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BRPI0514296A - combinação de um inibidor seletivo da recaptação de noradrenalina e um inibidor da pdev - Google Patents

combinação de um inibidor seletivo da recaptação de noradrenalina e um inibidor da pdev

Info

Publication number
BRPI0514296A
BRPI0514296A BRPI0514296-2A BRPI0514296A BRPI0514296A BR PI0514296 A BRPI0514296 A BR PI0514296A BR PI0514296 A BRPI0514296 A BR PI0514296A BR PI0514296 A BRPI0514296 A BR PI0514296A
Authority
BR
Brazil
Prior art keywords
inhibitor
combination
norepinephrine reuptake
pdev
selective norepinephrine
Prior art date
Application number
BRPI0514296-2A
Other languages
English (en)
Inventor
Bernadette Hughes
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0417777A external-priority patent/GB0417777D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of BRPI0514296A publication Critical patent/BRPI0514296A/pt

Links

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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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Abstract

COMBINAçãO DE UM INIBIDOR SELETIVO DA RECAPTAçãO DE NORADRENALINA E UM INIBIDOR DA PDEV. A presente invenção refere-se a uma combinação de um inibidor seletivo da recaptação de noradrenalina (IRN) e um inibidor da fosfodiesterase tipo 5 (PDVE). Uma combinação deste tipo é particularmente útil no tratamento da dor.
BRPI0514296-2A 2004-08-10 2005-07-29 combinação de um inibidor seletivo da recaptação de noradrenalina e um inibidor da pdev BRPI0514296A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0417777A GB0417777D0 (en) 2004-08-10 2004-08-10 Pharmaceutical combination
US60630204P 2004-08-31 2004-08-31
PCT/IB2005/002457 WO2006016262A1 (en) 2004-08-10 2005-07-29 Combination of a selective noradrenaline reuptake inhibitor and a pdev inhibitor

Publications (1)

Publication Number Publication Date
BRPI0514296A true BRPI0514296A (pt) 2008-06-17

Family

ID=35044604

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0514296-2A BRPI0514296A (pt) 2004-08-10 2005-07-29 combinação de um inibidor seletivo da recaptação de noradrenalina e um inibidor da pdev

Country Status (12)

Country Link
US (1) US20090227562A1 (pt)
EP (1) EP1778241A1 (pt)
JP (1) JP2008509900A (pt)
KR (2) KR20080064911A (pt)
AU (1) AU2005270904A1 (pt)
BR (1) BRPI0514296A (pt)
CA (1) CA2575980A1 (pt)
IL (1) IL180557A0 (pt)
MX (1) MX2007000694A (pt)
NO (1) NO20066059L (pt)
RU (2) RU2349323C2 (pt)
WO (1) WO2006016262A1 (pt)

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US7598255B2 (en) 2005-08-04 2009-10-06 Janssen Pharmaceutica Nv Pyrimidine compounds as serotonin receptor modulators
JP2008273867A (ja) * 2007-04-27 2008-11-13 Asahi Kasei Pharma Kk 経粘膜投与用製剤
US8841300B2 (en) 2006-10-02 2014-09-23 Jerry M. Held Treatment for Parkinson's disease—combination high dose serotonergic synaptic reuptake inhibitor with phosphodiesterase inhibitor
EP2155182A2 (en) * 2007-05-18 2010-02-24 Vivus, Inc. Novel compositions comprising a phosphodiesterase-5 inhibitor and their use in methods of treatment
US20090131442A1 (en) * 2007-11-16 2009-05-21 Joseph Bernstein Method of Treating Bone Pain Caused by Osteoarthritis
US20130323288A1 (en) 2010-07-08 2013-12-05 Wellesley Pharmaceuticals, Llc Pharmaceutical formulation for bedwetting and method of use thereof
CN102018550B (zh) * 2010-12-01 2012-04-25 中国人民解放军第四军医大学 后纵韧带犁刀
EP2682128B1 (en) * 2011-02-28 2017-11-08 National Cerebral and Cardiovascular Center Atrial natriuretic peptide or brain natriuretic peptide for use in preventing metastasis
CA2888160A1 (en) * 2012-10-23 2014-05-01 Pfizer Inc. Use of a tetrasubstituted pyrazolo[4,3-d]pyrimidine compound for treating diabetic nephropathy
US9637470B2 (en) 2013-02-22 2017-05-02 Baylor College Of Medicine Treatment for substance use disorders and stress disorders
US10792326B2 (en) 2013-06-28 2020-10-06 Wellesley Pharmaceuticals, Llc Pharmaceutical formulation for bedwetting and method of use thereof
US20230398106A1 (en) * 2020-11-05 2023-12-14 Neurorive Inc Combination therapy of donepezil and sildenafil for the treatment of alzheimer's disease or cognitive impairment

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JP2008509900A (ja) 2008-04-03
EP1778241A1 (en) 2007-05-02
WO2006016262A1 (en) 2006-02-16
CA2575980A1 (en) 2006-02-16
AU2005270904A1 (en) 2006-02-16
RU2007102847A (ru) 2008-09-20
KR20070036171A (ko) 2007-04-02
KR20080064911A (ko) 2008-07-09
WO2006016262A8 (en) 2006-06-29
NO20066059L (no) 2007-01-29
IL180557A0 (en) 2008-03-20
RU2349323C2 (ru) 2009-03-20

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