BRPI0516303A - método de produção de colágeno em planta ou em célula de planta isolada, planta geneticamente modificada ou célula de planta isolada, sistema de planta, método de produção de colágeno fibirilar e construção de ácido nucléico - Google Patents
método de produção de colágeno em planta ou em célula de planta isolada, planta geneticamente modificada ou célula de planta isolada, sistema de planta, método de produção de colágeno fibirilar e construção de ácido nucléicoInfo
- Publication number
- BRPI0516303A BRPI0516303A BRPI0516303-0A BRPI0516303A BRPI0516303A BR PI0516303 A BRPI0516303 A BR PI0516303A BR PI0516303 A BRPI0516303 A BR PI0516303A BR PI0516303 A BRPI0516303 A BR PI0516303A
- Authority
- BR
- Brazil
- Prior art keywords
- plant
- production method
- collagen production
- isolated
- plant cell
- Prior art date
Links
- 230000037319 collagen production Effects 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 2
- 238000010276 construction Methods 0.000 title 1
- 230000003619 fibrillary effect Effects 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 102200024044 rs1555523872 Human genes 0.000 abstract 3
- 108010035532 Collagen Proteins 0.000 abstract 2
- 102000008186 Collagen Human genes 0.000 abstract 2
- 101710096389 Collagen alpha chain Proteins 0.000 abstract 2
- 229920001436 collagen Polymers 0.000 abstract 2
- 238000009825 accumulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8273—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for drought, cold, salt resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Botany (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fertilizers (AREA)
- Enzymes And Modification Thereof (AREA)
- Cosmetics (AREA)
Abstract
MéTODO DE PRODUçãO DE COLáGENO EM PLANTA OU EM CéLULA DE PLANTA ISOLADA, PLANTA GENETICANENTE MODIFICADA OU CéLULA DE PLANTA ISOLADA, SISTEMA DE PLANTA, MéTODO DE PRODUçãO DE COLáGENO FIBIRILAR E CONSTRUçãO DE áCIDO NUCLéICO. Compreende um método para produzir colágeno em uma planta e plantas para produzir colágeno são estabelecidos; o método é efetuado exprimindo na planta pelo menos um tipo de colágeno da cadeia alfa de maneira a permitir a acumulação de colágeno da cadeia alfa em um compartimento subcelular livre de atividade endógena P4H, por meio disso produzindo o colágeno na planta.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61371904P | 2004-09-29 | 2004-09-29 | |
| US60/613,719 | 2004-09-29 | ||
| PCT/IL2005/001045 WO2006035442A2 (en) | 2004-09-29 | 2005-09-28 | Collagen producing plants and methods of generating and using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0516303A true BRPI0516303A (pt) | 2008-09-02 |
| BRPI0516303B1 BRPI0516303B1 (pt) | 2021-04-13 |
Family
ID=35788568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0516303-0A BRPI0516303B1 (pt) | 2004-09-29 | 2005-09-28 | Método de produção de colágeno em planta ou em célula de planta isolada |
Country Status (14)
| Country | Link |
|---|---|
| EP (6) | EP2816117B1 (pt) |
| JP (2) | JP5100386B2 (pt) |
| KR (1) | KR20070083870A (pt) |
| CN (1) | CN101065491B (pt) |
| AT (1) | ATE479762T1 (pt) |
| BR (1) | BRPI0516303B1 (pt) |
| CA (1) | CA2582051C (pt) |
| DE (1) | DE602005023332D1 (pt) |
| HK (1) | HK1251611B (pt) |
| IL (1) | IL182320A (pt) |
| MX (1) | MX2007003767A (pt) |
| NZ (1) | NZ554787A (pt) |
| WO (1) | WO2006035442A2 (pt) |
| ZA (1) | ZA200703369B (pt) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7378506B2 (en) | 1997-07-21 | 2008-05-27 | Ohio University | Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins |
| US6639050B1 (en) | 1997-07-21 | 2003-10-28 | Ohio University | Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins |
| JP2007521807A (ja) | 2004-01-14 | 2007-08-09 | オハイオ ユニバーシティ | 植物においてペプチド/タンパク質を産生する方法およびそれにより産生されたペプチド/タンパク質 |
| CA2573918A1 (en) | 2004-04-19 | 2005-11-24 | Ohio University | Cross-linkable glycoproteins and methods of making the same |
| EP2816117B1 (en) | 2004-09-29 | 2016-11-30 | Collplant Ltd. | Collagen producing plants and methods of generating and using same |
| US8455717B2 (en) | 2004-09-29 | 2013-06-04 | Collplant Ltd. | Collagen producing plants and methods of generating and using same |
| WO2008008766A2 (en) * | 2006-07-10 | 2008-01-17 | Ohio University | Co-expression of proline hydroxylases to facilitate hyp-glycosylation of proteins expressed and secreted in plant cells |
| EP2220246B1 (en) | 2007-10-26 | 2015-05-20 | Collplant Ltd. | Methods of processing recombinant procollagen |
| WO2009069123A2 (en) * | 2007-11-26 | 2009-06-04 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions comprising fibrous polypeptides and polysaccharides |
| CN104491845A (zh) * | 2008-04-18 | 2015-04-08 | 科尔普兰特有限公司 | 产生和使用原胶原的方法 |
| WO2011064773A1 (en) | 2009-11-24 | 2011-06-03 | Collplant Ltd. | Method of generating collagen fibers |
| EP2640877A2 (en) | 2010-11-16 | 2013-09-25 | Collplant Ltd. | Collagen structures and method of fabricating the same |
| US9687583B2 (en) | 2011-09-01 | 2017-06-27 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Adhesive biopolymers and uses thereof |
| WO2013093921A1 (en) | 2011-12-20 | 2013-06-27 | Collplant Ltd. | Collagen coated synthetic polymer fibers |
| KR102063686B1 (ko) * | 2012-01-02 | 2020-02-11 | (주)아모레퍼시픽 | 콩뿌리 추출물을 함유하는 피부 외용제 조성물 |
| US10053501B2 (en) | 2013-03-21 | 2018-08-21 | Commonwealth Scientific And Industrial Research Organisation | Purification of triple helical proteins |
| EP2976097B1 (en) | 2013-03-21 | 2021-05-26 | CollPlant Ltd. | Compositions comprising collagen and prp for tissue regeneration and their production method |
| GB201308120D0 (en) * | 2013-05-06 | 2013-06-12 | Baden Wuerttemberg Stiftung Gmbh | Recombinant protein and method for its production |
| US10155793B2 (en) | 2013-09-09 | 2018-12-18 | Commonwealth Scientific And Industrial Research Organisation | Modified bacterial collagen-like proteins |
| CN107810271B (zh) | 2014-11-20 | 2021-09-28 | 耶路撒冷希伯来大学伊萨姆研发公司 | 用于在植物细胞中生产具有改变的糖基化模式的多肽的组合物和方法 |
| JP7339889B2 (ja) | 2017-06-09 | 2023-09-06 | コルプラント リミテッド | 組換えコラーゲン含有配合物を使用した積層造形 |
| US20210032311A1 (en) * | 2017-09-25 | 2021-02-04 | Yu-Chun Wu | Non-human gene-edited mammal, protein crude extract separated from connective tissue of non-human gene-edited mammal, method for protein crude extract and uses of protein crude extract |
| ES2989582T3 (es) * | 2018-05-03 | 2024-11-27 | Collplant Ltd | Rellenos dérmicos y aplicaciones de los mismos |
| CN112823208A (zh) | 2018-07-31 | 2021-05-18 | 科弗朗有限公司 | 烟草转基因事件及用于检测与使用烟草转基因事件的方法 |
| CN109988234A (zh) * | 2019-02-20 | 2019-07-09 | 江苏悦智生物医药有限公司 | 酵母重组人源I型胶原α1链蛋白、合成方法及其应用 |
| EP4057833A1 (en) * | 2019-11-11 | 2022-09-21 | Kamcharov, Alexander Evgenievich | Beverage with collagen and additional additives |
| FR3105792B1 (fr) | 2019-12-26 | 2022-08-12 | Michel Assor | Matériau biocomposite collagène/matrice polymérique poreuse et son utilisation comme implant de réparation de lésions méniscales du genou et/ou de prévention ou de traitement de l’arthrose du genou |
| WO2021229577A1 (en) | 2020-05-12 | 2021-11-18 | Collplant Ltd. | Collagen as a delivery tool for metal-based anti-viral agents |
| CN119173524A (zh) | 2022-04-04 | 2024-12-20 | 斯威夫特制药有限责任公司 | 在植物中产生的重组蜘蛛丝强化的胶原蛋白及其应用 |
| CN119604615A (zh) * | 2022-08-02 | 2025-03-11 | 株式会社UniBio | 胶原蛋白产生方法 |
| CN117209592A (zh) * | 2023-07-26 | 2023-12-12 | 浙江大学 | 一种人源化i型胶原蛋白及其制备方法与应用 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| NL154599B (nl) | 1970-12-28 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking. |
| US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
| US3853987A (en) | 1971-09-01 | 1974-12-10 | W Dreyer | Immunological reagent and radioimmuno assay |
| US3867517A (en) | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
| NL171930C (nl) | 1972-05-11 | 1983-06-01 | Akzo Nv | Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen. |
| US3850578A (en) | 1973-03-12 | 1974-11-26 | H Mcconnell | Process for assaying for biologically active molecules |
| US3935074A (en) | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4034074A (en) | 1974-09-19 | 1977-07-05 | The Board Of Trustees Of Leland Stanford Junior University | Universal reagent 2-site immunoradiometric assay using labelled anti (IgG) |
| US3984533A (en) | 1975-11-13 | 1976-10-05 | General Electric Company | Electrophoretic method of detecting antigen-antibody reaction |
| US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
| US4879219A (en) | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
| CA1192510A (en) | 1981-05-27 | 1985-08-27 | Lawrence E. Pelcher | Rna plant virus vector or portion thereof, a method of construction thereof, and a method of producing a gene derived product therefrom |
| JPS6054684A (ja) | 1983-09-05 | 1985-03-29 | Teijin Ltd | 新規dνa及びハイブリツドdνa |
| US5011771A (en) | 1984-04-12 | 1991-04-30 | The General Hospital Corporation | Multiepitopic immunometric assay |
| US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| CA1288073C (en) | 1985-03-07 | 1991-08-27 | Paul G. Ahlquist | Rna transformation vector |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| GB8608850D0 (en) | 1986-04-11 | 1986-05-14 | Diatech Ltd | Packaging system |
| JPS6314693A (ja) | 1986-07-04 | 1988-01-21 | Sumitomo Chem Co Ltd | 植物ウイルスrnaベクタ− |
| ATE108828T1 (de) | 1987-02-09 | 1994-08-15 | Lubrizol Genetics Inc | Hybrides rns-virus. |
| US5316931A (en) | 1988-02-26 | 1994-05-31 | Biosource Genetics Corp. | Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes |
| US5693507A (en) | 1988-09-26 | 1997-12-02 | Auburn University | Genetic engineering of plant chloroplasts |
| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| US5593859A (en) * | 1991-10-23 | 1997-01-14 | Thomas Jefferson University | Synthesis of human procollagens and collagens in recombinant DNA systems |
| US5281521A (en) | 1992-07-20 | 1994-01-25 | The Trustees Of The University Of Pennsylvania | Modified avidin-biotin technique |
| FR2757874B1 (fr) * | 1996-12-17 | 2003-04-25 | Biocem | Collagenes recombinants et proteines derivees produits par les plantes, leurs procedes d'obtention et leurs utilisations |
| JP2001518305A (ja) | 1997-09-30 | 2001-10-16 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 植物種子におけるタンパク質製造 |
| CA2388432A1 (en) * | 1999-10-21 | 2001-04-26 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
| BR0015507A (pt) * | 1999-11-12 | 2002-10-22 | Fibrogen Inc | Gelatinas e colágenos animais |
| WO2001034647A2 (en) * | 1999-11-12 | 2001-05-17 | Fibrogen, Inc. | Animal collagens and gelatins |
| JP2005525081A (ja) * | 2001-06-05 | 2005-08-25 | カレン ケイ. オオイシ | 植物からの生物活性ミュラー管抑制物質を含むTGF−βタンパク質の遺伝子発現および産生法 |
| CN100366736C (zh) * | 2002-02-08 | 2008-02-06 | 诺维信公司 | 肌醇六磷酸酶变体 |
| EP1576166B1 (en) * | 2002-12-19 | 2014-10-15 | University Of Bristol | Novel method for the production of polyunsaturated fatty acids |
| CA2510561A1 (en) * | 2002-12-20 | 2004-07-15 | Basf Aktiengesellschaft | Malate dehydrogenase as a target for herbicides |
| EP2816117B1 (en) | 2004-09-29 | 2016-11-30 | Collplant Ltd. | Collagen producing plants and methods of generating and using same |
-
2005
- 2005-09-28 EP EP14185576.7A patent/EP2816117B1/en not_active Revoked
- 2005-09-28 EP EP16171177.5A patent/EP3088528B1/en active Active
- 2005-09-28 BR BRPI0516303-0A patent/BRPI0516303B1/pt active IP Right Grant
- 2005-09-28 KR KR1020077009817A patent/KR20070083870A/ko not_active Withdrawn
- 2005-09-28 WO PCT/IL2005/001045 patent/WO2006035442A2/en not_active Ceased
- 2005-09-28 EP EP17205280.5A patent/EP3312282B1/en not_active Expired - Lifetime
- 2005-09-28 EP EP05789469A patent/EP1809751B1/en not_active Revoked
- 2005-09-28 AT AT05789469T patent/ATE479762T1/de not_active IP Right Cessation
- 2005-09-28 EP EP10181115A patent/EP2360261A1/en not_active Ceased
- 2005-09-28 DE DE602005023332T patent/DE602005023332D1/de active Active
- 2005-09-28 CN CN2005800408217A patent/CN101065491B/zh not_active Expired - Lifetime
- 2005-09-28 MX MX2007003767A patent/MX2007003767A/es active IP Right Grant
- 2005-09-28 CA CA2582051A patent/CA2582051C/en active Active
- 2005-09-28 NZ NZ554787A patent/NZ554787A/en not_active IP Right Cessation
- 2005-09-28 EP EP10168971.9A patent/EP2357241B1/en not_active Revoked
- 2005-09-28 JP JP2007534176A patent/JP5100386B2/ja not_active Expired - Lifetime
-
2007
- 2007-03-29 IL IL182320A patent/IL182320A/en active IP Right Grant
- 2007-04-25 ZA ZA200703369A patent/ZA200703369B/xx unknown
-
2011
- 2011-11-29 JP JP2011259678A patent/JP5517309B2/ja not_active Expired - Fee Related
-
2018
- 2018-08-23 HK HK18110838.5A patent/HK1251611B/en not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0516303A (pt) | método de produção de colágeno em planta ou em célula de planta isolada, planta geneticamente modificada ou célula de planta isolada, sistema de planta, método de produção de colágeno fibirilar e construção de ácido nucléico | |
| DK2236601T3 (da) | Phytaser | |
| DK1838859T3 (da) | Transformeret plante, der udtrykker en mutansucrase og syntetiserer en modificeret stivelse | |
| ATE514781T1 (de) | Nukleinsäuresequenzen, die für proteine in zusammenhang mit abiotischer stressreaktion kodieren, sowie pflanzenzellen und pflanzen mit erhöhter umweltstressverträglichkeit | |
| AR050299A1 (es) | Plantas con una enzima fosforilante del almidon con una actividad aumentada en plástidos. | |
| WO2004090140A3 (en) | Methods and means for increasing the tolerance of plants to stress conditions | |
| WO2010028347A3 (en) | Continuous directed evolution of proteins and nucleic acids | |
| AR081191A2 (es) | Planta transgenica de maiz | |
| ATE426661T1 (de) | Somatische pluripotente zellen | |
| ZA200800517B (en) | Transplastomic plants expressing lumen-targeted protein | |
| AR048024A1 (es) | Plantas con actividad aumentada de distintas enzimas fosforilantes del almidon | |
| BR0011499A (pt) | Moléculas de ácido nucléico oriundas de plantas e células de,planta transgênicas de trigo e o seu uso para a produção de amido modificado | |
| PL387691A1 (pl) | Warianty oksydazy moczanowej i ich zastosowanie | |
| CL2008003469A1 (es) | Acido nucleico aislado de maiz asociado con la senalizacion de etileno en plantas; casete de expresion; celula huesped; proteina codificada; y metodo de modulacion de la respuesta de etileno en una planta. | |
| WO2003087313A3 (en) | Enhanced silk exsertion under stress | |
| DK1929001T3 (da) | Nye dehydrogenaser, disses derivater og en fremgangsmåde til fremstilling af optisk aktive alkanoler | |
| WO2004022782A3 (en) | Compositions and methods for tissue specific or inducible inhibition of gene expression | |
| WO2006056590A3 (en) | Plants having increased yield and a method for making the same | |
| WO2004090094A3 (de) | L-carnitin dehydrogenasen, deren derivate und ein verfahren zur herstellung von substituierten (s)-alkanolen | |
| WO2007069894A3 (en) | Constitutive plant promoters | |
| WO2003035881A3 (en) | Stress tolerant plants | |
| TR200100561T1 (tr) | Bitkilerin mantar ve bakteri direncinin artırılması yöntemi | |
| ATE423841T1 (de) | Verwendung von glutaminfreien medium | |
| WO2006081463A3 (en) | Thermococcus zilligii dna polymerases and variants thereof | |
| WO2003080844A3 (de) | Erhöhung des vitamin-e-gehalts in organismen durch erhöhung der 2-methyl-6-phytylhydrochinon-methyltransferase-aktivität |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 13/04/2021, OBSERVADAS AS CONDICOES LEGAIS. |