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BR9801085A - Processo para a preparação de moenomicina a. - Google Patents

Processo para a preparação de moenomicina a.

Info

Publication number
BR9801085A
BR9801085A BR9801085-9A BR9801085A BR9801085A BR 9801085 A BR9801085 A BR 9801085A BR 9801085 A BR9801085 A BR 9801085A BR 9801085 A BR9801085 A BR 9801085A
Authority
BR
Brazil
Prior art keywords
moenomycin
preparation
chromatography
fermenting
prepared
Prior art date
Application number
BR9801085-9A
Other languages
English (en)
Inventor
Laszlo Dr Vertesy
Andreas Dr Straerk
Eberhard Dr Ehlers
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of BR9801085A publication Critical patent/BR9801085A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

Patente de Invenção: <B>"PROCESSO PARA A PREPARAçãO DE MOENOMICINA A"<D>. Moenomicina A pode ser preparada através de fermentação de um microorganismo produtor de moenomicinaf e pela separação posterior de moenomicina A dos componentes restantes do filtrado de cultura por meio de cromatografia, sendo que como material de cromatografia é empregado um trocador de ânions.
BR9801085-9A 1997-04-17 1998-04-17 Processo para a preparação de moenomicina a. BR9801085A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19716013 1997-04-17

Publications (1)

Publication Number Publication Date
BR9801085A true BR9801085A (pt) 2000-01-11

Family

ID=7826763

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9801085-9A BR9801085A (pt) 1997-04-17 1998-04-17 Processo para a preparação de moenomicina a.

Country Status (8)

Country Link
US (1) US5986089A (pt)
EP (1) EP0872556A3 (pt)
JP (1) JPH10295396A (pt)
KR (1) KR100470524B1 (pt)
CN (1) CN1134449C (pt)
AU (1) AU6194298A (pt)
BR (1) BR9801085A (pt)
CA (1) CA2234778A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2199401B1 (en) * 2006-05-16 2012-12-12 The Kitasato Institute Novel K04-0144 substances and process for production thereof
US9115358B2 (en) 2006-08-11 2015-08-25 President And Fellows Of Harvard College Moenomycin biosynthesis-related compositions and methods of use thereof
WO2009046314A2 (en) * 2007-10-04 2009-04-09 President And Fellows Of Harvard College Moenomycin analogs, methods of synthesis, and uses thereof
CN101830942B (zh) * 2010-05-13 2012-07-25 浙江钱江生物化学股份有限公司 一种黄霉素的后处理方法
CN102603817B (zh) * 2012-02-10 2014-06-18 重庆出入境检验检疫局检验检疫技术中心 一种从黄霉素预混剂中提取、纯化制备黄霉素a对照品的方法
US9902985B2 (en) 2012-04-06 2018-02-27 President And Fellows Of Harvard College Chemoenzymatic methods for synthesizing moenomycin analogs
US9273084B2 (en) 2012-04-06 2016-03-01 President And Fellows Of Harvard College Moenomycin analogs, methods of synthesis, and uses thereof
EP2850091A1 (en) 2012-04-06 2015-03-25 President and Fellows of Harvard College Methods and compounds for identifying glycosyltransferase inhibitors
CN105131053B (zh) * 2015-07-21 2017-08-11 西北大学 一种黄霉素a组分的分离纯化方法
CN105037451B (zh) * 2015-07-22 2017-10-27 西北大学 一种超滤处理黄霉素发酵液的方法
CN107586310B (zh) * 2017-09-15 2020-04-14 浙江浙大阳光科技有限公司 一种黄霉素的提取工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617466A1 (de) * 1951-01-28 1971-04-08 Hoechst Ag Verfahren zur Trennung von Moenomyein-Komponenten
DE1113791B (de) * 1960-02-10 1961-09-14 Hoechst Ag Herstellung und Gewinnung des Antibiotikums Moenomycin
GB1068639A (en) * 1964-09-21 1967-05-10 Hoechst Ag A purified form of the antibiotic moenomycin and a process for its manufacture
DE3467171D1 (en) * 1983-05-21 1987-12-10 Hoechst Ag Moenomycin-a derivatives, their preparation and their use as antibiotics
DE3704659A1 (de) * 1987-02-14 1988-08-25 Hoechst Ag Moenomycin c(pfeil abwaerts)3(pfeil abwaerts)-derivate, verfahren zu ihrer herstellung und ihre verwendung als antibiotika
EP0355679B1 (de) * 1988-08-20 1996-02-28 Hoechst Aktiengesellschaft Neuer Mikroorganismus zum Abbau von Moenomycinen, Verfahren zum Abbau sowie die Verwendung der Abbauprodukte

Also Published As

Publication number Publication date
AU6194298A (en) 1998-10-22
JPH10295396A (ja) 1998-11-10
US5986089A (en) 1999-11-16
MX9802979A (es) 1998-12-31
CA2234778A1 (en) 1998-10-17
CN1134449C (zh) 2004-01-14
KR19980081416A (ko) 1998-11-25
KR100470524B1 (ko) 2005-05-09
EP0872556A3 (de) 2000-06-14
EP0872556A2 (de) 1998-10-21
CN1196356A (zh) 1998-10-21

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ART. 36 DA LPI ( LEI 9279/96 ) 2O , O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAOPATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR.

B15K Others concerning applications: alteration of classification

Ipc: C12P 19/26 (2006.01), C12P 19/44 (2006.0