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BR9811868A - Derivados de ácido ariloxiarilsulfonilamino hidroxâmico - Google Patents

Derivados de ácido ariloxiarilsulfonilamino hidroxâmico

Info

Publication number
BR9811868A
BR9811868A BR9811868-4A BR9811868A BR9811868A BR 9811868 A BR9811868 A BR 9811868A BR 9811868 A BR9811868 A BR 9811868A BR 9811868 A BR9811868 A BR 9811868A
Authority
BR
Brazil
Prior art keywords
alkyl
substituent
derivatives
aryloxyarylsulfonylamino
hydroxyl
Prior art date
Application number
BR9811868-4A
Other languages
English (en)
Inventor
Ralph Pelton Robinson
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR9811868A publication Critical patent/BR9811868A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Surgery (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrane Compounds (AREA)

Abstract

Patente de Invenção: <B>"DERIVADOS DE áCIDO ARILOXIARILSULFONILAMINO HIDROXâMICO"<D>. Um composto de fórmula (I) em que R^ 1^ é (C~ 1~-C~ 6~)alquila; R^ 2^ é (C~ 1~-C~ 6~)alquila; ou R^ 1^ e R^ 2^ são considerados juntos com o átomo de carbono ao qual estes estão ligados a formar um anel selecionado de (C~ 5~-C~ 7~)cicloalquila, 4-tetrahidropiranila e 4-piperidinila; R^ 3^ é hidrogênio ou (C~ 1~-C~ 6~)alquila; e Y é um substituinte em qualquer dos átomos de carbono do anel feníla capaz de suportar uma ligação adicional, preferencialmente de 1 a 2 substituintes (mais preferencialmente um substituinte, o mais preferencialmente um substituinte na posição 4) no anel fenílico, independentemente selecionado de flúor, cloro, trifluorometila, (C~ 1~-C~ 6~)alcóxi, trifluorometóxi, difluorometóxi e (C~ 1~-C~ 6~)alquila.
BR9811868-4A 1997-08-08 1998-07-21 Derivados de ácido ariloxiarilsulfonilamino hidroxâmico BR9811868A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5520797P 1997-08-08 1997-08-08
PCT/IB1998/001113 WO1999007675A1 (en) 1997-08-08 1998-07-21 Aryloxyarylsulfonylamino hydroxamic acid derivatives

Publications (1)

Publication Number Publication Date
BR9811868A true BR9811868A (pt) 2000-08-15

Family

ID=21996358

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9811868-4A BR9811868A (pt) 1997-08-08 1998-07-21 Derivados de ácido ariloxiarilsulfonilamino hidroxâmico

Country Status (42)

Country Link
US (1) US6214872B1 (pt)
EP (1) EP1003720B1 (pt)
JP (1) JP3448275B2 (pt)
KR (1) KR100372138B1 (pt)
CN (1) CN1171866C (pt)
AP (1) AP1220A (pt)
AR (1) AR015419A1 (pt)
AT (1) ATE263147T1 (pt)
AU (1) AU730248B2 (pt)
BG (1) BG104118A (pt)
BR (1) BR9811868A (pt)
CA (1) CA2299355C (pt)
CO (1) CO4960658A1 (pt)
DE (1) DE69822839T2 (pt)
DK (1) DK1003720T3 (pt)
DZ (1) DZ2581A1 (pt)
EA (1) EA002490B1 (pt)
ES (1) ES2216293T3 (pt)
GT (1) GT199800124A (pt)
HR (1) HRP980438B1 (pt)
HU (1) HUP0002960A3 (pt)
ID (1) ID23668A (pt)
IL (1) IL134300A (pt)
IS (1) IS5340A (pt)
MA (1) MA26530A1 (pt)
MY (1) MY120235A (pt)
NO (1) NO313189B1 (pt)
NZ (1) NZ502309A (pt)
OA (1) OA11284A (pt)
PA (1) PA8456801A1 (pt)
PE (1) PE110899A1 (pt)
PL (1) PL338633A1 (pt)
PT (1) PT1003720E (pt)
SK (1) SK1362000A3 (pt)
TN (1) TNSN98150A1 (pt)
TR (1) TR200000368T2 (pt)
TW (1) TW426662B (pt)
UA (1) UA61963C2 (pt)
UY (2) UY25131A1 (pt)
WO (1) WO1999007675A1 (pt)
YU (1) YU1900A (pt)
ZA (1) ZA987126B (pt)

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