[go: up one dir, main page]

BR9902019A - Moléculas de polinucleotìdios que codificam proteìnas de neospora. - Google Patents

Moléculas de polinucleotìdios que codificam proteìnas de neospora.

Info

Publication number
BR9902019A
BR9902019A BR9902019-0A BR9902019A BR9902019A BR 9902019 A BR9902019 A BR 9902019A BR 9902019 A BR9902019 A BR 9902019A BR 9902019 A BR9902019 A BR 9902019A
Authority
BR
Brazil
Prior art keywords
polynucleotide molecules
neospora
present
proteins
encode
Prior art date
Application number
BR9902019-0A
Other languages
English (en)
Inventor
David Alan Brake
Rebeca Anne Madura
Becky Ann Durtschi
Balakrishnan Rajendra Krishnan
Susan Christine Yoder
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR9902019A publication Critical patent/BR9902019A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

patente de Invenção: <B>"MOLéCULAS DE POLINUCLEOTìDIOS QUE CODIFICAM PROTEìNAS DE NEOSPORA"<D>. A presente invenção provê moléculas polinucleotídicas isoladas compreendendo seq³ências de nucleotídeos que codificam proteínas GRA1, GRA2, SAG1, MIC1, e MAG1 de Neospora caninum, bem como vetores recombinantes, células hospedeiras transformadas e proteínas expressas de forma recombinante. A presente invenção provê ainda uma molécula polinucleotídica que compreende a seq³ência de nucleotídeos do promotor bidirecional GRA1/MAG1 de N. caninum. A presente invenção provê ainda construções genéticas baseadas nas moléculas polinucleotídicas da presente invenção que são úteis na preparação de células de estirpes modificadas de Neospora para utilização em vacinas contra a neosporose.
BR9902019-0A 1998-03-26 1999-03-26 Moléculas de polinucleotìdios que codificam proteìnas de neospora. BR9902019A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7938998P 1998-03-26 1998-03-26
US11228298P 1998-12-15 1998-12-15

Publications (1)

Publication Number Publication Date
BR9902019A true BR9902019A (pt) 2000-05-02

Family

ID=26761953

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9902019-0A BR9902019A (pt) 1998-03-26 1999-03-26 Moléculas de polinucleotìdios que codificam proteìnas de neospora.

Country Status (9)

Country Link
US (2) US6600027B1 (pt)
EP (1) EP0953641A3 (pt)
JP (5) JPH11332583A (pt)
CN (1) CN1232087A (pt)
AR (1) AR015252A1 (pt)
AU (1) AU759103B2 (pt)
BR (1) BR9902019A (pt)
CA (1) CA2264260A1 (pt)
NZ (1) NZ334839A (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0953641A3 (en) * 1998-03-26 2002-03-13 Pfizer Products Inc. Polynucleotide molecules encoding neospora proteins
ES2263317B2 (es) * 2003-12-04 2007-10-01 Universidad Complutense De Madrid Uso del gen ncsag4 para el diagnostico y prevencion de la neosporosis, y como marcador para el analisis de la patogenia.
CN1997390B (zh) * 2004-04-05 2012-10-10 辉瑞产品有限公司 微流化水包油乳状液和疫苗组合物
ES2319242B1 (es) 2005-12-23 2009-12-01 Laboratorios Hipra, S.A. Aislado avirulento de neospora canimum y sus usos.
ES2326770B1 (es) 2007-07-13 2010-07-26 Universidad Complutense De Madrid Uso de un nuevo aislado de neospora caninum para el desarrollo de pruebas de diagnostico y para la fabricacion de productos para el tratamiento y prevencion de la infenccion causada por neospora.
CN104758929B (zh) * 2008-06-27 2018-05-25 硕腾有限责任公司 新颖的佐剂组合物
CN101831495B (zh) * 2010-04-30 2013-06-19 新疆出入境检验检疫局检验检疫技术中心 一种牛新孢子虫病的检测方法及应用
WO2013151666A2 (en) * 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of biologics and proteins associated with human disease
FR2994193B1 (fr) * 2012-08-02 2016-05-20 Vitamfero Souches mutantes de neospora et leurs utilisations
CN102838984B (zh) * 2012-09-12 2014-06-04 浙江理工大学 一种胰凝乳蛋白酶保护金纳米团簇荧光材料的制备方法
CN107325166A (zh) * 2017-05-15 2017-11-07 华中农业大学 柔嫩艾美耳球虫表面抗原基因sag6所编码的重组蛋白及其应用
CN110407944B (zh) * 2018-04-29 2023-04-21 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 隐孢子虫多表位基因片段cpmcef及其融合蛋白和应用
CN110183527B (zh) * 2019-05-21 2021-03-12 中国农业大学 一种新孢子虫NcMIC26抗原及其应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3940598A1 (de) * 1989-12-08 1991-06-13 Behringwerke Ag Toxoplasma gondii-antigene, ihre herstellung und ihre verwendung
FR2625099B1 (fr) * 1987-12-24 1991-06-14 Transgene Sa Proteines et leur procede de preparation, sequences d'adn, anticorps et leur application, poxvirus, cellules transformees ou infectees et compositions pharmaceutiques utiles dans la prevention de la toxoplasmose
US5665542A (en) * 1989-11-03 1997-09-09 Research Institute Of Palo Alto Medical Foundation Toxoplasma gondii P28 gene and methods for its use
FR2692282B1 (fr) * 1992-06-15 1995-07-13 Pasteur Institut Clonage du gene codant pour la proteine gp28.5 de t. gondii; fragments peptidiques issus de ladite proteine et leurs applications.
US5976553A (en) 1993-11-04 1999-11-02 The Board Of Trustees Of The Leland Stanford Junior University Transfection and genetic manipulations in obligate intracellular parasites
US5643718A (en) 1993-11-04 1997-07-01 The Board Of Trustees Of The Leland Stanford Junior University Transfection and genetic manipulations in obligate intracellular parasites
FR2714074B1 (fr) * 1993-12-20 1996-03-01 Pasteur Institut Promoteurs des gènes GRA1, GRA2, GRA5 et GRA6 de toxoplasma gondii et vecteurs d'expression comprenant lesdits promoteurs.
US5889166A (en) * 1996-05-10 1999-03-30 The Regents Of The University Of California Recombinant neospora antigens and their uses
US5707617A (en) 1994-03-21 1998-01-13 The Regents Of The University Of California Bovine neospora isolates
AU7677896A (en) 1995-11-09 1997-05-29 Trustees Of Dartmouth College A vaccine against toxoplasma gondii
US6476192B1 (en) * 1996-04-15 2002-11-05 Nicola C. Lally Recombinant antigens useful for the serodiagnosis of neosporosis
AUPO188396A0 (en) 1996-08-26 1996-09-19 Insearch Limited Detection of protozoan parasites
EP0841392B1 (en) * 1996-11-12 2004-07-14 Pfizer Inc. Attenuated live neospora vaccine
AUPO690397A0 (en) 1997-05-20 1997-06-12 Insearch Limited Large subunit ribosomal dna of neospora species
BR9803232A (pt) * 1997-08-26 2000-01-11 Pfizer Prod Inc Vaicna de neospora.
JP2001520205A (ja) 1997-10-20 2001-10-30 バイエル・コーポレーシヨン ネオスポラワクチン
US6071737A (en) 1998-03-16 2000-06-06 The Regents Of The University Of California Equine Neospora isolate and its uses
EP0953641A3 (en) * 1998-03-26 2002-03-13 Pfizer Products Inc. Polynucleotide molecules encoding neospora proteins
AUPP371798A0 (en) 1998-05-26 1998-06-18 Insearch Limited Parasite antigens
US20040131633A1 (en) * 1999-04-21 2004-07-08 University Of Technology, Sydney Parasite antigens

Also Published As

Publication number Publication date
AU759103B2 (en) 2003-04-03
NZ334839A (en) 2000-08-25
EP0953641A3 (en) 2002-03-13
JP2005211082A (ja) 2005-08-11
US20030180785A1 (en) 2003-09-25
JP2005253467A (ja) 2005-09-22
EP0953641A2 (en) 1999-11-03
JP2005245456A (ja) 2005-09-15
US6600027B1 (en) 2003-07-29
AU2243799A (en) 1999-10-07
JP2005211081A (ja) 2005-08-11
CA2264260A1 (en) 1999-09-26
AR015252A1 (es) 2001-04-18
CN1232087A (zh) 1999-10-20
JPH11332583A (ja) 1999-12-07

Similar Documents

Publication Publication Date Title
BR9902019A (pt) Moléculas de polinucleotìdios que codificam proteìnas de neospora.
ATE352626T1 (de) Polypeptide mit galaktoseoxidaseaktivität und dafür kodierende nukleisäuren
DE69840230D1 (de) Polypeptide mit prolyldipeptidylaminopeptidase-aktivität und dafür kodierende nukleinsäuren
WO2000003685A3 (en) Nitrilase homologs
SI1618128T1 (sl) Cepivo proti tuberkolozi z izboljšano učinkovitostjo
DK0719328T3 (da) Genet GRB 3-3, varianter deraf og anvendelse deraf
TW200716166A (en) Lawsonia intracellularis immunological proteins
AR012744A1 (es) Molecula de acido nucleico que codifica una proteina vinculadora de sucrosa, proteina vinculadora de sucrosa y metodo para producir una proteinavinculadora de sucrosa.
AR061393A1 (es) Componentes transportadores de nitrato
IL174645A0 (en) MODIFIED cDNA FOR HIGH EXPRESSION LEVELS OF FACTOR VIII AND ITS DERIVATIVES
ATE317896T1 (de) Polypeptide mit glucanotransferase aktivität und dafür kodierende nukleinsäuren
MXPA01004353A (es) Antigenos de chlamydia y los correspondientes fragmentos de adn y usos de los mismos.
EP1221487A3 (en) Polynucleotide molecules encoding neospora proteins
MXPA01001639A (es) Antigenos de chlamydia y los correspondientes fragmentos de adn y usos de los mismos.
ATE298348T1 (de) Mutmassliches 98 kd protein des aussenmembrans von chlamydia und dafür kodierende dns sowie deren verwendung
ATE474927T1 (de) Schützende hochmolekulargewichtsproteine aus haemophilus influenzae
WO2002024910A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding them, and uses thereof
WO2003070882A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and used thereof
ATE408713T1 (de) Nukleotidsequenz codierend für ein tolc, das eine heterologe aminosäuresequenz enthält
TH39470A3 (th) โพลีนิวคลีโอไทด์ โมเลกุล ซึ่งเข้ารหัส นีโอสโปรา โปรตีน
AU2003225666A8 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
AU2003215212A8 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
DK0663955T3 (da) Nucleinsyre, som koder for en alfa-acetolactat-decarboxylase, og anvendelser deraf

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 1994 DE 24/03/2009