BR9713914A - Composto, uso do mesmo, composição farmacêutica, e processo para tratar um paciente sofrendo de um distúrbio que é susceptìvel a tratamento com um agonista da trombopoietina. - Google Patents
Composto, uso do mesmo, composição farmacêutica, e processo para tratar um paciente sofrendo de um distúrbio que é susceptìvel a tratamento com um agonista da trombopoietina.Info
- Publication number
- BR9713914A BR9713914A BR9713914-9A BR9713914A BR9713914A BR 9713914 A BR9713914 A BR 9713914A BR 9713914 A BR9713914 A BR 9713914A BR 9713914 A BR9713914 A BR 9713914A
- Authority
- BR
- Brazil
- Prior art keywords
- treat
- disorder
- susceptible
- compound
- treatment
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940123936 Thrombopoietin agonist Drugs 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000005763 Thrombopoietin Receptors Human genes 0.000 abstract 1
- 108010070774 Thrombopoietin Receptors Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 210000001185 bone marrow Anatomy 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000014951 hematologic disease Diseases 0.000 abstract 1
- 238000001959 radiotherapy Methods 0.000 abstract 1
- 206010043554 thrombocytopenia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/524—Thrombopoietin, i.e. C-MPL ligand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
"COMPOSTO, USO DO MESMO, COMPOSIçãO FARMACêUTICA, E, PROCESSO PARA TRATAR UM PACIENTE SOFRENDO DE UM DISTúRBIO QUE é SUSCEPTìVEL A TRATAMENTO COM UM AGONISTA DA TROMBOPOIETINA". São descritos peptídeos e compostos que se ligam ao e ativam o receptor da trombopoietina. Tais peptídeos e compostos são úteis nos processos para tratar distúrbios hematológicos e, particularmente, a trombocitopenia resultante da quimioterapia, terapia de radiação ou transfusões da medula óssea, bem como em processos diagnósticos empregando peptídeos e compostos rotulados.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/764640 | 1996-12-11 | ||
| US08/764,640 US5869451A (en) | 1995-06-07 | 1996-12-11 | Peptides and compounds that bind to a receptor |
| PCT/EP1997/006850 WO1998025965A2 (en) | 1996-12-11 | 1997-12-09 | Peptides and compounds that bind to the thrombopoietin receptor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR9713914A true BR9713914A (pt) | 2000-02-29 |
| BRPI9713914B1 BRPI9713914B1 (pt) | 2017-06-20 |
| BRPI9713914B8 BRPI9713914B8 (pt) | 2021-05-25 |
Family
ID=25071323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI9713914-9A BRPI9713914B1 (pt) | 1996-12-11 | 1997-12-09 | Composition, use of the same, and, pharmaceutical composition |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US5869451A (pt) |
| EP (3) | EP0948539B1 (pt) |
| JP (1) | JP4128225B2 (pt) |
| KR (3) | KR100679576B1 (pt) |
| CN (1) | CN100379760C (pt) |
| AR (2) | AR010752A1 (pt) |
| AT (1) | ATE420893T1 (pt) |
| AU (1) | AU725731B2 (pt) |
| BR (1) | BRPI9713914B1 (pt) |
| CA (1) | CA2274149C (pt) |
| CO (1) | CO5080768A1 (pt) |
| DE (1) | DE69739219D1 (pt) |
| ES (1) | ES2321038T3 (pt) |
| HR (1) | HRP970683B1 (pt) |
| MA (1) | MA26454A1 (pt) |
| PA (1) | PA8442601A1 (pt) |
| PE (1) | PE27599A1 (pt) |
| SV (1) | SV1997000104A (pt) |
| TN (1) | TNSN97201A1 (pt) |
| TR (2) | TR199901971T2 (pt) |
| TW (1) | TW515804B (pt) |
| UY (1) | UY24805A1 (pt) |
| WO (1) | WO1998025965A2 (pt) |
| ZA (1) | ZA9711045B (pt) |
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