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BR9915969A - Toxinas pesticidas e seq ências de nucleotìdeos que codificam estas toxinas - Google Patents

Toxinas pesticidas e seq ências de nucleotìdeos que codificam estas toxinas

Info

Publication number
BR9915969A
BR9915969A BR9915969-4A BR9915969A BR9915969A BR 9915969 A BR9915969 A BR 9915969A BR 9915969 A BR9915969 A BR 9915969A BR 9915969 A BR9915969 A BR 9915969A
Authority
BR
Brazil
Prior art keywords
toxins
nucleotide sequences
genes
sequences encoding
pesticide
Prior art date
Application number
BR9915969-4A
Other languages
English (en)
Other versions
BR9915969B1 (pt
Inventor
Jerald S Feitelson
H Ernest Schnepf
Kenneth E Narva
Brian A Stockhoff
James Schmeits
David Loewer
Charles Joseph Dullum
Judy Muller-Cohn
Lisa Stamp
George Morrill
Stacey Finstad-Lee
Original Assignee
Mycogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mycogen Corp filed Critical Mycogen Corp
Publication of BR9915969A publication Critical patent/BR9915969A/pt
Publication of BR9915969B1 publication Critical patent/BR9915969B1/pt

Links

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50Isolated enzymes; Isolated proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/142Toxicological screening, e.g. expression profiles which identify toxicity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Insects & Arthropods (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Agronomy & Crop Science (AREA)
  • Cell Biology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

Patente de Invenção: <B>"TOXINAS PESTICIDAS E SEQ êNCIAS DE NUCLEOTìDEOS QUE CODIFICAM ESTAS TOXINAS"<D>. Revelados e reivindicados são novos isolados de Bacillus thuringiensis, toxinas pesticidas, genes e iniciadores e sondas de nucleotídeo para a identificação de genes que codificam toxinas ativas contra pestes. Os iniciadores são úteis em técnicas de PCR para produzir fragmentos de gene que são característicos de genes que codificam estas toxinas. A presente invenção provê totalmente novas famílias de toxinas que podem ser obtidas a partir de sobrenadantes de culturas de Bacillus.
BRPI9915969-4A 1998-05-06 1999-05-06 "hospedeiro recombinante e método para controlar uma peste lepidopterana". BR9915969B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/073,898 US6242669B1 (en) 1996-10-30 1998-05-06 Pesticidal toxins and nucleotide sequences which encode these toxins
US09/073,898 1998-05-06
PCT/US1999/009997 WO1999057282A2 (en) 1998-05-06 1999-05-06 Pesticidal toxins and nucleotide sequences which encode these toxins

Publications (2)

Publication Number Publication Date
BR9915969A true BR9915969A (pt) 2001-08-28
BR9915969B1 BR9915969B1 (pt) 2014-10-14

Family

ID=22116467

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9915969-4A BR9915969B1 (pt) 1998-05-06 1999-05-06 "hospedeiro recombinante e método para controlar uma peste lepidopterana".

Country Status (16)

Country Link
US (2) US6242669B1 (pt)
EP (2) EP1944372B1 (pt)
JP (1) JP2002513574A (pt)
KR (1) KR100763074B1 (pt)
CN (1) CN1296482C (pt)
AR (1) AR016989A1 (pt)
AT (1) ATE556138T1 (pt)
AU (1) AU759579B2 (pt)
BR (1) BR9915969B1 (pt)
CA (1) CA2327266C (pt)
DK (1) DK1944372T3 (pt)
ES (1) ES2383997T3 (pt)
HU (1) HUP0101991A3 (pt)
MX (1) MXPA00010890A (pt)
TR (1) TR200003264T2 (pt)
WO (1) WO1999057282A2 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR020141A1 (es) 1998-08-10 2002-04-10 Mycogen Corp Toxinas y genes pesticidas de cepas de bacillus laterosporus
US7700838B1 (en) * 1999-09-17 2010-04-20 Monsanto Technology Llc Bacillus thuringiensis chromosomal genome sequences and uses thereof
CN100529080C (zh) * 2000-05-18 2009-08-19 拜尔生物科学公司 细菌杀昆虫蛋白
US7091399B2 (en) * 2000-05-18 2006-08-15 Bayer Bioscience N.V. Transgenic plants expressing insecticidal proteins and methods of producing the same
US6706860B2 (en) 2000-05-18 2004-03-16 Bayer Bioscience N.V. Toxins
CN101385467B (zh) * 2001-03-30 2014-11-05 辛根塔参与股份公司 新的杀虫毒素
AR035799A1 (es) * 2001-03-30 2004-07-14 Syngenta Participations Ag Toxinas insecticidas aisladas de bacillus thuringiensis y sus usos.
EP1499176B1 (en) 2002-03-06 2010-04-28 Syngenta Participations AG Novel Vip3 toxins and methods of use
DE60332711D1 (de) 2002-03-22 2010-07-08 Bayer Bioscience Nv Neue insektizide proteine von bazillus thuringiensis
ES2311731T3 (es) 2002-06-28 2009-02-16 Dow Agrosciences Llc Proteinas de accion pesticida y polinucleotidos que se pueden obtener a partir de especies de paenibacillus.
CN100420752C (zh) * 2006-03-10 2008-09-24 浙江大学 一种杀虫基因及其用途
KR20130020849A (ko) 2006-06-03 2013-02-28 신젠타 파티서페이션즈 아게 옥수수 이벤트 mir162
UA111592C2 (uk) 2010-07-07 2016-05-25 Сінгента Партісіпейшнс Аг Спосіб контролю над твердокрилими комахами-шкідниками
WO2013015993A1 (en) 2011-07-28 2013-01-31 Syngenta Participations Ag Methods and compositions for controlling nematode pests
ES2670505T3 (es) 2012-02-16 2018-05-30 Syngenta Participations Ag Proteínas pesticidas modificadas
NZ726117A (en) 2014-06-20 2017-10-27 Dow Agrosciences Llc Vegetative insecticidal proteins useful for control of insect pests
US10743535B2 (en) 2017-08-18 2020-08-18 H&K Solutions Llc Insecticide for flight-capable pests
WO2020055885A1 (en) * 2018-09-11 2020-03-19 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
CN110903361B (zh) * 2019-12-24 2021-08-06 隆平生物技术(海南)有限公司 一种植物抗虫基因mVip3Aa及其载体和应用

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4467036A (en) 1981-11-12 1984-08-21 The Board Of Regents Of The University Of Washington Bacillus thuringiensis crystal protein in Escherichia coli
US4448885A (en) 1981-04-27 1984-05-15 Board Of The Regents Of The University Of Washington Bacillus thuringiensis crystal protein in Escherichia coli
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
US5380831A (en) 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
US4695462A (en) 1985-06-28 1987-09-22 Mycogen Corporation Cellular encapsulation of biological pesticides
US4695455A (en) 1985-01-22 1987-09-22 Mycogen Corporation Cellular encapsulation of pesticides produced by expression of heterologous genes
US4797276A (en) 1985-03-22 1989-01-10 Mycogen Corporation Control of cotton boll weevil, alfalfa weevil, and corn rootworm via contact with a strain of Bacillus thuringiensis
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4918006A (en) 1985-07-01 1990-04-17 E. I. Du Pont De Nemours And Company Gene coding for insecticidal crystal protein
US4853331A (en) 1985-08-16 1989-08-01 Mycogen Corporation Cloning and expression of Bacillus thuringiensis toxin gene toxic to beetles of the order Coleoptera
CA1341092C (en) 1985-12-12 2000-09-05 David L. Edwards Process for altering the host range of bacillus thuringiensis toxins, and novel toxins produced thereby
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US4948734A (en) 1987-08-12 1990-08-14 Mycogen Corporation Novel isolates of bacillus thuringiensis having activity against nematodes
US5151363A (en) 1990-07-27 1992-09-29 Mycogen Corporation Isolates of Bacillus thuringiensis that are active against nematodes
US5322932A (en) 1987-08-12 1994-06-21 Mycogen Corporation Nematode-active toxin from a Bacillus thuringiensis isolate
US5236843A (en) 1987-08-12 1993-08-17 Mycogen Corporation Gene encoding a nematode-active toxin cloned from a Bacillus thuringiensis isolate
US5439881A (en) 1987-08-12 1995-08-08 Mycogen Corporation Gene encoding nematode-active toxin PS63B cloned from Bacillus thuringiensis isolate
US5093120A (en) 1987-08-12 1992-03-03 Mycogen Corporation Novel isolates of Bacillus thuringiensis having activity against nematodes
US5281530A (en) 1987-08-12 1994-01-25 Mycogen Corporation Genes encoding nematode-active toxins cloned from bacillus thuringiensis isolate PS17
US5262399A (en) 1987-08-12 1993-11-16 Mycogen Corporation Compositions and methods for the control of flukes
NZ230375A (en) 1988-09-09 1991-07-26 Lubrizol Genetics Inc Synthetic gene encoding b. thuringiensis insecticidal protein
US4990332A (en) 1988-10-25 1991-02-05 Mycogen Corporation Novel lepidopteran-active Bacillus thuringiensis isolate
US5039523A (en) 1988-10-27 1991-08-13 Mycogen Corporation Novel Bacillus thuringiensis isolate denoted B.t. PS81F, active against lepidopteran pests, and a gene encoding a lepidopteran-active toxin
US5169629A (en) 1988-11-01 1992-12-08 Mycogen Corporation Process of controlling lepidopteran pests, using bacillus thuringiensis isolate denoted b.t ps81gg
US5135867A (en) 1988-11-01 1992-08-04 Mycogen Corporation Gene encoding a lepidopteran-active toxin from Bacillus thuringiensis isolate denoted B.t. .PS81GG active against lepidopteran pests
US5164180A (en) 1989-05-18 1992-11-17 Mycogen Corporation Bacillus thuringiensis isolates active against lepidopteran pests
US5126133A (en) 1989-06-27 1992-06-30 Mycogen Corporation Bacillus thuringiensis isolate active against lepidopteran pests, and genes encoding novel lepidopteran-active toxins
US5204237A (en) 1989-10-25 1993-04-20 Mycogen Corporation Universal and specific probes for Bacillus thuringiensis endotoxin genes
US5270448A (en) 1990-07-27 1993-12-14 Mycogen Corporation Isolates of Bacillus thuringiensis that are active against nematodes
US5686069A (en) 1990-10-15 1997-11-11 Mycogen Corporation Protein toxins active against lepidopteran pests
WO1993016094A2 (en) 1992-02-12 1993-08-19 Chromagen, Inc. Applications of fluorescent n-nucleosides and fluorescent structural analogs of n-nucleosides
US5262159A (en) 1992-08-24 1993-11-16 Mycogen Corporation Use of Bacillus thuringiensis isolates for controlling pests in the family aphididae
JP3435159B2 (ja) 1992-08-27 2003-08-11 プラント・ジェネティック・システムズ・エヌ・ブイ バチルス・チュリンゲンシスの新菌株及び殺虫作用をもつそのタンパク質
US5849870A (en) 1993-03-25 1998-12-15 Novartis Finance Corporation Pesticidal proteins and strains
BR9406484A (pt) 1993-03-25 1996-01-09 Ciba Geigy Ag Novas proteinas e cepas pesticidas
US5877012A (en) 1993-03-25 1999-03-02 Novartis Finance Corporation Class of proteins for the control of plant pests
HU226143B1 (en) 1993-04-09 2008-05-28 Plant Genetic Systems Nv New bacillus thuringiensis strains and their insecticidal proteins
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5667993A (en) 1995-10-06 1997-09-16 Mycogen Corporation Primers and probes for the identification of bacillus thuringiensis genes and isolates
US5670365A (en) 1995-10-06 1997-09-23 Mycogen Corporation Identification of, and uses for, nematicidal bacillus thuringiensis genes, toxins, and isolates
JP2001507208A (ja) * 1996-07-01 2001-06-05 マイコーゲン コーポレーション 害虫に対して有効な毒素
EP0938562A2 (en) 1996-10-30 1999-09-01 Mycogen Corporation Pesticidal toxins and nucleotide sequences which encode these toxins
US7129212B2 (en) * 1996-10-30 2006-10-31 Mycogen Corporation Polynucleotides, pesticidal proteins, and novel methods of using them
CN1256712A (zh) 1997-04-03 2000-06-14 诺瓦提斯公司 植物病害控制

Also Published As

Publication number Publication date
BR9915969B1 (pt) 2014-10-14
DK1944372T3 (da) 2012-06-04
EP1944372B1 (en) 2012-05-02
CN1296482C (zh) 2007-01-24
EP1944372A3 (en) 2010-06-02
MXPA00010890A (es) 2002-04-24
AU759579B2 (en) 2003-04-17
CN1307639A (zh) 2001-08-08
EP1075522A2 (en) 2001-02-14
JP2002513574A (ja) 2002-05-14
WO1999057282A3 (en) 2000-06-22
KR20010043334A (ko) 2001-05-25
HUP0101991A3 (en) 2003-03-28
TR200003264T2 (tr) 2001-02-21
AU3888399A (en) 1999-11-23
CA2327266A1 (en) 1999-11-11
CA2327266C (en) 2010-01-12
ATE556138T1 (de) 2012-05-15
WO1999057282A2 (en) 1999-11-11
US6242669B1 (en) 2001-06-05
AR016989A1 (es) 2001-08-01
EP1944372A2 (en) 2008-07-16
HUP0101991A2 (hu) 2001-10-28
KR100763074B1 (ko) 2007-10-04
ES2383997T3 (es) 2012-06-28
US20020100080A1 (en) 2002-07-25
US6656908B2 (en) 2003-12-02

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 10 (IX), 8O, 13 E 25 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 14/10/2014, OBSERVADAS AS CONDICOES LEGAIS.