BR9906712A - Péletes que apresentam um núcleo revestido com um antifúngico e um polìmero - Google Patents
Péletes que apresentam um núcleo revestido com um antifúngico e um polìmeroInfo
- Publication number
- BR9906712A BR9906712A BR9906712-9A BR9906712A BR9906712A BR 9906712 A BR9906712 A BR 9906712A BR 9906712 A BR9906712 A BR 9906712A BR 9906712 A BR9906712 A BR 9906712A
- Authority
- BR
- Brazil
- Prior art keywords
- pellets
- antifungal
- polymer
- core coated
- core
- Prior art date
Links
- 239000008188 pellet Substances 0.000 title abstract 5
- 229940121375 antifungal agent Drugs 0.000 title abstract 3
- 230000000843 anti-fungal effect Effects 0.000 title abstract 2
- 229920000642 polymer Polymers 0.000 title abstract 2
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 239000011247 coating layer Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000007789 sealing Methods 0.000 abstract 1
- 229920003169 water-soluble polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Patente de Invenção: <B>"PéLETES QUE APRESENTAM UM NúCLEO REVESTIDO COM UM ANTIFúNGICO E UM POLìMERO"<D>. A presente invenção refere-se a péletes que compreendem um núcleo de açúcar de 710-1180 <109>m (16-25 mesh), uma película de revestimento de um polímero solúvel em água e um agente antifúngico, e uma camada de revestimento de vedação, nos quais a concentração residual de diclorometano é abaixo de 600 ppm; a formas de dosagem farmacêuticas que compreendem os péletes e a um método de preparação dos péletes.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98202408 | 1998-07-17 | ||
| PCT/EP1999/004928 WO2000003697A1 (en) | 1998-07-17 | 1999-07-09 | Pellets having a core coated with an antifungal and a polymer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9906712A true BR9906712A (pt) | 2000-10-10 |
Family
ID=8233945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9906712-9A BR9906712A (pt) | 1998-07-17 | 1999-07-09 | Péletes que apresentam um núcleo revestido com um antifúngico e um polìmero |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US6663901B1 (pt) |
| EP (1) | EP1104291B1 (pt) |
| JP (1) | JP2002520351A (pt) |
| KR (1) | KR100549095B1 (pt) |
| AR (1) | AR019933A1 (pt) |
| AT (1) | ATE303798T1 (pt) |
| AU (1) | AU766041B2 (pt) |
| BR (1) | BR9906712A (pt) |
| CA (1) | CA2315110C (pt) |
| DE (1) | DE69927163T2 (pt) |
| DK (1) | DK1104291T3 (pt) |
| ES (1) | ES2249904T3 (pt) |
| ID (1) | ID27549A (pt) |
| IL (1) | IL137665A0 (pt) |
| MY (1) | MY122469A (pt) |
| NZ (1) | NZ505245A (pt) |
| RU (1) | RU2219909C2 (pt) |
| SI (1) | SI1104291T1 (pt) |
| TR (1) | TR200002217T2 (pt) |
| TW (1) | TWI240639B (pt) |
| WO (1) | WO2000003697A1 (pt) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6663901B1 (en) * | 1998-07-17 | 2003-12-16 | Janssen Pharmaceutical N.V. | Pellets having a core coated with an antifungal and a polymer |
| US9700866B2 (en) | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
| IL156310A0 (en) * | 2000-12-22 | 2004-01-04 | Baxter Int | Method for preparing submicron particle suspensions |
| US6663897B2 (en) * | 2001-02-06 | 2003-12-16 | Dsm Ip Assets B.V. | Oral itraconazole formulations and methods of making the same |
| EP1842532A3 (en) * | 2001-02-06 | 2009-04-22 | Stiefel Laboratories, Inc. | Oral sparingly water-soluble antifungal formulations and methods of making the same |
| US8071133B2 (en) | 2001-08-20 | 2011-12-06 | Stiefel Laboratories, Inc. | Oral dosage forms of water insoluble drugs and methods of making the same |
| AU2003256157A1 (en) * | 2002-08-05 | 2004-02-23 | Dsm Ip Assets B.V. | Oral dosage forms of water insoluble drugs and methods of making the same |
| EP1438960B2 (en) * | 2003-01-14 | 2012-12-19 | Acino Pharma AG | Compostion of itraconazole dispersed in a hydrophilic polymer having enhanced bioavailability |
| ES2283725T5 (es) † | 2003-01-14 | 2014-11-28 | Acino Pharma Ag | Composición bioequivalente de itraconazol dispersada en un polímero hidrófilo |
| US20050244568A1 (en) * | 2004-03-04 | 2005-11-03 | Sorsus Gmbh | Artificial fruit |
| ES2278511B1 (es) * | 2005-07-28 | 2008-06-16 | Laboratorios Almirall S.A. | Comprimidos con perfil de disolucion mejorado. |
| US20070148240A1 (en) * | 2005-12-23 | 2007-06-28 | Fang-Yu Lee | Oral formulation containing itraconazole and methods for manufacturing and using the same |
| CN101091725A (zh) * | 2006-06-23 | 2007-12-26 | 天津天士力制药股份有限公司 | 一种中药颗粒及其制备方法 |
| WO2008068299A2 (en) | 2006-12-06 | 2008-06-12 | Tibotec Pharmaceuticals Ltd. | Hydrobromide salt of an anti-hiv compound |
| US20090060983A1 (en) * | 2007-08-30 | 2009-03-05 | Bunick Frank J | Method And Composition For Making An Orally Disintegrating Dosage Form |
| RU2482839C2 (ru) * | 2007-10-31 | 2013-05-27 | МакНЕЙЛС-ППС, ИНК. | Распадающаяся в полости рта лекарственная форма |
| US20120276206A1 (en) * | 2008-03-28 | 2012-11-01 | Boehringer Ingelheim International Gmbh | Method for manufacturing acid pellets |
| US20110070286A1 (en) * | 2009-09-24 | 2011-03-24 | Andreas Hugerth | Process for the manufacture of nicotine-comprising chewing gum and nicotine-comprising chewing gum manufactured according to said process |
| US8871263B2 (en) * | 2009-09-24 | 2014-10-28 | Mcneil-Ppc, Inc. | Manufacture of tablet in a die utilizing radiofrequency energy and meltable binder |
| US20110318411A1 (en) | 2010-06-24 | 2011-12-29 | Luber Joseph R | Multi-layered orally disintegrating tablet and the manufacture thereof |
| CN102100678B (zh) * | 2011-02-18 | 2012-10-17 | 天津力生制药股份有限公司 | 伊曲康唑硫酸盐微丸及其制备方法 |
| US9233491B2 (en) | 2012-05-01 | 2016-01-12 | Johnson & Johnson Consumer Inc. | Machine for production of solid dosage forms |
| US9511028B2 (en) | 2012-05-01 | 2016-12-06 | Johnson & Johnson Consumer Inc. | Orally disintegrating tablet |
| US9445971B2 (en) | 2012-05-01 | 2016-09-20 | Johnson & Johnson Consumer Inc. | Method of manufacturing solid dosage form |
| ES2750323T3 (es) | 2014-01-10 | 2020-03-25 | Johnson & Johnson Consumer Inc | Método para la fabricación de un comprimido mediante radiofrecuencia y partículas recubiertas con pérdida |
| US10493026B2 (en) | 2017-03-20 | 2019-12-03 | Johnson & Johnson Consumer Inc. | Process for making tablet using radiofrequency and lossy coated particles |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2941081B2 (ja) * | 1991-03-26 | 1999-08-25 | 株式会社奈良機械製作所 | 結晶性有機化合物の非晶質割合の増加と再結晶化を抑制する方法 |
| PH30929A (en) * | 1992-09-03 | 1997-12-23 | Janssen Pharmaceutica Nv | Beads having a core coated with an antifungal and a polymer. |
| DE4236025A1 (de) * | 1992-10-24 | 1994-04-28 | Merck Patent Gmbh | Orale Arzneiformen |
| CA2258683C (en) * | 1996-06-28 | 2007-07-31 | Schering Corporation | Oral composition comprising a triazole antifungal compound |
| IL129575A (en) * | 1997-03-26 | 2004-06-20 | Janssen Pharmaceutica Nv | Pills with a core coated with a fungicide and polymer |
| US6663901B1 (en) * | 1998-07-17 | 2003-12-16 | Janssen Pharmaceutical N.V. | Pellets having a core coated with an antifungal and a polymer |
-
1999
- 1999-07-09 US US09/582,551 patent/US6663901B1/en not_active Expired - Lifetime
- 1999-07-09 NZ NZ505245A patent/NZ505245A/en not_active IP Right Cessation
- 1999-07-09 ID IDW20001335A patent/ID27549A/id unknown
- 1999-07-09 WO PCT/EP1999/004928 patent/WO2000003697A1/en not_active Ceased
- 1999-07-09 AU AU50374/99A patent/AU766041B2/en not_active Ceased
- 1999-07-09 DK DK99934683T patent/DK1104291T3/da active
- 1999-07-09 EP EP99934683A patent/EP1104291B1/en not_active Expired - Lifetime
- 1999-07-09 BR BR9906712-9A patent/BR9906712A/pt not_active Application Discontinuation
- 1999-07-09 RU RU2000120913/15A patent/RU2219909C2/ru not_active IP Right Cessation
- 1999-07-09 TR TR2000/02217T patent/TR200002217T2/xx unknown
- 1999-07-09 AT AT99934683T patent/ATE303798T1/de active
- 1999-07-09 JP JP2000559832A patent/JP2002520351A/ja active Pending
- 1999-07-09 SI SI9930847T patent/SI1104291T1/sl unknown
- 1999-07-09 DE DE69927163T patent/DE69927163T2/de not_active Expired - Lifetime
- 1999-07-09 IL IL13766599A patent/IL137665A0/xx unknown
- 1999-07-09 ES ES99934683T patent/ES2249904T3/es not_active Expired - Lifetime
- 1999-07-09 KR KR1020007006869A patent/KR100549095B1/ko not_active Expired - Fee Related
- 1999-07-09 CA CA002315110A patent/CA2315110C/en not_active Expired - Fee Related
- 1999-07-13 TW TW088111807A patent/TWI240639B/zh not_active IP Right Cessation
- 1999-07-13 MY MYPI99002946A patent/MY122469A/en unknown
- 1999-07-16 AR ARP990103523A patent/AR019933A1/es unknown
-
2003
- 2003-10-15 US US10/685,676 patent/US20040081696A1/en not_active Abandoned
-
2004
- 2004-12-17 US US11/015,940 patent/US20050142188A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20050142188A1 (en) | 2005-06-30 |
| NZ505245A (en) | 2001-12-21 |
| KR100549095B1 (ko) | 2006-02-06 |
| ES2249904T3 (es) | 2006-04-01 |
| DE69927163D1 (de) | 2005-10-13 |
| MY122469A (en) | 2006-04-29 |
| CA2315110C (en) | 2006-09-12 |
| AU766041B2 (en) | 2003-10-09 |
| KR20010015888A (ko) | 2001-02-26 |
| EP1104291A1 (en) | 2001-06-06 |
| AR019933A1 (es) | 2002-03-27 |
| CA2315110A1 (en) | 2000-01-27 |
| ID27549A (id) | 2001-04-12 |
| IL137665A0 (en) | 2001-10-31 |
| US20040081696A1 (en) | 2004-04-29 |
| SI1104291T1 (sl) | 2006-02-28 |
| JP2002520351A (ja) | 2002-07-09 |
| ATE303798T1 (de) | 2005-09-15 |
| TR200002217T2 (tr) | 2001-02-21 |
| WO2000003697A1 (en) | 2000-01-27 |
| RU2219909C2 (ru) | 2003-12-27 |
| DE69927163T2 (de) | 2006-06-29 |
| DK1104291T3 (da) | 2006-01-16 |
| AU5037499A (en) | 2000-02-07 |
| US6663901B1 (en) | 2003-12-16 |
| TWI240639B (en) | 2005-10-01 |
| EP1104291B1 (en) | 2005-09-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: ALTERADA DE INT.CL: A61K 31/4196, A61K 9/50, A61P 31/10 Ipc: A61K 31/4196 (2007.10), A61K 9/50 (2007.10), A61P |
|
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM ART. 8O DA LPI. |