[go: up one dir, main page]

BR9803717A - ácidos indol-2-carbocìlicos substituìdos como inibidores de glucosil transferase. - Google Patents

ácidos indol-2-carbocìlicos substituìdos como inibidores de glucosil transferase.

Info

Publication number
BR9803717A
BR9803717A BR9803717-0A BR9803717A BR9803717A BR 9803717 A BR9803717 A BR 9803717A BR 9803717 A BR9803717 A BR 9803717A BR 9803717 A BR9803717 A BR 9803717A
Authority
BR
Brazil
Prior art keywords
indole
transferase inhibitors
glucosyl transferase
acids substituted
carbocyclic acids
Prior art date
Application number
BR9803717-0A
Other languages
English (en)
Inventor
Susan Froshauer
Steven Wayne Goldstein
William George Stirtan
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR9803717A publication Critical patent/BR9803717A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Patente de Invenção: <B>''áCIDOS INDOL-2-CARBOXìLICOS SUBSTITUìDOS COMO INIBIDORES DE GLUCOSIL TRANSFERASE''<D>. ácidos 5-carbonilaril e 5-carbonilalquil e 5-carbonilcicloalquil-3-alquil-indol-2-carboxílicos são úteis como inibidores de UGGTase.
BR9803717-0A 1997-07-29 1998-07-28 ácidos indol-2-carbocìlicos substituìdos como inibidores de glucosil transferase. BR9803717A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5414097P 1997-07-29 1997-07-29

Publications (1)

Publication Number Publication Date
BR9803717A true BR9803717A (pt) 2000-04-11

Family

ID=21989027

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9803717-0A BR9803717A (pt) 1997-07-29 1998-07-28 ácidos indol-2-carbocìlicos substituìdos como inibidores de glucosil transferase.

Country Status (5)

Country Link
US (1) US5981762A (pt)
EP (1) EP0894789A1 (pt)
JP (1) JPH11100367A (pt)
BR (1) BR9803717A (pt)
CA (1) CA2243882A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008156573A1 (en) 2007-06-12 2008-12-24 Provid Pharmaceuticals, Inc. Kinase inhibitors, compositions thereof, and methods of use therewith
US9278089B2 (en) 2011-10-26 2016-03-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Method of treating HCV infection with a small molecule CHK2 inhibitor

Also Published As

Publication number Publication date
EP0894789A1 (en) 1999-02-03
CA2243882A1 (en) 1999-01-29
JPH11100367A (ja) 1999-04-13
US5981762A (en) 1999-11-09

Similar Documents

Publication Publication Date Title
BR9908280A (pt) Inibidores de enzimas de fosfolipase
DE69841285D1 (de) Bipolares Elektrodeninstrument
BR9808491A (pt) Compostos calcilìticos
BR9710994A (pt) Derivados anticonvulsivos úteis no tratamento de obesidade.
BR9902086A (pt) Formulações farmacêuticas.
IT1311994B1 (it) Derivati di amminoacidi.
MA26812A1 (fr) Pyrimidine-2,4,6-triones inhibitrices de metalloproteinases
ATE546139T1 (de) Isoprentransferase proteine inhibitoren
BR9915515B1 (pt) composiÇço curÁvel de multicomponentes.
EP0891350A4 (en) INHIBIOTS OF FARNESYL PROTEIN TRANSFERASE
BR9909242A (pt) Inibidores de fosfolipase a2
ES2195970T3 (es) L-ribavirina y usos de la misma.
ATE264863T1 (de) 28-epirapaloge
ID24076A (id) Inhibitor-inhibitor protein transferase farnesil
BR9810870A (pt) Regulação de expressão de quinolato fosforibosil transferase
EP0668856A4 (en) INHIBITORS OF FARNESYL PROTEIN TRANSFERASE.
PE14199A1 (es) Agonistas de 5-ht1f
NO20004550D0 (no) Enzyminhibitorer
PT1000048E (pt) Derivados substituidos do 1,2,3,4-tetrahidronaftaleno
BR9608012A (pt) Agentes de amidino cíclicos úteis como inbidores da sintase do óxido nítrico
EP0904080A4 (en) INHIBITORS OF FARNESYL PROTEIN TRANSFERASE
DE69935468D1 (de) Erzeugen von Nachrichtensignalen
PT869121E (pt) Derivados de propanolamina hipolipidemicos
EP0783305A4 (en) INHIBITORS OF FARNESYL PROTEIN TRANSFERASE
BR9907655A (pt) Derivados de ácido di-hidróxi-hexanóico

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 4A,5A,6A,7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1860 DE 29/08/2006.