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BR9812590A - Composições farmacêuticas de sabor mascarado - Google Patents

Composições farmacêuticas de sabor mascarado

Info

Publication number
BR9812590A
BR9812590A BR9812590-7A BR9812590A BR9812590A BR 9812590 A BR9812590 A BR 9812590A BR 9812590 A BR9812590 A BR 9812590A BR 9812590 A BR9812590 A BR 9812590A
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
masked flavor
masked
flavor
spheres
Prior art date
Application number
BR9812590-7A
Other languages
English (en)
Other versions
BR9812590B1 (pt
Inventor
Michael Augello
Ronald S Vladyka
Sheila M Dell
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Publication of BR9812590A publication Critical patent/BR9812590A/pt
Publication of BR9812590B1 publication Critical patent/BR9812590B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: <B>"COMPOSIçõES FARMACêUTICAS DE SABOR MASCARADO"<D>. A presente invenção refere-se ao mascaramento de sabor de drogas através de granulação úmida da droga com composições de celulose microcristalina então formando esferas da granulação em esferas tendo uma superfície uniforme lisa e um tamanho de partícula na faixa de 1 a 1000 mícrons.
BRPI9812590-7A 1997-10-03 1998-09-30 processo para preparaÇço de composiÇÕes farmacÊuticas de sabor mascarado. BR9812590B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/942,962 US5904937A (en) 1997-10-03 1997-10-03 Taste masked pharmaceutical compositions
PCT/US1998/020496 WO1999017748A1 (en) 1997-10-03 1998-09-30 Taste masked pharmaceutical compositions

Publications (2)

Publication Number Publication Date
BR9812590A true BR9812590A (pt) 2000-08-01
BR9812590B1 BR9812590B1 (pt) 2009-01-13

Family

ID=25478887

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9812590-7A BR9812590B1 (pt) 1997-10-03 1998-09-30 processo para preparaÇço de composiÇÕes farmacÊuticas de sabor mascarado.

Country Status (15)

Country Link
US (1) US5904937A (pt)
EP (1) EP1027038B1 (pt)
JP (2) JP2001518491A (pt)
KR (1) KR100563342B1 (pt)
CN (1) CN1154481C (pt)
AT (1) ATE332126T1 (pt)
AU (1) AU1063799A (pt)
BR (1) BR9812590B1 (pt)
CA (1) CA2303177C (pt)
DE (1) DE69835162T2 (pt)
DK (1) DK1027038T3 (pt)
IL (1) IL135121A (pt)
NO (1) NO20001670L (pt)
PL (1) PL339568A1 (pt)
WO (1) WO1999017748A1 (pt)

Families Citing this family (46)

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EP1202716A1 (en) 1999-08-17 2002-05-08 Novartis Consumer Health S.A. Rapidly dissolving dosage form and process for making same
DE10003757A1 (de) * 2000-01-28 2001-08-02 Knoll Ag Ibuprofen-Wirkstoffzubereitung
IL134701A0 (en) 2000-02-23 2001-04-30 J P M E D Ltd Homogeneous solid matrix containing vegetable proteins
HUP0302631A2 (hu) 2000-03-30 2003-11-28 Bristol-Myers Squibb Co. Stavudint tartalmazó elnyújtott hatóanyag-kibocsátású szemcsék
EP1252886A1 (en) * 2001-04-27 2002-10-30 Universiteit Gent Controlled release pharmaceutical pellet compositions
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
US6932861B2 (en) * 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
JP2004522752A (ja) * 2001-02-05 2004-07-29 アール．ピー． シェーラー テクノロジーズ インコーポレイテッド 薬学的活性剤の味を軽減するための方法および組成物
CA2452871C (en) 2001-07-06 2011-10-04 Endo Pharmaceuticals, Inc. Oxymorphone controlled release formulations
PT1411899E (pt) * 2001-08-01 2009-04-24 Novartis Ag Composição de mascaramento de sabor
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
ES2199061B1 (es) * 2002-06-10 2005-02-16 Laboratorios Vita, S.A. Comprimidos bucodispersables y procedimiento para su obtencion.
US20040151759A1 (en) * 2002-08-16 2004-08-05 Douglas Cleverly Non-animal product containing veterinary formulations
US20040037869A1 (en) * 2002-08-16 2004-02-26 Douglas Cleverly Non-animal product containing veterinary formulations
JP2004107258A (ja) * 2002-09-18 2004-04-08 Ss Pharmaceut Co Ltd 催眠用圧縮成型製剤
EP1589944B1 (de) * 2003-02-06 2011-11-23 Gebro Pharma GmbH Pharmazeutische zubereitungen und verfahren zu deren herstellung
JP4643899B2 (ja) * 2003-10-20 2011-03-02 エスエス製薬株式会社 イブプロフェン含有錠剤およびその製造方法
CN101277721B (zh) * 2005-08-10 2011-10-05 盐野义制药株式会社 口腔崩解片
US20070036859A1 (en) * 2005-08-11 2007-02-15 Perry Ronald L Sustained release antihistamine and decongestant composition
JP2007131561A (ja) * 2005-11-09 2007-05-31 Ss Pharmaceut Co Ltd 経口固形製剤及びその製造法
US20070286903A1 (en) * 2006-06-13 2007-12-13 Becicka Brian T Composition and method for taste masking
CA2652981C (en) * 2006-10-10 2012-05-01 Penwest Pharmaceuticals Co. Robust sustained release formulations
EP1935405A1 (en) * 2006-12-22 2008-06-25 LEK Pharmaceuticals D.D. Orally disintegrating tablets
CN102202654B (zh) * 2008-09-04 2014-07-30 法纳姆公司 可咀嚼的缓释制剂
US9925282B2 (en) 2009-01-29 2018-03-27 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
WO2010115736A2 (en) 2009-04-02 2010-10-14 Merck Serono S.A. Dihydroorotate dehydrogenase inhibitors
WO2011087705A2 (en) * 2009-12-22 2011-07-21 Fmc Corporation Fine particle croscarmellose and uses thereof
AU2011315555B2 (en) * 2010-10-12 2016-03-10 Elanco Animal Health Gmbh Non-starch based soft chewables
MX350838B (es) 2011-02-11 2017-09-18 Grain Proc Corporation * Composicion de sal.
CA2889446C (en) 2012-10-25 2021-05-11 The General Hospital Corporation Combination therapies for the treatment of alzheimer's disease and related disorders
EP3019482B1 (en) 2013-02-25 2018-08-15 Aurigene Discovery Technologies Limited Trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors
BR112015023435B1 (pt) * 2013-03-15 2022-05-03 Douglas Robert Cleverly Formulação mastigável estável sob armazenagem e método de fabricação de uma formulação mastigável, palatável e estável sob armazenagem
US10525005B2 (en) 2013-05-23 2020-01-07 The General Hospital Corporation Cromolyn compositions and methods thereof
AU2014340182B2 (en) 2013-10-22 2019-05-23 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
US10335390B2 (en) 2014-09-05 2019-07-02 Symbiomix Therapeutics, Llc Secnidazole for use in the treatment of bacterial vaginosis
WO2016196653A1 (en) * 2015-06-01 2016-12-08 Symbiomix Therapeutics, Llc Novel nitroimidazole formulations and uses thereof
JP2019524865A (ja) 2016-08-31 2019-09-05 ザ ジェネラル ホスピタル コーポレイション 神経変性疾患と関連する神経炎症におけるマクロファージ／ミクログリア
EP3585772B1 (en) 2017-02-24 2023-10-11 Merck Patent GmbH 1, 4, 6-trisubstituted-2-alkyl-1h-benzo[d]imidazole derivatives as dihydroorotate oxygenase inhibitors
HRP20211462T1 (hr) 2017-04-24 2021-12-24 Aurigene Discovery Technologies Limited Postupci uporabe za trisupstituirane derivate benzotriazola kao inhibitora dihidroorotatne oksigenaze
KR20210070232A (ko) * 2017-07-20 2021-06-14 아즈테라피즈 인코포레이티드 크로몰린 나트륨 및 이부프로펜의 분말화된 제형
EP3508199A1 (en) * 2018-01-05 2019-07-10 Dompé farmaceutici S.p.A. Immediate-release pharmaceutical compositions containing ketoprofen lysine salt
CN113038944A (zh) 2018-07-02 2021-06-25 通用医疗公司 色甘酸钠和α-乳糖的粉末化制剂
AU2019397436A1 (en) 2018-12-10 2021-07-22 The General Hospital Corporation Cromolyn esters and uses thereof
EP3804531A1 (en) * 2019-10-11 2021-04-14 Begapinol Dr. Schmidt GmbH Granulation of topinambur
IL297023A (en) 2020-04-06 2022-12-01 Massachusetts Gen Hospital Methods for treating inflammatory conditions caused by the corona virus
US12280037B2 (en) 2020-09-22 2025-04-22 Evofem Biosciences, Inc. Method and pharmaceutical composition for treating or preventing trichomoniasis and uses thereof

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US4835187A (en) * 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US5084278A (en) * 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
NZ234587A (en) * 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
CA2039742A1 (en) * 1990-04-23 1991-10-24 Andrew B. Dennis Tablet composition and method for problem pharmaceutical materials
US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
US5260072A (en) * 1990-08-30 1993-11-09 Mcneil-Ppc, Inc. Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
CA2068402C (en) * 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5225201A (en) * 1991-08-23 1993-07-06 Minnesota Mining And Manufacturing Company Salsalate tablet
ES2150438T3 (es) * 1991-12-30 2000-12-01 Fmc Corp Composicion de esferonizacion a base de celulosa microcristalina.
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
EP0713389A4 (en) * 1993-08-13 1997-05-21 Bayer Ag HYDROLYZED GELATIN USED AS A TASTE ENHANCER IN CHEWABLE TABLETS
ZA945944B (en) * 1993-08-13 1996-02-08 Eurand America Inc Procedure for encapsulating nsaids
ES2082723B1 (es) * 1994-07-20 1996-10-01 Lilly Sa Formulacion farmaceutica de fluoxetina en forma dispersable.
US5637313A (en) * 1994-12-16 1997-06-10 Watson Laboratories, Inc. Chewable dosage forms
US5529783A (en) * 1994-12-19 1996-06-25 Mcneil-Ppc, Inc. Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan
US5686107A (en) * 1995-01-30 1997-11-11 Fmc Corporation Chewable pharmaceutical tablets
US5639475A (en) * 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules

Also Published As

Publication number Publication date
BR9812590B1 (pt) 2009-01-13
IL135121A0 (en) 2001-05-20
EP1027038B1 (en) 2006-07-05
JP2001518491A (ja) 2001-10-16
KR20010024375A (ko) 2001-03-26
IL135121A (en) 2005-07-25
CA2303177C (en) 2005-12-06
CN1154481C (zh) 2004-06-23
WO1999017748A1 (en) 1999-04-15
EP1027038A1 (en) 2000-08-16
CA2303177A1 (en) 1999-04-15
NO20001670L (no) 2000-05-22
NO20001670D0 (no) 2000-03-31
DK1027038T3 (da) 2006-09-18
KR100563342B1 (ko) 2006-03-22
CN1273527A (zh) 2000-11-15
ATE332126T1 (de) 2006-07-15
DE69835162T2 (de) 2007-05-31
DE69835162D1 (de) 2006-08-17
US5904937A (en) 1999-05-18
AU1063799A (en) 1999-04-27
PL339568A1 (en) 2000-12-18
JP2007137902A (ja) 2007-06-07
EP1027038A4 (en) 2005-02-09

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Free format text: R.P. SCHERER TECHNOLOGIES, INC. (US)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 25/02/2009, OBSERVADAS AS CONDICOES LEGAIS.

B24C Patent annual fee: request for for restoration

Free format text: REFERENTE A 13A E 14A ANUIDADE(S), CONFORME ART.87 DA LPI 9.279.

B24H Lapse because of non-payment of annual fees (definitively: art 78 iv lpi)
B24F Patent annual fee: publication cancelled

Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2259 DE 22/04/2014 POR TER SIDO INDEVIDA.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE AS 13A E 14A ANUIDADES.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2607 DE 22-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.