BR9808219A - Processos de identificação e de isolamento de glóbulos vermelhos fetais ou embriÈnicos e de determinação de uma anormalidade fetal, kit de partes para determinação de uma anormalidade fetal e uso de uma unidade de ligação e de um meio - Google Patents
Processos de identificação e de isolamento de glóbulos vermelhos fetais ou embriÈnicos e de determinação de uma anormalidade fetal, kit de partes para determinação de uma anormalidade fetal e uso de uma unidade de ligação e de um meioInfo
- Publication number
- BR9808219A BR9808219A BR9808219-1A BR9808219A BR9808219A BR 9808219 A BR9808219 A BR 9808219A BR 9808219 A BR9808219 A BR 9808219A BR 9808219 A BR9808219 A BR 9808219A
- Authority
- BR
- Brazil
- Prior art keywords
- fetal
- determining
- embryonic
- blood cells
- red blood
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Treatment Of Sludge (AREA)
- Eye Examination Apparatus (AREA)
Abstract
"PROCESSOS DE IDENTIFICAçãO E DE ISOLAMENTO DE GLóBULOS VERMELHOS FETAIS OU EMBRIÈNICOS E DE DETERMINAçãO DE UMA ANORMALIDADE FETAL, KIT DE PARTES PARA DETERMINAçãO DE UMA ANORMALIDADE FETAL E USO DE UMA UNIDADE DE LIGAçãO E DE UM MEIO" Um processo de identificação de glóbulos vermelhos fetais ou embriónicos em uma amostra contendo células sang³íneas maternais e glóbulos vermelhos fetais ou embriónicos ou ambos, compreendendo o processo a determinação de qual célula ou quais células conté(ê)m ou expressa(m) e componente de fígado de adulto. Um processo de isolamento de glóbulos vermelhos fetais ou embriónicos de uma amostra contendo células sang³íneas maternais e glóbulos vermelhos fetais ou embriónicos ou ambos, compreendendo o processo o isolamento de células que contêm ou expressam um componente de fígado de adulto. Um processo de determinação de uma anormalidade fetal, compreendendo o processo com os processos acima e a análise das citadas células fetais iniciais ou embriónicas para a citada anormalidade. Uso de um meio para determinação de se uma célula contém ou expressa um componente de fígado de adulto para identificação ou isolamento de um glóbulo vermelho fetal ou embriónico
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9704876.3A GB9704876D0 (en) | 1997-03-08 | 1997-03-08 | Diagnostic methods |
| US6752097P | 1997-12-04 | 1997-12-04 | |
| PCT/GB1998/000656 WO1998040746A1 (en) | 1997-03-08 | 1998-03-03 | Prenatal diagnostic methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9808219A true BR9808219A (pt) | 2000-05-16 |
Family
ID=26311146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9808219-1A BR9808219A (pt) | 1997-03-08 | 1998-03-03 | Processos de identificação e de isolamento de glóbulos vermelhos fetais ou embriÈnicos e de determinação de uma anormalidade fetal, kit de partes para determinação de uma anormalidade fetal e uso de uma unidade de ligação e de um meio |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6331395B1 (pt) |
| EP (1) | EP0974056B1 (pt) |
| JP (1) | JP2001514751A (pt) |
| CN (1) | CN1260046A (pt) |
| AT (1) | ATE308755T1 (pt) |
| AU (1) | AU738401B2 (pt) |
| BR (1) | BR9808219A (pt) |
| CA (1) | CA2283416A1 (pt) |
| DE (1) | DE69832161T2 (pt) |
| DK (1) | DK0974056T3 (pt) |
| ES (1) | ES2255150T3 (pt) |
| GB (1) | GB2326943B (pt) |
| NO (1) | NO994358D0 (pt) |
| PL (1) | PL335543A1 (pt) |
| WO (1) | WO1998040746A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4745200A (en) * | 1999-05-25 | 2000-12-12 | Britta Christensen | Isolation and culturing of fetal cells |
| GB0022017D0 (en) * | 2000-09-08 | 2000-10-25 | Univ Dundee | Cell assays |
| WO2004029221A2 (en) | 2002-09-27 | 2004-04-08 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
| GB0415644D0 (en) * | 2004-07-13 | 2004-08-18 | Riverside Biosciences Ltd | Monoclonal antibody |
| US20060105353A1 (en) * | 2004-11-16 | 2006-05-18 | Jalal Syed M | Non-invasive prenatal fetal cell diagnostic method |
| US7439062B2 (en) * | 2004-12-23 | 2008-10-21 | Biocept, Inc. | Beads for capturing target cells from bodily fluid |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US8614419B2 (en) * | 2008-03-28 | 2013-12-24 | The Ohio State University | Rapid diagnosis of a disease condition using infrared spectroscopy |
| WO2009121054A2 (en) | 2008-03-28 | 2009-10-01 | The Ohio State University | Rapid diagnosis of a disease condition using infrared spectroscopy |
| EP2526183A4 (en) | 2010-01-21 | 2017-05-03 | Biocep Ltd. | Magnetic separation of rare cells |
| US8774488B2 (en) | 2010-03-11 | 2014-07-08 | Cellscape Corporation | Method and device for identification of nucleated red blood cells from a maternal blood sample |
| CN106793771B (zh) * | 2014-09-25 | 2021-01-05 | 深圳华大基因科技有限公司 | 用于孕妇外周血样的保存液和孕妇外周血样的保存方法 |
| CN111948404B (zh) * | 2020-08-03 | 2023-04-07 | 融智生物科技(青岛)有限公司 | 用于筛查地中海贫血的特征蛋白标记组合物、质谱模型及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991007660A1 (en) * | 1989-11-13 | 1991-05-30 | Children's Medical Center Corporation | Non-invasive method for isolation and detection of fetal dna |
| US5641628A (en) * | 1989-11-13 | 1997-06-24 | Children's Medical Center Corporation | Non-invasive method for isolation and detection of fetal DNA |
| US5153117A (en) * | 1990-03-27 | 1992-10-06 | Genetype A.G. | Fetal cell recovery method |
| DE4222573C1 (pt) * | 1992-05-16 | 1993-08-12 | Dorothee Dr. 4400 Muenster De Ahlert | |
| US5460942A (en) * | 1993-09-10 | 1995-10-24 | The United States Of America As Represented By The Department Of Health And Human Services | The catalytic moiety of the glucose-6-phosphatase system: the gene and protein and related mutations |
| US5714325A (en) * | 1993-09-24 | 1998-02-03 | New England Medical Center Hospitals | Prenatal diagnosis by isolation of fetal granulocytes from maternal blood |
| JPH10507632A (ja) * | 1994-09-20 | 1998-07-28 | ミルテニー バイオテック,インコーポレイティド | 母体からの胎児血液の濃縮 |
| GB9603249D0 (en) * | 1996-02-16 | 1996-04-17 | Univ Nottingham | Foetal cell analysis |
| DE19721113A1 (de) * | 1996-05-20 | 1997-11-27 | Sumitomo Chemical Co | Diagnosekit |
| US5731156A (en) * | 1996-10-21 | 1998-03-24 | Applied Imaging, Inc. | Use of anti-embryonic hemoglobin antibodies to identify fetal cells |
| US5859699A (en) | 1997-02-07 | 1999-01-12 | Arcturus Engineering, Inc. | Laser capture microdissection analysis vessel |
-
1998
- 1998-03-03 GB GB9820505A patent/GB2326943B/en not_active Expired - Fee Related
- 1998-03-03 BR BR9808219-1A patent/BR9808219A/pt not_active Application Discontinuation
- 1998-03-03 WO PCT/GB1998/000656 patent/WO1998040746A1/en not_active Ceased
- 1998-03-03 CN CN98804908A patent/CN1260046A/zh active Pending
- 1998-03-03 DK DK98908222T patent/DK0974056T3/da active
- 1998-03-03 EP EP98908222A patent/EP0974056B1/en not_active Expired - Lifetime
- 1998-03-03 AT AT98908222T patent/ATE308755T1/de not_active IP Right Cessation
- 1998-03-03 JP JP53933798A patent/JP2001514751A/ja active Pending
- 1998-03-03 AU AU66303/98A patent/AU738401B2/en not_active Ceased
- 1998-03-03 PL PL98335543A patent/PL335543A1/xx not_active Application Discontinuation
- 1998-03-03 DE DE69832161T patent/DE69832161T2/de not_active Expired - Fee Related
- 1998-03-03 ES ES98908222T patent/ES2255150T3/es not_active Expired - Lifetime
- 1998-03-03 CA CA002283416A patent/CA2283416A1/en not_active Abandoned
-
1999
- 1999-09-08 NO NO994358A patent/NO994358D0/no unknown
- 1999-09-08 US US09/392,055 patent/US6331395B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0974056B1 (en) | 2005-11-02 |
| DK0974056T3 (da) | 2005-12-05 |
| CN1260046A (zh) | 2000-07-12 |
| NO994358L (no) | 1999-09-08 |
| CA2283416A1 (en) | 1998-09-17 |
| DE69832161T2 (de) | 2006-04-20 |
| GB2326943A (en) | 1999-01-06 |
| GB2326943B (en) | 1999-06-16 |
| AU738401B2 (en) | 2001-09-20 |
| DE69832161D1 (de) | 2005-12-08 |
| JP2001514751A (ja) | 2001-09-11 |
| EP0974056A1 (en) | 2000-01-26 |
| ATE308755T1 (de) | 2005-11-15 |
| US6331395B1 (en) | 2001-12-18 |
| PL335543A1 (en) | 2000-04-25 |
| GB9820505D0 (en) | 1998-11-11 |
| ES2255150T3 (es) | 2006-06-16 |
| WO1998040746A1 (en) | 1998-09-17 |
| NO994358D0 (no) | 1999-09-08 |
| AU6630398A (en) | 1998-09-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. |