[go: up one dir, main page]

BRPI0408834A - composições tópicas de l-carnitina - Google Patents

composições tópicas de l-carnitina

Info

Publication number
BRPI0408834A
BRPI0408834A BRPI0408834-4A BRPI0408834A BRPI0408834A BR PI0408834 A BRPI0408834 A BR PI0408834A BR PI0408834 A BRPI0408834 A BR PI0408834A BR PI0408834 A BRPI0408834 A BR PI0408834A
Authority
BR
Brazil
Prior art keywords
carnitine
skin
topical composition
acyl
range
Prior art date
Application number
BRPI0408834-4A
Other languages
English (en)
Inventor
Jacob Guth
Michael Fred Czuczak
Vickie Lentner
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of BRPI0408834A publication Critical patent/BRPI0408834A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"COMPOSIçõES TóPICAS DE L-CARNITINA". A presente invenção refere-se a uma composição tópica, que contém (a) L-carnitina, uma acil L-carnitina, um sal das mesmas, ou uma misturas das mesmas e (b) um ou mais hidróxi ácidos, enzimas proteolíticas, agentes clareadores da pele, ou uma mistura deles em um veículo farmacologicamente aceitável para aplicação tópica. A composição tópica pode ser administrada para melhorar ou prevenir condições prejudiciais da pele (como por exemplo, esfoliação epidérmica e perda de elasticidade da pele), esfoliar a pele, acelerar a renovação da pele, e/ou clarear a pele. Ela pode, por exemplo, ser administrada para minimizar a formação de cicatrizes devido a infecção por varicela, secagem e descamação devido à queimadura solar e melhorar a elasticidade da pele. A composição tópica tem preferencialmente um pH situando-se na faixa de cerca de 3,5 a cerca de 8. De acordo com uma modalidade, o pH da composição tópica situa-se na faixa de 3,5 a cerca de 6,5 ou 7. De acordo com outra modalidade, o pH da composição tópica situa-se na faixa de cerca de 6 a cerca de 8 e preferencialmente de cerca de 6,5 a 7,5. De acordo com uma modalidade preferida, a composição tópica é preferencialmente substancialmente livre de D-carnitina, acil D-carnitina e seus sais e, mais preferencialmente, é além disso substancialmente livre de LD-carnitina, acil LD-carnitina e seus sais.
BRPI0408834-4A 2003-03-28 2004-03-29 composições tópicas de l-carnitina BRPI0408834A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45882203P 2003-03-28 2003-03-28
PCT/US2004/009591 WO2004087072A2 (en) 2003-03-28 2004-03-29 Topical l-carnitine compositions

Publications (1)

Publication Number Publication Date
BRPI0408834A true BRPI0408834A (pt) 2006-04-04

Family

ID=33131830

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408834-4A BRPI0408834A (pt) 2003-03-28 2004-03-29 composições tópicas de l-carnitina

Country Status (13)

Country Link
US (1) US20050100519A1 (pt)
EP (1) EP1610760A4 (pt)
JP (1) JP2006522807A (pt)
KR (1) KR20050113669A (pt)
CN (1) CN1964695A (pt)
AU (1) AU2004226324A1 (pt)
BR (1) BRPI0408834A (pt)
CA (1) CA2519998A1 (pt)
EA (1) EA200501413A1 (pt)
MX (1) MXPA05010417A (pt)
NO (1) NO20054465L (pt)
WO (1) WO2004087072A2 (pt)
ZA (1) ZA200507824B (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7416869B2 (en) * 2004-08-19 2008-08-26 Lonza Ltd. Enzyme delivery systems, application in water based products
ITMI20041603A1 (it) * 2004-08-04 2004-11-04 Vama Farmacosmetica S R L Materia prima cosmetica a base di 1-carnitina per preparato ad effetto idratante di lunga durata e preparato cosmetico ottenuto con questa materia prima
EP1649846A1 (de) * 2004-10-21 2006-04-26 Neubourg Skin Care GmbH & Co. KG Verwendung von Harnstoff zur Behandlung von Altersflecken
KR101165848B1 (ko) * 2005-08-18 2012-07-13 (주)아모레퍼시픽 효소 및 아미노산을 함유하는 피부 화장료 조성물
UA99101C2 (ru) 2006-05-19 2012-07-25 Мэри Кей, Инк. Композиция для местного ухода за кожей, содержащая соединения глицерина ди- и моносалицилата
TW200831125A (en) * 2006-12-08 2008-08-01 Pola Chem Ind Inc A discrimination method of skin barrier function, the screening method of skin barrier function reinforced material by using the discrimination method, the skin barrier function reinforced materials, and the cosmetic material containing the skin barrier
AU2007353211B2 (en) * 2007-05-11 2013-08-29 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Gel useful for the delivery of cosmetic active ingredients
MX2011004666A (es) * 2008-11-11 2011-05-31 Sigma Tau Ind Farmaceuti Compuesto util para tratar celulitis.
KR101017586B1 (ko) * 2008-11-28 2011-02-28 (주)아모레퍼시픽 피부 미백용 화장료 조성물
FR2949969B1 (fr) * 2009-09-11 2012-08-03 Svr Lab Composition cosmetique a base d'uree pure, utilisation et procede d'application correspondant
DE102012214038A1 (de) * 2012-08-08 2014-02-13 Beiersdorf Ag Verwendung von Wirkstoffkombinationen aus Harnstoff und Car-ni-tin und/oder einem oder mehreren Acyl-Carnitinen zur Behandlung und Prophylaxe von Neurodermitis sowie des diabetischen Fußes
WO2014164806A1 (en) 2013-03-12 2014-10-09 Mary Kay Inc. Preservative system
US20150342853A1 (en) * 2014-06-02 2015-12-03 Avon Products, Inc. Topical Lightening Composition and Methods of Use Thereof
EP3182959B1 (en) * 2014-08-18 2020-06-10 Pan-Montojo, Francisco Glycolic acid enhances sperm mobility
ES2910653T3 (es) * 2015-01-27 2022-05-13 Professional Dietetics S P A In Forma Abbreviata P D S P A Composiciones que comprenden a) quitosano, b) ácido glicólico, c) carnitina y/o n-acetilcisteína para el tratamiento de descamación dermoepidérmica
CN114788791A (zh) 2017-06-23 2022-07-26 宝洁公司 用于改善皮肤外观的组合物和方法
KR101934022B1 (ko) * 2017-12-04 2018-12-31 주식회사 엘지생활건강 피부 각질 박리 촉진용 화장용 조성물
CN112437657A (zh) 2018-07-03 2021-03-02 宝洁公司 处理皮肤状况的方法
KR102253135B1 (ko) * 2018-07-17 2021-05-17 주식회사 엘지생활건강 각질 박리 증진용 화장료 조성물
CN119157765A (zh) * 2018-07-17 2024-12-20 株式会社Lg生活健康 组合物在制造化妆品中的应用以及增强角质剥离的方法
KR102771004B1 (ko) * 2018-10-17 2025-02-21 주식회사 엘지생활건강 피부 각질 박리 촉진용 화장료 조성물
CN109528628B (zh) * 2018-12-14 2022-02-08 北京中医药大学 一种包含左卡尼汀的药用组合物及其制备方法和用途
JP7590462B2 (ja) 2020-06-01 2024-11-26 ザ プロクター アンド ギャンブル カンパニー ビタミンｂ３化合物の皮膚への浸透を改善する方法
US10959933B1 (en) 2020-06-01 2021-03-30 The Procter & Gamble Company Low pH skin care composition and methods of using the same
WO2022191602A1 (ko) * 2021-03-08 2022-09-15 주식회사 엘지생활건강 카르니틴살리실레이트를 유효성분으로 포함하는 화장료 조성물
WO2025258571A1 (ja) * 2024-06-12 2025-12-18 大阪ガスケミカル株式会社 ターンオーバー促進剤およびその用途

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3683939A (en) * 1970-05-28 1972-08-15 Wilson Pharm & Chem Corp Proteinaceous cosmetic material for hair conditioning
JPS51148042A (en) * 1975-06-14 1976-12-18 Kanebo Ltd Skin toiletry
US5389677B1 (en) * 1986-12-23 1997-07-15 Tristrata Inc Method of treating wrinkles using glycalic acid
JPH0615462B2 (ja) * 1989-01-12 1994-03-02 レイコ 小阪 毛髪用組成物
IT1261984B (it) * 1993-06-22 1996-06-11 Avantgarde Spa Uso di esteri della l-carnitina o di acil l- carnitine con idrossiacidi per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee.
JPH07157409A (ja) * 1993-12-07 1995-06-20 Kobe Steel Ltd 美白性化粧料
IT1272290B (it) * 1994-06-20 1997-06-16 Avantgarde Spa Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee
JP3229517B2 (ja) * 1995-04-18 2001-11-19 カネボウ株式会社 美白化粧料
JPH09263514A (ja) * 1996-03-29 1997-10-07 Shiseido Co Ltd 皮膚外用剤
US5968528A (en) * 1997-05-23 1999-10-19 The Procter & Gamble Company Skin care compositions
JPH1129457A (ja) * 1997-07-04 1999-02-02 Kanebo Ltd 皮膚化粧料
JPH11180851A (ja) * 1997-12-22 1999-07-06 Kanebo Ltd 皮膚化粧料
DE19806946A1 (de) * 1998-02-19 1999-09-09 Beiersdorf Ag Kosmetische oder dermatologische Wirkstoffkombinationen aus mindestens einer Substanz gewählt aus der Gruppe, bestehend aus Carnitin und den Acylcarnitinen, und mindestens einem Retinoid sowie Zubereitungen mit einem Gehalt an solchen Wirkstoffkombinationen
DE19806947A1 (de) * 1998-02-19 1999-08-26 Beiersdorf Ag Kosmetische oder dermatologische Wirkstoffkombinationen aus mindestens einer Substanz gewählt aus der Gruppe, bestehend aus Carnitin und den Acylcarnitinen, und mindestens einem Chinon und oder mindestens einem Hydrochinon sowie Zubereitungen mit einem Gehalt an solchen Wirkstoffkombinationen
US6149924A (en) * 1998-07-20 2000-11-21 Biomed Research & Technologies, Inc. Composition for enhancing lipid production, barrier function, hydrogen peroxide neutralization, and moisturization of the skin
JP3229594B2 (ja) * 1998-12-16 2001-11-19 カネボウ株式会社 美白化粧料
JP3874966B2 (ja) * 1999-05-11 2007-01-31 株式会社カネボウ化粧品 シート状美白パック化粧料
US6416769B1 (en) * 2000-03-03 2002-07-09 Australian Importers, Ltd. Cosmetic compositions comprising exfoliating enzymes and uses thereof
WO2001082878A1 (en) * 2000-05-02 2001-11-08 Perricone Nicholas V Treatment of skin damage using acetyl carnitine and phosphatidylcholine and/or ascorbyl fatty acid esters
DE10129504A1 (de) * 2001-06-19 2003-01-09 Beiersdorf Ag Verwendung von Carnitin und/oder einem oder mehreren Acyl-Carnitinen zur Herstellung von kosmetischen oder dermatologischen Zubereitungen zur Behandlung und/oder Prophylaxe von Pigmentierungsstörungen
JP2005513007A (ja) * 2001-11-13 2005-05-12 ザ プロクター アンド ギャンブル カンパニー 特定の浸透圧保護剤によって安定化させた酵素を含有する組成物、及びパーソナルケアにおける前記組成物の使用方法

Also Published As

Publication number Publication date
WO2004087072A2 (en) 2004-10-14
CA2519998A1 (en) 2004-10-14
AU2004226324A1 (en) 2004-10-14
KR20050113669A (ko) 2005-12-02
US20050100519A1 (en) 2005-05-12
CN1964695A (zh) 2007-05-16
NO20054465L (no) 2005-12-12
EP1610760A4 (en) 2008-01-09
NO20054465D0 (no) 2005-09-27
EP1610760A2 (en) 2006-01-04
WO2004087072A3 (en) 2006-04-27
MXPA05010417A (es) 2005-11-04
JP2006522807A (ja) 2006-10-05
EA200501413A1 (ru) 2006-10-27
ZA200507824B (en) 2007-04-25

Similar Documents

Publication Publication Date Title
BRPI0408834A (pt) composições tópicas de l-carnitina
BRPI0214794B8 (pt) sistema para melhorar a saúde da pele de usuários de artigo absorvente.
BRPI0514420A (pt) peptìdeo, variante do mesmo, ou um sal farmaceuticamente aceitável do mesmo, composição, uso de um peptìdeo ou de uma variante de peptìdeo, substrato, e, métodos de tratamento ou prevenção de um infecção microbiana, e de tratamento de uma ferida em um indivìduo
BR9916642A (pt) Método e composição de substrato para uso no isolamento de irritantes cutâneos
BR9802557A (pt) Composição de pele tópica, e, processo para reduzir a aparência visual de uma ruga e/ou traço fino.
BR9811923A (pt) Compostos possuindo atividade neuronal
BR0213612A (pt) Composto, composição farmacêutica, uso do composto e método para tratamento de doença ou condição
BR9306564A (pt) Processo para o tratamento da epiderme de um mamífero terrestre sofrendo de uma condição constitída por uma função de barreira epidérmica perturbada
BRPI0411319A (pt) compostos terapeuticamente ativos e sua utilização
BRPI0409624A (pt) 2-hidróxi-3-diaminoalcanos de benzamida
BR9914419A (pt) Terapia para melhoria da percepção
BR0308206A (pt) Composição oral sinergìstica com composto volátil de enxofre para o controle de odor para hálito, e, método para neutralizar sinergisticamente o odor de hálito de composto volátil de enxofre
BR0007404A (pt) Composições de soja para despigmentação e cuidado com a pele
ATE311844T1 (de) Nicht-irritierende zusammensetzung zur behandlung des aknes und andere hautzustände
BR0312165A (pt) Utilização da taurina para o tratamento da alopecia
BR0313630A (pt) Composição para aplicação tópica, sistema para o tratamento de caspa, métodos para o tratamento e/ou prevenção da caspa e da coceira do couro cabeludo e usos de uma combinação sinérgica
BR9914023A (pt) Composição de esfregão e de máscara da pele de tratamento pessoal e processo para umedecimento da pele
BR0112337A (pt) Derivados de fosfolipìdeos de ácido valpróico e suas misturas
BR0317395A (pt) Sìlica estruturalmente modificada
BR0207703A (pt) Composições viricidas
BRPI0410358A (pt) tratamento tópico de condições da pele
BR9812660A (pt) Composições e métodos para tratar distúrbios respiratórios
BR0311154A (pt) Composição para melhorar o melasma e composição para reduzir a opacidade da pele
BR9712141A (pt) Aplicação de 1-hifróxi-2-piridonas para tratamento de infecções cutâneas.
BR9906998A (pt) Método e composições para reduzir o envelhecimento dermatológico e para reduzir contusões

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B15K Others concerning applications: alteration of classification

Ipc: A61K 8/44 (2006.01), A61K 8/365 (2006.01), A61K 8/

B11T Dismissal of application maintained [chapter 11.20 patent gazette]