308178B (zh) * | 2012-12-07 | 2019-06-07 | 伊利诺伊大学评议会 | 猪繁殖与呼吸综合征病毒组合物及其用途 |
| CN105073130A (zh) | 2013-03-15 | 2015-11-18 | 勃林格殷格翰动物保健公司 | 猪生殖与呼吸综合征病毒、组合物、疫苗及使用方法 |
| US9987348B2 (en) | 2013-09-25 | 2018-06-05 | Zoetis Services Llc | PCV2B divergent vaccine composition and methods of use |
| US9505808B2 (en) | 2013-10-02 | 2016-11-29 | Boehringer Ingelheim Vetmedica, Inc. | PCV2 ORF2 protein variant and virus like particles composed thereof |
| MX2020010248A (es) | 2013-12-20 | 2020-10-16 | Boehringer Ingelheim Vetmedica Gmbh | Variante del virus prrs, clon de adnc del virus europeo y sus usos. |
| EP3432920A1 (en) | 2016-03-23 | 2019-01-30 | Intervet International B.V. | A vaccine for intradermal application against pcv2 and prrs virus infection |
| CN108697782A (zh) | 2016-03-23 | 2018-10-23 | 英特维特国际股份有限公司 | 针对pcv2病毒和猪肺炎支原体感染的组合疫苗 |
| RU2018137036A (ru) | 2016-03-23 | 2020-04-23 | Интервет Интернэшнл Б.В. | Комбинированная вакцина против инфекции вирусами pcv2 и prrs, содержащая альбумин |
| WO2018099889A1 (en) | 2016-11-29 | 2018-06-07 | Intervet International B.V. | Swine vaccine |
| CN110446502B (zh) | 2017-04-13 | 2024-01-26 | 英特维特国际股份有限公司 | 用于联合非混合使用的含猪病原体的疫苗 |
| MX2022013080A (es) | 2020-04-20 | 2022-11-10 | Intervet Int Bv | Una combinacion de vacunas para el tratamiento profilactico de un cerdo. |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2069435T4 (es) | 1991-06-06 | 1997-06-16 | Stichting Centr Diergeneeskund | Composicion de vacuna para vacunar animales, en concreto mamiferos y mas concretamente cerdos o cochinos. |
| US6042830A (en) * | 1992-08-05 | 2000-03-28 | Boehringer Ingelheim Vetmedica, Inc. | Viral agent associated with mystery swine disease |
| DE69214657T2 (de) | 1991-08-26 | 1997-04-17 | David Allen Benfield | Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas) |
| WO1993006211A1 (en) | 1991-09-16 | 1993-04-01 | Collins James E | Vaccine for mystery swine disease and method for diagnosis thereof |
| HU220113B (hu) | 1991-10-14 | 2001-11-28 | Akzo N.V. | Sertések reproduktív és légzőszervi tünetegyüttese elleni vakcina, eljárás előállítására és alkalmazása |
| DE69522984T2 (de) * | 1994-04-11 | 2002-04-25 | Akzo Nobel Nv | Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Schweins |
| ATE268783T1 (de) | 1995-03-14 | 2004-06-15 | Akzo Nobel Nv | Expression in der selben zelle von polypeptide vom schweinen reproduktiven und respiratorischen syndrom |
| DE69704011T2 (de) * | 1996-10-09 | 2001-06-07 | Akzo Nobel Nv | Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Sweins (PRRSV) |
| EP0839912A1 (en) | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| CA2440933A1 (en) | 1998-12-22 | 2000-06-22 | Pfizer Products Inc. | An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof |
| US6841364B2 (en) | 2002-01-22 | 2005-01-11 | Protatek International, Inc. | Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof |
-
2006
- 2006-01-09 AU AU2006205852A patent/AU2006205852A1/en not_active Abandoned
- 2006-01-09 RU RU2007130801/13A patent/RU2007130801A/ru not_active Application Discontinuation
- 2006-01-09 ES ES06701253T patent/ES2343201T3/es not_active Expired - Lifetime
- 2006-01-09 CA CA002587321A patent/CA2587321A1/en not_active Abandoned
- 2006-01-09 BR BRPI0606539-2A patent/BRPI0606539A2/pt not_active IP Right Cessation
- 2006-01-09 DE DE602006013270T patent/DE602006013270D1/de not_active Expired - Lifetime
- 2006-01-09 JP JP2007550784A patent/JP2008526921A/ja active Pending
- 2006-01-09 AT AT06701253T patent/ATE462445T1/de not_active IP Right Cessation
- 2006-01-09 CN CNA2006800023295A patent/CN101189027A/zh active Pending
- 2006-01-09 KR KR1020077018568A patent/KR20070096019A/ko not_active Withdrawn
- 2006-01-09 EP EP06701253A patent/EP1838343B1/en not_active Expired - Lifetime
- 2006-01-09 WO PCT/EP2006/050098 patent/WO2006074986A2/en not_active Ceased
- 2006-01-11 MY MYPI20060125A patent/MY139896A/en unknown
- 2006-01-13 AR ARP060100135A patent/AR053327A1/es unknown
- 2006-01-13 US US11/275,552 patent/US7368117B2/en active Active
-
2007
- 2007-05-07 ZA ZA200703663A patent/ZA200703663B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE602006013270D1 (en) | 2010-05-12 |
| JP2008526921A (ja) | 2008-07-24 |
| AU2006205852A1 (en) | 2006-07-20 |
| MY139896A (en) | 2009-11-30 |
| CN101189027A (zh) | 2008-05-28 |
| ZA200703663B (en) | 2008-07-30 |
| KR20070096019A (ko) | 2007-10-01 |
| ES2343201T3 (es) | 2010-07-26 |
| WO2006074986A3 (en) | 2007-11-15 |
| WO2006074986A2 (en) | 2006-07-20 |
| US20060286123A1 (en) | 2006-12-21 |
| US7368117B2 (en) | 2008-05-06 |
| RU2007130801A (ru) | 2009-02-20 |
| AR053327A1 (es) | 2007-05-02 |
| ATE462445T1 (de) | 2010-04-15 |
| EP1838343B1 (en) | 2010-03-31 |
| CA2587321A1 (en) | 2006-07-20 |
| EP1838343A2 (en) | 2007-10-03 |
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| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
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