BR9508467A - Composição de matéria peptídeo de ligação de receptor de somatostatina composição farmacéutica e processo para realizar uma cirurgia guiada por radiosótopos ou um procedimento de radiodiagnóstico ou radioterapéutico e para aliviar uma doença relacionada com somatostetina em um animal - Google Patents

Composição de matéria peptídeo de ligação de receptor de somatostatina composição farmacéutica e processo para realizar uma cirurgia guiada por radiosótopos ou um procedimento de radiodiagnóstico ou radioterapéutico e para aliviar uma doença relacionada com somatostetina em um animal

Info

Publication number: BR9508467A
Authority: BR; Brazil
Prior art keywords: radiodiagnostic; somatostetin; radiosotope; alleviating; animal
Prior art date: 1994-07-29

Application number

BR9508467A

Other languages

English (en)

Inventor

Richard T Dean

William Mcbride

John Lister-James

Original Assignee

Diatide Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-07-29

Filing date

1995-07-20

Publication date

1997-12-23

1995-07-20 Application filed by Diatide Inc filed Critical Diatide Inc

1997-12-23 Publication of BR9508467A publication Critical patent/BR9508467A/pt

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
238000000034 method Methods 0.000 title abstract 3
230000003439 radiotherapeutic effect Effects 0.000 title abstract 3
108050001286 Somatostatin Receptor Proteins 0.000 title 1
102000011096 Somatostatin receptor Human genes 0.000 title 1
201000010099 disease Diseases 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
239000000203 mixture Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
238000001356 surgical procedure Methods 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 5
239000003153 chemical reaction reagent Substances 0.000 abstract 3
102000001189 Cyclic Peptides Human genes 0.000 abstract 1
108010069514 Cyclic Peptides Proteins 0.000 abstract 1
102000005157 Somatostatin Human genes 0.000 abstract 1
108010056088 Somatostatin Proteins 0.000 abstract 1
NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 abstract 1
229960000553 somatostatin Drugs 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Optics & Photonics (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

BR9508467A 1994-07-29 1995-07-20 Composição de matéria peptídeo de ligação de receptor de somatostatina composição farmacéutica e processo para realizar uma cirurgia guiada por radiosótopos ou um procedimento de radiodiagnóstico ou radioterapéutico e para aliviar uma doença relacionada com somatostetina em um animal BR9508467A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/282,980 US5932189A (en)	1994-07-29	1994-07-29	Cyclic peptide somatostatin analogs
PCT/US1995/009276 WO1996004308A1 (en)	1994-07-29	1995-07-20	Cyclic hexapeptide somatostatin analogues

Publications (1)

Publication Number	Publication Date
BR9508467A true BR9508467A (pt)	1997-12-23

Family

ID=23083971

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9508467A BR9508467A (pt)	1994-07-29	1995-07-20	Composição de matéria peptídeo de ligação de receptor de somatostatina composição farmacéutica e processo para realizar uma cirurgia guiada por radiosótopos ou um procedimento de radiodiagnóstico ou radioterapéutico e para aliviar uma doença relacionada com somatostetina em um animal

Country Status (14)

Country	Link
US (2)	US5932189A (pt)
EP (1)	EP0775160B1 (pt)
JP (1)	JP3117218B2 (pt)
KR (1)	KR100322161B1 (pt)
CN (1)	CN1181096C (pt)
AT (1)	ATE273997T1 (pt)
AU (1)	AU702917B2 (pt)
BR (1)	BR9508467A (pt)
CA (1)	CA2195395C (pt)
DE (1)	DE69533399T2 (pt)
DK (1)	DK0775160T3 (pt)
ES (1)	ES2224131T3 (pt)
WO (1)	WO1996004308A1 (pt)
ZA (1)	ZA956254B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SG90060A1 (en) *	1993-07-15	2002-07-23	Diatide Inc	Radiolabeled peptides
US6083480A (en)	1997-05-01	2000-07-04	Diatide, Inc.	Calcitonin receptor binding reagents
US6358491B1 (en) *	1999-08-27	2002-03-19	Berlex Laboratories, Inc.	Somatostatin analogs
US6579967B1 (en)	1999-12-14	2003-06-17	The Salk Institute For Biological Studies	Receptor-selective somatostatin analogs
GB0002952D0 (en) *	2000-02-09	2000-03-29	Pharma Mar Sa	Process for producing kahalalide F compounds
IL141276A0 (en) *	2001-02-05	2002-03-10	Peptor Ltd	Backbone cyclized radiolabelled somatostatin analogs
US7019109B2 (en) *	2001-03-16	2006-03-28	The Salk Institute For Bilogical Studies	SSTR1-selective analogs
KR100738362B1 (ko) *	2001-03-19	2007-07-12	재단법인서울대학교산학협력재단	신규한 디아민디티올 유도체 및 그의 방사성 레늄 또는방사성 테크네슘 착체； 그리고, 그의 방사성 레늄 착체와리피오돌을 포함하는 간암 치료용 조성물 및 그의 제조용키트
US20050054555A1 (en) *	2001-10-19	2005-03-10	Jose Jimeno	Kahalalide compounds for use in cancer therapy
DE10215336A1 (de) *	2002-03-28	2003-10-23	Schering Ag	N-Methyl-Homocysteine und ihre Verwendung sowie Verfahren zu ihrer Herstellung
IL150384A0 (en) *	2002-06-24	2002-12-01	Peptor Ltd	Radiolabelled somatostatin analogs backbone cyclized through metal complexation
AU2003259172A1 (en) *	2002-07-24	2004-02-09	The Salk Institute For Biological Studies	Receptor (sstr4)- selective somatostatin analogs
GB0304367D0 (en) *	2003-02-26	2003-04-02	Pharma Mar Sau	Methods for treating psoriasis
US7507708B2 (en)	2003-02-26	2009-03-24	Pharma Mar, S.A.U.	Antitumoral compounds
GB0408958D0 (en) *	2004-04-22	2004-05-26	Pharma Mar Sa	Convergent synthesis for kahalalide compounds
EP1717247A1 (en) *	2005-04-28	2006-11-02	Schering AG	Cyclic peptides binding to the somatostatin receptor
WO2006114324A1 (en) *	2005-04-28	2006-11-02	Schering Ag	Compounds comprising cyclized somatostatin receptor binding peptides
US20070025910A1 (en)	2005-07-29	2007-02-01	Norenberg Jeffrey P	Anticancer therapy
US20070231258A1 (en) *	2006-03-31	2007-10-04	Karyon Ctt Ltd.	Peptide conjugates
ES2351569B8 (es) *	2009-05-07	2012-06-20	Bcn Peptides S.A.	Ligandos peptídicos de receptores de somatostatina.
US9005575B2 (en)	2009-06-12	2015-04-14	Stc.Unm	Arg-Gly-Asp-conjugated alpha-melanocyte stimulating hormone hybrid peptide for use in diagnosing and treating melanoma, including metastatic melanoma and methods related to same
CN118994321B (zh) *	2024-10-23	2025-02-14	杭州皓阳生物技术有限公司	一种美容环肽试剂的制备方法及其应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4235886A (en) *	1979-10-31	1980-11-25	Merck & Co., Inc.	Cyclic hexapeptide somatostatin analogs
US4310518A (en) *	1979-10-31	1982-01-12	Merck & Co., Inc.	Cyclic hexapeptide somatostatin analogs
NZ195303A (en) *	1979-10-31	1984-10-19	Merck & Co Inc	Cyclic hexapeptide somatostatin analogues,and pharmaceutical compositions
US4366148A (en) *	1981-06-02	1982-12-28	Brigham And Women's Hospital	Use of somatostatin in the prevention and cure of vascular, membrane, or organ lesions
DE3379657D1 (en) *	1982-12-06	1989-05-24	Merck & Co Inc	Dicyclic hexapeptides, processes for their preparation and pharmaceutical compositions containing them
US4485101A (en) *	1983-10-11	1984-11-27	Administrators Of The Tulane Educational Fund	Peptides
DE8427783U1 (de) *	1984-09-21	1985-05-15	Rheinmetall GmbH, 4000 Düsseldorf	Gefechtskopf
US4611054A (en) *	1985-04-29	1986-09-09	Merck & Co., Inc.	Cyclic hexapeptide somatostatin analogs
US4612366A (en) *	1985-06-17	1986-09-16	Merck & Co., Inc.	Cyclic hexapeptide somatostatin analogs
US4904642A (en) *	1985-09-12	1990-02-27	The Administrators Of The Tulane Educational Fund	Therapeutic somatostatin analogs
US4853371A (en) *	1986-06-17	1989-08-01	The Administrators Of The Tulane Educational Fund	Therapeutic somatostatin analogs
US4871717A (en) *	1987-01-07	1989-10-03	Administrators Of The Tulane Educational Fund	Peptides
US5073541A (en) *	1987-11-18	1991-12-17	Administrators Of The Tulane Educational Fund	Treatment of small cell lung cancer with somatostatin analogs
MY106120A (en) *	1988-12-05	1995-03-31	Novartis Ag	Peptide derivatives.
CA2012115C (en) *	1989-03-15	2001-07-03	Biomeasure, Inc.	Iodinated somatostatins
ATE140237T1 (de) *	1989-12-08	1996-07-15	Univ Tulane	Oktapeptidanaloge von somatostatin mit threonin in position 6
ES2075244T3 (es) *	1990-04-06	1995-10-01	Univ Tulane	Analogos de la somatostatina.
US5382654A (en) *	1992-02-05	1995-01-17	Mallinckrodt Medical, Inc.	Radiolabelled peptide compounds
WO1992013554A1 (en) *	1991-02-08	1992-08-20	Biomeasure, Inc.	Method of treating benign and malignant proliferative skin disease
US5620675A (en) *	1992-06-23	1997-04-15	Diatech, Inc.	Radioactive peptides
US5716596A (en) *	1992-06-23	1998-02-10	Diatide, Inc.	Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses
US5462926A (en) *	1992-07-27	1995-10-31	Biomeasure, Inc.	Neuromedin B receptor antagonists which demonstrate selectivity
SG90060A1 (en) *	1993-07-15	2002-07-23	Diatide Inc	Radiolabeled peptides
US5556939A (en) *	1994-10-13	1996-09-17	Merck Frosst Canada, Inc.	TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications
US5632969A (en) *	1994-10-13	1997-05-27	Merck & Co., Inc.	N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications

1994
- 1994-07-29 US US08/282,980 patent/US5932189A/en not_active Expired - Fee Related
1995
- 1995-07-20 KR KR1019970700606A patent/KR100322161B1/ko not_active Expired - Fee Related
- 1995-07-20 DK DK95928109T patent/DK0775160T3/da active
- 1995-07-20 US US08/776,160 patent/US5955426A/en not_active Expired - Fee Related
- 1995-07-20 EP EP95928109A patent/EP0775160B1/en not_active Expired - Lifetime
- 1995-07-20 CN CNB951949209A patent/CN1181096C/zh not_active Expired - Fee Related
- 1995-07-20 ES ES95928109T patent/ES2224131T3/es not_active Expired - Lifetime
- 1995-07-20 CA CA002195395A patent/CA2195395C/en not_active Expired - Fee Related
- 1995-07-20 BR BR9508467A patent/BR9508467A/pt not_active Application Discontinuation
- 1995-07-20 AT AT95928109T patent/ATE273997T1/de not_active IP Right Cessation
- 1995-07-20 WO PCT/US1995/009276 patent/WO1996004308A1/en not_active Ceased
- 1995-07-20 JP JP08506575A patent/JP3117218B2/ja not_active Expired - Fee Related
- 1995-07-20 AU AU31984/95A patent/AU702917B2/en not_active Ceased
- 1995-07-20 DE DE69533399T patent/DE69533399T2/de not_active Expired - Fee Related
- 1995-07-27 ZA ZA956254A patent/ZA956254B/xx unknown

Also Published As

Publication number	Publication date
JP3117218B2 (ja)	2000-12-11
DE69533399D1 (en)	2004-09-23
AU702917B2 (en)	1999-03-11
JPH10506880A (ja)	1998-07-07
KR100322161B1 (ko)	2002-03-08
EP0775160B1 (en)	2004-08-18
US5955426A (en)	1999-09-21
CA2195395A1 (en)	1996-02-15
WO1996004308A1 (en)	1996-02-15
AU3198495A (en)	1996-03-04
EP0775160A1 (en)	1997-05-28
DE69533399T2 (de)	2005-09-01
DK0775160T3 (da)	2004-10-25
ATE273997T1 (de)	2004-09-15
US5932189A (en)	1999-08-03
CN1161698A (zh)	1997-10-08
CA2195395C (en)	2001-05-01
ZA956254B (en)	1996-03-13
CN1181096C (zh)	2004-12-22
ES2224131T3 (es)	2005-03-01

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Legal Events

Date	Code	Title	Description
2002-06-25	EG	Technical examination (opinion): publication of technical examination (opinion)
2007-04-17	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: DE ACORDO COM O ART. 37 DA LPI, CONSIDERA-SE QUE O EXAME DO PEDIDO ESTA COMCLUIDO, NAO APRESENTANDO NOVIDADE INCIDINDO NOS ART.8O E 13 DA LPI. EM FACE DA COMCLUSAO A QUE CHEGOU O EXAME TECNICO INDEFIRO O PEDIDO DE PATENTE.
2007-06-19	B25A	Requested transfer of rights approved	Owner name: CIS BIO INTERNATIONAL (FR) Free format text: TRANSFERIDO POR INCORPORACAO DE: DIATIDE, INC.
2007-06-26	B25A	Requested transfer of rights approved	Owner name: CIS BIO INTERNATIONAL (FR) Free format text: TRANSFERIDO DE: BERLEX LABORATORIES, INC.
2010-07-13	B12B	Appeal against refusal [chapter 12.2 patent gazette]