BR9814048A - "misturas de enantiÈmetros de aminociclohexil amidas para produzir de modo simultâneo analgesia com anestesia local ou antiarritmia " - Google Patents
"misturas de enantiÈmetros de aminociclohexil amidas para produzir de modo simultâneo analgesia com anestesia local ou antiarritmia "Info
- Publication number
- BR9814048A BR9814048A BR9814048-5A BR9814048A BR9814048A BR 9814048 A BR9814048 A BR 9814048A BR 9814048 A BR9814048 A BR 9814048A BR 9814048 A BR9814048 A BR 9814048A
- Authority
- BR
- Brazil
- Prior art keywords
- local anesthesia
- enantiometers
- antiarrhythmia
- aminocyclohexyl
- mixtures
- Prior art date
Links
- 230000036592 analgesia Effects 0.000 title abstract 3
- 238000002690 local anesthesia Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000003288 anthiarrhythmic effect Effects 0.000 title abstract 2
- LHQRDAIAWDPZGH-UHFFFAOYSA-N cyclohexylhydrazine Chemical class NNC1CCCCC1 LHQRDAIAWDPZGH-UHFFFAOYSA-N 0.000 title abstract 2
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000707 stereoselective effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"MISTURAS DE ENANTIÈMETROS DE AMINOCICLOHEXIL AMIDAS PARA PRODUZIR DE MODO SIMULTâNEO ANALGESIA COM ANESTESIA LOCAL OU ANTIARRITMIA'' A presente invenção proporciona composições e métodos para oferecer analgesia durante o tratamento das arritmias cardíacas ou a indução de anestesia local. As composições da presente invenção incluem uma pluralidade de enantiómetros aminociclohexil amida vicinais em relações de configurações estéreo-específicas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6015497P | 1997-09-26 | 1997-09-26 | |
| PCT/CA1998/000905 WO1999016431A1 (en) | 1997-09-26 | 1998-09-25 | Mixtures of enantiomers of aminocyclohexylamides to produce simultaneous analgesia with local anaesthesia or antiarrhythmia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9814048A true BR9814048A (pt) | 2000-10-03 |
Family
ID=22027715
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9814048-5A BR9814048A (pt) | 1997-09-26 | 1998-09-25 | "misturas de enantiÈmetros de aminociclohexil amidas para produzir de modo simultâneo analgesia com anestesia local ou antiarritmia " |
Country Status (5)
| Country | Link |
|---|---|
| CN (1) | CN1278166A (pt) |
| AU (1) | AU9248698A (pt) |
| BR (1) | BR9814048A (pt) |
| MX (1) | MXPA00002969A (pt) |
| WO (1) | WO1999016431A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1422217A3 (en) | 1998-04-01 | 2004-06-16 | Cardiome Pharma Corp. | Aminocyclohexyl ether compounds and uses thereof |
| US7507545B2 (en) | 1999-03-31 | 2009-03-24 | Cardiome Pharma Corp. | Ion channel modulating activity method |
| US7057053B2 (en) | 2000-10-06 | 2006-06-06 | Cardiome Pharma Corp. | Ion channel modulating compounds and uses thereof |
| US7524879B2 (en) | 2000-10-06 | 2009-04-28 | Cardiome Pharma Corp. | Ion channel modulating compounds and uses thereof |
| PL227937B1 (pl) | 2003-05-02 | 2018-01-31 | Cardiome Pharma Corp | Sposób wytwarzania związku typu eteru aminocykloheksylowego, związek typu eteru aminocykloheksylowego, jego kompozycja, sposób modulowania aktywności kanałów jonowych, oraz zastosowanie związku typu eteru aminocykloheksylowego do wytwarzania leku |
| US7345086B2 (en) | 2003-05-02 | 2008-03-18 | Cardiome Pharma Corp. | Uses of ion channel modulating compounds |
| US7674820B2 (en) | 2003-08-07 | 2010-03-09 | Cardiome Pharma Corp. | Ion channel modulating activity I |
| US7345087B2 (en) | 2003-10-31 | 2008-03-18 | Cardiome Pharma Corp. | Aminocyclohexyl ether compounds and uses thereof |
| WO2005097087A2 (en) | 2004-04-01 | 2005-10-20 | Cardiome Pharma Corp. | Merged ion channel modulating compounds and uses thereof |
| MXPA06011419A (es) | 2004-04-01 | 2007-04-20 | Cardiome Pharma Corp | Profarmacos de compuestos moduladores de canales ionicos y usos de los mismos. |
| EP1868598B1 (en) | 2004-11-08 | 2014-04-23 | Cardiome Pharma Corp. | A new dosing regimen for ion channel modulating compounds for treating acute atrial fibrillation in a human |
| US10160727B2 (en) | 2014-08-06 | 2018-12-25 | Shionogi & Co., Ltd. | Heterocycle and carbocycle derivatives having TrkA inhibitory activity |
| EP3330256B1 (en) | 2015-07-07 | 2021-06-16 | Shionogi & Co., Ltd. | HETEROCYCLIC DERIVATIVE HAVING TrkA-INHIBITING ACTIVITY |
| EP3412663B1 (en) | 2016-02-04 | 2022-09-07 | Shionogi & Co., Ltd. | Nitrogen-containing heterocycle and carbocycle derivatives having trka inhibitory activity |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4212878A (en) * | 1978-01-26 | 1980-07-15 | The Upjohn Company | Phenylacetamide derivative analgesics |
| AT376669B (de) * | 1982-11-26 | 1984-12-27 | Laevosan Gmbh & Co Kg | Verfahren zur herstellung neuer thienylessigsaeureamid-derivate und pharmazeutisch vertraeglicher saeureadditionssalze davon |
| US5506257A (en) * | 1992-03-26 | 1996-04-09 | University Of British Columbia | Aminocyclohexylamides for antiarrhythmic and anaesthetic uses |
-
1998
- 1998-09-25 AU AU92486/98A patent/AU9248698A/en not_active Abandoned
- 1998-09-25 WO PCT/CA1998/000905 patent/WO1999016431A1/en not_active Ceased
- 1998-09-25 BR BR9814048-5A patent/BR9814048A/pt not_active Application Discontinuation
- 1998-09-25 CN CN98810770A patent/CN1278166A/zh active Pending
- 1998-09-25 MX MXPA00002969A patent/MXPA00002969A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999016431A1 (en) | 1999-04-08 |
| CN1278166A (zh) | 2000-12-27 |
| AU9248698A (en) | 1999-04-23 |
| MXPA00002969A (es) | 2002-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |