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BR9809661A - Reduction of aromatic halides - Google Patents

Reduction of aromatic halides

Info

Publication number
BR9809661A
BR9809661A BR9809661-3A BR9809661A BR9809661A BR 9809661 A BR9809661 A BR 9809661A BR 9809661 A BR9809661 A BR 9809661A BR 9809661 A BR9809661 A BR 9809661A
Authority
BR
Brazil
Prior art keywords
reduction
oxygen
halides
liaih4
aromatic
Prior art date
Application number
BR9809661-3A
Other languages
Portuguese (pt)
Inventor
Laszelo Czollner
Johannes Froehlich
Ulrich Jordis
Bernhard Kuenburg
Original Assignee
Sanochemia Pharmazeutika Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanochemia Pharmazeutika Ag filed Critical Sanochemia Pharmazeutika Ag
Publication of BR9809661A publication Critical patent/BR9809661A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B31/00Reduction in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C07C1/26Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only halogen atoms as hetero-atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/08Hydrogen atoms or radicals containing only hydrogen and carbon atoms
    • C07D333/10Thiophene

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Patente de Invenção: <B>"REDUçãO DE HALOGENETOS AROMáTICOS"<D>. Para reduzir haletos (hetero)aromáticos da fórmula geral Ar-Xn (I) para produzir composto da fórmula geral Ar-Hn (II), um agente de redução, em particular um reagente de hidreto tal como hidreto de alumínio e lítio (LiAIH4) é empregado na presença de oxigênio, em particular na forma de uma mistura de oxigênio e um gás neutro. A redução na presença de oxigênio produziu produções favoráveis dentro de tempos de reação curtos, mesmo na escala semi-industrial e industrial. A redução com LiAIH4 na presença de oxigênio é adequada para redução de haletos heteroaromáticos complexos, por exemplo, para a redução de bromonarwedinacetal em narwedinacetal na escala industrial.Invention Patent: <B> "REDUCING AROMATIC HALOGENETES" <D>. To reduce aromatic (hetero) halides of the general formula Ar-Xn (I) to produce a compound of the general formula Ar-Hn (II), a reducing agent, in particular a hydride reagent such as lithium aluminum hydride (LiAIH4) it is used in the presence of oxygen, in particular in the form of a mixture of oxygen and a neutral gas. The reduction in the presence of oxygen produced favorable yields within short reaction times, even on a semi-industrial and industrial scale. The reduction with LiAIH4 in the presence of oxygen is suitable for the reduction of complex heteroaromatic halides, for example, for the reduction of bromonarwedinacetal in narwedinacetal on an industrial scale.

BR9809661-3A 1997-05-21 1998-04-30 Reduction of aromatic halides BR9809661A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0086597A AT405051B (en) 1997-05-21 1997-05-21 REDUCTION OF AROMATIC HALOGENIDE
PCT/AT1998/000112 WO1998052885A1 (en) 1997-05-21 1998-04-30 Reduction of aromatic halogenides

Publications (1)

Publication Number Publication Date
BR9809661A true BR9809661A (en) 2000-07-11

Family

ID=3501602

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809661-3A BR9809661A (en) 1997-05-21 1998-04-30 Reduction of aromatic halides

Country Status (15)

Country Link
EP (1) EP0983215A1 (en)
JP (1) JP2001525828A (en)
KR (1) KR20010012795A (en)
CN (1) CN1257467A (en)
AT (1) AT405051B (en)
AU (1) AU7012798A (en)
BG (1) BG103880A (en)
BR (1) BR9809661A (en)
CA (1) CA2289992A1 (en)
HU (1) HUP0004681A2 (en)
NO (1) NO995494D0 (en)
NZ (1) NZ500733A (en)
PL (1) PL336906A1 (en)
SK (1) SK158399A3 (en)
WO (1) WO1998052885A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006018703A2 (en) * 2004-08-16 2006-02-23 Ranbaxy Laboratories Limited Processes for preparation of narwedine and its use in the synthesis of galantamine
WO2012073973A1 (en) * 2010-12-02 2012-06-07 横浜ゴム株式会社 Tire equipped with information acquisition device
CN107602318B (en) * 2017-09-08 2020-06-05 郑州大学 A method for liquid-phase reductive dehalogenation of halogenated aromatic hydrocarbons under mild conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3839329A1 (en) * 1988-11-22 1990-05-31 Basf Ag METHOD FOR THE REDUCTIVE ENTHALOGENATION OF AROMATES

Also Published As

Publication number Publication date
JP2001525828A (en) 2001-12-11
PL336906A1 (en) 2000-07-17
NO995494L (en) 1999-11-10
HUP0004681A2 (en) 2001-04-28
WO1998052885A1 (en) 1998-11-26
AT405051B (en) 1999-05-25
BG103880A (en) 2000-06-30
CN1257467A (en) 2000-06-21
EP0983215A1 (en) 2000-03-08
KR20010012795A (en) 2001-02-26
NO995494D0 (en) 1999-11-10
NZ500733A (en) 2001-03-30
AU7012798A (en) 1998-12-11
SK158399A3 (en) 2000-07-11
CA2289992A1 (en) 1998-11-26
ATA86597A (en) 1998-09-15

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]