[go: up one dir, main page]

BR9816013A - Proteìna de ligação de interleucina-18 - Google Patents

Proteìna de ligação de interleucina-18

Info

Publication number
BR9816013A
BR9816013A BR9816013-3A BR9816013A BR9816013A BR 9816013 A BR9816013 A BR 9816013A BR 9816013 A BR9816013 A BR 9816013A BR 9816013 A BR9816013 A BR 9816013A
Authority
BR
Brazil
Prior art keywords
protein
substance
binding
binding protein
interleukin
Prior art date
Application number
BR9816013-3A
Other languages
English (en)
Inventor
Kakuji Torigoe
Madoka Taniai
Masashi Kurimoto
Original Assignee
Hayashibara Biochem Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hayashibara Biochem Lab filed Critical Hayashibara Biochem Lab
Publication of BR9816013A publication Critical patent/BR9816013A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"PROTEìNA DE LIGAçãO DE INTERLEUCINA-18". Os objetivos desta invenção são prover uma substância que suprime as atividades fisiológicas de IL-18 através da ligação a IL-18, usos da substância, e um DNA que codifica a substância; esta invenção alcança estes objetivos por prover uma proteína de ligação de IL-18 compreendendo uma seq³ência de aminoácidos específica, um DNA que codifica esta proteína, e um supressor de IL-18 bem como agente para doenças suscetíveis contendo como um ingrediente eficaz esta proteína de ligação de IL-18.
BR9816013-3A 1998-09-01 1998-11-18 Proteìna de ligação de interleucina-18 BR9816013A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP24758898 1998-09-01
JP32791498 1998-11-18
PCT/JP1998/005186 WO2000012555A1 (en) 1998-09-01 1998-11-18 Interleukin 18-binding protein

Publications (1)

Publication Number Publication Date
BR9816013A true BR9816013A (pt) 2003-01-21

Family

ID=26538338

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9816013-3A BR9816013A (pt) 1998-09-01 1998-11-18 Proteìna de ligação de interleucina-18

Country Status (6)

Country Link
US (1) US20050191303A1 (pt)
EP (1) EP1110969A4 (pt)
KR (1) KR100537558B1 (pt)
BR (1) BR9816013A (pt)
CA (1) CA2340579A1 (pt)
WO (1) WO2000012555A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220717B2 (en) 1997-08-14 2007-05-22 Yeda Research And Development Company Ltd. Interleukin-18 binding proteins, their preparation and use
US7704944B2 (en) 1997-08-14 2010-04-27 Yeda Research And Development Company Ltd. Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis
IL121860A0 (en) 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
CN102206277A (zh) 2000-02-10 2011-10-05 雅培制药有限公司 结合人白介素-18的抗体及制备和使用方法
KR20070087256A (ko) * 2000-02-21 2007-08-27 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. Ｉｌ-18 저해물질의 용도
EA007014B1 (ru) * 2000-05-05 2006-06-30 Апплайд Резеч Системз Арс Холдинг Н.В. Применение il-18 в качестве диагностического маркера
US6818444B2 (en) 2000-08-04 2004-11-16 Heska Corporation Canine and feline proteins, nucleic acid molecules and uses thereof
CA2424983A1 (en) 2000-10-11 2002-04-18 Viron Therapeutics, Inc. Nucleic acid molecules and polypeptides for immune modulation
US7718368B2 (en) 2000-12-04 2010-05-18 Viron Therapeutics Inc. Immunomodulatory protein and useful embodiments thereof
PT1339737E (pt) * 2000-12-04 2007-09-03 Viron Therapeutics Inc Proteína imunomoduladora derivada do vírus do tumor do macacode yaba.
EP1834960A3 (en) * 2000-12-04 2007-10-03 Viron Therapeutics, Inc. Immunomodulatory protein derived from the yaba monkey tumor virus
CZ305653B6 (cs) * 2001-01-29 2016-01-27 Merck Serono Sa Farmaceutický prostředek
EP3492100B1 (en) 2001-06-26 2021-12-08 Amgen Inc. Antibodies to opgl
UA78516C2 (en) * 2001-08-10 2007-04-10 Applied Research Systems Use of inhibitors of il-18 for treatment and/or prevention of hypersensitivity disorders, and in particular of delayed-type hypersensitivity
PL207303B1 (pl) * 2002-03-22 2010-11-30 Inst Nat Sante Rech Med Zastosowanie inhibitora IL-18 do leczenia i/lub zapobiegania chorobom naczyń obwodowych i zastosowanie wektorów ekspresyjnych
MXPA05007019A (es) 2002-12-30 2005-08-18 Amgen Inc Terapia de combinacion con factores co-estimuladores.
US20080076708A1 (en) * 2003-05-13 2008-03-27 Valter Altarocca Active Variants of the Il-18 Binding Protein and Medical Uses Thereof
DK1689777T3 (da) 2003-11-05 2007-06-11 Ares Trading Sa Fremgangsmåde til oprensning af il18-bindende protein
US20050100965A1 (en) 2003-11-12 2005-05-12 Tariq Ghayur IL-18 binding proteins
NZ549040A (en) 2004-02-17 2009-07-31 Schering Corp Use for interleukin-33 (IL33) and the IL-33 receptor complex
DE602005009827D1 (de) * 2004-06-29 2008-10-30 Ares Trading Sa Verfahren zur aufreinigung von il-18-bindendem protein
US7141382B1 (en) 2004-10-12 2006-11-28 Parikh Chirag R Methods for detection of IL-18 as an early marker for diagnosis of acute renal failure and predictor of mortality
SI1888100T1 (sl) 2005-06-03 2012-01-31 Merck Serono Sa Uporaba izooblik il-18pb za zdravljenje in/ali prepreäśevanje nevroloĺ kih vnetnih bolezni
US20100028328A1 (en) * 2006-06-12 2010-02-04 Therakine, Ltd. Topical treatment for diseases of eye surface
CL2008002153A1 (es) * 2007-07-24 2009-06-05 Amgen Inc Anticuerpo aislado o fragmanto de unión de antigeno del mismo que se une al receptor de il-18 (il-18r); molecula de ácido nucleico codificante; celula huesped que la comprende; composición farmaceutica; uso médico para tratar o prevenir una condición asociada con il-18r; método in vitro para inhibir la unión de il-18 al il-18r.
CA2972689A1 (en) * 2015-03-05 2016-09-09 Ab2 Bio Sa Il-18 binding protein (il-18bp) and antibodies in inflammatory diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087116A (en) * 1997-03-12 2000-07-11 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Interleukin-18 (IL-18) receptor polypeptides and their uses
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use

Also Published As

Publication number Publication date
KR20010074925A (ko) 2001-08-09
WO2000012555A1 (en) 2000-03-09
EP1110969A1 (en) 2001-06-27
EP1110969A4 (en) 2002-01-09
US20050191303A1 (en) 2005-09-01
CA2340579A1 (en) 2000-03-09
KR100537558B1 (ko) 2005-12-19

Similar Documents

Publication Publication Date Title
BR9816013A (pt) Proteìna de ligação de interleucina-18
BR0314356A (pt) Formulações de liberação retardada para administração oral de um agente terapêutico polipetìdeo e métodos utilizando as mesmas
BR0114927A (pt) Composição de gel farmacêutica substancialmente não aquosa para aplicação na pele, e, uso da composição
PA8426301A1 (es) Bikunina humana
DK0910647T3 (da) Human DNase i hyperaktive varianter
BR0317747A (pt) Método de tratamento terapêutico concomitante de um indivìduo, composição farmacêutica, kit, uso de um primeiro agente e um segundo agente, e, métodos de prevenir ou tratar uma doença relacionada com amilóide-b, doença de alzheimer e insuficiência cognitiva suave
AR012540A1 (es) COMPOSICIoN FARMACÉUTICA LIOFILIZADA DE ANTICUERPOS MONOCLONALES O POLICLONALES, PROCEDIMIENTO PARA SU PRODUCCIoN
ES2179910T3 (es) Modificacion cristalina del cdch, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen.
BRPI0519170A8 (pt) formulações de hormônio de crescimento humano que compreendem um aminoácido não naturalmente codificado
DK1673475T3 (da) Sammensætninger til diagnose og terapi af sygdomme, som er forbundet med aberrant ekspression af futriner (R-Spondiner) og/eller Wnt
ECSP034883A (es) Amidas de acidos antranilicos con cadena lateral de heteroarilsulfonilo, procedimiento para su preparacion, su empleo como medicamento o agente de diagnostico, asi como preparados farmaceuticos que las contienen
WO2000015826A3 (en) Leptin induced genes
BR9811094A (pt) Agente terapêutico para tumores linfáticos
BR9508467A (pt) Composição de matéria peptídeo de ligação de receptor de somatostatina composição farmacéutica e processo para realizar uma cirurgia guiada por radiosótopos ou um procedimento de radiodiagnóstico ou radioterapéutico e para aliviar uma doença relacionada com somatostetina em um animal
BR9912223A (pt) Agente terapêutico para crise hipercalcêmica
BR0010983A (pt) Preparações para a aplicação de agentes antiinflamatórios
BR9911917A (pt) Composições compreendendo análogos de gaba e cafeìna
ES2061521T3 (es) Proteinas con actividad glutation-s-transferasa, secuencias de adn, anticuerpos, poxvirus y medicamentos para la prevencion de la equistosomiasis.
MX9703364A (es) Peptidos capaces de unirse al dominio sh3 de la proteina gap, secuencias nucleotidicas que codifican para estos peptidos, su preparacion y su uso.
ES2159306T3 (es) Vacuna contra coccidiosis en pollos.
BR0109279A (pt) Antagonistas de lhrh, sua preparação e aplicação como medicamento
BRPI0418017A (pt) medicamento compreendendo inibidores de pentraxina ptx3 longa
BR9810452A (pt) Nova combinação de medicamentos contra asma
ES2147519A1 (es) Utilizacion de un compuesto de tipo retinoide para modular in vivo la actividad desacopladora de la proteina ucp2.
EA199901061A1 (ru) Новые соли врс-пептидов с органопротективной активностью, способ их получения и их использование в терапии

Legal Events

Date Code Title Description
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 37, SUGIRO O INDEFERIMENTO DO PRESENTE PEDIDO, TENDO POR BASE O ART. 10 (IX) DA LPI 9279 DE 14/05/96.