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BR9814300A - Método de preparação de óxidos de tetraidrobenzotiepina enanciomericamente enriquecidos - Google Patents

Método de preparação de óxidos de tetraidrobenzotiepina enanciomericamente enriquecidos

Info

Publication number
BR9814300A
BR9814300A BR9814300-0A BR9814300A BR9814300A BR 9814300 A BR9814300 A BR 9814300A BR 9814300 A BR9814300 A BR 9814300A BR 9814300 A BR9814300 A BR 9814300A
Authority
BR
Brazil
Prior art keywords
preparation
enanciomerically
oxides
enanciomerically enriched
enriched tetrahydrobenzothiepine
Prior art date
Application number
BR9814300-0A
Other languages
English (en)
Inventor
James Li
Ching-Cheng Wang
David B Reitz
Victor Snieckus
Horng-Chih Huang
Andrew J Carpenter
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of BR9814300A publication Critical patent/BR9814300A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

Patente de Invenção: "MéTODO DE PREPARAçãO DE óXIDOS DE TETRAIDROBENZOTIEPINA ENANCIOMERICAMENTE ENRIQUECIDOS". Um processo para a preparação de óxidos de tetraidrobenzotiepina enanciomericamente enriquecidos compreende a ciclização de um sulfóxido de aril-3-propanal enanciomericamente enriquecido, em que o átomo de enxofre do sulfóxido de aril-3-propanal é um centro quiral.
BR9814300-0A 1997-12-19 1998-12-16 Método de preparação de óxidos de tetraidrobenzotiepina enanciomericamente enriquecidos BR9814300A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6817097P 1997-12-19 1997-12-19
PCT/US1998/026216 WO1999032478A1 (en) 1997-12-19 1998-12-16 Method of preparing enantiomerically-enriched tetrahydrobenzothiepine oxides

Publications (1)

Publication Number Publication Date
BR9814300A true BR9814300A (pt) 2002-02-05

Family

ID=22080853

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9814300-0A BR9814300A (pt) 1997-12-19 1998-12-16 Método de preparação de óxidos de tetraidrobenzotiepina enanciomericamente enriquecidos

Country Status (18)

Country Link
US (2) US6369220B1 (pt)
EP (1) EP1042314B1 (pt)
JP (1) JP2001526284A (pt)
KR (1) KR20010015884A (pt)
CN (2) CN1106395C (pt)
AT (1) ATE234829T1 (pt)
AU (1) AU1721399A (pt)
BR (1) BR9814300A (pt)
DE (1) DE69812419T2 (pt)
DK (1) DK1042314T3 (pt)
ES (1) ES2195428T3 (pt)
HU (1) HUP0101193A3 (pt)
IL (1) IL136864A (pt)
PT (1) PT1042314E (pt)
RU (1) RU2236406C2 (pt)
UA (1) UA67764C2 (pt)
WO (1) WO1999032478A1 (pt)
ZA (1) ZA9811648B (pt)

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JP7695242B2 (ja) 2019-12-04 2025-06-18 アルビレオ・アクチボラグ ベンゾチア（ジ）アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用
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CN114786772B (zh) 2019-12-04 2024-04-09 阿尔比里奥公司 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途
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Also Published As

Publication number Publication date
HUP0101193A3 (en) 2001-12-28
US6369220B1 (en) 2002-04-09
DE69812419T2 (de) 2003-08-14
RU2236406C2 (ru) 2004-09-20
ZA9811648B (en) 1999-12-20
ATE234829T1 (de) 2003-04-15
CN1106395C (zh) 2003-04-23
PT1042314E (pt) 2003-07-31
EP1042314A1 (en) 2000-10-11
US20020188119A1 (en) 2002-12-12
DK1042314T3 (da) 2003-07-14
KR20010015884A (ko) 2001-02-26
HK1034971A1 (en) 2001-11-09
IL136864A0 (en) 2001-06-14
WO1999032478A1 (en) 1999-07-01
EP1042314B1 (en) 2003-03-19
ES2195428T3 (es) 2003-12-01
IL136864A (en) 2004-07-25
DE69812419D1 (de) 2003-04-24
JP2001526284A (ja) 2001-12-18
HUP0101193A2 (hu) 2001-08-28
CN1284953A (zh) 2001-02-21
AU1721399A (en) 1999-07-12
CN1439638A (zh) 2003-09-03
US6875877B2 (en) 2005-04-05
UA67764C2 (uk) 2004-07-15

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1912 DE 28/08/2007.