BR9912519A - Stabilized variants of streptomyces subtilisin inhibitor - Google Patents
Stabilized variants of streptomyces subtilisin inhibitorInfo
- Publication number
- BR9912519A BR9912519A BR9912519-6A BR9912519A BR9912519A BR 9912519 A BR9912519 A BR 9912519A BR 9912519 A BR9912519 A BR 9912519A BR 9912519 A BR9912519 A BR 9912519A
- Authority
- BR
- Brazil
- Prior art keywords
- variants
- subtilisin inhibitor
- streptomyces subtilisin
- compositions
- ssi
- Prior art date
Links
- 108700018667 Streptomyces subtilisin inhibitor Proteins 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 abstract 6
- 101710151905 Subtilisin inhibitor Proteins 0.000 abstract 3
- 238000004140 cleaning Methods 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000002797 proteolythic effect Effects 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/26—Organic compounds containing nitrogen
- C11D3/33—Amino carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/37—Polymers
- C11D3/3703—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C11D3/3719—Polyamides or polyimides
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38618—Protease or amylase in liquid compositions only
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Enzymes And Modification Thereof (AREA)
- Detergent Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cosmetics (AREA)
- Peptides Or Proteins (AREA)
Abstract
Patente de Invenção: <B>"VARIANTES ESTABILIZADAS DE INIBIDOR DE SUBTILISINA DE STREPTOMYCES"<D>. A presente invenção refere-se a variantes de inibidor de subtilisina de Streptomyces (SSI) e àqueles inibidores que têm homologia com SSI. Tais variantes são úteis em associação com enzimas, particularmente com proteases, em composições para limpeza e em composições para higiene pessoal. As variantes compreendem uma substituição de aminoácido na posição 63 correspondente a SSI. Tais variantes fornecem maior estabilidade proteolítica em composições para limpeza e em composições para higiene pessoal. A presente invenção também refere-se a composições para limpeza e a composições para higiene pessoal que compreendem as presentes variantes, assim como a genes que codificam as variantes.Invention Patent: <B> "STABILIZED VARIABLES OF STREPTOMYCES SUBTILISIN INHIBITOR" <D>. The present invention relates to Streptomyces subtilisin inhibitor (SSI) variants and to those inhibitors that have homology to SSI. Such variants are useful in association with enzymes, particularly with proteases, in cleaning compositions and in personal hygiene compositions. The variants comprise an amino acid substitution at position 63 corresponding to SSI. Such variants provide greater proteolytic stability in cleaning compositions and in personal hygiene compositions. The present invention also relates to cleaning compositions and personal hygiene compositions that comprise the present variants, as well as to genes encoding the variants.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9191198P | 1998-06-26 | 1998-06-26 | |
| PCT/US1999/015246 WO2000001826A2 (en) | 1998-06-26 | 1999-07-07 | Stabilized variants of streptomyces subtilisin inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9912519A true BR9912519A (en) | 2001-05-02 |
Family
ID=22230265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9912519-6A BR9912519A (en) | 1998-06-26 | 1999-07-07 | Stabilized variants of streptomyces subtilisin inhibitor |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1093518A2 (en) |
| JP (1) | JP2004500007A (en) |
| CN (1) | CN1316000A (en) |
| AR (1) | AR020106A1 (en) |
| AU (1) | AU4862399A (en) |
| BR (1) | BR9912519A (en) |
| CA (1) | CA2332564A1 (en) |
| WO (1) | WO2000001826A2 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE50107849D1 (en) | 2000-07-28 | 2005-12-01 | Henkel Kgaa | NEW AMYLOLYTIC ENZYME FROM BACILLUS SP. A 7-7 (DSM 12368) AND WASHING AND CLEANING AGENT WITH THIS NEW AMYLOLYTIC ENZYME |
| DE50113038D1 (en) | 2000-11-28 | 2007-10-31 | Henkel Kgaa | CYCLODEXTRINE -GLUCANOTRANSFERASE (CG TASE) FROM BACILLUS AGARADHERENS (DSM 9948) AND WASHING AND CLEANING AGENT WITH THIS NEW CYCLODEXTRIN GLUCANOTRANSFERASE |
| JP2005513007A (en) * | 2001-11-13 | 2005-05-12 | ザ プロクター アンド ギャンブル カンパニー | Compositions containing enzymes stabilized by specific osmoprotectants and methods of using said compositions in personal care |
| CN1612723A (en) * | 2001-11-13 | 2005-05-04 | 宝洁公司 | Local compositions containing enzymes stabilized with inhibitors |
| DE10162728A1 (en) | 2001-12-20 | 2003-07-10 | Henkel Kgaa | New alkaline protease from Bacillus gibsonii (DSM 14393) and washing and cleaning agents containing this new alkaline protease |
| DE10162727A1 (en) | 2001-12-20 | 2003-07-10 | Henkel Kgaa | New alkaline protease from Bacillus gibsonii (DSM 14391) and washing and cleaning agents containing this new alkaline protease |
| DE10163884A1 (en) | 2001-12-22 | 2003-07-10 | Henkel Kgaa | New alkaline protease from Bacillus sp. (DSM 14392) and detergents and cleaning agents containing this new alkaline protease |
| DE10360805A1 (en) | 2003-12-23 | 2005-07-28 | Henkel Kgaa | New alkaline protease and detergents containing this novel alkaline protease |
| EP2076591A2 (en) | 2006-10-20 | 2009-07-08 | Danisco US, INC., Genencor Division | Polyol oxidases |
| DE102007032111B4 (en) | 2007-07-09 | 2017-07-20 | Henkel Ag & Co. Kgaa | New proteases and detergents and cleaning agents containing these proteases |
| DE102007036756A1 (en) | 2007-08-03 | 2009-02-05 | Henkel Ag & Co. Kgaa | New proteases and detergents and cleaners containing these new proteases |
| CN103842378B (en) * | 2011-10-12 | 2018-01-02 | 三洋化成工业株式会社 | Protein protease inhibitor and protein solution and detergent composition containing same |
| DE102022205593A1 (en) * | 2022-06-01 | 2023-12-07 | Henkel Ag & Co. Kgaa | DETERGENT AND CLEANING AGENTS WITH IMPROVED ENZYME STABILITY |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE242270T1 (en) * | 1996-09-24 | 2003-06-15 | Procter & Gamble | STABILIZED PROTEINS WITH PROTEASE INHIBITOR FUNCTION AND VARIANTS THEREOF |
-
1999
- 1999-07-07 AU AU48623/99A patent/AU4862399A/en not_active Abandoned
- 1999-07-07 EP EP99932287A patent/EP1093518A2/en not_active Withdrawn
- 1999-07-07 BR BR9912519-6A patent/BR9912519A/en not_active IP Right Cessation
- 1999-07-07 CN CN 99810458 patent/CN1316000A/en active Pending
- 1999-07-07 JP JP2000558216A patent/JP2004500007A/en active Pending
- 1999-07-07 WO PCT/US1999/015246 patent/WO2000001826A2/en not_active Ceased
- 1999-07-07 AR ARP990103288 patent/AR020106A1/en not_active Application Discontinuation
- 1999-07-07 CA CA002332564A patent/CA2332564A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU4862399A (en) | 2000-01-24 |
| EP1093518A2 (en) | 2001-04-25 |
| CA2332564A1 (en) | 2000-01-13 |
| CN1316000A (en) | 2001-10-03 |
| WO2000001826A2 (en) | 2000-01-13 |
| WO2000001826A3 (en) | 2000-04-06 |
| JP2004500007A (en) | 2004-01-08 |
| AR020106A1 (en) | 2002-04-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES |
|
| B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007. |