BR9908381A - Fragmento de ácido nucléico isolado, gene quimérico, célula hospedeira transformada, polipetìdio, processo de alteração do nìvel de expressão de uma enzima, método de produção de um ácido graxo dessaturado, semente, óleo, método de produção de óleo de semente, método de obtenção de um fragmento de ácido nucléico e produto - Google Patents
Fragmento de ácido nucléico isolado, gene quimérico, célula hospedeira transformada, polipetìdio, processo de alteração do nìvel de expressão de uma enzima, método de produção de um ácido graxo dessaturado, semente, óleo, método de produção de óleo de semente, método de obtenção de um fragmento de ácido nucléico e produtoInfo
- Publication number
- BR9908381A BR9908381A BR9908381-7A BR9908381A BR9908381A BR 9908381 A BR9908381 A BR 9908381A BR 9908381 A BR9908381 A BR 9908381A BR 9908381 A BR9908381 A BR 9908381A
- Authority
- BR
- Brazil
- Prior art keywords
- nucleic acid
- fragment
- oil
- producing
- detected
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 14
- 108090000790 Enzymes Proteins 0.000 title abstract 5
- 102000004190 Enzymes Human genes 0.000 title abstract 5
- 150000007523 nucleic acids Chemical group 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 239000012634 fragment Substances 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 title 1
- 229930195729 fatty acid Natural products 0.000 title 1
- 239000000194 fatty acid Substances 0.000 title 1
- 150000004665 fatty acids Chemical class 0.000 title 1
- 235000019198 oils Nutrition 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- -1 seed Substances 0.000 title 1
- 235000015112 vegetable and seed oil Nutrition 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 abstract 3
- 150000002632 lipids Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 1
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Fats And Perfumes (AREA)
Abstract
"FRAGMENTO DE áCIDO-NUCLéICO ISOLADO, GENE QUIMéRICO, CéLULA HOSPEDEIRA TRANSFORMADA, POLIPETìDIO, PROCESSO DE ALTERAçãO DO NìVEL DE EXPRESSãO DE UMA ENZIMA, MéTODO DE PRODUçãO DE UM áCIDO GRAXO DESSATURADO, SEMENTE, óLEO, MéTODO DE PRODUçãO DE óLEO DE SEMENTE, MéTODO DE OBTENçãO DE UM FRAGMENTO DE áCIDO NUCLéICO E PRODUTO". A presente invenção refere-se a um fragmento de ácido nueléico isolado que codifica uma enzima envolvida na biossintese de lipidios. A invenção também se refere à construção de um gene quimérico que codifica toda ou uma parte da enzima envolvida na biossintese de lipidios, em orientação de sentido e anti-sentido, sendo que a expressão do gene quimérico resulta na produção de níveis alterados da enzima envolvida na biossíntese de lipídios em uma célula hospedeira transformada.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7873698P | 1998-03-20 | 1998-03-20 | |
| PCT/US1999/005471 WO1999049050A2 (en) | 1998-03-20 | 1999-03-12 | Limanthes oil genes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9908381A true BR9908381A (pt) | 2002-06-11 |
Family
ID=22145915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9908381-7A BR9908381A (pt) | 1998-03-20 | 1999-03-12 | Fragmento de ácido nucléico isolado, gene quimérico, célula hospedeira transformada, polipetìdio, processo de alteração do nìvel de expressão de uma enzima, método de produção de um ácido graxo dessaturado, semente, óleo, método de produção de óleo de semente, método de obtenção de um fragmento de ácido nucléico e produto |
Country Status (14)
| Country | Link |
|---|---|
| EP (3) | EP1064387B1 (pt) |
| JP (1) | JP2002528048A (pt) |
| KR (1) | KR20010042015A (pt) |
| AR (1) | AR015734A1 (pt) |
| AU (1) | AU763296B2 (pt) |
| BR (1) | BR9908381A (pt) |
| CA (2) | CA2783215C (pt) |
| DE (1) | DE69938961D1 (pt) |
| ES (1) | ES2310033T3 (pt) |
| HU (1) | HUP0102912A3 (pt) |
| NO (1) | NO20004680L (pt) |
| NZ (1) | NZ505988A (pt) |
| PT (1) | PT1064387E (pt) |
| WO (1) | WO1999049050A2 (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19950589A1 (de) * | 1999-10-20 | 2001-05-23 | Gvs Ges Fuer Erwerb Und Verwer | Elongasepromotoren für gewebespezifische Expression von Transgenen in Pflanzen |
| US7807849B2 (en) | 2004-04-22 | 2010-10-05 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| CA3023314C (en) | 2004-04-22 | 2019-12-10 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| WO2007012576A2 (en) * | 2005-07-25 | 2007-02-01 | Basf Plant Science | Combination of lipid metabolism proteins and uses thereof |
| US7723574B2 (en) | 2005-11-24 | 2010-05-25 | Basf Plant Science Gmbh | Process for the production of Δ5-unsaturated fatty acids in transgenic organisms |
| JP2009543561A (ja) | 2006-07-14 | 2009-12-10 | コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガニゼイション | イネの脂肪酸組成の改変 |
| WO2008025068A1 (en) | 2006-08-29 | 2008-03-06 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of fatty acids |
| AU2009273755A1 (en) | 2008-07-21 | 2010-01-28 | Commonwealth Scientific And Industrial Research Organisation | Improved vegetable oils and uses therefor |
| WO2010009499A1 (en) | 2008-07-21 | 2010-01-28 | Commonwealth Scientific And Industrial Research Organisation | Improved cottonseed oil and uses |
| CN102317459A (zh) | 2008-11-18 | 2012-01-11 | 联邦科学技术研究组织 | 产生ω-3脂肪酸的酶和方法 |
| RU2636344C2 (ru) | 2010-06-28 | 2017-11-22 | Коммонуэлт Сайентифик энд Индастриал Рисерч Организейшн | Способы получения липидов |
| JP6461604B2 (ja) | 2011-12-27 | 2019-01-30 | コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション | 脂質製造のための工程 |
| US8809026B2 (en) | 2011-12-27 | 2014-08-19 | Commonwealth Scientific And Industrial Research Organisation | Processes for producing lipids |
| US11639507B2 (en) | 2011-12-27 | 2023-05-02 | Commonwealth Scientific And Industrial Research Organisation | Processes for producing lipids |
| HK1207938A1 (en) | 2012-04-25 | 2016-02-19 | Commonwealth Scientific And Industrial Research Organisation | High oleic acid oils |
| HUE033766T2 (en) | 2012-06-15 | 2018-01-29 | Commw Scient Ind Res Org | Production of long chain polyunsaturated fatty acids in plant cells |
| CA3241340A1 (en) | 2013-12-18 | 2015-06-25 | Grains Research And Development Corporation | Lipid comprising long chain polyunsaturated fatty acids |
| EP3160482A4 (en) | 2014-06-27 | 2018-02-14 | Commonwealth Scientific and Industrial Research Organisation | Lipid comprising docosapentaenoic acid |
| MX376551B (es) | 2014-07-07 | 2025-03-07 | Nuseed Global Innovation Ltd | Procesos para producir productos industriales de lípidos vegetales. |
| MX2019002483A (es) | 2016-09-02 | 2019-09-09 | Commw Scient Ind Res Org | Plantas con rasgos modificados. |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| ES2018274T5 (es) | 1986-03-11 | 1996-12-16 | Plant Genetic Systems Nv | Celulas vegetales resistentes a los inhibidores de glutamina sintetasa, preparadas por ingenieria genetica. |
| US5107065A (en) | 1986-03-28 | 1992-04-21 | Calgene, Inc. | Anti-sense regulation of gene expression in plant cells |
| US5231020A (en) | 1989-03-30 | 1993-07-27 | Dna Plant Technology Corporation | Genetic engineering of novel plant phenotypes |
| US5679881A (en) * | 1991-11-20 | 1997-10-21 | Calgene, Inc. | Nucleic acid sequences encoding a plant cytoplasmic protein involved in fatty acyl-CoA metabolism |
| EP0572603A1 (en) * | 1991-11-20 | 1993-12-08 | Calgene, Inc. | FATTY ACYL-CoA: FATTY ALCOHOL O-ACYLTRANSFERASES |
| DK0616644T3 (da) * | 1991-12-04 | 2003-10-27 | Du Pont | Fedtsyredesaturase-gener fra planter |
| AU5407594A (en) * | 1992-11-17 | 1994-06-08 | E.I. Du Pont De Nemours And Company | Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants |
| DE4433307A1 (de) * | 1994-09-19 | 1996-03-21 | Norddeutsche Pflanzenzucht Han | Ein isoliertes Nuckleinsäurefragment und daraus abgeleitete Produkte |
| GB9502468D0 (en) * | 1995-02-09 | 1995-03-29 | Gene Shears Pty Ltd | DNA Sequence |
| SK139999A3 (en) * | 1997-04-11 | 2000-05-16 | Calgene Llc | A nucleic acids construct, isolated nucleotide sequence, recombinant plant cell, method of biosynthesis of polyunsaturated long chain fatty acids, pharmaceutical, food and cosmetic preparation and use thereof |
| EP1033405A3 (en) * | 1999-02-25 | 2001-08-01 | Ceres Incorporated | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby |
| US7325049B2 (en) | 2000-12-29 | 2008-01-29 | Intel Corporation | Alert management messaging |
| CN102186876B (zh) * | 2008-10-14 | 2014-06-11 | 孟山都技术公司 | 来自半片藻属的脂肪酸脱饱和酶的利用 |
-
1999
- 1999-03-12 NZ NZ505988A patent/NZ505988A/en not_active IP Right Cessation
- 1999-03-12 HU HU0102912A patent/HUP0102912A3/hu unknown
- 1999-03-12 AU AU31849/99A patent/AU763296B2/en not_active Ceased
- 1999-03-12 CA CA2783215A patent/CA2783215C/en not_active Expired - Fee Related
- 1999-03-12 EP EP99913868A patent/EP1064387B1/en not_active Expired - Lifetime
- 1999-03-12 CA CA2319727A patent/CA2319727C/en not_active Expired - Fee Related
- 1999-03-12 BR BR9908381-7A patent/BR9908381A/pt not_active Application Discontinuation
- 1999-03-12 KR KR1020007010348A patent/KR20010042015A/ko not_active Withdrawn
- 1999-03-12 EP EP08006579A patent/EP2006385A3/en not_active Withdrawn
- 1999-03-12 ES ES99913868T patent/ES2310033T3/es not_active Expired - Lifetime
- 1999-03-12 DE DE69938961T patent/DE69938961D1/de not_active Expired - Lifetime
- 1999-03-12 WO PCT/US1999/005471 patent/WO1999049050A2/en not_active Ceased
- 1999-03-12 JP JP2000538011A patent/JP2002528048A/ja active Pending
- 1999-03-12 PT PT99913868T patent/PT1064387E/pt unknown
- 1999-03-12 EP EP20100013147 patent/EP2316949B1/en not_active Expired - Lifetime
- 1999-03-19 AR ARP990101226A patent/AR015734A1/es not_active Application Discontinuation
-
2000
- 2000-09-19 NO NO20004680A patent/NO20004680L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU3184999A (en) | 1999-10-18 |
| CA2783215A1 (en) | 1999-09-30 |
| DE69938961D1 (de) | 2008-08-07 |
| JP2002528048A (ja) | 2002-09-03 |
| HUP0102912A2 (hu) | 2001-11-28 |
| CA2319727A1 (en) | 1999-09-30 |
| KR20010042015A (ko) | 2001-05-25 |
| EP2006385A3 (en) | 2008-12-31 |
| WO1999049050A2 (en) | 1999-09-30 |
| NO20004680D0 (no) | 2000-09-19 |
| EP2316949B1 (en) | 2015-04-22 |
| EP2006385A2 (en) | 2008-12-24 |
| CA2783215C (en) | 2015-11-17 |
| AR015734A1 (es) | 2001-05-16 |
| WO1999049050A3 (en) | 1999-12-29 |
| PT1064387E (pt) | 2008-09-15 |
| EP1064387B1 (en) | 2008-06-25 |
| EP1064387A2 (en) | 2001-01-03 |
| NO20004680L (no) | 2000-11-15 |
| EP2316949A1 (en) | 2011-05-04 |
| AU763296B2 (en) | 2003-07-17 |
| NZ505988A (en) | 2003-10-31 |
| HUP0102912A3 (en) | 2003-07-28 |
| CA2319727C (en) | 2012-09-25 |
| ES2310033T3 (es) | 2008-12-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9908381A (pt) | Fragmento de ácido nucléico isolado, gene quimérico, célula hospedeira transformada, polipetìdio, processo de alteração do nìvel de expressão de uma enzima, método de produção de um ácido graxo dessaturado, semente, óleo, método de produção de óleo de semente, método de obtenção de um fragmento de ácido nucléico e produto | |
| BR9908858A (pt) | Fragmento de ácido nucléico isolado, gene quimérico, célula hospedeira transformada, polipeptìdio, método de alteração do nìvel de expressão de uma proteìna, método de obtenção de um fragmento de ácido nucléico e produto. | |
| BR9910038A (pt) | Fragmento de ácido nucléico isolado, gene quimérico, célula hospedeira transformada polipeptìdio, método de alteração do nìvel de expressão de uma enzina, método de obtenção de um fragmento de ácido nucléico, produto e método de avaliação de pelo menos um composto quanto à sua capacidade de inibir a atividade de uma enzima | |
| BR9815632A (pt) | Fragmento de ácido nucléico isolado e método de obtenção do mesmo, gene quimérico, célula hospedeira transformada, método de alteração do nìvel de expressão de uma enzima e produto | |
| Ischenko et al. | Alternative nucleotide incision repair pathway for oxidative DNA damage | |
| Kumble et al. | Endopolyphosphatases for long chain inorganic polyphosphate in yeast and mammals | |
| Yasukawa et al. | Defect in modification at the anticodon wobble nucleotide of mitochondrial tRNALys with the MERRF encephalomyopathy pathogenic mutation | |
| BR0115179A (pt) | polinucletìdeos isolados, vetor, construção de dna recombinante, método de transformação de uma célula, célula, método de produção de uma planta, planta, semente, polipeptìdeo isolado e método para isolamento de um polipeptìdeo | |
| Madore et al. | Effect of modified nucleotides on Escherichia coli tRNAGlu structure and on its aminoacylation by glutamyl‐tRNA synthetase: Predominant and distinct roles of the mnm5 and s2 modifications of U34 | |
| Aoyagi et al. | BEN1 and ZEN1 cDNAs encoding S1‐type DNases that are associated with programmed cell death in plants 1 | |
| Clarke et al. | Cloning and expression of the β-N-acetylglucosaminidase gene from Streptococcus pneumoniae: generation of truncated enzymes with modified aglycon specificity | |
| BR9815537A (pt) | Fragmento de ácido nucleico isolado, gene quimérico, célula hospedeira, planta, semente da planta e de soja, método de alteração do nìvel de expressão de uma enzima, método para a produção de ácidos graxos epoxidados e para a produção de uma enzima, método de obtenção de um fragmento de ácido nucleico e produto | |
| WO2001004147A3 (en) | Plant inositol polyphosphate phosphatase homologs | |
| BR9808484A (pt) | Fragmento de ácido nucléico isolado, gene quimérico, homozigoto de planta de soja, sementes, planta de soja, método para produção de uma planta de soja, produto de proteìna de soja, método para produção de um produto de proteìna de soja e método de utilização de um homozigoto de planta de soja | |
| DE3382210D1 (de) | Hemmungsresistente 5-enolpyruvyl-3-phosphoshikimat-synthase, herstellung und verwendung. | |
| Jost et al. | Transient DNA demethylation in differentiating mouse myoblasts correlates with higher activity of 5-methyldeoxycytidine excision repair | |
| NO20014716D0 (no) | Ny klasse enzymer i den biosyntetiske vei for produksjon av triacylglycerol og rekombinante DNA molekyler kodende for enzymene | |
| Biederbick et al. | First apyrase splice variants have different enzymatic properties | |
| NO20030229L (no) | Et cytokrom P450 enzym assosiert med syntesen av <delta>12- epoksygrupper i fettsyrer hos planter | |
| Jiang et al. | Distinct roles of catalytic and pexin-like domains in membrane-type matrix metalloproteinase (MMP)-mediated pro-MMP-2 activation and collagenolysis | |
| BR9813919A (pt) | Fragmento de ácido nucléico isolado, gene quimérico, célula hospedeira transformada, polipeptìdeo sclb^ r^, método de alteração do nìvel de expressão de uma proteìna sclb^ r^, método para obtenção de um fragmento de ácido nucléico e produto | |
| HUP0200286A2 (hu) | Izoflavon-szintetázt kódoló nukleinsav-szekvenciák | |
| WO1999055883A3 (en) | Triacylglycerol lipases | |
| BR9908100A (pt) | Fragmento de ácido nucléico isolado, gene quimérico, célula hospedeira transformada, polipeptìdeo, método de alteração do nìvel de expressão de uma enzima biossintética de carboidrato em uma célula hospedeira, método de obtenção de um fragmento de ácido nucléico e produto | |
| BR9907965A (pt) | Fragmento de ácido nucléico isolado, gene quimérico, célula hospedeira transformada, polipetìdios, processo de alteração do nìvel de expressão de uma proteìna ciclina em uma célula hospedeira, método de obtenção de um fragmento de ácido nucleìco, produto e método de avaliação de pelo menos um composto quanto à sua capacidade de inibir a atividade de uma proteìna ciclina |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |